TR199903065T2 - Oral uygulamaya yönelik rapamisin formülasyonlari. - Google Patents
Oral uygulamaya yönelik rapamisin formülasyonlari.Info
- Publication number
- TR199903065T2 TR199903065T2 TR1999/03065T TR9903065T TR199903065T2 TR 199903065 T2 TR199903065 T2 TR 199903065T2 TR 1999/03065 T TR1999/03065 T TR 1999/03065T TR 9903065 T TR9903065 T TR 9903065T TR 199903065 T2 TR199903065 T2 TR 199903065T2
- Authority
- TR
- Turkey
- Prior art keywords
- oral administration
- rapamycin
- rapamycin formulations
- formulations
- sugar
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Bu bulus bir çekirdek ve bir seker kaplama ihtiva eden rapamisinli kati dozaj ünitesini ortaya koymakta, ve sözü geçen seker kaplama da rapamisin, bir veya daha fazla seker, ve bir veya daha fazla birlestirici madde içermektedir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US87496597A | 1997-06-13 | 1997-06-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR199903065T2 true TR199903065T2 (tr) | 2000-09-21 |
Family
ID=25364977
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR1999/03065T TR199903065T2 (tr) | 1997-06-13 | 1998-06-11 | Oral uygulamaya yönelik rapamisin formülasyonlari. |
Country Status (26)
Country | Link |
---|---|
EP (1) | EP0994697B1 (tr) |
JP (1) | JP2002504124A (tr) |
KR (1) | KR20010013650A (tr) |
CN (1) | CN1133424C (tr) |
AR (1) | AR012971A1 (tr) |
AT (1) | ATE283687T1 (tr) |
AU (1) | AU743584B2 (tr) |
BR (1) | BR9810746A (tr) |
CA (1) | CA2293793C (tr) |
CZ (1) | CZ295276B6 (tr) |
DE (1) | DE69827947T2 (tr) |
DK (1) | DK0994697T3 (tr) |
ES (1) | ES2232948T3 (tr) |
HU (1) | HUP0003341A3 (tr) |
IL (1) | IL132986A0 (tr) |
NO (1) | NO996044D0 (tr) |
NZ (1) | NZ501652A (tr) |
PL (1) | PL337320A1 (tr) |
PT (1) | PT994697E (tr) |
RU (1) | RU2184541C2 (tr) |
SK (1) | SK284472B6 (tr) |
TR (1) | TR199903065T2 (tr) |
TW (1) | TW574040B (tr) |
UA (1) | UA65573C2 (tr) |
WO (1) | WO1998056358A1 (tr) |
ZA (1) | ZA985095B (tr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH686761A5 (de) | 1993-05-27 | 1996-06-28 | Sandoz Ag | Galenische Formulierungen. |
EP1709974A3 (en) * | 2000-06-16 | 2006-12-06 | Wyeth | Method of treating cardiovascular disease using rapamycin |
US6670355B2 (en) | 2000-06-16 | 2003-12-30 | Wyeth | Method of treating cardiovascular disease |
US20020013335A1 (en) * | 2000-06-16 | 2002-01-31 | American Home Products Corporation | Method of treating cardiovascular disease |
JP4969747B2 (ja) * | 2001-01-19 | 2012-07-04 | 武田薬品工業株式会社 | 錠剤フィルムコーティング用組成物 |
GB0123400D0 (en) | 2001-09-28 | 2001-11-21 | Novartis Ag | Organic compounds |
US20030220297A1 (en) | 2002-02-01 | 2003-11-27 | Berstein David L. | Phosphorus-containing compounds and uses thereof |
GB0602632D0 (en) * | 2006-02-08 | 2006-03-22 | Pliva Istrazivacki Inst D O O | Preparation Of A Solid Dosage From Comprising Tacrolimus And/Or Sirolimus |
CN102138903B (zh) * | 2011-03-17 | 2012-12-12 | 苏州特瑞药业有限公司 | 一种依维莫司固体口服药物组合物 |
CN110585159B (zh) * | 2019-09-12 | 2021-11-02 | 杭州华东医药集团新药研究院有限公司 | 一种含有西罗莫司的片剂 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69209183T2 (de) * | 1991-06-18 | 1996-08-08 | American Home Prod | Verwendung von Rapamycin zur Behandlung von T-Zellen Lymphom/Leukämie bei Erwachsenen |
US5352783A (en) * | 1993-06-09 | 1994-10-04 | Merck & Co., Inc. | Microbial transformation product having immunosuppressive activity |
US5536729A (en) * | 1993-09-30 | 1996-07-16 | American Home Products Corporation | Rapamycin formulations for oral administration |
IL111004A (en) * | 1993-09-30 | 1998-06-15 | American Home Prod | Oral formulations of rapamycin |
US5547948A (en) * | 1995-01-17 | 1996-08-20 | American Home Products Corporation | Controlled release of steroids from sugar coatings |
CA2230748C (en) * | 1997-03-14 | 2010-08-03 | American Home Products Corporation | Rapamycin formulations for oral administration |
-
1998
- 1998-06-11 PT PT98926557T patent/PT994697E/pt unknown
- 1998-06-11 DK DK98926557T patent/DK0994697T3/da active
- 1998-06-11 CN CNB988060965A patent/CN1133424C/zh not_active Expired - Fee Related
- 1998-06-11 WO PCT/US1998/012142 patent/WO1998056358A1/en active IP Right Grant
- 1998-06-11 AT AT98926557T patent/ATE283687T1/de not_active IP Right Cessation
- 1998-06-11 CA CA002293793A patent/CA2293793C/en not_active Expired - Fee Related
- 1998-06-11 HU HU0003341A patent/HUP0003341A3/hu unknown
- 1998-06-11 KR KR1019997011662A patent/KR20010013650A/ko active IP Right Grant
- 1998-06-11 AU AU78368/98A patent/AU743584B2/en not_active Ceased
- 1998-06-11 TR TR1999/03065T patent/TR199903065T2/tr unknown
- 1998-06-11 ZA ZA9805095A patent/ZA985095B/xx unknown
- 1998-06-11 JP JP50321399A patent/JP2002504124A/ja not_active Ceased
- 1998-06-11 NZ NZ501652A patent/NZ501652A/xx unknown
- 1998-06-11 CZ CZ19994502A patent/CZ295276B6/cs not_active IP Right Cessation
- 1998-06-11 EP EP98926557A patent/EP0994697B1/en not_active Expired - Lifetime
- 1998-06-11 AR ARP980102784A patent/AR012971A1/es unknown
- 1998-06-11 DE DE69827947T patent/DE69827947T2/de not_active Expired - Fee Related
- 1998-06-11 TW TW087109298A patent/TW574040B/zh not_active IP Right Cessation
- 1998-06-11 RU RU2000100944/14A patent/RU2184541C2/ru not_active IP Right Cessation
- 1998-06-11 SK SK1717-99A patent/SK284472B6/sk unknown
- 1998-06-11 BR BR9810746-1A patent/BR9810746A/pt active Search and Examination
- 1998-06-11 PL PL98337320A patent/PL337320A1/xx unknown
- 1998-06-11 ES ES98926557T patent/ES2232948T3/es not_active Expired - Lifetime
- 1998-06-11 IL IL13298698A patent/IL132986A0/xx unknown
- 1998-11-06 UA UA2000010192A patent/UA65573C2/uk unknown
-
1999
- 1999-12-08 NO NO996044A patent/NO996044D0/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AR012971A1 (es) | 2000-11-22 |
NO996044L (no) | 1999-12-08 |
WO1998056358A1 (en) | 1998-12-17 |
PT994697E (pt) | 2005-02-28 |
AU7836898A (en) | 1998-12-30 |
NO996044D0 (no) | 1999-12-08 |
PL337320A1 (en) | 2000-08-14 |
DE69827947D1 (de) | 2005-01-05 |
CZ295276B6 (cs) | 2005-06-15 |
JP2002504124A (ja) | 2002-02-05 |
IL132986A0 (en) | 2001-03-19 |
CZ450299A3 (cs) | 2000-08-16 |
HUP0003341A3 (en) | 2001-03-28 |
DE69827947T2 (de) | 2005-04-21 |
HUP0003341A2 (hu) | 2001-02-28 |
KR20010013650A (ko) | 2001-02-26 |
CN1133424C (zh) | 2004-01-07 |
CN1259864A (zh) | 2000-07-12 |
ZA985095B (en) | 1999-12-13 |
SK171799A3 (en) | 2000-07-11 |
ES2232948T3 (es) | 2005-06-01 |
ATE283687T1 (de) | 2004-12-15 |
DK0994697T3 (da) | 2005-02-14 |
RU2184541C2 (ru) | 2002-07-10 |
SK284472B6 (sk) | 2005-04-01 |
BR9810746A (pt) | 2000-09-19 |
UA65573C2 (uk) | 2004-04-15 |
EP0994697B1 (en) | 2004-12-01 |
EP0994697A1 (en) | 2000-04-26 |
CA2293793A1 (en) | 1998-12-17 |
CA2293793C (en) | 2006-07-11 |
TW574040B (en) | 2004-02-01 |
AU743584B2 (en) | 2002-01-31 |
NZ501652A (en) | 2001-09-28 |
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