BR0307345A - Métodos para tratar disfunção erétil, para melhorar a microcirculação da glans penis e para produzir intumescência da glans penis em um paciente necessitando de tais tratamentos, artigo de manufatura, e, composição - Google Patents

Métodos para tratar disfunção erétil, para melhorar a microcirculação da glans penis e para produzir intumescência da glans penis em um paciente necessitando de tais tratamentos, artigo de manufatura, e, composição

Info

Publication number
BR0307345A
BR0307345A BR0307345-9A BR0307345A BR0307345A BR 0307345 A BR0307345 A BR 0307345A BR 0307345 A BR0307345 A BR 0307345A BR 0307345 A BR0307345 A BR 0307345A
Authority
BR
Brazil
Prior art keywords
methods
glans penis
penis
composition
swelling
Prior art date
Application number
BR0307345-9A
Other languages
English (en)
Inventor
Koichi Okada
James L Yeager
Uyuktimkin Nadir B
Yktimkin Servet B
Original Assignee
Nexmed Holdings Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nexmed Holdings Inc filed Critical Nexmed Holdings Inc
Publication of BR0307345A publication Critical patent/BR0307345A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"MéTODOS PARA TRATAR DISFUNçãO ERéTIL, PARA MELHORAR A MICROCIRCULAçãO DA GLANS PENIS E PARA PRODUZIR INTUMESCêNCIA DA GLANS PENIS EM UM PACIENTE NECESSITANDO DE TAIS TRATAMENTOS, ARTIGO DE MANUFATURA, E, COMPOSIçãO". São fornecidos métodos para o tratamento da disfunção erétil, compreendendo colocar dentro da fossa navicularis uma quantidade de uma composição de prostaglandina semi-sólida vasoativa, suficiente para aumentar o fluxo sang³ineo na glans penis e resultando em intumescência aumentada do pênis. Em versões preferidas, o método compreende ainda prover estímulos eróticos. Em outra versão, a invenção provê um método para aumentar a intumescência da glans penis. Em outro aspecto, a invenção provê composições e artigos de manufatura para a prática dos métodos da invenção.
BR0307345-9A 2002-02-15 2003-02-14 Métodos para tratar disfunção erétil, para melhorar a microcirculação da glans penis e para produzir intumescência da glans penis em um paciente necessitando de tais tratamentos, artigo de manufatura, e, composição BR0307345A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35728202P 2002-02-15 2002-02-15
PCT/US2003/004560 WO2003070281A1 (en) 2002-02-15 2003-02-14 Prostaglandin composition for the treatment of erectile dysfunction

Publications (1)

Publication Number Publication Date
BR0307345A true BR0307345A (pt) 2004-12-14

Family

ID=27757591

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0307345-9A BR0307345A (pt) 2002-02-15 2003-02-14 Métodos para tratar disfunção erétil, para melhorar a microcirculação da glans penis e para produzir intumescência da glans penis em um paciente necessitando de tais tratamentos, artigo de manufatura, e, composição

Country Status (13)

Country Link
US (1) US20030220292A1 (pt)
EP (1) EP1482980A1 (pt)
JP (1) JP2005517725A (pt)
KR (1) KR20040082431A (pt)
CN (1) CN1610559A (pt)
AU (1) AU2003211077A1 (pt)
BR (1) BR0307345A (pt)
CA (1) CA2468631A1 (pt)
HU (1) HUP0402673A2 (pt)
IL (1) IL162154A0 (pt)
MX (1) MXPA04007828A (pt)
WO (1) WO2003070281A1 (pt)
ZA (1) ZA200404105B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7105571B2 (en) 2000-01-10 2006-09-12 Nexmed Holdings, Inc. Prostaglandin compositions and methods of treatment for male erectile dysfunction
WO2004022064A1 (en) * 2002-09-06 2004-03-18 Nexmed (Holdings), Inc. Methods of treatment of male erectile dysfunction
JP4667369B2 (ja) 2003-03-21 2011-04-13 ネックスメド ホールディングス インコーポレイテッド 早漏を治療するための組成物および方法
MXPA05010068A (es) * 2003-03-21 2005-11-23 Nexmed Holdings Inc Promocion de la angiogenesis por composiciones de prostaglandina y metodos.
US7328070B2 (en) 2005-04-28 2008-02-05 Medtronic, Inc. Multi-tube sensor for sensing urinary sphincter and urethral pressure
US8068910B2 (en) * 2005-04-28 2011-11-29 Medtronic, Inc. Flexible tube sensor for sensing urinary sphincter pressure
US7610093B2 (en) * 2005-04-28 2009-10-27 Medtronic, Inc. Implantable optical pressure sensor for sensing urinary sphincter pressure
US7623923B2 (en) * 2005-04-28 2009-11-24 Medtronic, Inc. Tube sensor for penile tumescence
US9005183B2 (en) * 2007-05-16 2015-04-14 Health Knight, Llc System and method for treating erectile dysfunction
US20100184722A1 (en) * 2008-12-19 2010-07-22 Shimoda Biotech (Pty) Ltd Inclusion complexes of alpha-cyclodextrin and sildenafil salt
CN109999359B (zh) * 2019-01-24 2021-08-13 西安蓝极医疗电子科技有限公司 基于多波长激光治疗男性勃起功能障碍的装置
CN114324674A (zh) * 2022-01-21 2022-04-12 苏州南医大创新中心 一种精液中与无精子症有关的分子标志物及其检测方法和应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3595975A (en) * 1969-07-29 1971-07-27 Holliston Lab Inc Disinfecting compositions
US5698589A (en) * 1993-06-01 1997-12-16 International Medical Innovations, Inc. Water-based topical cream containing nitroglycerin and method of preparation and use thereof
US6121276A (en) * 1994-04-22 2000-09-19 Pentech Pharmaceuticals, Inc. Apomorphine-containing dosage forms for ameliorating male erectile dysfunction
AU709113B2 (en) * 1996-01-29 1999-08-19 Regents Of The University Of California, The Method for treating sexual dysfunctions
US6037346A (en) * 1997-10-28 2000-03-14 Vivus, Inc. Local administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction
US5919474A (en) * 1997-10-28 1999-07-06 Vivus, Inc. Transurethral administration of vasoactive agents to treat peripheral vascular disease, related vascular diseases, and vascular impotence associated therewith
US6414028B1 (en) * 1997-11-05 2002-07-02 Nexmed Holdings, Inc. Topical compositions containing prostaglandin E1
US6046244A (en) * 1997-11-05 2000-04-04 Nexmed Holdings, Inc. Topical compositions for prostaglandin E1 delivery
US5942545A (en) * 1998-06-15 1999-08-24 Macrochem Corporation Composition and method for treating penile erectile dysfunction
US6486207B2 (en) * 1998-12-10 2002-11-26 Nexmed (Holdings), Inc. Compositions and methods for amelioration of human female sexual dysfunction
US6294192B1 (en) * 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
US6323241B1 (en) * 2000-01-10 2001-11-27 Nexmed (Holdings) Inc. Prostaglandin compositions and methods of treatment for male erectile dysfunction

Also Published As

Publication number Publication date
EP1482980A1 (en) 2004-12-08
MXPA04007828A (es) 2004-10-15
HUP0402673A2 (hu) 2005-04-28
ZA200404105B (en) 2005-08-26
CN1610559A (zh) 2005-04-27
IL162154A0 (en) 2005-11-20
CA2468631A1 (en) 2003-08-28
WO2003070281A1 (en) 2003-08-28
US20030220292A1 (en) 2003-11-27
AU2003211077A1 (en) 2003-09-09
KR20040082431A (ko) 2004-09-24
JP2005517725A (ja) 2005-06-16

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