TR199902192T2 - Anti-CDL40 bile�iklerinin tedavi ama�l� uygulama y�ntemleri - Google Patents
Anti-CDL40 bile�iklerinin tedavi ama�l� uygulama y�ntemleriInfo
- Publication number
- TR199902192T2 TR199902192T2 TR1999/02192T TR9902192T TR199902192T2 TR 199902192 T2 TR199902192 T2 TR 199902192T2 TR 1999/02192 T TR1999/02192 T TR 1999/02192T TR 9902192 T TR9902192 T TR 9902192T TR 199902192 T2 TR199902192 T2 TR 199902192T2
- Authority
- TR
- Turkey
- Prior art keywords
- compounds
- cdl40
- therapeutic administration
- administration methods
- methods
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2875—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Transplantation (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3467297P | 1997-01-10 | 1997-01-10 | |
| US4015497P | 1997-03-07 | 1997-03-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR199902192T2 true TR199902192T2 (xx) | 1999-12-21 |
Family
ID=26711241
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR1999/02192T TR199902192T2 (xx) | 1997-01-10 | 1998-01-09 | Anti-CDL40 bile�iklerinin tedavi ama�l� uygulama y�ntemleri |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US20020071840A1 (https=) |
| EP (1) | EP0966302B1 (https=) |
| JP (1) | JP2001508450A (https=) |
| KR (2) | KR20000070035A (https=) |
| CN (1) | CN1248921A (https=) |
| AT (1) | ATE356634T1 (https=) |
| AU (1) | AU721697B2 (https=) |
| BR (1) | BR9807471A (https=) |
| CA (1) | CA2277223A1 (https=) |
| CZ (1) | CZ244399A3 (https=) |
| DE (1) | DE69837322T2 (https=) |
| EA (1) | EA001426B1 (https=) |
| EE (1) | EE9900275A (https=) |
| IL (1) | IL130785A0 (https=) |
| IS (1) | IS5101A (https=) |
| NO (1) | NO993275L (https=) |
| NZ (1) | NZ337073A (https=) |
| PL (1) | PL193966B1 (https=) |
| TR (1) | TR199902192T2 (https=) |
| WO (1) | WO1998030241A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5474771A (en) | 1991-11-15 | 1995-12-12 | The Trustees Of Columbia University In The City Of New York | Murine monoclonal antibody (5c8) recognizes a human glycoprotein on the surface of T-lymphocytes, compositions containing same |
| US7070777B1 (en) | 1991-11-15 | 2006-07-04 | The Trustees Of Columbia University In The City Of New York | Method for inhibiting inflammation with an antibody that binds the 5C8 protein |
| US6340459B1 (en) | 1995-12-01 | 2002-01-22 | The Trustees Of Columbia University In The City Of New York | Therapeutic applications for the anti-T-BAM (CD40-L) monoclonal antibody 5C8 in the treatment of reperfusion injury in non-transplant recipients |
| BR9809641A (pt) * | 1997-05-17 | 2000-07-11 | Biogen Inc | Uso de um interruptor de ligação cd40:cd154 para evitar respostas imunes inadaptadas, particularmente rejeição a enxerto |
| CN1261285A (zh) * | 1997-06-20 | 2000-07-26 | 拜奥根有限公司 | 治疗性蛋白抑制剂综合症的cd154阻断治疗 |
| NZ511034A (en) * | 1998-09-21 | 2004-03-26 | American Nat Red Cross | Methods of downmodulating the immune response to therapeutic proteins |
| WO2000072882A1 (fr) * | 1999-06-01 | 2000-12-07 | Eisai Co., Ltd. | Agents prophylactiques du purpura thrombocytopenique idiopathique |
| GB9927757D0 (en) * | 1999-11-25 | 2000-01-26 | Kennedy Rheumatology Inst | Treatment of autoimmune diseases |
| WO2001066141A1 (fr) * | 2000-03-06 | 2001-09-13 | Eisai Co., Ltd. | Agents therapeutiques et prophylactiques diriges contre le syndrome des antiphospholipides |
| AU2001251612A1 (en) | 2000-04-14 | 2001-10-30 | Millennium Pharmaceuticals, Inc. | Roles of jak/stat family members in tolerance induction |
| US20030059427A1 (en) * | 2000-04-28 | 2003-03-27 | Force Walker R. | Isolation and characterization of highly active anti-CD40 antibody |
| CA2781858C (en) | 2000-05-12 | 2015-03-31 | Genzyme Corporation | Modulators of tnf-.alpha. signaling |
| JP3785508B2 (ja) * | 2002-04-15 | 2006-06-14 | 学校法人慶應義塾 | 遺伝子治療における免疫応答を解析できる実験モデルマウス |
| ATE520400T1 (de) * | 2002-11-21 | 2011-09-15 | Genzyme Corp | Kombination von einem diamidderivat und immunsuppressiva zur unterdrückung der transplantatabstossung |
| EP2367849B1 (en) | 2008-12-05 | 2017-11-01 | ALS Therapy Development Institute | Method for the treatment of neurodegenerative diseases |
| WO2025117849A1 (en) | 2023-11-28 | 2025-06-05 | Eledon Pharmaceuticals, Inc. | Methods and compositions for prevention of transplant rejection |
| WO2025235683A1 (en) | 2024-05-07 | 2025-11-13 | Eledon Pharmaceuticals, Inc. | Methods and compositions for prevention of transplant rejection |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5981724A (en) * | 1991-10-25 | 1999-11-09 | Immunex Corporation | DNA encoding CD40 ligand, a cytokine that binds CD40 |
| US5962406A (en) * | 1991-10-25 | 1999-10-05 | Immunex Corporation | Recombinant soluble CD40 ligand polypeptide and pharmaceutical composition containing the same |
| US5961974A (en) * | 1991-10-25 | 1999-10-05 | Immunex Corporation | Monoclonal antibodies to CD40 ligand, pharmaceutical composition comprising the same and hybridomas producing the same |
| US5474771A (en) * | 1991-11-15 | 1995-12-12 | The Trustees Of Columbia University In The City Of New York | Murine monoclonal antibody (5c8) recognizes a human glycoprotein on the surface of T-lymphocytes, compositions containing same |
| US5397703A (en) * | 1992-07-09 | 1995-03-14 | Cetus Oncology Corporation | Method for generation of antibodies to cell surface molecules |
| US5540926A (en) * | 1992-09-04 | 1996-07-30 | Bristol-Myers Squibb Company | Soluble and its use in B cell stimulation |
| US5869049A (en) * | 1993-09-02 | 1999-02-09 | Trustees Of Dartmouth College | Methods of inducing T cell unresponsiveness to bone marrow with gp39 antagonists |
| ZA946765B (en) * | 1993-09-02 | 1996-02-15 | Dartmouth College | Methods of prolonged suppression of humoral immunity |
| ES2143553T3 (es) * | 1993-09-02 | 2000-05-16 | Dartmouth College | Anticuerpos anti-gp39 y sus utilizaciones. |
| NZ273208A (en) * | 1993-09-02 | 2000-12-22 | Dartmouth College | Suppressing a humoral immune response against a thymus dependant (TD) antigen |
| ES2222463T3 (es) * | 1993-12-23 | 2005-02-01 | Immunex Corporation | Uso de anticuerpos monoclonales o ligandos oligomericos solubles en la fabricacion de un medicamento para la prevencion o tratamiento de trastornos neoplasicos. |
| US5683693A (en) * | 1994-04-25 | 1997-11-04 | Trustees Of Dartmouth College | Method for inducing T cell unresponsiveness to a tissue or organ graft with anti-CD40 ligand antibody or soluble CD40 |
| US5876950A (en) * | 1995-01-26 | 1999-03-02 | Bristol-Myers Squibb Company | Monoclonal antibodies specific for different epitopes of human GP39 and methods for their use in diagnosis and therapy |
| US5833987A (en) * | 1995-06-07 | 1998-11-10 | Trustees Of Dartmouth College | Treatment of T cell mediated autoimmune disorders |
| US6001358A (en) * | 1995-11-07 | 1999-12-14 | Idec Pharmaceuticals Corporation | Humanized antibodies to human gp39, compositions containing thereof |
| EP0892643B2 (en) * | 1996-03-20 | 2009-09-02 | Bristol-Myers Squibb Company | Methods for inhibiting an immune response by blocking the gp39/cd40 and ctla4/cd28/b7 pathways and compositions for use therewith |
-
1998
- 1998-01-09 PL PL98334500A patent/PL193966B1/pl not_active IP Right Cessation
- 1998-01-09 BR BR9807471A patent/BR9807471A/pt not_active Application Discontinuation
- 1998-01-09 DE DE69837322T patent/DE69837322T2/de not_active Expired - Fee Related
- 1998-01-09 EA EA199900633A patent/EA001426B1/ru not_active IP Right Cessation
- 1998-01-09 JP JP53122098A patent/JP2001508450A/ja not_active Ceased
- 1998-01-09 EP EP98901227A patent/EP0966302B1/en not_active Expired - Lifetime
- 1998-01-09 TR TR1999/02192T patent/TR199902192T2/xx unknown
- 1998-01-09 KR KR1019997006254A patent/KR20000070035A/ko not_active Ceased
- 1998-01-09 AU AU57353/98A patent/AU721697B2/en not_active Ceased
- 1998-01-09 IL IL13078598A patent/IL130785A0/xx unknown
- 1998-01-09 AT AT98901227T patent/ATE356634T1/de not_active IP Right Cessation
- 1998-01-09 EE EEP199900275A patent/EE9900275A/xx unknown
- 1998-01-09 CN CN98802832A patent/CN1248921A/zh active Pending
- 1998-01-09 KR KR1020057013115A patent/KR100632846B1/ko not_active Expired - Fee Related
- 1998-01-09 CA CA002277223A patent/CA2277223A1/en not_active Abandoned
- 1998-01-09 CZ CZ992443A patent/CZ244399A3/cs unknown
- 1998-01-09 WO PCT/US1998/000573 patent/WO1998030241A1/en not_active Ceased
- 1998-01-09 NZ NZ337073A patent/NZ337073A/xx unknown
-
1999
- 1999-06-30 IS IS5101A patent/IS5101A/is unknown
- 1999-07-01 NO NO993275A patent/NO993275L/no not_active Application Discontinuation
-
2001
- 2001-12-12 US US10/015,832 patent/US20020071840A1/en not_active Abandoned
-
2004
- 2004-12-23 US US11/021,599 patent/US20050158314A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20050158314A1 (en) | 2005-07-21 |
| CA2277223A1 (en) | 1998-07-16 |
| KR20050088494A (ko) | 2005-09-06 |
| CZ244399A3 (cs) | 1999-10-13 |
| CN1248921A (zh) | 2000-03-29 |
| PL334500A1 (en) | 2000-02-28 |
| EE9900275A (et) | 2000-02-15 |
| KR100632846B1 (ko) | 2006-10-16 |
| WO1998030241A1 (en) | 1998-07-16 |
| AU721697B2 (en) | 2000-07-13 |
| DE69837322D1 (de) | 2007-04-26 |
| EA001426B1 (ru) | 2001-02-26 |
| BR9807471A (pt) | 2000-03-21 |
| DE69837322T2 (de) | 2007-11-22 |
| KR20000070035A (ko) | 2000-11-25 |
| JP2001508450A (ja) | 2001-06-26 |
| EP0966302B1 (en) | 2007-03-14 |
| AU5735398A (en) | 1998-08-03 |
| US20020071840A1 (en) | 2002-06-13 |
| HK1024424A1 (en) | 2000-10-13 |
| PL193966B1 (pl) | 2007-04-30 |
| EP0966302A1 (en) | 1999-12-29 |
| EA199900633A1 (ru) | 2000-02-28 |
| IS5101A (is) | 1999-06-30 |
| NZ337073A (en) | 2001-01-26 |
| IL130785A0 (en) | 2001-01-28 |
| NO993275D0 (no) | 1999-07-01 |
| ATE356634T1 (de) | 2007-04-15 |
| NO993275L (no) | 1999-09-09 |
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