TR201818983T4 - İnflamatuvar Cilt Bozukluklarının Tedavisine Yönelik Olarak Sübstitüe Edilmiş Tetrasiklin Bileşikleri - Google Patents

İnflamatuvar Cilt Bozukluklarının Tedavisine Yönelik Olarak Sübstitüe Edilmiş Tetrasiklin Bileşikleri Download PDF

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Publication number
TR201818983T4
TR201818983T4 TR2018/18983T TR201818983T TR201818983T4 TR 201818983 T4 TR201818983 T4 TR 201818983T4 TR 2018/18983 T TR2018/18983 T TR 2018/18983T TR 201818983 T TR201818983 T TR 201818983T TR 201818983 T4 TR201818983 T4 TR 201818983T4
Authority
TR
Turkey
Prior art keywords
treatment
skin disorders
inflammatory skin
compounds substituted
tetracycline compounds
Prior art date
Application number
TR2018/18983T
Other languages
English (en)
Turkish (tr)
Inventor
Assefa Haregewein
Bhatia Beena
Draper Michael
Honeyman Laura
P Molnar Dennis
K Kim Oak
Original Assignee
Paratek Pharm Innc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Paratek Pharm Innc filed Critical Paratek Pharm Innc
Publication of TR201818983T4 publication Critical patent/TR201818983T4/tr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/48—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring being part of a condensed ring system of the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
    • C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
    • C07C2603/42—Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
    • C07C2603/44—Naphthacenes; Hydrogenated naphthacenes
    • C07C2603/46—1,4,4a,5,5a,6,11,12a- Octahydronaphthacenes, e.g. tetracyclines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TR2018/18983T 2006-12-21 2007-12-21 İnflamatuvar Cilt Bozukluklarının Tedavisine Yönelik Olarak Sübstitüe Edilmiş Tetrasiklin Bileşikleri TR201818983T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87643406P 2006-12-21 2006-12-21

Publications (1)

Publication Number Publication Date
TR201818983T4 true TR201818983T4 (tr) 2019-01-21

Family

ID=39432968

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2018/18983T TR201818983T4 (tr) 2006-12-21 2007-12-21 İnflamatuvar Cilt Bozukluklarının Tedavisine Yönelik Olarak Sübstitüe Edilmiş Tetrasiklin Bileşikleri

Country Status (13)

Country Link
US (2) US8513223B2 (es)
EP (2) EP2120963B1 (es)
AU (1) AU2007338681B2 (es)
CA (2) CA2892739A1 (es)
CY (1) CY1121135T1 (es)
DK (1) DK2120963T3 (es)
ES (1) ES2701725T3 (es)
LT (1) LT2120963T (es)
PL (1) PL2120963T3 (es)
PT (1) PT2120963T (es)
SI (1) SI2120963T1 (es)
TR (1) TR201818983T4 (es)
WO (1) WO2008079363A2 (es)

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US20020123637A1 (en) * 1998-01-23 2002-09-05 Stuart B. Levy Pharmaceutically active compounds and methods of use thereof
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US20020132798A1 (en) 2000-06-16 2002-09-19 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
US7094806B2 (en) 2000-07-07 2006-08-22 Trustees Of Tufts College 7, 8 and 9-substituted tetracycline compounds
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WO2005009943A2 (en) 2003-07-09 2005-02-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
EP2949644A3 (en) * 2004-10-25 2016-04-20 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
JP2010523684A (ja) 2007-04-12 2010-07-15 パラテック ファーマシューティカルズ インコーポレイテッド テトラサイクリン化合物を用いる、脊髄筋委縮症を治療するための方法
CN102015602A (zh) 2008-03-05 2011-04-13 帕拉特克药品公司 米诺环素化合物及其使用方法
AU2009236631A1 (en) * 2008-04-14 2009-10-22 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
EP3574908A1 (en) * 2011-05-12 2019-12-04 Paratek Pharmaceuticals, Inc. Crystalline salts of (4s, 4as, 5ar, 12as)-4-dimethylamino-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2carboxylic acid amide and methods of using the same
US9119793B1 (en) 2011-06-28 2015-09-01 Medicis Pharmaceutical Corporation Gastroretentive dosage forms for doxycycline
CA2873412A1 (en) * 2012-05-14 2013-11-21 Paratek Pharmaceuticals, Inc. Methods of using (4s,4as,5ar,12as)-4-dimethylamino-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide
US10842802B2 (en) 2013-03-15 2020-11-24 Medicis Pharmaceutical Corporation Controlled release pharmaceutical dosage forms
BR112017020358A2 (pt) 2015-03-23 2018-07-17 Biopharmx Inc composição farmacêutica de tetraciclina para uso dermatológico
SG11201903846TA (en) 2016-11-01 2019-05-30 Paratek Pharm Innc 9-aminomethyl minocycline compounds and use thereof in treating community-acquired bacterial pneumonia (cabp)
CA3070663A1 (en) * 2017-07-21 2019-01-24 Almirall, Llc Treatment of non-inflammatory lesions
CN110156624B (zh) * 2019-05-29 2022-03-08 河北冀衡药业股份有限公司 一种米诺环素及其衍生物的合成方法

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Also Published As

Publication number Publication date
AU2007338681B2 (en) 2013-09-26
US20130345179A1 (en) 2013-12-26
CA2673486A1 (en) 2008-07-03
LT2120963T (lt) 2019-01-10
US20080312193A1 (en) 2008-12-18
EP2120963B1 (en) 2018-09-12
PT2120963T (pt) 2018-12-17
SI2120963T1 (sl) 2019-02-28
DK2120963T3 (en) 2019-01-14
CA2892739A1 (en) 2008-07-03
CA2673486C (en) 2015-09-08
CY1121135T1 (el) 2019-12-11
WO2008079363A2 (en) 2008-07-03
ES2701725T3 (es) 2019-02-25
AU2007338681A1 (en) 2008-07-03
US8513223B2 (en) 2013-08-20
US9481639B2 (en) 2016-11-01
WO2008079363A3 (en) 2008-10-02
EP2120963A2 (en) 2009-11-25
PL2120963T3 (pl) 2019-05-31
EP3488853A1 (en) 2019-05-29

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