TR201818992T4 - Polimerik Finasterid Nanoparçacık, Bunu İçeren Sulu Bileşim, Alopesi Tedavisine Yönelik Bileşim, Bahsedilen Bileşimi Hazırlamaya Yönelik Metot Ve Bunların Kullanımı - Google Patents

Polimerik Finasterid Nanoparçacık, Bunu İçeren Sulu Bileşim, Alopesi Tedavisine Yönelik Bileşim, Bahsedilen Bileşimi Hazırlamaya Yönelik Metot Ve Bunların Kullanımı Download PDF

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TR201818992T4
TR201818992T4 TR2018/18992T TR201818992T TR201818992T4 TR 201818992 T4 TR201818992 T4 TR 201818992T4 TR 2018/18992 T TR2018/18992 T TR 2018/18992T TR 201818992 T TR201818992 T TR 201818992T TR 201818992 T4 TR201818992 T4 TR 201818992T4
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Turkey
Prior art keywords
composition
alopecia
treatment
finasteride
polymeric
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TR2018/18992T
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English (en)
Inventor
Raffin Pohlmann Adrian
Duarte Jornada Denise
Stanisçuaski Guterres Silva
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Biolab Sanus Farmaceutica Ltda
Univ Federal Do Rio Grande Do Sul Ufrgs
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50182295&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TR201818992(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biolab Sanus Farmaceutica Ltda, Univ Federal Do Rio Grande Do Sul Ufrgs filed Critical Biolab Sanus Farmaceutica Ltda
Publication of TR201818992T4 publication Critical patent/TR201818992T4/tr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63—Steroids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241—Containing particulates characterized by their shape and/or structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/044—Suspensions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35—Ketones, e.g. benzophenone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/85—Polyesters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/592—Mixtures of compounds complementing their respective functions
    • A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/60—Particulates further characterized by their structure or composition
    • A61K2800/65—Characterized by the composition of the particulate/core
    • A61K2800/654—The particulate/core comprising macromolecular material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Dispersion Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)

Abstract

Mevcut buluş finasterid içeren, nanokapsüller biçiminde polimerik nanoparçacıklarla ve alopesi tedavisine yönelik topikal uygulama için farmasötik bir bileşimle ilgili olup, bahsedilen bileşim bahsedilen polimerik nanoparçacıkları, finasterid, katkı maddeleri ve farmasötik olarak kabul edilebilir bir taşıyıcı içeren nanokapsüller biçiminde içerir. Mevcut buluş ayrıca alopesi tedavisi için uygun olan bir topikal uygulama bileşimine uygun bahsedilen finasterid nanokapsüllerin hazırlanışına yönelik bir proses içerir. Mevcut buluş ayrıca alopesi tedavisinde kullanılmak üzere nanokapsüller biçiminde yukarıdaki nanoparçacıklarla ilgilidir.
TR2018/18992T 2012-08-31 2013-08-30 Polimerik Finasterid Nanoparçacık, Bunu İçeren Sulu Bileşim, Alopesi Tedavisine Yönelik Bileşim, Bahsedilen Bileşimi Hazırlamaya Yönelik Metot Ve Bunların Kullanımı TR201818992T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BR102012022034-2A BR102012022034B1 (pt) 2012-08-31 2012-08-31 Nanopartícula polimérica de finasterida, suspensão aquosa contendo a mesma, composição para tratamento de alopecia, processo de preparação de dita composição, e seu uso

Publications (1)

Publication Number Publication Date
TR201818992T4 true TR201818992T4 (tr) 2019-01-21

Family

ID=50182295

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TR2018/18992T TR201818992T4 (tr) 2012-08-31 2013-08-30 Polimerik Finasterid Nanoparçacık, Bunu İçeren Sulu Bileşim, Alopesi Tedavisine Yönelik Bileşim, Bahsedilen Bileşimi Hazırlamaya Yönelik Metot Ve Bunların Kullanımı

Country Status (21)

Country Link
US (1) US9895302B2 (tr)
EP (1) EP2891487B1 (tr)
JP (1) JP6235018B2 (tr)
KR (1) KR102128478B1 (tr)
CN (1) CN104768539B (tr)
AR (1) AR092402A1 (tr)
AU (1) AU2013308355B2 (tr)
BR (1) BR102012022034B1 (tr)
CA (1) CA2883996C (tr)
CL (1) CL2015000502A1 (tr)
DK (1) DK2891487T3 (tr)
ES (1) ES2702577T3 (tr)
IN (1) IN2015DN01727A (tr)
MX (1) MX357601B (tr)
PE (2) PE20191713A1 (tr)
SA (1) SA515360083B1 (tr)
TR (1) TR201818992T4 (tr)
UA (1) UA116993C2 (tr)
UY (1) UY35003A (tr)
WO (1) WO2014032151A1 (tr)
ZA (1) ZA201501254B (tr)

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KR102429536B1 (ko) * 2015-09-30 2022-08-04 (주)아모레퍼시픽 열안정성 현탁 화장료 조성물
US11622929B2 (en) 2016-03-08 2023-04-11 Living Proof, Inc. Long lasting cosmetic compositions
JP6835867B2 (ja) 2016-03-18 2021-02-24 ケアジェン カンパニー, リミテッドCaregen Co., Ltd. フィナステリドとペプチドの結合体
JPWO2018180966A1 (ja) * 2017-03-28 2019-06-27 富士フイルム株式会社 マイクロカプセル及びその製造方法
WO2018206077A1 (en) * 2017-05-08 2018-11-15 Merz Pharma Gmbh & Co. Kgaa Emulsion comprising finasteride
WO2019055445A2 (en) 2017-09-13 2019-03-21 Living Proof, Inc. COLOR PROTECTION COMPOSITIONS
CN111133023B (zh) 2017-09-13 2022-10-18 生活实验公司 持久化妆品组合物
CN110448525A (zh) * 2018-05-08 2019-11-15 无锡派列博生物医药科技有限公司 一种预防脱发和促生发的外用非那雄胺脂质纳米制剂及其制备方法
KR102644611B1 (ko) 2018-11-29 2024-03-07 (주)아모레퍼시픽 탈모 또는 피부 염증 억제용 조성물
KR20200099901A (ko) * 2019-02-15 2020-08-25 (주)인벤티지랩 피나스테라이드를 포함하는 마이크로 입자를 함유한 피하 주사용 조성물
KR102157124B1 (ko) * 2019-12-23 2020-09-18 (주)인벤티지랩 피나스테라이드를 포함하는 서방성 주사용 조성물
US20230181464A1 (en) * 2020-05-13 2023-06-15 Follicle Pharma Ltd Compositions for delivery of bioactive agents into hair follicles
EP4216938A1 (en) * 2020-09-24 2023-08-02 Pro Transit Nanotherapy LLC Compositions and methods for the treatment of hair loss and other conditions
GB2624638A (en) * 2022-11-22 2024-05-29 Landa Labs 2012 Ltd Nano-Carriers for Drug Delivery and Methods of Preparing the Same
CN115400085A (zh) * 2022-09-02 2022-11-29 南昌大学 一种非那雄胺类脂囊泡及其制备方法和应用

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Publication number Publication date
EP2891487A1 (en) 2015-07-08
CL2015000502A1 (es) 2015-10-16
CN104768539A (zh) 2015-07-08
KR102128478B1 (ko) 2020-07-01
CN104768539B (zh) 2019-03-05
US20150238406A1 (en) 2015-08-27
UY35003A (es) 2014-03-31
UA116993C2 (uk) 2018-06-11
AR092402A1 (es) 2015-04-22
EP2891487A4 (en) 2016-04-20
BR102012022034B1 (pt) 2020-02-18
JP2015526483A (ja) 2015-09-10
CA2883996A1 (en) 2014-03-06
WO2014032151A1 (pt) 2014-03-06
PE20191713A1 (es) 2019-12-05
SA515360083B1 (ar) 2017-03-01
AU2013308355B2 (en) 2017-08-31
CA2883996C (en) 2020-10-27
MX2015002299A (es) 2016-02-10
MX357601B (es) 2018-07-16
ZA201501254B (en) 2016-05-25
JP6235018B2 (ja) 2017-11-22
US9895302B2 (en) 2018-02-20
AU2013308355A1 (en) 2015-04-16
BR102012022034A2 (pt) 2014-08-19
IN2015DN01727A (tr) 2015-05-29
EP2891487B1 (en) 2018-11-28
DK2891487T3 (en) 2019-01-14
KR20150046332A (ko) 2015-04-29
PE20150731A1 (es) 2015-05-17
ES2702577T3 (es) 2019-03-04

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