TR200002737T2 - Aşı kompozisyonu - Google Patents
Aşı kompozisyonuInfo
- Publication number
- TR200002737T2 TR200002737T2 TR2000/02737T TR200002737T TR200002737T2 TR 200002737 T2 TR200002737 T2 TR 200002737T2 TR 2000/02737 T TR2000/02737 T TR 2000/02737T TR 200002737 T TR200002737 T TR 200002737T TR 200002737 T2 TR200002737 T2 TR 200002737T2
- Authority
- TR
- Turkey
- Prior art keywords
- hib
- prepared
- vaccine composition
- combination
- antigene
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 201000005702 Pertussis Diseases 0.000 abstract 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 abstract 1
- 229910052782 aluminium Inorganic materials 0.000 abstract 1
- 238000007429 general method Methods 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/295—Polyvalent viral antigens; Mixtures of viral and bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0016—Combination vaccines based on diphtheria-tetanus-pertussis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/05—Actinobacteria, e.g. Actinomyces, Streptomyces, Nocardia, Bifidobacterium, Gardnerella, Corynebacterium; Propionibacterium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/125—Picornaviridae, e.g. calicivirus
- A61K39/13—Poliovirus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32611—Poliovirus
- C12N2770/32634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Bu bulus,gerek hazirliksiz yapilmis gerekse sivi Hib/DTPa kombinasyon asilarinin, Hib müdahalesinden kaçinirken her bir antijenin,bunun en imünojenik oldugu alüminyum bazli kolaylastirici üzerine maksimum, kararli çekilmesini muhafaza etmek için hazirlanabildigi genel bir metotla ilgilidir. Bunu yaparken mevcut bulusa ait asilarla kombinasyon halindeki bogmaca antijenleri, en potansiyel formunda kararli bir sekilde tutulur.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9806456.1A GB9806456D0 (en) | 1998-03-25 | 1998-03-25 | Vaccine composition |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200002737T2 true TR200002737T2 (tr) | 2000-12-21 |
Family
ID=10829286
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2000/02737T TR200002737T2 (tr) | 1998-03-25 | 1999-03-22 | Aşı kompozisyonu |
Country Status (23)
Country | Link |
---|---|
EP (1) | EP1066053B8 (tr) |
JP (1) | JP2002507581A (tr) |
KR (1) | KR20010034630A (tr) |
CN (1) | CN1295481A (tr) |
AR (1) | AR014762A1 (tr) |
AT (1) | ATE335509T1 (tr) |
AU (1) | AU735619B2 (tr) |
BR (1) | BR9909037A (tr) |
CA (1) | CA2325436A1 (tr) |
CO (1) | CO4820442A1 (tr) |
CZ (1) | CZ20003536A3 (tr) |
DE (1) | DE69932709T2 (tr) |
ES (1) | ES2270590T3 (tr) |
GB (1) | GB9806456D0 (tr) |
HU (1) | HUP0101323A1 (tr) |
IL (1) | IL137999A0 (tr) |
MY (1) | MY133780A (tr) |
NO (1) | NO20004758L (tr) |
NZ (1) | NZ506604A (tr) |
PL (1) | PL343065A1 (tr) |
TR (1) | TR200002737T2 (tr) |
WO (1) | WO1999048525A1 (tr) |
ZA (1) | ZA200004956B (tr) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020054884A1 (en) | 1995-06-23 | 2002-05-09 | Smithkline Beecham Biologicals, Sa | Vaccine composition comprising a polysaccharide conjugate antigen adsorbed onto aluminium phosphate |
AU750587B2 (en) * | 1998-10-16 | 2002-07-25 | Smithkline Beecham Biologicals (Sa) | Adjuvant systems and vaccines |
EP1004314A1 (fr) * | 1998-11-26 | 2000-05-31 | Pasteur Merieux MSD | Vaccin T.d. Polio rappel pour une population vaccinée ou sensibilisée |
SK288007B6 (sk) * | 2000-06-29 | 2012-10-02 | Glaxosmithkline Biologicals S. A. | Multivalent vaccine composition, process for its producing, and its use |
GB0108364D0 (en) | 2001-04-03 | 2001-05-23 | Glaxosmithkline Biolog Sa | Vaccine composition |
KR100385711B1 (ko) * | 2000-07-05 | 2003-05-27 | 녹십자백신 주식회사 | 디프테리아, 파상풍 톡소이드와 백일해균 및b형간염표면항원을 포함한 4가 혼합백신 및 그 제조방법 |
KR100401423B1 (ko) * | 2001-01-10 | 2003-10-17 | 주식회사 엘지생명과학 | 혼합 백신의 제조 방법 |
GB0115176D0 (en) * | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
RU2323002C2 (ru) * | 2001-07-26 | 2008-04-27 | Чирон Срл. | Вакцины, содержащие алюминиевые адъюванты и гистидин |
GB0118249D0 (en) * | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
FR2828406B1 (fr) | 2001-08-08 | 2005-06-24 | Aventis Pasteur | Composition vaccinale bivalente havi |
MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
GB0220194D0 (en) * | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
GB0223355D0 (en) * | 2002-10-08 | 2002-11-13 | Chiron Spa | Vaccine |
ES2280809T3 (es) | 2002-11-01 | 2007-09-16 | Glaxosmithkline Biologicals S.A. | Composicion inmunogenica. |
GB0313916D0 (en) | 2003-06-16 | 2003-07-23 | Glaxosmithkline Biolog Sa | Vaccine composition |
CA2530434A1 (en) * | 2003-06-23 | 2005-01-06 | Aventis Pasteur, Inc. | Immunization method against neisseria meningitidis serogroups a and c |
US7867715B2 (en) | 2003-08-05 | 2011-01-11 | Alk-Abello A/S | Method of evaluating the immunological activity of a vaccine |
MXPA06008496A (es) | 2004-02-02 | 2007-01-30 | Ambrx Inc | Polipeptidos de interferon humano modificados y sus usos. |
US9931397B2 (en) | 2005-06-27 | 2018-04-03 | Glaxosmithkline Biologicals S.A. | Immunogenic composition |
EP1862176A1 (de) * | 2006-05-31 | 2007-12-05 | Rhein Biotech Gesellschaft für neue biotechnologische Prozesse und Produkte mbH | Ein Verfahren zur Herstellung einer Impfzusammensetzung |
EP1862177A1 (de) * | 2006-06-01 | 2007-12-05 | Rhein Biotech Gesellschaft für neue biotechnologische Prozesse und Produkte mbH | Ein Verfahren zur Herstellung einer Impfzusammensetzung |
PT2097102E (pt) * | 2006-09-07 | 2012-08-03 | Glaxosmithkline Biolog Sa | Vacina de combinação tendo quantidades reduzidas de antigénio de poliovírus |
GB0617602D0 (en) * | 2006-09-07 | 2006-10-18 | Glaxosmithkline Biolog Sa | Vaccine |
PE20100366A1 (es) | 2008-10-24 | 2010-05-21 | Panacea Biotec Ltd | Novedosas composiciones de vacuna con tos ferina acelular asi como el metodo para su elaboracion |
HRP20210242T4 (hr) | 2010-08-23 | 2024-05-10 | Wyeth Llc | Stabilne formulacije antigena iz bakterije neisseria meningitidis rlp2086 |
CN103096920B (zh) | 2010-09-10 | 2016-03-23 | 惠氏有限责任公司 | 脑膜炎奈瑟球菌orf2086抗原的非脂质化变体 |
CN102198270B (zh) * | 2011-05-16 | 2012-06-27 | 大连汉信生物制药有限公司 | 一种含铝佐剂乙肝疫苗的制备方法 |
EP2822584A1 (en) * | 2012-03-08 | 2015-01-14 | Novartis AG | Combination vaccines with tlr4 agonists |
SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
BR122016004924A2 (pt) | 2012-03-09 | 2019-07-30 | Pfizer Inc. | Polipeptídeo isolado e composições imunogênicas compreendendo os mesmos |
MX362793B (es) | 2013-03-08 | 2019-02-13 | Janssen Vaccines & Prevention Bv | Vacuna acelular contra pertussis. |
JP6446377B2 (ja) | 2013-03-08 | 2018-12-26 | ファイザー・インク | 免疫原性融合ポリペプチド |
CA2923129C (en) | 2013-09-08 | 2020-06-09 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
AU2016221318B2 (en) | 2015-02-19 | 2020-06-25 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
CN106075428A (zh) * | 2015-07-01 | 2016-11-09 | 北京科兴中维生物技术有限公司 | 一种免疫原性组合物及其制备方法 |
AU2018215585B2 (en) | 2017-01-31 | 2022-03-17 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
EP3655024A1 (en) | 2017-07-18 | 2020-05-27 | Serum Institute of India Private Limited | An immunogenic composition having improved stability, enhanced immunogenicity and reduced reactogenicity and process for preparation thereof |
EP3749354A4 (en) * | 2018-02-05 | 2021-11-03 | Diamyd Medical AB | NEW COMPOSITION AND ITS USE |
JOP20190242A1 (ar) | 2018-10-12 | 2020-04-12 | Serum Institute Of India Pvt Ltd | تركيبة لقاح توليفي تشمل فيروس شلل الأطفال ذو جرعة مخفّضة خاملة التنشيط وطريقة لتحضيرها |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69319728T2 (de) * | 1992-05-23 | 1999-02-04 | Smithkline Beecham Biolog | Kombinierte Impfstoffe, die Hepatitis B oberfläche Antigen und andere Antigenen enthalten |
PL184872B1 (pl) * | 1995-06-23 | 2003-01-31 | Smithkline Beecham Biolog | Kombinowana szczepionkaĆ zestaw do przygotowania kombinowanej szczepionkiĆ sposób wytwarzania kombinowanej szczepionki i jej zastosowanie |
GB9611501D0 (en) * | 1996-06-03 | 1996-08-07 | Smithkline Beecham Biolog | Vaccine compositions |
-
1998
- 1998-03-25 GB GBGB9806456.1A patent/GB9806456D0/en not_active Ceased
-
1999
- 1999-03-22 CN CN99804445A patent/CN1295481A/zh active Pending
- 1999-03-22 EP EP99915692A patent/EP1066053B8/en not_active Expired - Lifetime
- 1999-03-22 AU AU34172/99A patent/AU735619B2/en not_active Ceased
- 1999-03-22 CA CA002325436A patent/CA2325436A1/en not_active Abandoned
- 1999-03-22 AT AT99915692T patent/ATE335509T1/de not_active IP Right Cessation
- 1999-03-22 CZ CZ20003536A patent/CZ20003536A3/cs unknown
- 1999-03-22 BR BR9909037-6A patent/BR9909037A/pt not_active IP Right Cessation
- 1999-03-22 PL PL99343065A patent/PL343065A1/xx unknown
- 1999-03-22 NZ NZ506604A patent/NZ506604A/xx unknown
- 1999-03-22 TR TR2000/02737T patent/TR200002737T2/tr unknown
- 1999-03-22 DE DE69932709T patent/DE69932709T2/de not_active Expired - Lifetime
- 1999-03-22 JP JP2000537572A patent/JP2002507581A/ja active Pending
- 1999-03-22 KR KR1020007010518A patent/KR20010034630A/ko not_active Application Discontinuation
- 1999-03-22 HU HU0101323A patent/HUP0101323A1/hu unknown
- 1999-03-22 ES ES99915692T patent/ES2270590T3/es not_active Expired - Lifetime
- 1999-03-22 IL IL13799999A patent/IL137999A0/xx unknown
- 1999-03-22 WO PCT/EP1999/001959 patent/WO1999048525A1/en active IP Right Grant
- 1999-03-23 MY MYPI99001093A patent/MY133780A/en unknown
- 1999-03-23 AR ARP990101271A patent/AR014762A1/es not_active Application Discontinuation
- 1999-03-25 CO CO99018131A patent/CO4820442A1/es unknown
-
2000
- 2000-09-18 ZA ZA200004956A patent/ZA200004956B/xx unknown
- 2000-09-22 NO NO20004758A patent/NO20004758L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
MY133780A (en) | 2007-11-30 |
PL343065A1 (en) | 2001-07-30 |
CN1295481A (zh) | 2001-05-16 |
ATE335509T1 (de) | 2006-09-15 |
AU3417299A (en) | 1999-10-18 |
WO1999048525A8 (en) | 1999-11-11 |
WO1999048525A1 (en) | 1999-09-30 |
EP1066053B1 (en) | 2006-08-09 |
EP1066053B8 (en) | 2006-12-13 |
DE69932709D1 (de) | 2006-09-21 |
KR20010034630A (ko) | 2001-04-25 |
AR014762A1 (es) | 2001-03-28 |
ZA200004956B (en) | 2002-02-27 |
GB9806456D0 (en) | 1998-05-27 |
ES2270590T3 (es) | 2007-04-01 |
NO20004758L (no) | 2000-11-08 |
CO4820442A1 (es) | 1999-07-28 |
NO20004758D0 (no) | 2000-09-22 |
NZ506604A (en) | 2003-02-28 |
DE69932709T2 (de) | 2007-08-16 |
BR9909037A (pt) | 2000-12-05 |
IL137999A0 (en) | 2001-10-31 |
CA2325436A1 (en) | 1999-09-30 |
EP1066053A1 (en) | 2001-01-10 |
AU735619B2 (en) | 2001-07-12 |
JP2002507581A (ja) | 2002-03-12 |
HUP0101323A1 (hu) | 2001-08-28 |
CZ20003536A3 (cs) | 2001-08-15 |
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