TR199902995T2 - 9-Oksim eritromisin türevleri - Google Patents
9-Oksim eritromisin türevleriInfo
- Publication number
- TR199902995T2 TR199902995T2 TR1999/02995T TR9902995T TR199902995T2 TR 199902995 T2 TR199902995 T2 TR 199902995T2 TR 1999/02995 T TR1999/02995 T TR 1999/02995T TR 9902995 T TR9902995 T TR 9902995T TR 199902995 T2 TR199902995 T2 TR 199902995T2
- Authority
- TR
- Turkey
- Prior art keywords
- compounds
- formula
- erythromycin derivatives
- oxime erythromycin
- methods
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
Bulus, formül (I)'in bilesimleri ve onlarin farmasötik olarak uygun tuzlari ile ilgilidir, burada R1,R2,R6 ve X burada tanimlandigi gibidir. Bulus ayrica formül (I)'in bilesimlerini içeren farmasötik kompozisyonlar, bakteriyel ve protozoa enfeksiyonlarinin tedavisinde formül (I)'in sözü edilen bilesimlerini kullanma metodlari ve formül (i)'in sözü edilen bilesimlerinin hazirlanmasi için metodlar.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4934997P | 1997-06-11 | 1997-06-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR199902995T2 true TR199902995T2 (tr) | 2000-02-21 |
Family
ID=21959341
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR1999/02995T TR199902995T2 (tr) | 1997-06-11 | 1998-05-15 | 9-Oksim eritromisin türevleri |
Country Status (31)
Country | Link |
---|---|
EP (1) | EP0988308A1 (tr) |
JP (1) | JP2000513026A (tr) |
KR (1) | KR20010013660A (tr) |
CN (1) | CN1259135A (tr) |
AP (1) | AP9801253A0 (tr) |
AR (1) | AR012244A1 (tr) |
AU (1) | AU7226798A (tr) |
BG (1) | BG103947A (tr) |
BR (1) | BR9810021A (tr) |
CA (1) | CA2293335A1 (tr) |
CO (1) | CO4940506A1 (tr) |
CZ (1) | CZ9904388A3 (tr) |
EA (1) | EA199901016A1 (tr) |
GT (1) | GT199800074A (tr) |
HN (1) | HN1998000073A (tr) |
HR (1) | HRP980316A2 (tr) |
HU (1) | HUP0002252A3 (tr) |
ID (1) | ID24529A (tr) |
IL (1) | IL132767A0 (tr) |
IS (1) | IS5251A (tr) |
MA (1) | MA26505A1 (tr) |
NO (1) | NO996108L (tr) |
OA (1) | OA11225A (tr) |
PA (1) | PA8451801A1 (tr) |
PE (1) | PE79899A1 (tr) |
PL (1) | PL337606A1 (tr) |
TN (1) | TNSN98083A1 (tr) |
TR (1) | TR199902995T2 (tr) |
TW (1) | TW448174B (tr) |
WO (1) | WO1998056800A1 (tr) |
ZA (1) | ZA985018B (tr) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HN1998000159A (es) * | 1997-10-29 | 1999-02-09 | Monsanto Co | Derivados de 9- amino - 3 ceto eritromicina |
WO2000017218A1 (en) * | 1998-09-22 | 2000-03-30 | Pfizer Products Inc. | Carbamate and carbazate ketolide antibiotics |
FR2786188B1 (fr) * | 1998-11-24 | 2002-10-31 | Hoechst Marion Roussel Inc | Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments |
US6258785B1 (en) | 1998-12-02 | 2001-07-10 | Pfizer Inc. | Crystalline 9-E-(O-methyl)oxime of 11, 12-dideoxy-3-de(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribohexopyranosyloxy)-6-O-methyl-12,11-(iminocarbonyl-(2-(3-(4-(3-pyridinyl)1H-imadazol-1-yl)propyl)hydrazono))-3-oxoerythromycin |
EP1298138B1 (en) * | 1998-12-10 | 2006-11-02 | Pfizer Products Inc. | Carbamate and Carbazate Ketolide Antibiotics |
US6284732B1 (en) * | 1998-12-18 | 2001-09-04 | Bio-Rad Laboratories, Inc. | Peptides and peptide analogues designed from HFE protein and their uses in the treatment of iron overload diseases |
KR20020007374A (ko) * | 1999-04-16 | 2002-01-26 | 추후제출 | 매크롤라이드 항감염제 |
WO2000071557A1 (en) | 1999-05-24 | 2000-11-30 | Pfizer Products Inc. | 13-methyl-erythromycin derivatives |
JP2003501439A (ja) * | 1999-06-07 | 2003-01-14 | アボット・ラボラトリーズ | 6−o−カルバメートケトライド誘導体 |
ID27331A (id) * | 1999-09-29 | 2001-03-29 | Pfizer Prod Inc | Pembuatan antibiotik-antibiotik ketolida karbamat |
EP1439186A3 (en) * | 1999-12-29 | 2004-11-03 | Pfizer Products Inc. | Intermediates for novel antibacterial and prokinetic macrolides |
EP1114826A3 (en) * | 1999-12-29 | 2001-10-31 | Pfizer Products Inc. | Novel antibacterial and prokinetic macrolides |
US6946446B2 (en) | 2000-02-24 | 2005-09-20 | Abbott Laboratories | Anti-infective agents useful against multidrug-resistant strains of bacteria |
US6403776B1 (en) | 2000-07-05 | 2002-06-11 | Pfizer Inc. | Synthesis of carbamate ketolide antibiotics |
WO2003090761A1 (en) * | 2002-04-25 | 2003-11-06 | Abbott Laboratories | 9-oxime macrolide antibacterials |
AR043050A1 (es) | 2002-09-26 | 2005-07-13 | Rib X Pharmaceuticals Inc | Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos |
ES2552682T3 (es) | 2003-03-10 | 2015-12-01 | Merck Sharp & Dohme Corp. | Agentes antibacterianos novedosos |
EP2716647A3 (en) | 2004-02-27 | 2014-08-20 | Rib-X Pharmaceuticals, Inc. | Macrocyclic compounds and methods of making and using the same |
WO2009055557A1 (en) | 2007-10-25 | 2009-04-30 | Cempra Pharmaceuticals, Inc. | Process for the preparation of macrolide antibacterial agents |
WO2010048601A1 (en) | 2008-10-24 | 2010-04-29 | Cempra Pharmaceuticals, Inc. | Biodefenses using triazole-containing macrolides |
US9937194B1 (en) | 2009-06-12 | 2018-04-10 | Cempra Pharmaceuticals, Inc. | Compounds and methods for treating inflammatory diseases |
AU2010292010B2 (en) | 2009-09-10 | 2016-01-07 | Cempra Pharmaceuticals, Inc. | Methods for treating malaria, tuberculosis and MAC diseases |
CN102146085B (zh) * | 2010-02-09 | 2014-03-26 | 北京理工大学 | 一种9-肟醚酮内酯衍生物、制备方法及其药物组合物 |
SI2550286T1 (sl) | 2010-03-22 | 2016-04-29 | Cempra Pharmaceuticals, Inc. | Kristalne oblike makrolida in njihove uporabe |
RU2608390C2 (ru) | 2010-05-20 | 2017-01-18 | Семпра Фармасьютикалз, Инк. | Способы получения макролидов и кетолидов, и промежуточных соединений для их получения |
JP6042334B2 (ja) | 2010-09-10 | 2016-12-14 | センプラ ファーマシューティカルズ,インコーポレイテッド | 疾患治療のための水素結合形成フルオロケトライド |
RU2658050C2 (ru) | 2012-03-27 | 2018-06-19 | Семпра Фармасьютикалз, Инк. | Парентеральные составы для введения макролидных антибиотиков |
US9861616B2 (en) | 2013-03-14 | 2018-01-09 | Cempra Pharmaceuticals, Inc. | Methods for treating respiratory diseases and formulations therefor |
CN105188712A (zh) | 2013-03-15 | 2015-12-23 | 森普拉制药公司 | 用于制备大环内酯抗菌剂的收敛方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL114589A (en) * | 1990-11-21 | 1999-12-22 | Roussel Uclaf | Intermediates for the preparation of the history of erythromycin |
US5527780A (en) * | 1992-11-05 | 1996-06-18 | Roussel Uclaf | Erythromycin derivatives |
FR2718450B1 (fr) * | 1994-04-08 | 1997-01-10 | Roussel Uclaf | Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments. |
-
1998
- 1998-05-15 CN CN98805848A patent/CN1259135A/zh active Pending
- 1998-05-15 TR TR1999/02995T patent/TR199902995T2/tr unknown
- 1998-05-15 HU HU0002252A patent/HUP0002252A3/hu unknown
- 1998-05-15 PL PL98337606A patent/PL337606A1/xx unknown
- 1998-05-15 AU AU72267/98A patent/AU7226798A/en not_active Abandoned
- 1998-05-15 JP JP11501928A patent/JP2000513026A/ja active Pending
- 1998-05-15 CZ CZ19994388A patent/CZ9904388A3/cs unknown
- 1998-05-15 CA CA002293335A patent/CA2293335A1/en not_active Abandoned
- 1998-05-15 EA EA199901016A patent/EA199901016A1/ru unknown
- 1998-05-15 WO PCT/IB1998/000741 patent/WO1998056800A1/en not_active Application Discontinuation
- 1998-05-15 EP EP98919394A patent/EP0988308A1/en not_active Withdrawn
- 1998-05-15 IL IL13276798A patent/IL132767A0/xx unknown
- 1998-05-15 ID IDW991570A patent/ID24529A/id unknown
- 1998-05-15 BR BR9810021-1A patent/BR9810021A/pt not_active IP Right Cessation
- 1998-05-15 KR KR1019997011672A patent/KR20010013660A/ko not_active Application Discontinuation
- 1998-05-19 HN HN1998000073A patent/HN1998000073A/es unknown
- 1998-05-21 PA PA19988451801A patent/PA8451801A1/es unknown
- 1998-06-04 AP APAP/P/1998/001253A patent/AP9801253A0/en unknown
- 1998-06-05 GT GT199800074A patent/GT199800074A/es unknown
- 1998-06-08 TW TW087109086A patent/TW448174B/zh active
- 1998-06-08 PE PE1998000470A patent/PE79899A1/es not_active Application Discontinuation
- 1998-06-09 AR ARP980102703A patent/AR012244A1/es unknown
- 1998-06-10 MA MA25105A patent/MA26505A1/fr unknown
- 1998-06-10 ZA ZA9805018A patent/ZA985018B/xx unknown
- 1998-06-10 TN TNTNSN98083A patent/TNSN98083A1/fr unknown
- 1998-06-11 CO CO98033538A patent/CO4940506A1/es unknown
- 1998-06-11 HR HR60/049,349A patent/HRP980316A2/hr not_active Application Discontinuation
-
1999
- 1999-11-16 IS IS5251A patent/IS5251A/is unknown
- 1999-12-03 BG BG103947A patent/BG103947A/xx unknown
- 1999-12-03 OA OA9900269A patent/OA11225A/en unknown
- 1999-12-10 NO NO996108A patent/NO996108L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
HUP0002252A2 (hu) | 2000-12-28 |
IS5251A (is) | 1999-11-16 |
BG103947A (en) | 2000-07-31 |
IL132767A0 (en) | 2001-03-19 |
AR012244A1 (es) | 2000-09-27 |
GT199800074A (es) | 1999-11-27 |
CO4940506A1 (es) | 2000-07-24 |
ZA985018B (en) | 1999-12-10 |
TW448174B (en) | 2001-08-01 |
MA26505A1 (fr) | 2004-12-20 |
EP0988308A1 (en) | 2000-03-29 |
CA2293335A1 (en) | 1998-12-17 |
EA199901016A1 (ru) | 2000-06-26 |
PL337606A1 (en) | 2000-08-28 |
HN1998000073A (es) | 1999-01-08 |
ID24529A (id) | 2000-07-20 |
HRP980316A2 (en) | 1999-04-30 |
KR20010013660A (ko) | 2001-02-26 |
AU7226798A (en) | 1998-12-30 |
HUP0002252A3 (en) | 2002-01-28 |
JP2000513026A (ja) | 2000-10-03 |
TNSN98083A1 (fr) | 2005-03-15 |
OA11225A (en) | 2003-07-17 |
PE79899A1 (es) | 1999-08-25 |
CZ9904388A3 (cs) | 2002-10-16 |
BR9810021A (pt) | 2000-09-19 |
CN1259135A (zh) | 2000-07-05 |
NO996108D0 (no) | 1999-12-10 |
AP9801253A0 (en) | 1999-12-04 |
PA8451801A1 (es) | 2000-05-24 |
NO996108L (no) | 2000-02-10 |
WO1998056800A1 (en) | 1998-12-17 |
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