TW200422046A - Skin protecting composition - Google Patents

Abstract

The present invention provides a skin protecting composition for effectively inhibiting the invention of infectious bacteria such as Pseudomonas aeruginosa, Bacillus, anthrax, Escherichia coli, Staphylococcus aureus, MRSA (Methicillin Resistant Staphylococcus Aureus), etc., and viruses such as influenza virus from mucosas of eyes, nose, throat, ear, anus, vagina, etc., as well as wounds and skin and meanwhile inhibiting their growth; a skin protecting composition for effectively preventing nosocomial infection caused by drug-resistant bacteria; a composition for preventing and/or treating of bacteria infection and viral infection including nosocomial infection; a preservative; a filter device for effectively inhibiting the invasion of infectious bacteria and viruses, and their growth. The present invention provides a skin protecting composition, which is characterized by containing short bamboo extract or short bamboo extract with organic acids as an effective component; a skin protecting composition for effectively preventing nosocomial infection caused by drug-resistant bacteria; a composition for preventing and/or treating the bacteria infection and viral infection including nosocomial infection; a preservative; a filter device for effectively inhibiting the invasion of infectious bacteria and viruses.

Description

200422046 5 long, description of the invention [Technical field to which the invention belongs] + Poverty% You have one composition against dandruff, especially b. From the eyes, nose, throat, ears, anus, genitals and other mucous membranes :: Τ is effective, and the sensation to the injured site is fine, or the virus invades the body, and it can also suppress hair straightening the skin 4 morning护 组合 物。 Composition. The invention also relates to preservatives. ^. ,, Douyue also refers to a filtering device that can effectively prevent the invasion of infectious bacteria and viruses. Fang-[Previous technology] to inhibit its proliferation-Pseudomonas aeruginosa, Bacillus subtilis, anthracnose, E.coli, golden staphylococcus search for infectious bacteria and influenza viruses and other viruses, in the "disorderly dryness", you swim, pain from the human Invasion of animal's mucous membranes or wound sites' makes humans and animals feel severely infected. Various antibiotics have been used for this kind of bacterial infections. Second, however, the results of excessive use of antibiotics' have emerged from all existing antibiotics: Ineffective resistance to various antibiotic-resistant bacteria such as the new phytoplasma aureus (Mrsa) . As a result, it is not uncommon for patients in hospitals and doctors, nurses and other resistant bacteria to sometimes cause death. On the other side, recently, in the United States, politicians and media companies have received a letter containing anthrax bacteria, 'Most of the parties opened it with unprotected status and became infected with anthrax bacteria.' panic. Therefore, not only Mak and public servants, but also the general public are facing such a situation and are anxious to have appropriate defense measures against this biochemical weapon. "[Summary of the Invention] The purpose of the present invention is to provide a skin protection composition which can effectively inhibit mucous membranes from the eyes, nose, throat, wounded parts and skin from adenophyllum aeruginosa, anus two, genitals, etc. , Staphylococcus aureus, mrsa 囷 anthracnose, E. coli, K garden] ViRSA, gas bacillus and other infectious bacteria and marks _ #, 知 风 # sleepy, botulism invades the body, Π π π & 4 "Symptoms such as susceptibility I and coronavirus can also inhibit their proliferation. Another object of the present invention is to provide a skin protection composition that can effectively prevent the introduction of Shikiji Temple due to resistant bacteria. Other objects of the present invention are to provide information on the bacterial susceptibility of nosocomial infections in the hospital, and the ninety-eight types of nosocomial infections and the composition for the prevention and / or treatment of disease-free infections. Yet another object this month is to provide a preservative. In February, another object was to provide a filter device that can effectively inhibit infectious bacterial diseases and also inhibit its proliferation. The present invention provides the following skin protection compositions; compositions for the prevention and treatment of bacterial and viral infections; preservatives and agents. ~ 1. Skin protection composition with 3 dwarf bamboo extracts as active ingredients. 2 · A composition for the prevention and / or treatment of bacterial infections using s short bamboo shoots as an active ingredient. 3. A composition for the prevention and / or treatment of viral infections containing dwarf bamboo extract as an active ingredient. 4. Composition for preventing and / or treating nosocomial infections containing dwarf bamboo extract as an active ingredient. Either composition is in the form of an oral composition 5. As above! A composition according to any one of 4 to 4, which further contains an organic acid. 6. As above 1 to Canton > μ ........., ▲ a ^, ,,, · 8 314612R] 200422046. 7. The composition as described in 6 above, which are sweets, jams, smoothies, milk lin, rentang, jelly, lozenges, candy, rice crackers and other cakes, bread, Biscuits' chocolate, mouthwash, mouthwash, teether λ & ★, drink water, bonding agent, granules, washing state. …, 4 films, spray form for throat inflammation treatment 8. Shikou The above 1 5 5 y-n to any one of the group 9 9. The composition according to 8 above, which is in the form of gauze, = guarantor, etc. Sanitary napkins, bandages, toilet paper, diatoms, physiology belts, insoles, ears. ^ Earth hemorrhoid gauze, horse pain seat paper, military soil ear base, gloves, hats, lab coat curtains, wall moths, Envy ^ Broken cover, pillowcase,,,,, %%, surgical suture form. 1 〇. The composition according to the above 8 is in the form of gauze. 1 1 · A mask containing gauze as described above. 12. A preservative containing pound bamboo extract as an active ingredient. 13 · The preservative according to 12 above, which contains organic acid as an active ingredient. 14. Filtering device containing edible bamboo extract as an active ingredient. 1 5 · The filter device according to 14 above, which contains organic acid as an active ingredient. 16. The filter device as described in 14 or 15 above, which is in the form of a filter used in the air passing part of a range hood, air conditioner, air intake η, air discharge port, screen window, air cleaner, vacuum cleaner, etc. 1 7 · An air cleaner including any of the above-mentioned filtering devices of 1.4 to 16. [Embodiment] The present invention will be described in detail as follows: 逄 竹 9 314612R] 料 0 料 0 The text is effective for the present invention and is specially cited _ 屌 I 屌 dwarf bamboo, can be widely produced 'as an example: belongs to dwarf bamboo All of the genus (SaSa). σ column + such as: bear bamboo, limit bamboo, thousand island bamboo wild soap small "^ dry island bamboo A mangosteen, Mengzong bamboo m, dwarf bamboo, deep mangosteen, sendai bamboo, tangchuan bamboo, abo bamboo, small nok bamboo, etc. Specific examples of the sale items can be mentioned: can (Chinese bamboo, Feiyi bamboo, Xi Xiqi π here *, ', bamboo ^ bamboo fantasy search ten extracts. For example, collected in October in the Tianyan Mountains in Hokkaido Water extracts of bear bamboo and osmanthus are preferred. The dwarf bamboo extract used by Ben Moming is raw bamboo leaves or dried leaves. It is best to dry dried dogwood to i8 (rc water The method of extraction is not limited, but the method disclosed in, for example, Japanese Patent No. 3212278 (Japanese Unexamined Patent Publication No. u_1968-18) can be used. More specifically, A pressurized hot water extractor is used to extract 5 to 30 knives and 4 strokes at 100 to 18.0. The extract is separated into a water-containing solid component by a water separator (a water content of 40 to 7). %) 'Then, the water-containing solid component is treated at 1G0 to 0 ° C with a saturated steam heating processor, and then added to The hot water extractor is processed under the conditions of 〇〇 ～} 80 for 5 to 30 minutes to extract the extracts' and combine the first and second extracts. It is also possible to use, for example, dried bamboo leaves at 60 to 100t of water °, extract from about 2 minutes to 2 hours. The extract containing 50 masses of solid bamboo stock is commercially available as "AHSS manufactured by Kuroshima Mosiri". The dwarf bamboo extract contains sulphur, which is converted into sulphur. The solid content of dwarf bamboo extract contains 1 gram and contains about 4 to 10 mg, 10 314612R1 200422046 amine group, spoon is 6 to 9mg. The main component of the salty carbon yellow component is sulfur-containing composition. The composition is derived from dwarf bamboo extract and converted into thioprene knife. The amount of 1008 contains 4 to 500mg. And it is more preferable to be 25 mg, and it is most preferable that it contains 16 to 1501%. It also contains a dwarf bamboo extract system, which contains tannin, and its content and body composition is about 5 to 15% by mass. The composition of the present invention is expected to contain thick shoulders of dwarf bamboo tannin to solid content, preferably from 0.05 to 7.5% by mass, and from 0 ·! To 6% by mass. Even better, the composition of the present invention can only use the dwarf bamboo extract as an active ingredient, and the use of the same with an appropriate amount of organic acid can further improve its treatment and / or pre :: effect. Such organic acids can be Examples include: malic acid, citric acid, lactic acid, acid, malonic acid, succinic acid, fumaric acid, acetic acid, benzoic acid, phenylacetic acid, salicylic acid, g classification, etc. In the composition of the present invention, The amount of organic acid used is preferably from 0.01 to 5 minus $%, especially j; 乂 η η ο z ;, & especially 〇02. To] quality ❶ is better, and 0.05% to 1.5% is the best. ~ Including ... Compositions for prevention and / or treatment of skin, skin and skin composition, bacterial infection, and virus infection prevention and / or treatment composition system in this month can effectively inhibit from the eyes, nose, Infectious bacteria in mucous membranes and wound sites such as throat, ear and anus, genitals, and skin, and skin: poison invades the body, and effectively prevents and / or treats infections including nosocomial infections, sassafras, and influenza virus, herpes virus, corona Viral infections such as viruses]) 314612R] 200422046 For example, the skin and skin protection wool and other natural acrylonitrile-based fibers are mixed with paper, etc. The skin protection composition with the "protection etc. as the active ingredient" in the dipping book is used for the prevention and / or treatment of poisonous infections. The form of the material can protect the cloth and oral composition. The protective cloth is on a breathable carrier, such as silk, cotton, linen, and fiber; polyurethane, vinylon, polypropylene, nylon, polypropylene, and synthetic fibers; semi-synthetic fiber or two or more of these : Those who are impregnated with dwarf bamboo extract by methods such as dimensional or yarn or weaving, weaving, non-fibre cloth, two, mouth mist, etc. In this description, '^ cloth j, in addition to cloth, also includes the fiber itself, thread, and paper management tape? ::: Sadness: For example: & categories are gauze, masks, eye masks, tissue paper, leather, sanitary 'paper, gauze for itching sores, direct contact with earplugs, waterproof tape and other sanitation Supplies 'Beyond mucous membranes, skin hats, socks + protective cloth', there are also experimental clothing and other clothing, gloves, bed covers ... / new cloth socks, linens, quilts, pillow cases, decoration materials, K 7 Upholstery such as furniture, curtains, wallpaper, carpets, etc. and medical materials such as surgical sutures, etc. directly or indirectly come into contact with the cooking utensils such as cutting boards. The person of the present invention ^ The oral composition of sugar and bamboo extract can be exemplified by: soft bundles, bran tablets, peach fields, etc., beverage water, bud sugar, cake, / tang fruit, chewing gum, jam, ice Sand, cream, barley, etc ...: biscuits, chocolates, rice crackers and other pastries, breads, noodles, granules, mouthwash, cough, toothpaste, sticking film, mouth mist for throat inflammation treatment 314612R1 12 200422046 Impregnate the bamboo shoot extract in a skin protective cloth, for example, dip the protective cloth in an aqueous solution of bamboo shoot extract of 2 to 20% by mass, or an aqueous solution of bamboo shoot extract of 2 to 20% by mass Spray on the protective cloth and dry it. On this day, the dipping or slump of the bamboo extracts: £ 'The solid content of the bamboo extract is preferably 2 to 20% by mass, and 6 to 1 5 Quality is better, 8 to 12 quality is better. Up and down is the best. When less than 2% by mass, the effect of the purpose of expression is insufficient, and when more than 20% by mass, the skin or mucous membrane has a tingling sensation, and the effect is The skin protection composition of the present invention will be derived from the dwarf bamboo extract. The yellow component is converted into sulphur yellow, and the average per 100 g of the protective composition contains 8 to 200 mg of sulfur kappa, more preferably 24 to 150 mg, and most preferably 32 to 120 mg. Examples of containing dwarf bamboo extract: soft candy , Jelly, lozenges, candy, chewing gum, jam, smoothies, cream, maltose, cakes, biscuits, chocolate, rice crackers and other pastries, breads, noodles, beverage water, lozenges, pills (e.g. ), Oral compositions such as mouthwash, tincture, toothpaste, plaster, etc. are at any stage of the manufacture of oral compositions, and the solid content of the original oral composition is appropriately added to the dwarf bamboo extract to 2 to 2 〇 Mass% is better, 6 to 15% by mass is more preferred, and 8% to 12% by mass is the best. When it is less than 2% by mass, the effect of performance purpose is insufficient, and it exceeds 20%. When the skin or mucous membrane has a tingling sensation, and the effect cannot be further enhanced and is not in line with the benefits. The bamboo dwarf bamboo extract is impregnated with a protective cloth or oral composition or after impregnation. It is best to be 70 to 9 (rc (to 75 to better), add 314612R1 200422046 heat treatment for 30 minutes to 3 hours Time (from} to _ and more forceful + + _, is 1 soil). Jingli treatment ruler plus Lingsheng skin protection effect. · ,,, and ingredients in the oral composition of the present invention. Examples & amp ... Can be formulated according to the type of appropriate knife J. For example: ® glucose, cut sowing, dextrose cyclodextrin eye-catching f 1 'sugar, maltose, dextrin, tsukisuji temple excipients, Gum arabic, vitamin table / ^ methyl mechanical vicinol, 4 Shiyue miscellaneous, Junbu, gum matrix and other adhesives, jealousy, sodium, sodium, sodium, fatty acids, and other lubricants, spices , Chlorophyll, diazepam, etc., and the skin protection composition of the present invention, such as menthol, etc. When the product is used in the form of a thin cloth, the contact of the beta film or wound site is guaranteed for 1 s. The cloth (々 布 寺) is impregnated with dwarf bamboo extract. When changing the girl 1 to 3 times a day, you can right Γ. Use in the form of surgical sutures to promote the introduction of π A and suppress inflammation in the affected area, and then delay the recovery of the surgical site. In order to prevent nosocomial infections in hospitals, etc., it can be used in the shape of a protective cloth. 反 反 44 ～ Composition The structure of the skin protection composition of the present invention can be long ^ α wood prevention effect. When the effect is reduced due to washing, it can be replaced by δ or re-treated with impregnated dwarf bamboo extract. The skin protection composition of the present invention is used in the form of an oral composition, and its ingestion is not particularly limited. It is a solid ingestion of dwarf bamboo extract, and the portion is about 2 to 15] Qiu Zm, and Nmg, for example I to 5 times a day, usually about 1 to 3. Ingestion p 彳 # to take li, the number of intakes can be increased or decreased moderately according to the purpose. 2. The solid content of the dwarf bamboo extract impregnated with the skin protection composition of Ben Sheming is 2 to 20% by mass, and it has a significant bactericidal effect on resistant bacteria that have always been ineffective with antibiotics. 3146J2R] 14 200422046 In addition, the skin protection composition of the present invention is used as an oral composition. If appropriate and necessary, it can be contained in the mouth to prevent the infection of infectious bacteria or viruses, and inhibit the infection. The composition of the progressive form of chewing gum and candy temple can exert its long-term effect and is advantageous. … The skin protection composition of the present invention can also be used in ointments, creams, jelly gels, gels, emulsions, oils, and soaps. The solid ingredients containing dwarf bamboo extract are 2 to 2 〇 KING Berry / π dry words, creams, gels, gels, emulsions and oils (such as ... Ba oil, grape seed oil, spear and germ oil) painted right ^: & teeth by) soil cloth in the skin temple 'can prevent infection of infectious bacteria and viruses very easily, and can inhibit its proliferation. The present invention also provides a preservative containing dwarf bamboo extract as an effective ingredient. There are no restrictions on the form of the preservative. Examples of ingredients that can be used as preservatives are: mouthpiece ^, .. < ° σ, drink water, seasoning, cosmetics (including lotion and oil), base name 丨 ° treatment] ^ ° spray for position Aerosols and vets for throat inflammation. The solid content of the dwarf bamboo extract of the object of the temple 〇Λ ^ for the temple object is preferably 2 to 20% by weight, and 6 to 5 pounds! % Better, from 8 to 12% by mass

Right attack. If less than 2 quality I Bailey / 0 day guard, the purpose of the anticorrosive effect presented is insufficient, and if more than 20 quality 詈 〇 / Λ 祌 ^, T 'can not enhance its effect and is not consistent with the benefits, such as adding to food At this time, it is not ideal that the σ _ gengut is not forced to change. Seeing ^ n Ming also provides empty concrete forms containing dwarf bamboo extract as an active ingredient, such as: range hoods, air conditioners, car air conditioners, milk intakes, air exhausts, screens, air cleaners, vacuum cleaners, etc.] 5 314612R] 200422046 The filter used in the random passage part. Filters can be wrapped without any shaking | No restrictions, such as natural polypropylene bridges such as silk, cotton, wool, linen, etc., " 隹, polyamine si fiber, nylon, polyester, acrylonitrile fiber, Nakatoyo Yaki fiber, synthetic fibers such as 隹 nylon, 卞 D into dimensional, glass fiber, or these two types of fiber cloth with a combination of right and left, water release, &, y The dilute lutetium I mixture is impregnated, sprayed, etc. and then dried ^. Yttrium ^ wood. The solid content of the dwarf bamboo scoops in the strainer is preferably 2 to 20% by mass. Bamboo mass% Chengduberry / 0 is preferred, 4 to 15% 0 ±, and 2 to 6% by mass is most appropriate. Less than 2 masses. / * Shuangguoya is inadequate, and when it ’s over Π ’, it ca n’t improve its effect and is not in line with efficiency. Presence—Part: The bacteria and viruses in the item are captured by the filter, and the bacteria and viruses can be prevented on the filter by filtering or inhibiting their proliferation. The reference examples shown below, Examples and test examples can explain the present invention in more detail, but are not limited to these examples *, and will not be described here. The "%" in this manual is calculated as "mass%" unless otherwise stated. Reference example 1: Production of dwarf bamboo extract β 舲 The dried leaves of bear bamboo collected on September 9 in Morioka, Hokkaido, were put into a pressurized hot water extraction bucket, treated with 125t: 10 minutes, and heated with cooling water. The water was cooled to about 801, and the extract and the water-containing solid component were separated by a screw press so that the water content became about 50% by mass. Next, about 50% by mass of the water-containing solid content was placed in an autoclave, and a saturated water vapor pressure heat treatment was performed at i800C for 10 minutes. Put the treated water-containing solids into the pressurized hot water extraction bucket again. 1 (5 minutes under rc extraction, extract dwarf bamboo extract 314612R1 200422046 extract and combine the first and second extracts and filter through diatomaceous earth to reduce the solid content to 50% by mass, and then The dwarf bamboo extract was obtained by flowing sterilization treatment from 1 10 to 30.0. 4 The content of sulfur in the extract of dwarf bamboo was 3 85〇 # solid content 1 g 丨. Reference example 2 ·· Contains organic acid Extract of dwarf bamboo extract In the dwarf bamboo extract (solid content: 50% by mass), 0.5 g, 1 g, 5 g, or 2 g of malic acid was added to the dwarf bamboo extract produced in McCau Example 1. Example 1: Manufacture of chewing gum In 100 g of gum base heated at 6 (TC for 30 minutes) in a constant temperature bath, add the dwarf bamboo extract (solid content, 50% by mass) ) 2 to 15S, simmer for 2 minutes and then warm at rc (10 minutes. The resulting smelt is left to cool and then rolled into a sheet with a thickness of about 1 ·. Type chewing gum). Example 2: Production of granules ^ Blend the following composition (unit: mass%) with a kneader, and then use this to granulate Producing molding granules. 21 ·· of dwarf bamboo extract (solid content 50% by mass) 10 2〇 licorice cinnamon mint 5 15 15 Thyme anise ginger cloves 314612R1 200422046 t 5 8 2 Γοο

• Tushangshan • Maize Stirring: Powder. Rhenium oxide'rWn Example 3: Protecting gauze extract of dwarf bamboo (solid sprayed, 80% 8 · 8 mass% of dwarf bamboo is extracted on silk gauze, for reference Example 丨 Manufacturing ingredient 50% by mass) Liquid diluted with 10 times water #

Dry for 1 hour to make a protective gauze impregnated with solid ingredients ^. Page relaxation example 4: One gauze is retained. The silk gauze is manufactured in the mass% of reference example 2.) The liquid diluted with 6 times water (solid content is evaluated into moon beans, at 800 ° C, The master dries again for 1 hour, 1 hour, 1 hour, 3 hours of clothing, 3 forks, and a protective gauze of dwarf bamboo extract. ^ The knife is 8 meters. Example 5: Protective mask. Insert the protective gauze of Example 3 or 4 Protective masks are made from the inside of the mask. Example 6 made of y, y cloth: Air purifier Place the filter used by the general air purifier on the bamboo extract (50% by mass of solid content) at 6 times Manufactured by grabbing dipped in grabbing! Hours, and then dried up _ money = sifter with 8% by mass of bamboo extract. The air purifier will be cleaned. 4 rounds of female melon 1 : Antibacterial test 3] 46] 2R] 18 200422046 Prepare the protective gauze for the garment of Example 3 (containing the solid content of dwarf bamboo extract 8.8 mass.) And silk gauze without dwarf bamboo extract (control) ^ Cloth). On each gauze (5x 7cm), drop the following bacterial solution (the number of bacteria is about 5 104 / or or about 5.0 × 105 / ml) lm in the incubator It was left to rest for 3 hours in 3 generations. After the culture was completed, the gauze was filled with a knife and washed with 10 ml of liquid, 10 months of oral violence, and made into a test solution. The brain heart leaching solution agar ^ ^ from dried wood Spread the 2nd solution on a ten-plate culture medium in a spiral system (NASA system 'USA). Incubate in an egg incubator for 18 hours. Calculate the number of colonies on the soil of brain heart leachate agar plate. The results are shown in Tables 1 and 2. Table 1

The number of bacteria in TJ was 314612R] 19 200422046, which was reduced to about 丨 / ^ ⑼ to 1/10000 ’. The number of bacteria in gauze without dwarf bamboo extract increased by about ⑽ times. This line shows that the gauze cloth containing dwarf bamboo extract of the present invention has excellent antibacterial properties, especially the resistant bacteria MRSA which is also ineffective against antibiotics. Test Example 2: Anti-proliferation test of anthracnose 1. Test method:

Strain: Anthracnose 34-F2 (weak strain that produces toxins and does not form capsules). It is formulated to use about 34,000 per 0.1 ml. Test solution ·· 50% by mass of solid content of bamboo extract Extraction method: Dilute the test solution with sterilized distilled water, and mix with 25 / 〇, 12.5%, 6.25%, 3.2%, and so on! For 6%, 0.8%, and 0.4% liquids, perform the following two inspections. Use sterilized distilled water as the control solution. (1) Mix the spores of anthracnose 34-F2 0.1ml into each of the 10 kinds of 50 to 0% of the test solution prepared above, leave it at 37t for 24 hours, and then apply this 0.1ml to the brain heart Leachate (BΗIρ4 vegetable medium, 37 ° C '24 hours of cultivation, observe the colony development. This = Temple also observe the increase and decrease in the number of bacteria in sterilized distilled water. (2) 10 kinds of 5 prepared above To 0% of the test solution, 10% of Bm agar was added to the test solution to make a plate of agar. The spores of the anthracnose 34-F2 were coated on each medium with a thickness of 01m and cultured at 37cc. Observe the colony development. Only 2 · Results: The results are shown in Table 3 below. 314612R1 20 200422046

3. Conclusion:-Although the bactericidal effect of the tested dwarf bamboo extract on the anthracnose sprouts could not be determined, it can strongly inhibit the proliferation of anthracnose. The result is that the skin protection composition of the present invention containing a dwarf bamboo extract can suppress the proliferation of anthracnose, and as a result, can prevent an infection caused by anthrax. Stupid example 3 · Test of antiviral effect against influenza virus 1. Test method: The virus uses herpes simplex virus (HSV) HF strain, herpes simplex virus (HSV) UW strain, influenza virus (Inf) A / pR / 8 For strains and influenza virus lines, (Inf.) A / FM / 1/47 g strain was used. The feeder cells were made of tadpole cells (from the kidneys of African green apes) and inf • mdck cells (from dog kidneys). The antiviral effect is the virus solution 1 () // 1 and the reference example! The prepared dwarf bamboo extract was diluted with sterilized distilled water and taken lm] and mixed, and inoculated the hearts in M micro-well disks] Strain-shaped cells cultured at room temperature (23 ± 3t), 6 Haipanfang; j 7 The degree of cell degeneration effect (CPE, Cytopathologica] effect when cultured under a carbon monoxide incubator at C was determined according to the following criteria. The control group used distilled water (DW). NT · No 5 test, 4+ · Micropores are all C] pE, ·· More than μ% of micropores are CPE, 2+: cpE to 75% of micropores, +: 25 of micropores 314612R1 200422046 Observation Do not

CPE up to 50%, CPE up to 25% of the micropores. CPE to CPE Electron microscope sample system The cultured fine moon pack is treated with virus sensation ^ 20 hours and diluted with bamboo extract extracted, and solidified according to the method ^ ,Observed. 2. Results ... Single, single, herpes simplex virus (HS V) HF strain, herpes simplex virus (HS v) uw strain, influenza virus (Inf.) A / PR / 8 strain, influenza virus strain pair (Inf. The antiviral effects of A / FM / l / 47 strains are shown in Tables 4 to 7. Table 4 HSV HF strains ____Solid composition of P. chinensis extract 10 8 5 3 2 1 Steamed water 1 min 3 + 4 + 4 + 4 + 4 + 4 + 4 + 5 points ~-soil 4 + 4 + 4 + 4 + 4 + 10 points one-~ 2 + 4 + 4 + 4 + 15 points one one-home soil 2 + 4 + 30 minutes — one — — one 4 + 60 minutes — — one — — 4 + The virus was inactivated by treatment at 10% concentration for 5 minutes, and inactivated by treatment at 1% concentration for 1 hour. Table 5 HSV UW Strain Dwarf Bamboo Extract Solid Content (%) 10 8 5 3 2 1 Distilled Water 1 minute — ± 2 + 2 + L -—--------- 3 + 4 + 4 + 5 points — — 1 + soil 2 + 3 + ------4 + 10 points----B ------- Shitu 4 + 15 points one--------- one-4 + 30 points — One — one one — 4 + 60 minutes — one one one — — — — — 4 + 22 314612R1 200422046 The virus was treated at 1 ()% concentration for 1 minute to inactivate it. 1% concentration may also be treated for 15 minutes inactivated. And Table 6 Inf · A / PR / 8 strain

Virus strains were inactivated at concentrations above 0.5% for 30 minutes Table 7 Inf · A / PR / 47 strains

From this result, it is clear that the anti-hernia effect of dwarf bamboo extract ^ on influenza virus is different from that of existing preparations, but the mechanism of action of j: bamboo 'eight is not clear. 314612R1 23

Claims (1)

200422046 The scope of patent application: i • A skin protection composition containing dwarf bamboo extract as an active ingredient. 2. A new product for the prevention and / or treatment of bacterial infections, containing dwarf bamboo extract as an active ingredient. A 3 · -type composition for the prevention and / or treatment of filtered pathogen infection, in which bamboo extract is an effective ingredient. S pound 4.-A composition for the prevention and / or treatment of nosocomial infections in the seed. Zhu Zu 5. If any of the scope of application for patent application 丨 4 _ Those who contain organic acids. The composition of the member is another 6. The morphology of the oral composition as described in any one of ^ 5 of the scope of patent application. $ 7. For the composition of item 6 in the scope of patent application, sugar lozenges, candy, chewing gum, jam, smoothies, milk sugar, sugar, sugar, pastry, bread, etc. , Drink water, bonding agent, granules, mouthwash # ', face address, human agent, dental floss, "", spray form for the treatment of throat inflammation. Posts 8 · If the scope of patent application 1 1 Those who are in the form of any one of the 5 items. The material is the composition of item 8 in the scope of the patent application, which is gauze, physiological bands, sanitary cotton, bandage eyes, toilet seat paper, shoe last, Earplugs, gloves,, >, sheets, quilt covers, # 商 子 一 & 子, clothing, food items, pillowcases, curtains, wallpaper, ground pattern. ', Surgical seam 3l46l2R] 24 200422046 1 ο. For example, if you apply for a patent, the composition of item 8 of pure encirclement is the form of gauze. 1 1 · A mask, the person ^ contains the gauze of item 10 of the scope of patent application. 1 2 ·-anti-corrosion Agent 3 dwarf bamboo extract is an effective ingredient. 1 3 · If the scope of patent application is W 12 Agent, whose active ingredient contains another organic acid. 14. A filter device containing dwarf bamboo extract 1 5 · If the scope of patent application i 4 contains organic acid. 1 6. If the scope of patent application 1 # bite tobacco The effective components of the filter device of item 1, its effective component is the filter device of the other 5 items, which are connected to the air vent, f exhaust port, screen window, air of the oil purifier, vacuum cleaner, etc. —A kind of air cleaner, which is in the form of a filter with the right t part. Any one of the transitional devices. The scope of application for the patent is 14 to 16314612R1 25 200422046 / 柒, the designated representative picture ·· There is no picture in this case Formula (1) The designated representative figure in this case is: (). (2) Brief description of the element representative symbols of this representative figure: 捌 If there is a chemical formula in this case, please reveal the chemical formula that can best show the characteristics of the invention: 314612R] Skin protection composition SKIN PROTECTING COMPOSITION 贰, Applicant: (1 person in total) Name or name · (Chinese / English) Phoenix Church Co., Ltd. / H0U0UD0U CO., LTD. Representative: (Chinese / English) Doda Yuzo / YUUZOU TSUCHIDA Address of residence or business office: (Chinese / English) 3-2, 3-2, Ebara 4-Chome, Shinagawa-Ku, Tokyo, Japan, Ebara 4-Chome, Shinagawa-ku, Tokyo, Japan Country: (Chinese / English) Country / JAPAN Participants and inventors: (Total 6 persons) Name: (Chinese / English) Tsuchida Yusan / YUUZOU TSUCHIDA Tsuchida Kotarou / KOTAROU TSUCHIDA Tsuchida Kenjiro / KENJIROU TSUCHIDA Address: (Chinese / English) 1 · 2. 3 · Koyama 4-Chome, Shinagawa-Ku, Tokyo, Japan 15-7, Koyama 4-Chome, Shinagawa-ku, Tokyo, Japan Nationality: (Chinese / English) Japanese Country / JAPAN Name: (Chinese / English) Watanabe友 / KUNITOMO WATANABE 314612R1 200422046. Table &9; Address of residence: (Chinese / English) 3-62-3, # 2, Fansan-cho, Gifu-shi, Gifu, Gifu-Shi, Gifu-Shi, Gifu , Japan Nationality ·· (Chinese / English) Japan / JAPAN Name: (Chinese / English) Ryoko Nakamura / Y0SHIK0 NAKAMURA Address: (Chinese / English) 5_11-1 Furubuchi, Sagamihara, Kanagawa Prefecture, Japan , Kobuchi, Saganiihara-Shi, Kanagawa, Japan Nationality: (Chinese / English) Japanese Country / JAPAN Name ·· (Chinese / English) Iwasawa Atsuro (Iwata Atsuro) / ATSU0 IWASAWA Residence Address: (Chinese / English) Said Kanagawa 24-1-210 Umeoka, Aoba-ku, Yokohama-shi, Prefecture 24-1-1210, Umegaoka, Aoba-Ku, Yokohama-Shi, Kanagawa, Japan Nationality · (Chinese / English) Japanese Country / JAPAN 2 314612R1