SG10202005560UA - Methods for reducing exacerbation rates of asthma using benralizumab - Google Patents

Methods for reducing exacerbation rates of asthma using benralizumab

Info

Publication number
SG10202005560UA
SG10202005560UA SG10202005560UA SG10202005560UA SG10202005560UA SG 10202005560U A SG10202005560U A SG 10202005560UA SG 10202005560U A SG10202005560U A SG 10202005560UA SG 10202005560U A SG10202005560U A SG 10202005560UA SG 10202005560U A SG10202005560U A SG 10202005560UA
Authority
SG
Singapore
Prior art keywords
benralizumab
asthma
methods
exacerbation rates
reducing exacerbation
Prior art date
Application number
SG10202005560UA
Inventor
Christine Ward
Lorin Roskos
Bing Wang
Donald Raible
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of SG10202005560UA publication Critical patent/SG10202005560UA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/10Expectorants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Dermatology (AREA)
SG10202005560UA 2013-08-12 2014-08-07 Methods for reducing exacerbation rates of asthma using benralizumab SG10202005560UA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361864944P 2013-08-12 2013-08-12

Publications (1)

Publication Number Publication Date
SG10202005560UA true SG10202005560UA (en) 2020-07-29

Family

ID=52448837

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201600481UA SG11201600481UA (en) 2013-08-12 2014-08-07 Methods for reducing exacerbation rates of asthma using benralizumab
SG10202005560UA SG10202005560UA (en) 2013-08-12 2014-08-07 Methods for reducing exacerbation rates of asthma using benralizumab

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11201600481UA SG11201600481UA (en) 2013-08-12 2014-08-07 Methods for reducing exacerbation rates of asthma using benralizumab

Country Status (25)

Country Link
US (2) US9441037B2 (en)
EP (1) EP3033101B1 (en)
JP (4) JP6746495B2 (en)
KR (2) KR20220057637A (en)
CN (2) CN105451760A (en)
AU (2) AU2014306956B2 (en)
BR (1) BR112016002401A8 (en)
CA (1) CA2918105C (en)
CY (1) CY1122132T1 (en)
DK (1) DK3033101T3 (en)
ES (1) ES2716906T3 (en)
HK (2) HK1221644A1 (en)
HR (1) HRP20190405T1 (en)
HU (1) HUE042607T2 (en)
LT (1) LT3033101T (en)
ME (1) ME03348B (en)
MX (1) MX368508B (en)
PL (1) PL3033101T3 (en)
PT (1) PT3033101T (en)
RS (1) RS58404B1 (en)
RU (1) RU2676333C2 (en)
SG (2) SG11201600481UA (en)
SI (1) SI3033101T1 (en)
TR (1) TR201903312T4 (en)
WO (1) WO2015023504A1 (en)

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PT3520811T (en) * 2013-08-12 2021-03-15 Astrazeneca Ab Methods for increasing forced expiratory volume in asthmatics using benralizumab
HUE057065T2 (en) * 2013-08-12 2022-04-28 Astrazeneca Ab Methods for improving asthma symptoms using benralizumab
EP3057609A4 (en) * 2013-10-15 2017-03-22 Medlmmune, LLC Methods for treating chronic obstructive pulmonary disease using benralizumab
MX2016004605A (en) * 2013-10-24 2016-11-14 Astrazeneca Ab Stable, aqueous antibody formulations.
KR102446386B1 (en) 2014-01-10 2022-09-22 아납티스바이오, 아이엔씨. Antibodies directed against interleukin-33 (il-33)
US10699274B2 (en) 2015-08-24 2020-06-30 Samsung Electronics Co., Ltd. Apparatus and method for secure electronic payment
US10846696B2 (en) 2015-08-24 2020-11-24 Samsung Electronics Co., Ltd. Apparatus and method for trusted execution environment based secure payment transactions
AU2016349113A1 (en) 2015-11-04 2018-06-07 Astrazeneca Ab Dipeptidyl peptidase-4 and periostin as predictors of clinical response to eosinophil-targeted therapeutic agents in eosinophilic diseases
ES2981555T3 (en) 2017-01-04 2024-10-09 Worg Pharmaceuticals Zhejiang Co Ltd S-arrestin peptides and their therapeutic uses
RU2698048C2 (en) * 2017-10-03 2019-08-21 Закрытое Акционерное Общество "Биокад" Monoclonal antibody to il-5rα
TW202021983A (en) * 2018-09-21 2020-06-16 美商安納普提斯生物公司 Anti-il-33 therapy for eosinophilic asthma
TW202214692A (en) * 2020-06-05 2022-04-16 瑞典商阿斯特捷利康公司 Methods for treating severe asthma in patients with nasal polyposis

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KR100259828B1 (en) 1995-09-11 2000-06-15 히라타 다다시 Antibody againsts alpha-chain of human interleukin 5 receptor
US6746839B1 (en) * 1998-01-12 2004-06-08 Interleukin Genetics, Inc. Diagnostics and therapeutics for an obstructive airway disease
ES2571230T3 (en) 1999-04-09 2016-05-24 Kyowa Hakko Kirin Co Ltd Procedure to control the activity of an immunofunctional molecule
EP1266663A4 (en) 2000-02-15 2003-07-23 Kyowa Hakko Kogyo Kk Eosinophil-specific apoptosis inducer
US6946292B2 (en) 2000-10-06 2005-09-20 Kyowa Hakko Kogyo Co., Ltd. Cells producing antibody compositions with increased antibody dependent cytotoxic activity
US8093357B2 (en) 2002-03-01 2012-01-10 Xencor, Inc. Optimized Fc variants and methods for their generation
AU2004279740A1 (en) 2003-10-08 2005-04-21 Kyowa Hakko Kirin Co., Ltd. Antibody composition specifically binding to IL-5 receptor
US20060014680A1 (en) 2004-07-13 2006-01-19 Caiding Xu Peptides and compounds that bind to the IL-5 receptor
DK1931709T3 (en) 2005-10-03 2017-03-13 Xencor Inc FC VARIETIES WITH OPTIMIZED FC RECEPTOR BINDING PROPERTIES
SI3072525T1 (en) 2007-05-14 2018-06-29 Astrazeneca Ab Methods of reducing basophil levels
RU2383345C1 (en) * 2008-08-07 2010-03-10 Государственное образовательное учреждение высшего профессионального образования "Нижегородская государственная медицинская академия Росздрава" (ГОУ ВПО "НИЖГМА РОСЗДРАВА") Method of treating patients with bronchial asthma
AU2010322066A1 (en) * 2009-11-18 2012-06-21 Medicinova, Inc. Treatment of acute exacerbation of asthma and reduction of likelihood of hospitalization of patients suffering therefrom
NZ713202A (en) * 2010-12-16 2017-12-22 Genentech Inc Diagnosis and treatments relating to th2 inhibition
WO2012158954A1 (en) * 2011-05-18 2012-11-22 Medimmune, Llc Methods of diagnosing and treating pulmonary diseases or disorders
US20140328839A1 (en) 2011-11-01 2014-11-06 Medlmmune, Llc Methods For Reducing The Frequency And Severity Of Acute Exacerbations Of Asthma
PT3520811T (en) * 2013-08-12 2021-03-15 Astrazeneca Ab Methods for increasing forced expiratory volume in asthmatics using benralizumab
HUE057065T2 (en) 2013-08-12 2022-04-28 Astrazeneca Ab Methods for improving asthma symptoms using benralizumab

Also Published As

Publication number Publication date
WO2015023504A8 (en) 2015-09-24
KR20160042121A (en) 2016-04-18
AU2014306956A1 (en) 2016-02-04
EP3033101B1 (en) 2018-12-19
EP3033101A4 (en) 2017-07-12
SG11201600481UA (en) 2016-02-26
SI3033101T1 (en) 2019-04-30
KR102390714B1 (en) 2022-04-26
ES2716906T3 (en) 2019-06-17
HUE042607T2 (en) 2019-07-29
PT3033101T (en) 2019-04-02
HK1225302B (en) 2017-09-08
CY1122132T1 (en) 2020-11-25
CA2918105A1 (en) 2015-02-19
JP2022120009A (en) 2022-08-17
RS58404B1 (en) 2019-04-30
ME03348B (en) 2019-10-20
KR20220057637A (en) 2022-05-09
AU2020201327A1 (en) 2020-03-12
MX2016001383A (en) 2016-08-03
CA2918105C (en) 2023-02-28
JP6746495B2 (en) 2020-08-26
JP2024129139A (en) 2024-09-26
JP2020128375A (en) 2020-08-27
WO2015023504A1 (en) 2015-02-19
US20170198049A1 (en) 2017-07-13
BR112016002401A2 (en) 2017-09-12
AU2014306956B2 (en) 2019-11-21
LT3033101T (en) 2019-03-25
MX368508B (en) 2019-10-07
DK3033101T3 (en) 2019-04-08
BR112016002401A8 (en) 2018-06-12
HK1221644A1 (en) 2017-06-09
US9441037B2 (en) 2016-09-13
EP3033101A1 (en) 2016-06-22
RU2676333C2 (en) 2018-12-28
JP2016527324A (en) 2016-09-08
PL3033101T3 (en) 2019-06-28
RU2016108723A3 (en) 2018-06-18
TR201903312T4 (en) 2019-04-22
CN105451760A (en) 2016-03-30
RU2016108723A (en) 2017-09-19
HRP20190405T1 (en) 2019-04-19
CN111588848A (en) 2020-08-28
US20150044202A1 (en) 2015-02-12

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