TR200200599T2 - İnsan insülini monomerik analogları. - Google Patents

İnsan insülini monomerik analogları.

Info

Publication number
TR200200599T2
TR200200599T2 TR2002/00599T TR200200599T TR200200599T2 TR 200200599 T2 TR200200599 T2 TR 200200599T2 TR 2002/00599 T TR2002/00599 T TR 2002/00599T TR 200200599 T TR200200599 T TR 200200599T TR 200200599 T2 TR200200599 T2 TR 200200599T2
Authority
TR
Turkey
Prior art keywords
human insulin
monomeric analogues
analogues
insulin monomeric
chain
Prior art date
Application number
TR2002/00599T
Other languages
English (en)
Inventor
Feng You-Min
Zhang You-Shang
Original Assignee
Shanghai Institute Of Biochemistry
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Institute Of Biochemistry filed Critical Shanghai Institute Of Biochemistry
Publication of TR200200599T2 publication Critical patent/TR200200599T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

Insan insülininin monomerik analoglari, insan insülininin B zincirinin 12., 16. ya da 26. konumundaki amino asitin bir tek ikamesine sahiptir ve ayni zamanda B zincirinde bir terminal silintisine de sahip olabilecektir.
TR2002/00599T 1999-09-08 2000-09-08 İnsan insülini monomerik analogları. TR200200599T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN99116851A CN1125081C (zh) 1999-09-08 1999-09-08 重组天然和新型人胰岛素及其制备方法

Publications (1)

Publication Number Publication Date
TR200200599T2 true TR200200599T2 (tr) 2002-05-21

Family

ID=5279521

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2002/00599T TR200200599T2 (tr) 1999-09-08 2000-09-08 İnsan insülini monomerik analogları.

Country Status (15)

Country Link
US (1) US6800606B1 (tr)
EP (1) EP1210369A1 (tr)
JP (1) JP2003525867A (tr)
CN (1) CN1125081C (tr)
AU (1) AU767006B2 (tr)
BR (1) BR0013840A (tr)
CA (1) CA2383638A1 (tr)
CZ (1) CZ20021227A3 (tr)
HU (1) HUP0202793A3 (tr)
IL (1) IL148380A0 (tr)
MX (1) MXPA02002489A (tr)
NO (1) NO20021135L (tr)
PL (1) PL354488A1 (tr)
TR (1) TR200200599T2 (tr)
WO (1) WO2001018052A1 (tr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR025646A1 (es) * 2000-09-13 2002-12-04 Beta Lab Sa Cepa de levaduras metilotroficas recombinantes productoras de un precursor de insulina, construcciones de adn y metodo para obtener la cepa.
US7833513B2 (en) 2004-12-03 2010-11-16 Rhode Island Hospital Treatment of Alzheimer's Disease
DK2831262T3 (en) 2012-03-29 2018-05-28 Biocon Ltd SECRETION OF FUNCTIONAL INSULIN GLARGIN DIRECTLY IN THE CULTIVATION MEDIUM THROUGH INTRACELLULAR OVERPRESSION OF KEX2P
CN102703552B (zh) * 2012-05-15 2014-10-29 山东阿华生物药业有限公司 重组人胰岛素的制备方法及其产品
CN102816819B (zh) * 2012-08-13 2014-10-29 山东阿华生物药业有限公司 提高人胰岛素前体融合蛋白酶切转换成b30缺苏氨酸人胰岛素产率的方法
EP3939605A1 (en) * 2016-12-09 2022-01-19 Akston Biosciences Corporation Insulin-fc fusions and methods of use
EP3841106A4 (en) 2018-08-20 2022-08-10 Biocon Biologics Limited CHROMATOGRAPHY METHOD FOR PURIFYING INSULIN ANALOGS

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3033127A1 (de) 1980-09-03 1982-04-08 Hoechst Ag, 6000 Frankfurt Neue analoga des insulins
DK58285D0 (da) 1984-05-30 1985-02-08 Novo Industri As Peptider samt fremstilling og anvendelse deraf
PH25772A (en) * 1985-08-30 1991-10-18 Novo Industri As Insulin analogues, process for their preparation
DE3717370A1 (de) * 1987-05-22 1988-12-01 Hoechst Ag Mischkristalle aus insulin und insulinderivaten, verfahren zur herstellung dieser mischkristalle, diese mischkristalle enthaltende pharmazeutische mittel und ihre verwendung zur behandlung von diabetes mellitus
NZ232375A (en) * 1989-02-09 1992-04-28 Lilly Co Eli Insulin analogues modified at b29
WO1994014461A1 (en) * 1992-12-18 1994-07-07 Eli Lilly And Company Insulin analogs
CN1044856C (zh) 1993-10-19 1999-09-01 中国科学院上海有机化学研究所 果聚糖同系混合物的药物、生产方法及其用途
AR002976A1 (es) 1995-03-31 1998-05-27 Lilly Co Eli Formulaciones farmaceuticas parenterales de efecto prolongado de insulina; cristales de dichos analogos aplicables en dichas formulaciones yprocedimiento de las formulaciones mencionadas
CN1241942C (zh) * 1998-02-23 2006-02-15 纽罗克里恩生物科学有限公司 使用胰岛素的肽类似物治疗糖尿病的方法

Also Published As

Publication number Publication date
PL354488A1 (en) 2004-01-26
CN1287124A (zh) 2001-03-14
AU7430500A (en) 2001-04-10
WO2001018052A1 (en) 2001-03-15
CN1125081C (zh) 2003-10-22
NO20021135D0 (no) 2002-03-07
JP2003525867A (ja) 2003-09-02
HUP0202793A3 (en) 2005-07-28
EP1210369A1 (en) 2002-06-05
HUP0202793A2 (hu) 2002-12-28
BR0013840A (pt) 2002-07-02
CZ20021227A3 (cs) 2002-07-17
CA2383638A1 (en) 2001-03-15
IL148380A0 (en) 2002-09-12
US6800606B1 (en) 2004-10-05
AU767006B2 (en) 2003-10-30
NO20021135L (no) 2002-03-07
MXPA02002489A (es) 2002-08-28

Similar Documents

Publication Publication Date Title
NO975513D0 (no) 3-hydroksypyridin-2-karboksylsyreamidester, fremstilling og anvendelse som legemiddel
UY24572A1 (es) Conjugados peg - interferon alfa
RS50485B (sr) Terapeutske kombinacije koje sadrže amplodipin i atorvastatin
HK1030768A1 (en) Cyclic amino acids and derivatives thereof useful as pharmaceutical agents.
NO901399L (no) Aminosyrederivater.
CY1113347T1 (el) Πεπτιδια που μειωνουν τα επιπεδα της γλυκοζης στο αιμα
MY129566A (en) A hypoallergenic composition containing tolerogenic peptides inducing oral tolerance
DE69417252T2 (de) Verbesserte immunogene zusammensetzung gegen mensliches gastrin 17
NO995891D0 (no) LH-RH peptidanaloger, anvendelser og farmasöytiske blandinger inneholdende disse
DK1019358T3 (da) 3,3-diarylpropylaminer, deres anvendelse og fremstilling
NO901033D0 (no) Aminosyrederivater.
NO992102L (no) Peptidblanding, samt farmasøytisk sammensetning og kreftvaksine som innbefatter peptidblandingen
CY1105235T1 (el) Συνθεσεις λασοφοξιφενης
WO1999008657A3 (en) Self-binding shearform compositions
DK0601154T3 (da) BPC-peptider, deres fremstilling og anvendelse
BR0108056A (pt) Preparados cosméticos com extratos waltheria indica
BR0211186A (pt) peptìdeos e uso dos mesmos no escurecimento da pele
TR200200599T2 (tr) İnsan insülini monomerik analogları.
NO912271L (no) Somatostatinpreparater, deres fremstilling og anvendelse.
NO901533L (no) Aminosyrederivater.
DE602004028266D1 (de) Angiogene peptide und ihre verwendungen
UY24780A1 (es) Composiciones farmacéuticas estabilizadas a base de quinupristina y dalfopristina y su preparación.
DE69018816D1 (de) Aminosäurederivate.
GR3015777T3 (en) Substituted amino acid amide derivatives, their preparation and use.
NL194918B (nl) SDK-peptide, en therapeutische preparaten die deze bevatten.