TR201910900T4 - Desferritiyokin polieter analogları. - Google Patents
Desferritiyokin polieter analogları. Download PDFInfo
- Publication number
- TR201910900T4 TR201910900T4 TR2019/10900T TR201910900T TR201910900T4 TR 201910900 T4 TR201910900 T4 TR 201910900T4 TR 2019/10900 T TR2019/10900 T TR 2019/10900T TR 201910900 T TR201910900 T TR 201910900T TR 201910900 T4 TR201910900 T4 TR 201910900T4
- Authority
- TR
- Turkey
- Prior art keywords
- desferritiokine
- polyether analogs
- analogs
- polyether
- neoplastic
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/04—Chelating agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/10—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Obesity (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66804505P | 2005-04-04 | 2005-04-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR201910900T4 true TR201910900T4 (tr) | 2019-08-21 |
Family
ID=36676582
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2019/10900T TR201910900T4 (tr) | 2005-04-04 | 2006-03-22 | Desferritiyokin polieter analogları. |
Country Status (14)
| Country | Link |
|---|---|
| US (6) | US8278458B2 (https=) |
| EP (2) | EP3190106B1 (https=) |
| JP (3) | JP5202299B2 (https=) |
| CN (1) | CN101189216B (https=) |
| AU (1) | AU2006232929B9 (https=) |
| BR (1) | BRPI0610644B8 (https=) |
| CA (1) | CA2603385C (https=) |
| CY (1) | CY1119002T1 (https=) |
| DK (2) | DK3190106T3 (https=) |
| ES (2) | ES2732625T3 (https=) |
| MX (1) | MX2007012226A (https=) |
| PL (2) | PL3190106T3 (https=) |
| TR (1) | TR201910900T4 (https=) |
| WO (1) | WO2006107626A1 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6083966A (en) | 1998-08-31 | 2000-07-04 | University Of Florida | Thiazoline acid derivatives |
| WO2005034949A1 (en) | 2003-09-09 | 2005-04-21 | University Of Florida | Desferrithiocin derivatives and their use as iron chelators |
| BRPI0610644B8 (pt) | 2005-04-04 | 2021-05-25 | Univ Florida | composto e composição farmacêutica que compreende tal composto e um veículo ou diluente farmaceuticamente aceitável. |
| US20100137346A1 (en) * | 2006-12-12 | 2010-06-03 | University Of Florida Research Foundation, Inc. | Desferrithiocin analogue actinide decorporation agents |
| JP5439193B2 (ja) * | 2007-03-15 | 2014-03-12 | ユニバーシティー オブ フロリダ リサーチ ファンデーション, インク. | デスフェリチオシンポリエーテル類似体 |
| US8063227B2 (en) * | 2008-07-14 | 2011-11-22 | Ferrokin Biosciences, Inc. | Salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents |
| BR112012001761A2 (pt) * | 2009-07-27 | 2017-05-09 | Ferrokin Bioscience Inc | composto de formula i, composto farmacêutica e método de tratamento de uma condição mediada por metal em um indivduo |
| US20120184586A1 (en) * | 2009-08-25 | 2012-07-19 | University Of Florida Research Foundation, Inc. | Desferrithiocin polyether analogues and uses thereof |
| US9045440B2 (en) | 2010-05-04 | 2015-06-02 | Ferrokin Biosciences, Inc. | Desazadesferrothiocin and desazadesferrothiocin polyether analogues as metal chelation agents |
| TW201338777A (zh) | 2011-12-09 | 2013-10-01 | Ferrokin Biosciences Inc | 用於治療金屬過載之經口調配物 |
| JP6539046B2 (ja) * | 2011-12-16 | 2019-07-03 | ユニバーシティー オブ フロリダ リサーチ ファンデーション, インク. | 4’−デスフェリチオシン類似体の使用 |
| EP2970162A1 (en) | 2013-03-15 | 2016-01-20 | Ferrokin Biosciences, Inc. | Polymorph forms of desazadesferrithiocin analogs |
| CA2930966A1 (en) * | 2013-11-22 | 2015-05-28 | University Of Florida Research Foundation, Inc. | Desferrithiocin analogs and uses thereof |
| SG11201610906XA (en) * | 2014-07-18 | 2017-02-27 | Applied Materials Inc | Additive manufacturing with laser and plasma |
| EP3288557A4 (en) * | 2015-04-27 | 2018-11-07 | University of Florida Research Foundation, Inc. | Metabolically programmed metal chelators and uses thereof |
| US10982136B2 (en) | 2016-02-26 | 2021-04-20 | The Regents Of The University Of California | Ligand-sensitized lanthanide nanocrystals as ultraviolet downconverters |
| KR20230004944A (ko) | 2016-08-05 | 2023-01-06 | 아브페로 파마슈티칼스, 인크. | 금속-매개 상태를 치료하기 위한 투여 요법 |
| EP3503930B1 (en) | 2016-08-29 | 2024-12-11 | Fred Hutchinson Cancer Center | Chelating platform for delivery of radionuclides |
| JP7018210B2 (ja) | 2016-09-06 | 2022-02-10 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | ヒドロキシピリドネートアクチニド/ランタニド体外除去剤の製剤 |
| CA3038670A1 (en) | 2016-09-29 | 2018-04-05 | The Regents Of The University Of California | Chelating molecules |
| EP3520117B1 (en) | 2016-09-29 | 2023-11-08 | The Regents of The University of California | Separation of metal ions by liquid-liquid extraction |
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| JP2007505044A (ja) | 2003-09-09 | 2007-03-08 | ユニバーシティ オブ フロリダ リサーチ ファウンデイション、インコーポレイテッド | ポリアミン−金属キレーター接合体 |
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| BRPI0610644B8 (pt) | 2005-04-04 | 2021-05-25 | Univ Florida | composto e composição farmacêutica que compreende tal composto e um veículo ou diluente farmaceuticamente aceitável. |
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| US20100137346A1 (en) * | 2006-12-12 | 2010-06-03 | University Of Florida Research Foundation, Inc. | Desferrithiocin analogue actinide decorporation agents |
| JP5439193B2 (ja) | 2007-03-15 | 2014-03-12 | ユニバーシティー オブ フロリダ リサーチ ファンデーション, インク. | デスフェリチオシンポリエーテル類似体 |
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| US8063227B2 (en) | 2008-07-14 | 2011-11-22 | Ferrokin Biosciences, Inc. | Salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents |
| PL385765A1 (pl) | 2008-07-28 | 2010-02-01 | Maciej Żurek | Sposób sterowania łopatą napędową względem kierunku wiatru, zwłaszcza w silniku wiatrowym i wodnym o osi prostopadłej do kierunku wiatru oraz silnik wiatrowy o osi prostopadłej do kierunku wiatru z łopatą napędową sterowaną względem kierunku wiatru |
| BR112012001761A2 (pt) | 2009-07-27 | 2017-05-09 | Ferrokin Bioscience Inc | composto de formula i, composto farmacêutica e método de tratamento de uma condição mediada por metal em um indivduo |
| US20120184586A1 (en) | 2009-08-25 | 2012-07-19 | University Of Florida Research Foundation, Inc. | Desferrithiocin polyether analogues and uses thereof |
| US9045440B2 (en) | 2010-05-04 | 2015-06-02 | Ferrokin Biosciences, Inc. | Desazadesferrothiocin and desazadesferrothiocin polyether analogues as metal chelation agents |
| WO2012027794A2 (en) | 2010-09-01 | 2012-03-08 | The Mental Health Research Institute Of Victoria | Method of treatment and agents useful for same |
| JP6539046B2 (ja) | 2011-12-16 | 2019-07-03 | ユニバーシティー オブ フロリダ リサーチ ファンデーション, インク. | 4’−デスフェリチオシン類似体の使用 |
| US20140323534A1 (en) | 2011-12-16 | 2014-10-30 | University Of Florida Research Foundation, Inc. | Uses of 3'-desferrithiocin analogs |
| WO2014134701A1 (en) | 2013-03-07 | 2014-09-12 | Kane Biotech Inc. | Antimicrobial-antibiofilm compositions and methods of use thereof |
| CA2930966A1 (en) | 2013-11-22 | 2015-05-28 | University Of Florida Research Foundation, Inc. | Desferrithiocin analogs and uses thereof |
-
2006
- 2006-03-22 BR BRPI0610644A patent/BRPI0610644B8/pt not_active IP Right Cessation
- 2006-03-22 AU AU2006232929A patent/AU2006232929B9/en not_active Ceased
- 2006-03-22 WO PCT/US2006/010945 patent/WO2006107626A1/en not_active Ceased
- 2006-03-22 JP JP2008505360A patent/JP5202299B2/ja not_active Expired - Fee Related
- 2006-03-22 CN CN2006800198675A patent/CN101189216B/zh not_active Expired - Fee Related
- 2006-03-22 DK DK16196408.5T patent/DK3190106T3/da active
- 2006-03-22 MX MX2007012226A patent/MX2007012226A/es active IP Right Grant
- 2006-03-22 PL PL16196408T patent/PL3190106T3/pl unknown
- 2006-03-22 EP EP16196408.5A patent/EP3190106B1/en not_active Expired - Lifetime
- 2006-03-22 ES ES16196408T patent/ES2732625T3/es not_active Expired - Lifetime
- 2006-03-22 ES ES06739627.5T patent/ES2614086T3/es not_active Expired - Lifetime
- 2006-03-22 CA CA2603385A patent/CA2603385C/en not_active Expired - Fee Related
- 2006-03-22 PL PL06739627T patent/PL1866296T3/pl unknown
- 2006-03-22 EP EP06739627.5A patent/EP1866296B1/en not_active Expired - Lifetime
- 2006-03-22 TR TR2019/10900T patent/TR201910900T4/tr unknown
- 2006-03-22 DK DK06739627.5T patent/DK1866296T3/en active
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2007
- 2007-10-04 US US11/973,001 patent/US8278458B2/en active Active
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2012
- 2012-02-28 JP JP2012041370A patent/JP5771546B2/ja not_active Expired - Fee Related
- 2012-09-28 US US13/631,025 patent/US8722899B2/en not_active Expired - Lifetime
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2014
- 2014-04-29 US US14/264,959 patent/US9096553B2/en not_active Expired - Lifetime
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2015
- 2015-04-06 JP JP2015077336A patent/JP6178816B2/ja not_active Expired - Fee Related
- 2015-07-28 US US14/811,598 patent/US9567309B2/en not_active Expired - Fee Related
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2017
- 2017-01-31 CY CY20171100135T patent/CY1119002T1/el unknown
- 2017-02-09 US US15/428,232 patent/US9994535B2/en not_active Expired - Lifetime
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2018
- 2018-06-11 US US16/005,483 patent/US20180290990A1/en not_active Abandoned
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