TR201809040T4 - Solid tümörlerin tedavisi. - Google Patents
Solid tümörlerin tedavisi. Download PDFInfo
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- TR201809040T4 TR201809040T4 TR2018/09040T TR201809040T TR201809040T4 TR 201809040 T4 TR201809040 T4 TR 201809040T4 TR 2018/09040 T TR2018/09040 T TR 2018/09040T TR 201809040 T TR201809040 T TR 201809040T TR 201809040 T4 TR201809040 T4 TR 201809040T4
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1100201 | 2011-03-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR201809040T4 true TR201809040T4 (tr) | 2018-07-23 |
Family
ID=46879602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2018/09040T TR201809040T4 (tr) | 2011-03-21 | 2012-03-14 | Solid tümörlerin tedavisi. |
Country Status (20)
| Country | Link |
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| WO (1) | WO2012128689A1 (OSRAM) |
| ZA (1) | ZA201307036B (OSRAM) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112015006370B1 (pt) * | 2012-09-21 | 2022-04-12 | Vivolux Ab | Composto citotóxico, sal farmaceuticamente aceitável do mesmo, mistura, composição farmacêutica e uso do referido composto |
| US12383518B2 (en) | 2013-11-03 | 2025-08-12 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Disulfide-masked pro-chelator compositions and methods of use |
| US11504346B2 (en) | 2013-11-03 | 2022-11-22 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Redox-activated pro-chelators |
| CN105807976B (zh) | 2014-12-31 | 2019-02-12 | 清华大学 | 静电传感器 |
| US10548930B2 (en) * | 2015-04-17 | 2020-02-04 | Memorial Sloan Kettering Cancer Center | Use of MVA or MVAΔE3L as immunotherapeutic agents against solid tumors |
| CN104997777A (zh) * | 2015-07-24 | 2015-10-28 | 孔小乐 | 去铁酮的2比1锌络合物作为制备抗癌药物的应用 |
| JP7103745B2 (ja) * | 2015-10-05 | 2022-07-20 | 国立大学法人 岡山大学 | 癌幹細胞抑制剤、癌の転移又は再発の抑制剤並びに癌細胞の未分化マーカー発現抑制剤 |
| HUE059610T2 (hu) * | 2015-12-18 | 2022-12-28 | Vivolux Ab | Gyógyszerészeti készítmény, amely indolszármazékokat tartalmaz, valamint eljárás annak elõállítására és felhasználására |
| US20190358247A1 (en) * | 2016-12-21 | 2019-11-28 | The Medical College Of Wisconsin, Inc. | Synergistic inihibition of tumor cell proliferation induced by combined treatment of metformin or metformin analogs and iron chelators |
| KR101859922B1 (ko) * | 2017-02-07 | 2018-05-21 | 주식회사 온코크로스 | 클로페네신을 포함하는 대장암 증식 및 전이 억제용 조성물 |
| JP6900067B2 (ja) * | 2017-02-07 | 2021-07-07 | オンコクロス カンパニー，リミテッド | 癌の転移抑制および治療用組成物 |
| CN106831776B (zh) * | 2017-03-16 | 2018-12-07 | 河北科技大学 | 5,10-二氢吡啶并吡嗪并三嗪类化合物及其应用 |
| US11931349B2 (en) * | 2017-11-23 | 2024-03-19 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Iron chelators in tumor therapy |
| CN109646679A (zh) * | 2019-01-28 | 2019-04-19 | 中国科学院长春应用化学研究所 | 铁离子螯合剂及其可药用盐的用途 |
| CN110585194A (zh) * | 2019-10-12 | 2019-12-20 | 广州医科大学附属第五医院 | 倍半萜内酯类化合物在制备溶酶体自噬抑制剂以及抗癌药物中的应用 |
| WO2021231798A1 (en) | 2020-05-13 | 2021-11-18 | Disc Medicine, Inc. | Anti-hemojuvelin (hjv) antibodies for treating myelofibrosis |
| CN111849873A (zh) * | 2020-07-30 | 2020-10-30 | 扬州大学 | 一种诱导鸡的胚胎干细胞自噬的方法 |
| WO2025263876A1 (ko) | 2024-06-17 | 2025-12-26 | 서울대학교산학협력단 | Vlx600을 포함하는 항균 또는 항진균용 조성물 및 세균 또는 진균 감염증의 예방 또는 치료용 약학적 조성물 |
Family Cites Families (11)
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| JPH075608B2 (ja) * | 1986-01-13 | 1995-01-25 | イ−ル−セルタ−ク ソシエテ アノニム | ビンブラスチン誘導体 |
| US5480906A (en) * | 1994-07-01 | 1996-01-02 | Eli Lilly And Company | Stereochemical Wortmannin derivatives |
| IL121272A (en) * | 1997-07-10 | 2000-06-01 | Can Fite Technologies Ltd | Pharmaceutical compositions comprising adenosine and their use for treating or preventing leukopenia |
| US6660737B2 (en) * | 2001-05-04 | 2003-12-09 | The Procter & Gamble Company | Medicinal uses of hydrazones |
| CA2515027A1 (en) * | 2003-02-05 | 2004-08-19 | Unisearch Limited | Metal ion chelators and therapeutic use thereof |
| US7767689B2 (en) | 2004-03-15 | 2010-08-03 | Ptc Therapeutics, Inc. | Carboline derivatives useful in the treatment of cancer |
| US20060128805A1 (en) | 2004-11-19 | 2006-06-15 | Shah Sudhir V | Methods of treating erythropoietin-resistance |
| EP2026800A1 (en) * | 2006-05-09 | 2009-02-25 | Novartis AG | Combination comprising an iron chelator and an anti-neoplastic agent and use thereof |
| WO2009035534A2 (en) * | 2007-09-07 | 2009-03-19 | The Cleveland Clinic Foundation | Treatment of ischemic eye disease by the systematic pharmaceutical activation of hypoxia inducible factor (hif) |
| KR101208587B1 (ko) | 2009-06-24 | 2012-12-06 | 여오영 | 하이드록시클로로퀸을 포함하는 항암 치료를 위한 국소 투여용 주사제 조성물 |
| BR112015006370B1 (pt) | 2012-09-21 | 2022-04-12 | Vivolux Ab | Composto citotóxico, sal farmaceuticamente aceitável do mesmo, mistura, composição farmacêutica e uso do referido composto |
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2012
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- 2012-03-14 PT PT127602605T patent/PT2688569T/pt unknown
- 2012-03-14 HU HUE12760260A patent/HUE039021T2/hu unknown
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- 2012-03-14 EA EA201391286A patent/EA025180B1/ru not_active IP Right Cessation
- 2012-03-14 ES ES12760260.5T patent/ES2681703T3/es active Active
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- 2012-03-14 DK DK12760260.5T patent/DK2688569T3/en active
- 2012-03-14 WO PCT/SE2012/000034 patent/WO2012128689A1/en not_active Ceased
- 2012-03-14 AU AU2012231814A patent/AU2012231814B2/en active Active
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- 2012-03-14 KR KR1020137027532A patent/KR101937279B1/ko active Active
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Also Published As
| Publication number | Publication date |
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| AU2012231814B2 (en) | 2016-06-09 |
| KR101937279B1 (ko) | 2019-01-10 |
| IL228411A0 (en) | 2013-12-31 |
| ZA201307036B (en) | 2014-05-28 |
| PL2688569T3 (pl) | 2018-09-28 |
| BR112013024211B1 (pt) | 2020-12-15 |
| EP2688569A4 (en) | 2014-09-10 |
| EP2688569B1 (en) | 2018-05-30 |
| ES2681703T3 (es) | 2018-09-14 |
| CN103547268A (zh) | 2014-01-29 |
| DK2688569T3 (en) | 2018-08-06 |
| PT2688569T (pt) | 2018-08-06 |
| SG10201605083SA (en) | 2016-08-30 |
| JP6064215B2 (ja) | 2017-02-01 |
| US20170348317A1 (en) | 2017-12-07 |
| HUE039021T2 (hu) | 2018-12-28 |
| US20140073645A1 (en) | 2014-03-13 |
| EA025180B1 (ru) | 2016-11-30 |
| SG193494A1 (en) | 2013-10-30 |
| CA2830081A1 (en) | 2012-09-27 |
| KR20140017619A (ko) | 2014-02-11 |
| JP2014508804A (ja) | 2014-04-10 |
| WO2012128689A1 (en) | 2012-09-27 |
| CA2830081C (en) | 2020-09-22 |
| EP2688569A1 (en) | 2014-01-29 |
| CN103547268B (zh) | 2017-02-22 |
| EA201391286A1 (ru) | 2014-03-31 |
| US10022380B2 (en) | 2018-07-17 |
| AU2012231814A1 (en) | 2013-09-26 |
| IL228411A (en) | 2016-12-29 |
| MX2013010770A (es) | 2014-03-27 |
| BR112013024211A2 (pt) | 2016-12-20 |
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