TW200616616A - Paclitaxel aqueous injection solution and methods for preparing the same - Google Patents
Paclitaxel aqueous injection solution and methods for preparing the sameInfo
- Publication number
- TW200616616A TW200616616A TW094118128A TW94118128A TW200616616A TW 200616616 A TW200616616 A TW 200616616A TW 094118128 A TW094118128 A TW 094118128A TW 94118128 A TW94118128 A TW 94118128A TW 200616616 A TW200616616 A TW 200616616A
- Authority
- TW
- Taiwan
- Prior art keywords
- paclitaxel
- pharmaceutical composition
- preparing
- methods
- same
- Prior art date
Links
- 229930012538 Paclitaxel Natural products 0.000 title abstract 4
- 229960001592 paclitaxel Drugs 0.000 title abstract 4
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 title abstract 4
- 238000002347 injection Methods 0.000 title 1
- 239000007924 injection Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000243 solution Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000004359 castor oil Substances 0.000 abstract 1
- 235000019438 castor oil Nutrition 0.000 abstract 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/995,262 US7361683B2 (en) | 2004-11-24 | 2004-11-24 | Paclitaxel aqueous injection solution and methods for preparing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
TW200616616A true TW200616616A (en) | 2006-06-01 |
TWI303566B TWI303566B (en) | 2008-12-01 |
Family
ID=34933891
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW094118128A TWI303566B (en) | 2004-11-24 | 2005-06-02 | Paclitaxel aqueous injection solution and methods for preparing the same |
Country Status (6)
Country | Link |
---|---|
US (1) | US7361683B2 (zh) |
EP (1) | EP1666069B1 (zh) |
JP (1) | JP4805599B2 (zh) |
AT (1) | ATE405292T1 (zh) |
DE (1) | DE602005009110D1 (zh) |
TW (1) | TWI303566B (zh) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE539761T1 (de) * | 2006-06-29 | 2012-01-15 | Arigen Pharmaceuticals Inc | Mittel für injektionszwecke mit einem antibiotikum und das mittel enthaltende lösung zur injektion |
GB2445746A (en) * | 2007-01-17 | 2008-07-23 | Texcontor Ets | Use of carbonated water as a solvent for freeze drying, and method of purification comprising dissolution of material in carbonated water and freeze drying |
DE102007021862A1 (de) * | 2007-05-10 | 2008-11-13 | Merck Patent Gmbh | Wässrige pharmazeutische Zubereitung |
CN101396354B (zh) * | 2007-09-30 | 2010-12-01 | 江苏恒瑞医药股份有限公司 | 一种稳定的塔三烷类化合物液体组合物及其制备方法和其应用 |
CN104203251B (zh) * | 2012-03-22 | 2017-05-31 | 盐水港精糖株式会社 | 内包紫杉醇单糖苷和/或紫杉萜单糖苷的脂质体的制造方法 |
WO2014028704A1 (en) * | 2012-08-15 | 2014-02-20 | Yung Shin Pharm. Ind. Co., Ltd. | Stable pharmaceutical formulation of cabazitaxel |
TW201420130A (zh) * | 2012-09-26 | 2014-06-01 | Neochemir Inc | 溶解有二氧化碳之液狀藥劑及其投藥方法 |
WO2015106094A1 (en) * | 2014-01-10 | 2015-07-16 | Atossa Genetics Inc. | Transpapillary methods and compositions for diagnosing and treating breast conditions |
CN114588270A (zh) | 2015-09-16 | 2022-06-07 | Dfb索里亚有限责任公司 | 包含紫杉烷类纳米颗粒的组合物及其用途 |
WO2018170196A1 (en) | 2017-03-15 | 2018-09-20 | Dfb Soria, Llc | Topical therapy for the treatment of skin malignancies using nanoparticles of taxanes |
EP3765035A4 (en) | 2018-03-16 | 2021-10-27 | DFB Soria, LLC | TOPICAL THERAPY FOR TREATMENT OF CERVICAL INTRAEPITHELIAL NEOPLASIA (CIN) AND ETERNAL CANCER USING TAXANNANO PARTICLES |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994012031A1 (en) * | 1992-11-27 | 1994-06-09 | Napro Biotherapeutics, Inc. | Injectable composition |
TW406020B (en) | 1993-09-29 | 2000-09-21 | Bristol Myers Squibb Co | Stabilized pharmaceutical composition and its method for preparation and stabilizing solvent |
JP4000426B2 (ja) * | 1996-05-08 | 2007-10-31 | 株式会社大塚製薬工場 | 輸液製剤 |
JP3375518B2 (ja) * | 1997-06-23 | 2003-02-10 | 清水製薬株式会社 | 注射剤 |
JP2003201242A (ja) * | 2001-12-28 | 2003-07-18 | Shimizu Pharmaceutical Co Ltd | 重曹リンゲル様液剤 |
-
2004
- 2004-11-24 US US10/995,262 patent/US7361683B2/en not_active Expired - Fee Related
-
2005
- 2005-02-23 EP EP05003915A patent/EP1666069B1/en not_active Not-in-force
- 2005-02-23 DE DE602005009110T patent/DE602005009110D1/de active Active
- 2005-02-23 AT AT05003915T patent/ATE405292T1/de not_active IP Right Cessation
- 2005-04-15 JP JP2005118226A patent/JP4805599B2/ja not_active Expired - Fee Related
- 2005-06-02 TW TW094118128A patent/TWI303566B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ATE405292T1 (de) | 2008-09-15 |
US20060111432A1 (en) | 2006-05-25 |
DE602005009110D1 (de) | 2008-10-02 |
EP1666069B1 (en) | 2008-08-20 |
JP2006143699A (ja) | 2006-06-08 |
US7361683B2 (en) | 2008-04-22 |
JP4805599B2 (ja) | 2011-11-02 |
TWI303566B (en) | 2008-12-01 |
EP1666069A1 (en) | 2006-06-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Annulment or lapse of patent due to non-payment of fees |