TR201903312T4 - Benralizumab kullanarak astım alevlenme oranlarini azaltma yöntemleri. - Google Patents

Benralizumab kullanarak astım alevlenme oranlarini azaltma yöntemleri. Download PDF

Info

Publication number
TR201903312T4
TR201903312T4 TR2019/03312T TR201903312T TR201903312T4 TR 201903312 T4 TR201903312 T4 TR 201903312T4 TR 2019/03312 T TR2019/03312 T TR 2019/03312T TR 201903312 T TR201903312 T TR 201903312T TR 201903312 T4 TR201903312 T4 TR 201903312T4
Authority
TR
Turkey
Prior art keywords
benralizumab
antigen
binding fragment
asthma
weeks
Prior art date
Application number
TR2019/03312T
Other languages
English (en)
Turkish (tr)
Inventor
Ward Christine
Roskos Lorin
Wang Bing
Raible Donald
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of TR201903312T4 publication Critical patent/TR201903312T4/tr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/10Expectorants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Dermatology (AREA)
  • Bathtubs, Showers, And Their Attachments (AREA)
TR2019/03312T 2013-08-12 2014-08-07 Benralizumab kullanarak astım alevlenme oranlarini azaltma yöntemleri. TR201903312T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361864944P 2013-08-12 2013-08-12

Publications (1)

Publication Number Publication Date
TR201903312T4 true TR201903312T4 (tr) 2019-04-22

Family

ID=52448837

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2019/03312T TR201903312T4 (tr) 2013-08-12 2014-08-07 Benralizumab kullanarak astım alevlenme oranlarini azaltma yöntemleri.

Country Status (26)

Country Link
US (2) US9441037B2 (enExample)
EP (1) EP3033101B1 (enExample)
JP (4) JP6746495B2 (enExample)
KR (2) KR20220057637A (enExample)
CN (2) CN111588848A (enExample)
AU (2) AU2014306956B2 (enExample)
BR (1) BR112016002401A8 (enExample)
CA (1) CA2918105C (enExample)
CY (1) CY1122132T1 (enExample)
DK (1) DK3033101T3 (enExample)
ES (1) ES2716906T3 (enExample)
HK (2) HK1221644A1 (enExample)
HR (1) HRP20190405T1 (enExample)
HU (1) HUE042607T2 (enExample)
LT (1) LT3033101T (enExample)
ME (1) ME03348B (enExample)
MX (1) MX368508B (enExample)
PL (1) PL3033101T3 (enExample)
PT (1) PT3033101T (enExample)
RS (1) RS58404B1 (enExample)
RU (1) RU2676333C2 (enExample)
SG (2) SG11201600481UA (enExample)
SI (1) SI3033101T1 (enExample)
SM (1) SMT201900163T1 (enExample)
TR (1) TR201903312T4 (enExample)
WO (1) WO2015023504A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX368474B (es) * 2013-08-12 2019-10-04 Astrazeneca Ab Uso de benralizumab para mejorar síntomas de asma.
HUE053627T2 (hu) * 2013-08-12 2021-07-28 Astrazeneca Ab Módszerek a kényszerített kilégzési térfogat növelésére asztmásoknál benralizumab használatával
EP3057609A4 (en) * 2013-10-15 2017-03-22 Medlmmune, LLC Methods for treating chronic obstructive pulmonary disease using benralizumab
HRP20211371T1 (hr) * 2013-10-24 2021-11-26 Astrazeneca Ab Stabilne, vodene formulacije protutijela
AU2015204674B2 (en) 2014-01-10 2020-09-03 Anaptysbio, Inc. Antibodies directed against interleukin-33 (IL-33)
US10699274B2 (en) 2015-08-24 2020-06-30 Samsung Electronics Co., Ltd. Apparatus and method for secure electronic payment
US10846696B2 (en) 2015-08-24 2020-11-24 Samsung Electronics Co., Ltd. Apparatus and method for trusted execution environment based secure payment transactions
CA3002761A1 (en) 2015-11-04 2017-05-11 Astrazeneca Ab Dipeptidyl peptidase-4 and periostin as predictors of clinical response to eosinophil-targeted therapeutic agents in eosinophilic diseases
US11542316B2 (en) 2017-01-04 2023-01-03 Worg Pharmaceuticals (Zhejiang) Co., Ltd. S-Arrestin peptides and therapeutic uses thereof
RU2698048C2 (ru) * 2017-10-03 2019-08-21 Закрытое Акционерное Общество "Биокад" МОНОКЛОНАЛЬНОЕ АНТИТЕЛО К IL-5Rα
TW202021983A (zh) * 2018-09-21 2020-06-16 美商安納普提斯生物公司 用於嗜伊紅性氣喘之抗il-33療法
TW202214692A (zh) * 2020-06-05 2022-04-16 瑞典商阿斯特捷利康公司 治療患有鼻瘜肉的患者的重度氣喘之方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0811691B1 (en) 1995-09-11 2004-12-01 Kyowa Hakko Kogyo Co., Ltd. Antibody againts alpha-chain of human interleukin 5 receptor
US6746839B1 (en) * 1998-01-12 2004-06-08 Interleukin Genetics, Inc. Diagnostics and therapeutics for an obstructive airway disease
ES2568899T3 (es) 1999-04-09 2016-05-05 Kyowa Hakko Kirin Co., Ltd. Procedimiento para controlar la actividad de una molécula inmunofuncional
EP1266663A4 (en) 2000-02-15 2003-07-23 Kyowa Hakko Kogyo Kk INDUCER OF EOSINOPHILIC SPECIFIC APOPTOSIS
US6946292B2 (en) 2000-10-06 2005-09-20 Kyowa Hakko Kogyo Co., Ltd. Cells producing antibody compositions with increased antibody dependent cytotoxic activity
US7662925B2 (en) 2002-03-01 2010-02-16 Xencor, Inc. Optimized Fc variants and methods for their generation
WO2005035583A1 (ja) 2003-10-08 2005-04-21 Kyowa Hakko Kogyo Co., Ltd. Il-5受容体に特異的に結合する抗体組成物
US20060014680A1 (en) 2004-07-13 2006-01-19 Caiding Xu Peptides and compounds that bind to the IL-5 receptor
DK1931709T3 (en) 2005-10-03 2017-03-13 Xencor Inc FC VARIETIES WITH OPTIMIZED FC RECEPTOR BINDING PROPERTIES
DK2068927T3 (da) 2007-05-14 2016-01-18 Medimmune Llc Fremgangsmåder til reducering af eosinofilniveauer
RU2383345C1 (ru) * 2008-08-07 2010-03-10 Государственное образовательное учреждение высшего профессионального образования "Нижегородская государственная медицинская академия Росздрава" (ГОУ ВПО "НИЖГМА РОСЗДРАВА") Способ лечения больных бронхиальной астмой
MX2012005661A (es) * 2009-11-18 2012-09-07 Medicinova Inc Tratamiento de exacerbacion aguda de asma y reduccion de probabilidad de hospitalizacion de pacientes que sufren de la misma.
RU2737245C2 (ru) * 2010-12-16 2020-11-26 Дженентек, Инк. Способы диагностики и лечения, связанные с ингибированием тн2
US8961965B2 (en) 2011-05-18 2015-02-24 Medimmune, Llc Methods of diagnosing and treating pulmonary diseases or disorders
KR20140097217A (ko) 2011-11-01 2014-08-06 메디뮨 엘엘씨 급성 천식 악화의 빈도 및 중증도를 감소시키는 방법
HUE053627T2 (hu) * 2013-08-12 2021-07-28 Astrazeneca Ab Módszerek a kényszerített kilégzési térfogat növelésére asztmásoknál benralizumab használatával
MX368474B (es) * 2013-08-12 2019-10-04 Astrazeneca Ab Uso de benralizumab para mejorar síntomas de asma.

Also Published As

Publication number Publication date
US9441037B2 (en) 2016-09-13
AU2014306956A1 (en) 2016-02-04
ES2716906T3 (es) 2019-06-17
EP3033101A4 (en) 2017-07-12
ME03348B (me) 2019-10-20
PT3033101T (pt) 2019-04-02
RU2016108723A3 (enExample) 2018-06-18
MX2016001383A (es) 2016-08-03
JP6746495B2 (ja) 2020-08-26
SMT201900163T1 (it) 2019-05-10
KR20220057637A (ko) 2022-05-09
HRP20190405T1 (hr) 2019-04-19
RU2016108723A (ru) 2017-09-19
BR112016002401A2 (pt) 2017-09-12
CY1122132T1 (el) 2020-11-25
JP2024129139A (ja) 2024-09-26
WO2015023504A8 (en) 2015-09-24
AU2020201327A1 (en) 2020-03-12
HK1225302B (en) 2017-09-08
US20150044202A1 (en) 2015-02-12
WO2015023504A1 (en) 2015-02-19
SI3033101T1 (sl) 2019-04-30
JP2016527324A (ja) 2016-09-08
CN105451760A (zh) 2016-03-30
CN111588848A (zh) 2020-08-28
RS58404B1 (sr) 2019-04-30
DK3033101T3 (en) 2019-04-08
EP3033101B1 (en) 2018-12-19
RU2676333C2 (ru) 2018-12-28
CA2918105A1 (en) 2015-02-19
SG10202005560UA (en) 2020-07-29
MX368508B (es) 2019-10-07
KR20160042121A (ko) 2016-04-18
CA2918105C (en) 2023-02-28
JP2022120009A (ja) 2022-08-17
BR112016002401A8 (pt) 2018-06-12
EP3033101A1 (en) 2016-06-22
HK1221644A1 (zh) 2017-06-09
JP2020128375A (ja) 2020-08-27
SG11201600481UA (en) 2016-02-26
AU2014306956B2 (en) 2019-11-21
US20170198049A1 (en) 2017-07-13
PL3033101T3 (pl) 2019-06-28
LT3033101T (lt) 2019-03-25
KR102390714B1 (ko) 2022-04-26
HUE042607T2 (hu) 2019-07-29

Similar Documents

Publication Publication Date Title
TR201903312T4 (tr) Benralizumab kullanarak astım alevlenme oranlarini azaltma yöntemleri.
HK1225302A1 (en) Methods for reducing exacerbation rates of asthma using benralizumab
CA2917603C (en) Methods for increasing forced expiratory volume in asthmatics using benralizumab
AU2020202564A1 (en) Methods for improving asthma symptoms using benralizumab
RU2840902C2 (ru) Способы нормализации симптомов астмы с применением бенрализумаба
HK40064505A (en) Methods for improving asthma symptoms using benralizumab
HK40013807A (en) Methods for improving asthma symptoms using benralizumab
HK40013807B (en) Methods for improving asthma symptoms using benralizumab
HK40012636A (en) Methods for increasing forced expiratory volume in asthmatics using benralizumab
HK40012636B (en) Methods for increasing forced expiratory volume in asthmatics using benralizumab
HK1225303B (en) Methods for improving asthma symptoms using benralizumab
HK1225300B (en) Methods for increasing forced expiratory volume in asthmatics using benralizumab