TW200501943A - Escitalopram hydrobromide and a method for the preparation thereof - Google Patents

Escitalopram hydrobromide and a method for the preparation thereof

Info

Publication number
TW200501943A
TW200501943A TW092136380A TW92136380A TW200501943A TW 200501943 A TW200501943 A TW 200501943A TW 092136380 A TW092136380 A TW 092136380A TW 92136380 A TW92136380 A TW 92136380A TW 200501943 A TW200501943 A TW 200501943A
Authority
TW
Taiwan
Prior art keywords
preparation
escitalopram hydrobromide
escitalopram
hydrobromide
citalopram
Prior art date
Application number
TW092136380A
Other languages
English (en)
Chinese (zh)
Inventor
Robert Dancer
Hans Petersen
Peter Ellegaard
Lawrence Martel
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32668635&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TW200501943(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of TW200501943A publication Critical patent/TW200501943A/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Addiction (AREA)
  • Anesthesiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Nutrition Science (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
TW092136380A 2002-12-23 2003-12-22 Escitalopram hydrobromide and a method for the preparation thereof TW200501943A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200202005 2002-12-23

Publications (1)

Publication Number Publication Date
TW200501943A true TW200501943A (en) 2005-01-16

Family

ID=32668635

Family Applications (1)

Application Number Title Priority Date Filing Date
TW092136380A TW200501943A (en) 2002-12-23 2003-12-22 Escitalopram hydrobromide and a method for the preparation thereof

Country Status (32)

Country Link
US (1) US20040167209A1 (enExample)
EP (1) EP1578738B1 (enExample)
JP (2) JP4658613B2 (enExample)
KR (1) KR20050086933A (enExample)
CN (1) CN100349885C (enExample)
AR (1) AR042652A1 (enExample)
AT (1) ATE388947T1 (enExample)
AU (1) AU2003287919B2 (enExample)
BR (1) BR0317623A (enExample)
CA (1) CA2511142A1 (enExample)
CY (1) CY1107451T1 (enExample)
DE (1) DE60319739T2 (enExample)
DK (1) DK1578738T3 (enExample)
EA (1) EA013116B1 (enExample)
EG (1) EG24729A (enExample)
ES (1) ES2298595T3 (enExample)
IL (1) IL169125A0 (enExample)
IS (1) IS2654B (enExample)
ME (1) MEP5808A (enExample)
MX (1) MXPA05005772A (enExample)
MY (1) MY135468A (enExample)
NO (1) NO20053595L (enExample)
NZ (1) NZ540281A (enExample)
PE (1) PE20040924A1 (enExample)
PL (1) PL378275A1 (enExample)
PT (1) PT1578738E (enExample)
RS (1) RS51092B (enExample)
TW (1) TW200501943A (enExample)
UA (1) UA80170C2 (enExample)
UY (1) UY28148A1 (enExample)
WO (1) WO2004056791A1 (enExample)
ZA (1) ZA200504109B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0317623A (pt) * 2002-12-23 2005-11-29 Lundbeck & Co As H Escitalopram, composição farmacêutica, e, uso de hidrobrometo de escitalopram
US20050137255A1 (en) * 2002-12-23 2005-06-23 H. Lundbeck A/S Crystalline escitalopram hydrobromide and methods for preparing the same
NZ549100A (en) * 2004-03-05 2010-02-26 Lundbeck & Co As H Crystalline composition containing escitalopram oxalate
TWI358407B (en) 2005-06-22 2012-02-21 Lundbeck & Co As H Crystalline base of escitalopram and orodispersibl
US7834201B2 (en) 2005-06-22 2010-11-16 H. Lundbeck A/S Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
US20070112075A1 (en) * 2005-10-14 2007-05-17 Forest Laboratories, Inc. Stable pharmaceutical formulations containing escitalopram and bupropion
EP1954257A4 (en) * 2005-10-14 2009-05-20 Lundbeck & Co As H METHOD FOR TREATING DISORDERS OF THE CENTRAL NERVOUS SYSTEM WITH A LOW-DOSED COMBINATION OF ESCITALOPRAM AND BUPROPION
TW200812993A (en) * 2006-05-02 2008-03-16 Lundbeck & Co As H New uses of escitalopram
JP5501615B2 (ja) * 2006-07-11 2014-05-28 田辺三菱製薬株式会社 モルホリン化合物の塩
WO2008059514A2 (en) * 2006-07-31 2008-05-22 Cadila Healthcare Limited Process for preparing escitalopram
FR3006594A1 (fr) * 2013-06-11 2014-12-12 Sorin Crm Sas Microsonde implantable de detection/stimulation incorporant un agent anti-inflammatoire
CN108976188B (zh) * 2017-06-05 2022-12-06 上海奥博生物医药股份有限公司 一种艾司西酞普兰双羟萘酸盐新的制备方法
RU2020111694A (ru) * 2017-10-09 2021-11-12 Тева Фармасьютикал Индастриз Лтд. Новые соли и твердые формы эсциталопрама
EP4277661A1 (en) 2021-01-18 2023-11-22 Anton Frenkel Pharmaceutical dosage form

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US34712A (en) * 1862-03-18 James h
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) * 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) * 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
ATE230738T1 (de) * 1998-10-20 2003-01-15 Lundbeck & Co As H Verfahren zur herstellung von citalopram
AR021155A1 (es) * 1999-07-08 2002-06-12 Lundbeck & Co As H Tratamiento de desordenes neuroticos
PT1298124E (pt) * 1999-10-25 2007-05-31 Lundbeck & Co As H Método para a preparação de citalopram
US6977306B2 (en) * 2000-05-02 2005-12-20 Sumitomo Chemical Company, Limited Citalopram hydrobromide crystal and method for crystallization thereof
JP2002020379A (ja) * 2000-05-02 2002-01-23 Sumika Fine Chemicals Co Ltd シタロプラム臭化水素酸塩の結晶およびその結晶化方法
IES20010693A2 (en) * 2000-08-10 2002-07-10 Lundbeck & Co As H Pharmaceutical composition containing citalopram
WO2002046340A1 (de) * 2000-12-04 2002-06-13 Dr. Frische Gmbh Verfahren zur herstellung von fettsaüreestern
MXPA03008777A (es) * 2001-05-01 2004-02-12 Lundbeck & Co As H El uso de escitalopram enantiomericamente puro.
AR034612A1 (es) * 2001-06-25 2004-03-03 Lundbeck & Co As H Proceso para la preparacion del citalopram racemico y/o del s- o r-citalopram mediante la separacion de una mezcla de r- y s-citalopram
BR0317623A (pt) * 2002-12-23 2005-11-29 Lundbeck & Co As H Escitalopram, composição farmacêutica, e, uso de hidrobrometo de escitalopram
US20050174782A1 (en) * 2003-03-25 2005-08-11 Chapman Leonard T. Flashlight

Also Published As

Publication number Publication date
AR042652A1 (es) 2005-06-29
ATE388947T1 (de) 2008-03-15
DE60319739T2 (de) 2008-07-17
JP4658613B2 (ja) 2011-03-23
EA013116B1 (ru) 2010-02-26
WO2004056791A1 (en) 2004-07-08
RS20050487A (sr) 2007-06-04
IS2654B (is) 2010-08-15
AU2003287919A1 (en) 2004-07-14
ZA200504109B (en) 2006-08-30
JP2011037893A (ja) 2011-02-24
KR20050086933A (ko) 2005-08-30
CA2511142A1 (en) 2004-07-08
EP1578738B1 (en) 2008-03-12
PT1578738E (pt) 2008-04-11
DK1578738T3 (da) 2008-06-30
PE20040924A1 (es) 2004-12-11
MY135468A (en) 2008-04-30
AU2003287919B2 (en) 2009-11-12
PL378275A1 (pl) 2006-03-20
EA200501046A1 (ru) 2005-12-29
DE60319739D1 (de) 2008-04-24
CN1726202A (zh) 2006-01-25
ES2298595T3 (es) 2008-05-16
CY1107451T1 (el) 2012-12-19
CN100349885C (zh) 2007-11-21
MXPA05005772A (es) 2005-08-16
RS51092B (sr) 2010-10-31
NZ540281A (en) 2008-07-31
MEP5808A (xx) 2010-02-10
JP2006514952A (ja) 2006-05-18
EG24729A (en) 2010-06-21
UY28148A1 (es) 2004-09-30
EP1578738A1 (en) 2005-09-28
IS7848A (is) 2005-05-17
BR0317623A (pt) 2005-11-29
US20040167209A1 (en) 2004-08-26
HK1087708A1 (en) 2006-10-20
NO20053595L (no) 2005-09-05
UA80170C2 (en) 2007-08-27
IL169125A0 (en) 2009-02-11

Similar Documents

Publication Publication Date Title
CY1107451T1 (el) Υδροβρωμικον escitalopram και μεθοδος δια την παρασκευη αυτου
MXPA03005222A (es) Derivado de metanosulfonamido-benzofurano, su procedimiento de preparacion y su utilizacion como intermediario de sisntesis.
ATE289640T1 (de) Amidofunktionelle aminopolydiorganosiloxane
NO331093B1 (no) Somatostatinanaloger, fremgangsmåte for fremstilling, farmasøytisk sammensetning og anvendelse derav.
MXPA02009275A (es) Metodo para preparar dispersiones de alta presion/alto esfuerzo cortante que contienen ingredientes fisiologicamente activos.
AP1703A (en) Heparin-derived polysaccharide mixtures, preparation method and pharmaceutical compositions containing same.
MXPA04001785A (es) Benzofurano y derivados de dihidrobenzofurano utiles como agonistas de beta-3 adrenoreceptores.
ZA200309471B (en) Method for the preparation of escitalopram.
EA200400455A1 (ru) Способ приготовления быстрорастворимой дозировочной формы
AU2002305344A1 (en) Ortho-alkylphenol derived mannich detergent composition and concentrate, fuel and method thereof
AU2003236118A1 (en) An antispastic, analgetic pharmaceutical composition and the preparation method thereof as well as the quality control technique therefor
IL154776A0 (en) Method for the preparation of 21-hydroxy-6, 19-oxidoprogesterone and derivatives thereof
IL150367A0 (en) Method for the preparation of citalopram
AU2003218824A8 (en) Benzopyran derivatives substituted with secondary amines including tetrazole, method for the preparation thereof and pharmaceutical compositions containing them
AU2003201163A1 (en) Method for the preparation of lariciresinol, cyclolariciresinol and secoisolariciresinol
AU2003246840A1 (en) Anti-hiv composition, production method thereof and medicament
EA200300768A1 (ru) Фармацевтическая композиция, содержащая циталопрам
AU2002245649A1 (en) Methods, compositions and kits for preserving antigenicity
EP1515960A4 (en) 2-THIOXOTHIAZOL DERIVATIVE, METHOD FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF
AU2003232684A8 (en) Pyrazole-3-one derivative, method for preparing the same, and pharmaceutical composition containing the same
AU2003271956A1 (en) Benzofuran derivatives, formulations and uses thereof
AU2003283508A1 (en) .pharmaceutical composition comprising htless thansbgreater than4less than/sbgreater thandless thanspgreater than100less than/spgreater thana receptors, and therapeutic uses thereof
MXPA03008636A (es) Derivados de isoquinuclidina, metodo para fabricar los mismos y agentes terapeuticos que contienen estos compuestos.
EP1338275A4 (en) Pharmaceutical composition, its use and method of making the same
HRP20070517A2 (en) Escitalopram hydrobromide and a method for the preparation thereof