TR200202308T2 - Prostaglandin E1 içeren tropikal bileşimler - Google Patents
Prostaglandin E1 içeren tropikal bileşimlerInfo
- Publication number
- TR200202308T2 TR200202308T2 TR2002/02308T TR200202308T TR200202308T2 TR 200202308 T2 TR200202308 T2 TR 200202308T2 TR 2002/02308 T TR2002/02308 T TR 2002/02308T TR 200202308 T TR200202308 T TR 200202308T TR 200202308 T2 TR200202308 T2 TR 200202308T2
- Authority
- TR
- Turkey
- Prior art keywords
- tropical
- prostaglandin
- compounds containing
- aliphatic
- mixture
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Transdermal prostaglandin E1 uygulanmasi için yari kati topik bir bilesim verilmektedir. Bilesimde prostaglandin E1, penetrasyon kolaylastirici, polisakkarit reçine, lipofilik bir bilesik ve asidik tampon sistemi bulunmaktadir. Penetrasyon kolaylastirici alkil-2-(sübstitüe amino)-alkanoat esterinin, (substitüe amino)-alkanol alkanoatin veya bunlarin karisiminin asit adisyon tuzudur. Lipofilik bilesik alifatik C1 ila C8 alkol, alifatik C8 veya C30 ester veya bunlarin karisimi olabilir. Bilesimde adi geçen bilesim tamponlanmis pH degerinin 3 ile 7.4 arasinda kalmasini saglayacak bir tampon sistemi bulunmaktadir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/542,668 US6414028B1 (en) | 1997-11-05 | 2000-04-04 | Topical compositions containing prostaglandin E1 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200202308T2 true TR200202308T2 (tr) | 2005-07-21 |
Family
ID=24164793
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2002/02308T TR200202308T2 (tr) | 2000-04-04 | 2001-04-04 | Prostaglandin E1 içeren tropikal bileşimler |
Country Status (16)
Country | Link |
---|---|
US (1) | US6414028B1 (tr) |
EP (1) | EP1278495A4 (tr) |
JP (1) | JP2004514646A (tr) |
KR (1) | KR20030060769A (tr) |
CN (1) | CN1203895C (tr) |
AU (1) | AU2001249792A1 (tr) |
BR (1) | BR0109863A (tr) |
CA (1) | CA2405293A1 (tr) |
HK (1) | HK1059558A1 (tr) |
HU (1) | HUP0302452A2 (tr) |
IL (1) | IL152084A0 (tr) |
MX (1) | MXPA02009798A (tr) |
NZ (1) | NZ522363A (tr) |
TR (1) | TR200202308T2 (tr) |
WO (1) | WO2001074279A1 (tr) |
ZA (1) | ZA200208803B (tr) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050004226A1 (en) * | 1998-12-10 | 2005-01-06 | Nexmed (Holdings), Inc. | Compositions and methods for amelioration of human female sexual dysfunction |
EA008720B1 (ru) * | 1998-12-10 | 2007-06-29 | Нексмед (Холдингс), Инк. | Применение композиции на основе простагландина для лечения расстройства сексуального возбуждения у женщин |
US6825234B2 (en) * | 1998-12-10 | 2004-11-30 | Nexmed (Holdings) , Inc. | Compositions and methods for amelioration of human female sexual dysfunction |
US7105571B2 (en) * | 2000-01-10 | 2006-09-12 | Nexmed Holdings, Inc. | Prostaglandin compositions and methods of treatment for male erectile dysfunction |
US6693135B2 (en) * | 2000-01-10 | 2004-02-17 | Nexmed (Holdings) Incorporated | Prostaglandin compositions and methods of treatment for male erectile dysfunction |
US6673841B2 (en) * | 2001-12-20 | 2004-01-06 | Whan In Pharm. Co., Ltd. | Alprostadil alkyl ester-containing composition for external application |
BR0307345A (pt) * | 2002-02-15 | 2004-12-14 | Nexmed Holdings Inc | Métodos para tratar disfunção erétil, para melhorar a microcirculação da glans penis e para produzir intumescência da glans penis em um paciente necessitando de tais tratamentos, artigo de manufatura, e, composição |
GB0222522D0 (en) | 2002-09-27 | 2002-11-06 | Controlled Therapeutics Sct | Water-swellable polymers |
US20050181030A1 (en) * | 2003-01-03 | 2005-08-18 | Mo Y. J. | Topical stabilized prostaglandin E compound dosage forms |
US6841574B2 (en) * | 2003-01-03 | 2005-01-11 | Nexmed Holdings, Inc. | Topical stabilized prostaglandin E compound dosage forms |
MXPA05010069A (es) * | 2003-03-21 | 2005-11-23 | Nexmed Holdings Inc | Composiciones de prostaglandina para el tratamiento de la disfuncion erectil. |
US20040241243A1 (en) * | 2003-03-21 | 2004-12-02 | Nexmed (Holdings) Inc. | Angiogenesis promotion by prostaglandin compositions and methods |
KR20050119187A (ko) * | 2003-04-02 | 2005-12-20 | 넥스메드 홀딩스 인코포레이티드 | 프로스타글란딘 조성물 및 이의 혈관연축 치료용 용도 |
GB0315671D0 (en) * | 2003-07-04 | 2003-08-13 | Chelsea And Westminster Nhs Tr | Improvements in or relating to organic compounds |
US20060204526A1 (en) * | 2003-08-13 | 2006-09-14 | Lathrop Robert W | Emulsive composition containing Dapsone |
WO2005051960A2 (en) * | 2003-11-22 | 2005-06-09 | Midwest Research Laboratories, Llc | Hydrocarbyl aminohydrocarbonoates and aminohydrocarbonol hydrocarbonoates as antimicrobial and antiviral agents |
GB0417401D0 (en) | 2004-08-05 | 2004-09-08 | Controlled Therapeutics Sct | Stabilised prostaglandin composition |
US20090053290A1 (en) * | 2006-03-08 | 2009-02-26 | Sand Bruce J | Transdermal drug delivery compositions and topical compositions for application on the skin |
GB0613333D0 (en) | 2006-07-05 | 2006-08-16 | Controlled Therapeutics Sct | Hydrophilic polyurethane compositions |
GB0613638D0 (en) | 2006-07-08 | 2006-08-16 | Controlled Therapeutics Sct | Polyurethane elastomers |
US7560489B2 (en) * | 2006-10-11 | 2009-07-14 | Nexmed Holdings, Inc. | Stabilized prostaglandin E composition |
GB0620685D0 (en) | 2006-10-18 | 2006-11-29 | Controlled Therapeutics Sct | Bioresorbable polymers |
JP5297631B2 (ja) * | 2007-11-13 | 2013-09-25 | 花王株式会社 | 皮膚外用組成物 |
CN102202509A (zh) | 2008-10-03 | 2011-09-28 | 尼克斯梅德控股公司 | 用于治疗牛皮癣的稳定化组合物 |
RU2012153177A (ru) * | 2010-05-04 | 2014-06-20 | Нексмед Холдингс, Инк. | Композиции низкомолекулярных терапевтических средств |
CA2838109C (en) | 2011-04-07 | 2020-06-09 | Nexmed Holdings, Inc. | Topical semisolid prostaglandin e1 composition for treating raynaud's disease |
ITRM20120036A1 (it) | 2012-02-02 | 2013-08-03 | Robert Davis Steigerwalt Jr | Applicazione transdermica di prostaglandina e1 per il trattamento dell¿ischemia oculare. |
KR20220164506A (ko) * | 2020-03-11 | 2022-12-13 | 어드밴식스 레진즈 앤드 케미컬즈 엘엘씨 | 건강관리 제품을 위한 계면활성제 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK243084A (da) | 1983-05-26 | 1984-11-27 | Takeda Chemical Industries Ltd | Perkutane farmaceutiske praeparater til udvortes brug |
GB8416638D0 (en) | 1984-06-29 | 1984-08-01 | Beecham Group Plc | Topical treatment and composition |
US4732892A (en) | 1985-07-12 | 1988-03-22 | American Home Products Corporation | L-α-amino acids as transdermal penetration enhancers |
US4771004A (en) | 1986-08-29 | 1988-09-13 | Iprx, Inc. | Method for in vitro determination of transdermal absorption |
US4808414A (en) | 1986-09-29 | 1989-02-28 | Nelson Research & Development Co. | Amide penetration enhancers for transdermal delivery of systemic agents |
US4865848A (en) | 1987-02-26 | 1989-09-12 | Alza Corporation | Skin permeation enhancer compositions using sucrose esters |
US4980378A (en) | 1988-06-01 | 1990-12-25 | Odontex, Inc. | Biodegradable absorption enhancers |
US5082866A (en) | 1988-06-01 | 1992-01-21 | Odontex, Inc. | Biodegradable absorption enhancers |
US5534260A (en) | 1989-02-23 | 1996-07-09 | University Of Utah | Percutaneous drug delivery system |
US4973468A (en) | 1989-03-22 | 1990-11-27 | Cygnus Research Corporation | Skin permeation enhancer compositions |
JP3202777B2 (ja) | 1992-01-24 | 2001-08-27 | リンテック株式会社 | 経皮吸収促進剤及びテープ製剤 |
DK0738141T3 (da) | 1993-12-13 | 2008-05-19 | Avanir Pharmaceuticals | Sucroseester- og n-docosanolformuleringer |
US6083996A (en) * | 1997-11-05 | 2000-07-04 | Nexmed Holdings, Inc. | Topical compositions for NSAI drug delivery |
US6046244A (en) * | 1997-11-05 | 2000-04-04 | Nexmed Holdings, Inc. | Topical compositions for prostaglandin E1 delivery |
US5942545A (en) * | 1998-06-15 | 1999-08-24 | Macrochem Corporation | Composition and method for treating penile erectile dysfunction |
CA2341220A1 (en) * | 1998-08-20 | 2000-03-02 | 3M Innovative Properties Company | Spray on bandage and drug delivery system |
US6118020A (en) * | 1999-05-19 | 2000-09-12 | Nexmed Holdings, Inc. | Crystalline salts of dodecyl 2-(N,N-dimethylamino)-propionate |
US6323241B1 (en) * | 2000-01-10 | 2001-11-27 | Nexmed (Holdings) Inc. | Prostaglandin compositions and methods of treatment for male erectile dysfunction |
-
2000
- 2000-04-04 US US09/542,668 patent/US6414028B1/en not_active Expired - Lifetime
-
2001
- 2001-04-04 JP JP2001572026A patent/JP2004514646A/ja not_active Withdrawn
- 2001-04-04 CA CA002405293A patent/CA2405293A1/en not_active Abandoned
- 2001-04-04 AU AU2001249792A patent/AU2001249792A1/en not_active Abandoned
- 2001-04-04 BR BR0109863-2A patent/BR0109863A/pt not_active IP Right Cessation
- 2001-04-04 NZ NZ52236301A patent/NZ522363A/xx unknown
- 2001-04-04 CN CNB018103162A patent/CN1203895C/zh not_active Expired - Fee Related
- 2001-04-04 IL IL15208401A patent/IL152084A0/xx unknown
- 2001-04-04 TR TR2002/02308T patent/TR200202308T2/tr unknown
- 2001-04-04 EP EP01923062A patent/EP1278495A4/en not_active Withdrawn
- 2001-04-04 HU HU0302452A patent/HUP0302452A2/hu unknown
- 2001-04-04 WO PCT/US2001/010699 patent/WO2001074279A1/en not_active Application Discontinuation
- 2001-04-04 KR KR1020027013295A patent/KR20030060769A/ko not_active Application Discontinuation
-
2002
- 2002-10-04 MX MXPA02009798A patent/MXPA02009798A/es unknown
- 2002-10-30 ZA ZA200208803A patent/ZA200208803B/en unknown
-
2004
- 2004-04-06 HK HK04102458A patent/HK1059558A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CN1449270A (zh) | 2003-10-15 |
US6414028B1 (en) | 2002-07-02 |
CA2405293A1 (en) | 2001-10-11 |
MXPA02009798A (es) | 2003-05-27 |
HUP0302452A2 (hu) | 2003-11-28 |
IL152084A0 (en) | 2003-05-29 |
KR20030060769A (ko) | 2003-07-16 |
NZ522363A (en) | 2004-12-24 |
WO2001074279A1 (en) | 2001-10-11 |
JP2004514646A (ja) | 2004-05-20 |
HK1059558A1 (en) | 2004-07-09 |
EP1278495A1 (en) | 2003-01-29 |
EP1278495A4 (en) | 2006-03-22 |
BR0109863A (pt) | 2004-09-28 |
ZA200208803B (en) | 2003-12-19 |
CN1203895C (zh) | 2005-06-01 |
AU2001249792A1 (en) | 2001-10-15 |
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