EA199901016A1 - 9-оксим-производные эритромицина - Google Patents

9-оксим-производные эритромицина

Info

Publication number
EA199901016A1
EA199901016A1 EA199901016A EA199901016A EA199901016A1 EA 199901016 A1 EA199901016 A1 EA 199901016A1 EA 199901016 A EA199901016 A EA 199901016A EA 199901016 A EA199901016 A EA 199901016A EA 199901016 A1 EA199901016 A1 EA 199901016A1
Authority
EA
Eurasian Patent Office
Prior art keywords
formula
compounds
oxym
erythromycin
derivatives
Prior art date
Application number
EA199901016A
Other languages
English (en)
Russian (ru)
Inventor
Йонг-Джин Ву
Original Assignee
Пфайзер Продактс Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пфайзер Продактс Инк. filed Critical Пфайзер Продактс Инк.
Publication of EA199901016A1 publication Critical patent/EA199901016A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
EA199901016A 1997-06-11 1998-05-15 9-оксим-производные эритромицина EA199901016A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4934997P 1997-06-11 1997-06-11
PCT/IB1998/000741 WO1998056800A1 (en) 1997-06-11 1998-05-15 9-oxime erythromycin derivatives

Publications (1)

Publication Number Publication Date
EA199901016A1 true EA199901016A1 (ru) 2000-06-26

Family

ID=21959341

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199901016A EA199901016A1 (ru) 1997-06-11 1998-05-15 9-оксим-производные эритромицина

Country Status (31)

Country Link
EP (1) EP0988308A1 (tr)
JP (1) JP2000513026A (tr)
KR (1) KR20010013660A (tr)
CN (1) CN1259135A (tr)
AP (1) AP9801253A0 (tr)
AR (1) AR012244A1 (tr)
AU (1) AU7226798A (tr)
BG (1) BG103947A (tr)
BR (1) BR9810021A (tr)
CA (1) CA2293335A1 (tr)
CO (1) CO4940506A1 (tr)
CZ (1) CZ9904388A3 (tr)
EA (1) EA199901016A1 (tr)
GT (1) GT199800074A (tr)
HN (1) HN1998000073A (tr)
HR (1) HRP980316A2 (tr)
HU (1) HUP0002252A3 (tr)
ID (1) ID24529A (tr)
IL (1) IL132767A0 (tr)
IS (1) IS5251A (tr)
MA (1) MA26505A1 (tr)
NO (1) NO996108L (tr)
OA (1) OA11225A (tr)
PA (1) PA8451801A1 (tr)
PE (1) PE79899A1 (tr)
PL (1) PL337606A1 (tr)
TN (1) TNSN98083A1 (tr)
TR (1) TR199902995T2 (tr)
TW (1) TW448174B (tr)
WO (1) WO1998056800A1 (tr)
ZA (1) ZA985018B (tr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HN1998000159A (es) * 1997-10-29 1999-02-09 Monsanto Co Derivados de 9- amino - 3 ceto eritromicina
ES2243066T3 (es) 1998-09-22 2005-11-16 Pfizer Products Inc. Antibioticos de carbamato y carbazato cetolida.
FR2786188B1 (fr) * 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
US6258785B1 (en) 1998-12-02 2001-07-10 Pfizer Inc. Crystalline 9-E-(O-methyl)oxime of 11, 12-dideoxy-3-de(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribohexopyranosyloxy)-6-O-methyl-12,11-(iminocarbonyl-(2-(3-(4-(3-pyridinyl)1H-imadazol-1-yl)propyl)hydrazono))-3-oxoerythromycin
EP1298138B1 (en) * 1998-12-10 2006-11-02 Pfizer Products Inc. Carbamate and Carbazate Ketolide Antibiotics
US6284732B1 (en) * 1998-12-18 2001-09-04 Bio-Rad Laboratories, Inc. Peptides and peptide analogues designed from HFE protein and their uses in the treatment of iron overload diseases
WO2000063224A2 (en) * 1999-04-16 2000-10-26 Kosan Biosciences, Inc. Macrolide antiinfective agents
SK15162001A3 (sk) 1999-05-24 2003-02-04 Pfizer Products Inc. Deriváty 13-metylerytromycínu
PT1181300E (pt) * 1999-06-07 2004-02-27 Abbott Lab Derivados 6-o-carbamato de cetolido
ID27331A (id) * 1999-09-29 2001-03-29 Pfizer Prod Inc Pembuatan antibiotik-antibiotik ketolida karbamat
EP1439186A3 (en) * 1999-12-29 2004-11-03 Pfizer Products Inc. Intermediates for novel antibacterial and prokinetic macrolides
EP1114826A3 (en) * 1999-12-29 2001-10-31 Pfizer Products Inc. Novel antibacterial and prokinetic macrolides
US6946446B2 (en) 2000-02-24 2005-09-20 Abbott Laboratories Anti-infective agents useful against multidrug-resistant strains of bacteria
US6403776B1 (en) 2000-07-05 2002-06-11 Pfizer Inc. Synthesis of carbamate ketolide antibiotics
WO2003090761A1 (en) * 2002-04-25 2003-11-06 Abbott Laboratories 9-oxime macrolide antibacterials
TW200420573A (en) 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
CA2529817C (en) 2003-03-10 2013-02-12 Optimer Pharmaceuticals, Inc. Novel antibacterial agents
US8202843B2 (en) 2004-02-27 2012-06-19 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same
JP5698979B2 (ja) 2007-10-25 2015-04-08 センプラ ファーマシューティカルズ，インコーポレイテッド マクロライド系抗菌剤の調製プロセス
JP5602748B2 (ja) 2008-10-24 2014-10-08 センプラ ファーマシューティカルズ，インコーポレイテッド トリアゾール含有マクロライドを用いた生体防御
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
ES2608285T3 (es) 2009-09-10 2017-04-07 Cempra Pharmaceuticals, Inc. Procedimientos para el tratamiento de paludismo, tuberculosis y enfermedades por MAC
CN102146085B (zh) * 2010-02-09 2014-03-26 北京理工大学 一种9-肟醚酮内酯衍生物、制备方法及其药物组合物
DK2550286T3 (en) 2010-03-22 2016-02-29 Cempra Pharmaceuticals Inc CRYSTALLINE FORMS OF A MACROLID AND APPLICATIONS THEREOF
BR112012029586A2 (pt) 2010-05-20 2016-08-02 Cempra Pharmaceuticals Inc processos para preparar macrolídeos e cetolídeos e intermediários dos mesmos
JP6042334B2 (ja) 2010-09-10 2016-12-14 センプラ ファーマシューティカルズ，インコーポレイテッド 疾患治療のための水素結合形成フルオロケトライド
US10188674B2 (en) 2012-03-27 2019-01-29 Cempra Pharmaceuticals, Inc. Parenteral formulations for administering macrolide antibiotics
JP6426696B2 (ja) 2013-03-14 2018-11-21 センプラ ファーマシューティカルズ，インコーポレイテッド 呼吸器疾患の治療のための方法および製剤
US9751908B2 (en) 2013-03-15 2017-09-05 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
FR2718450B1 (fr) * 1994-04-08 1997-01-10 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Also Published As

Publication number Publication date
HRP980316A2 (en) 1999-04-30
AR012244A1 (es) 2000-09-27
BR9810021A (pt) 2000-09-19
TNSN98083A1 (fr) 2005-03-15
TW448174B (en) 2001-08-01
OA11225A (en) 2003-07-17
IL132767A0 (en) 2001-03-19
CA2293335A1 (en) 1998-12-17
TR199902995T2 (tr) 2000-02-21
BG103947A (en) 2000-07-31
HUP0002252A2 (hu) 2000-12-28
EP0988308A1 (en) 2000-03-29
PL337606A1 (en) 2000-08-28
AP9801253A0 (en) 1999-12-04
IS5251A (is) 1999-11-16
CO4940506A1 (es) 2000-07-24
CZ9904388A3 (cs) 2002-10-16
WO1998056800A1 (en) 1998-12-17
HUP0002252A3 (en) 2002-01-28
AU7226798A (en) 1998-12-30
GT199800074A (es) 1999-11-27
PE79899A1 (es) 1999-08-25
PA8451801A1 (es) 2000-05-24
HN1998000073A (es) 1999-01-08
ZA985018B (en) 1999-12-10
KR20010013660A (ko) 2001-02-26
CN1259135A (zh) 2000-07-05
MA26505A1 (fr) 2004-12-20
ID24529A (id) 2000-07-20
JP2000513026A (ja) 2000-10-03
NO996108D0 (no) 1999-12-10
NO996108L (no) 2000-02-10

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