ATE80801T1 - Antitumorzusammensetzungen enthaltend ein reaktionsprodukt zwischen einem cytotoxischen aldehyd und penicillamin und deren verwendung zur herstellung von arzneimitteln. - Google Patents
Antitumorzusammensetzungen enthaltend ein reaktionsprodukt zwischen einem cytotoxischen aldehyd und penicillamin und deren verwendung zur herstellung von arzneimitteln.Info
- Publication number
- ATE80801T1 ATE80801T1 AT86900504T AT86900504T ATE80801T1 AT E80801 T1 ATE80801 T1 AT E80801T1 AT 86900504 T AT86900504 T AT 86900504T AT 86900504 T AT86900504 T AT 86900504T AT E80801 T1 ATE80801 T1 AT E80801T1
- Authority
- AT
- Austria
- Prior art keywords
- reaction product
- pharmaceutically acceptable
- antitumors
- penicillamin
- pharmaceuticals
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68299184A | 1984-12-18 | 1984-12-18 | |
PCT/US1985/002480 WO1986003677A1 (en) | 1984-12-18 | 1985-12-16 | Anti-tumor compositions containing the reaction product of a cytotoxic aldehyde with penicillamine and method of use thereof |
EP86900504A EP0226591B1 (de) | 1984-12-18 | 1985-12-16 | Antitumorzusammensetzungen enthaltend ein reaktionsprodukt zwischen einem cytotoxischen aldehyd und penicillamin und deren verwendung zur herstellung von arzneimitteln |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE80801T1 true ATE80801T1 (de) | 1992-10-15 |
Family
ID=24742098
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT86900504T ATE80801T1 (de) | 1984-12-18 | 1985-12-16 | Antitumorzusammensetzungen enthaltend ein reaktionsprodukt zwischen einem cytotoxischen aldehyd und penicillamin und deren verwendung zur herstellung von arzneimitteln. |
Country Status (9)
Country | Link |
---|---|
US (1) | US5169858A (de) |
EP (1) | EP0226591B1 (de) |
JP (1) | JPS62501769A (de) |
AT (1) | ATE80801T1 (de) |
AU (1) | AU642393B2 (de) |
CA (1) | CA1303505C (de) |
DE (1) | DE3586683T2 (de) |
WO (1) | WO1986003677A1 (de) |
ZA (1) | ZA864961B (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5760008A (en) * | 1991-11-04 | 1998-06-02 | Co Enzyme Technology Ltd. | Method and compositions for treating malignant tumors and inhibiting metastases of malignant tumors |
US5476842A (en) * | 1991-11-04 | 1995-12-19 | Co Enzyme Technology Ltd. | Method and compositions for treating tumors having high tyrosinase activity |
US6083966A (en) * | 1998-08-31 | 2000-07-04 | University Of Florida | Thiazoline acid derivatives |
US6703050B1 (en) * | 1998-09-04 | 2004-03-09 | The Regents Of The University Of Michigan | Methods and compositions for the prevention or treatment of cancer |
CA2344913A1 (en) * | 1998-09-21 | 2000-03-30 | University Of Florida Research Foundation, Inc. | Antimalarial agents |
CA2490541A1 (en) * | 2002-05-24 | 2003-12-04 | The Regents Of The University Of Michigan | Copper lowering treatment of inflammatory and fibrotic diseases |
US20070248689A1 (en) * | 2002-05-24 | 2007-10-25 | Regents Of The University Of Michigan | Copper lowering treatment of inflammatory and fibrotic diseases |
MXPA05000875A (es) | 2002-07-23 | 2005-09-30 | Univ Michigan | Tetratiomolibdato de tetrapropilamonio y compuestos relacionados para terapias anti-angiogenicas. |
AU2003270473A1 (en) * | 2003-09-09 | 2005-04-27 | University Of Florida | Desferrithiocin derivatives and their use as iron chelators |
TR201910900T4 (tr) | 2005-04-04 | 2019-08-21 | Univ Florida | Desferritiyokin polieter analogları. |
CA2680592C (en) * | 2007-03-15 | 2016-07-05 | University Of Florida Research Foundation, Inc. | Desferrithiocin polyether analogues and uses thereof in treating pathological conditions |
CA2859406C (en) | 2011-12-16 | 2020-08-25 | University Of Florida Research Foundation, Inc. | Uses of 4'-desferrithiocin analogs |
US9630936B2 (en) * | 2013-03-15 | 2017-04-25 | Cancer Research Technology, Llc | Methods and compositions for gamma-glutamyl cycle modulation |
EP3288557A4 (de) | 2015-04-27 | 2018-11-07 | University of Florida Research Foundation, Inc. | Metabolisch programmierte metallchelatoren und verwendungen davon |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4384001A (en) * | 1978-12-21 | 1983-05-17 | Gosalvez Mario | Treatment of tumors with thiazolidine-4-carboxylic acid |
JPS55167220A (en) * | 1979-06-14 | 1980-12-26 | Senjiyu Seiyaku Kk | Antitumor drug |
JPS5633216A (en) * | 1979-08-29 | 1981-04-03 | Shimadzu Corp | Cutting method and cutter for dynamic balancing correction device |
JPS57128625A (en) * | 1981-01-30 | 1982-08-10 | Rikagaku Kenkyusho | Carcinostatic |
-
1985
- 1985-12-16 AT AT86900504T patent/ATE80801T1/de not_active IP Right Cessation
- 1985-12-16 JP JP86500285A patent/JPS62501769A/ja active Pending
- 1985-12-16 EP EP86900504A patent/EP0226591B1/de not_active Expired - Lifetime
- 1985-12-16 WO PCT/US1985/002480 patent/WO1986003677A1/en active IP Right Grant
- 1985-12-16 DE DE8686900504T patent/DE3586683T2/de not_active Expired - Fee Related
- 1985-12-18 CA CA000498057A patent/CA1303505C/en not_active Expired - Fee Related
-
1986
- 1986-02-26 US US06/833,801 patent/US5169858A/en not_active Expired - Fee Related
- 1986-07-03 ZA ZA864961A patent/ZA864961B/xx unknown
- 1986-07-03 AU AU59726/86A patent/AU642393B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
AU642393B2 (en) | 1993-10-21 |
CA1303505C (en) | 1992-06-16 |
AU5972686A (en) | 1988-01-07 |
EP0226591A1 (de) | 1987-07-01 |
JPS62501769A (ja) | 1987-07-16 |
ZA864961B (en) | 1987-02-25 |
DE3586683D1 (de) | 1992-10-29 |
US5169858A (en) | 1992-12-08 |
DE3586683T2 (de) | 1993-04-08 |
EP0226591B1 (de) | 1992-09-23 |
EP0226591A4 (de) | 1987-06-01 |
WO1986003677A1 (en) | 1986-07-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |