TR199902191T2 - Anti-CD40L bilesikleri ile lupus nefritis tedavisi - Google Patents
Anti-CD40L bilesikleri ile lupus nefritis tedavisiInfo
- Publication number
- TR199902191T2 TR199902191T2 TR1999/02191T TR9902191T TR199902191T2 TR 199902191 T2 TR199902191 T2 TR 199902191T2 TR 1999/02191 T TR1999/02191 T TR 1999/02191T TR 9902191 T TR9902191 T TR 9902191T TR 199902191 T2 TR199902191 T2 TR 199902191T2
- Authority
- TR
- Turkey
- Prior art keywords
- cd40l compounds
- lupus nephritis
- immune complex
- cd40l
- compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
Immün kompleks hastaliklarla baglantili nefriti anti-CD40L bilesikleriyle tedaviye yönelik yöntemler öngörülmektedir. Teskil örneklerinden birinde immün kompleks hastaligi olan böbrek allografti yapilmis bir hastaya, nakil yapilan böbrek içinde immün kompleks glomerülonefrit olusmasini önlemek için anti CD40L bilesikleri verilmistir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3467397P | 1997-01-10 | 1997-01-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR199902191T2 true TR199902191T2 (tr) | 1999-12-21 |
Family
ID=21877889
Family Applications (7)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2000/01248T TR200001248T2 (tr) | 1997-01-10 | 1997-12-31 | Anti-CD40L bileşikleri ile lupus nefritis tedavisi |
TR2000/01250T TR200001250T2 (tr) | 1997-01-10 | 1997-12-31 | Ati-CD40L bileşikleri ile lupus nefritis tedavisi |
TR1999/02191T TR199902191T2 (tr) | 1997-01-10 | 1997-12-31 | Anti-CD40L bilesikleri ile lupus nefritis tedavisi |
TR2000/01246T TR200001246T2 (tr) | 1997-01-10 | 1997-12-31 | Anti-CD40L bileşikleri ile lupus nefritis tedavisi |
TR2000/01247T TR200001247T2 (tr) | 1997-01-10 | 1997-12-31 | Anti-CD40L bileşikleri ile lupus nefritis tedavisi. |
TR2000/01249T TR200001249T2 (tr) | 1997-01-10 | 1997-12-31 | Anti-CD40L bileşikleri ile lupus nefritis tedavisi |
TR2000/01251T TR200001251T2 (tr) | 1997-01-10 | 1997-12-31 | Anti-CD40L bileşikleri ile lupus nefritis tedavisi |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2000/01248T TR200001248T2 (tr) | 1997-01-10 | 1997-12-31 | Anti-CD40L bileşikleri ile lupus nefritis tedavisi |
TR2000/01250T TR200001250T2 (tr) | 1997-01-10 | 1997-12-31 | Ati-CD40L bileşikleri ile lupus nefritis tedavisi |
Family Applications After (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2000/01246T TR200001246T2 (tr) | 1997-01-10 | 1997-12-31 | Anti-CD40L bileşikleri ile lupus nefritis tedavisi |
TR2000/01247T TR200001247T2 (tr) | 1997-01-10 | 1997-12-31 | Anti-CD40L bileşikleri ile lupus nefritis tedavisi. |
TR2000/01249T TR200001249T2 (tr) | 1997-01-10 | 1997-12-31 | Anti-CD40L bileşikleri ile lupus nefritis tedavisi |
TR2000/01251T TR200001251T2 (tr) | 1997-01-10 | 1997-12-31 | Anti-CD40L bileşikleri ile lupus nefritis tedavisi |
Country Status (19)
Country | Link |
---|---|
US (2) | US20030031668A1 (tr) |
EP (2) | EP0948355A1 (tr) |
JP (1) | JP2001508441A (tr) |
KR (2) | KR100618081B1 (tr) |
CN (2) | CN1247472A (tr) |
AU (1) | AU5709798A (tr) |
BR (1) | BR9714523A (tr) |
CA (1) | CA2277222A1 (tr) |
CZ (1) | CZ297680B6 (tr) |
EA (2) | EA200501076A1 (tr) |
EE (1) | EE9900273A (tr) |
HU (1) | HUP0000833A3 (tr) |
IL (1) | IL130784A0 (tr) |
IS (1) | IS5100A (tr) |
NO (1) | NO993274L (tr) |
NZ (1) | NZ337072A (tr) |
PL (1) | PL190663B1 (tr) |
TR (7) | TR200001248T2 (tr) |
WO (1) | WO1998030240A1 (tr) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5474771A (en) | 1991-11-15 | 1995-12-12 | The Trustees Of Columbia University In The City Of New York | Murine monoclonal antibody (5c8) recognizes a human glycoprotein on the surface of T-lymphocytes, compositions containing same |
US7070777B1 (en) | 1991-11-15 | 2006-07-04 | The Trustees Of Columbia University In The City Of New York | Method for inhibiting inflammation with an antibody that binds the 5C8 protein |
CA2089229C (en) | 1992-02-14 | 2010-04-13 | Alejandro A. Aruffo | Cd40cr receptor and ligands therefor |
US6340459B1 (en) | 1995-12-01 | 2002-01-22 | The Trustees Of Columbia University In The City Of New York | Therapeutic applications for the anti-T-BAM (CD40-L) monoclonal antibody 5C8 in the treatment of reperfusion injury in non-transplant recipients |
EP1067954A4 (en) * | 1998-04-03 | 2004-08-18 | Dartmouth College | USE OF ANTI-GP39 ANTIBODIES FOR TREATING AND / OR REGRESSING LUPUS AND RELATED KIDNEY DISEASE |
IL126681A0 (en) * | 1998-10-21 | 1999-08-17 | Opperbas Holding Bv | Treatment of trauma-related conditions |
US7553487B2 (en) | 1998-12-14 | 2009-06-30 | Genetics Institute, Llc | Method and compositions for treating asthma |
MXPA01006006A (es) | 1998-12-14 | 2004-08-12 | Genetics Inst | Cadena receptora de citocina. |
US6171795B1 (en) * | 1999-07-29 | 2001-01-09 | Nexstar Pharmaceuticals, Inc. | Nucleic acid ligands to CD40ligand |
AU2001249182A1 (en) * | 2000-03-14 | 2001-09-24 | Genetics Institute Inc. | Use of rapamycin and agents that inhibit b7 activity in immunomodulation |
AU8867501A (en) * | 2000-09-01 | 2002-03-13 | Biogen Inc | Co-crystal structure of monoclonal antibody 5c8 and cd154, and use thereof in drug design |
CA2422076A1 (en) * | 2000-09-18 | 2002-03-21 | Idec Pharmaceutical Corporation | Combination therapy for treatment of autoimmune diseases using b cell depleting/immunoregulatory antibody combination |
JP4943161B2 (ja) | 2003-12-23 | 2012-05-30 | ジェネンテック, インコーポレイテッド | 新規抗il13モノクローナル抗体での癌の処置 |
AR049390A1 (es) | 2004-06-09 | 2006-07-26 | Wyeth Corp | Anticuerpos contra la interleuquina-13 humana y usos de los mismos |
US7501121B2 (en) | 2004-06-17 | 2009-03-10 | Wyeth | IL-13 binding agents |
CN100369932C (zh) * | 2005-04-07 | 2008-02-20 | 苏州大学 | 抗人cd154单克隆抗体及其应用 |
US9044459B2 (en) | 2008-12-05 | 2015-06-02 | Als Therapy Development Institute | Method for the treatment of neurodegenerative diseases |
JP2012511014A (ja) | 2008-12-05 | 2012-05-17 | エイエルエス・セラピー・デベロップメント・インスティテュート | 神経変成疾患を治療する方法 |
US20130310266A1 (en) * | 2010-09-03 | 2013-11-21 | Immport Therapeutics, Inc. | Methods and Compositions For The Diagnosis And Treatment Of Cancer and Autoimmune Disorders |
NZ756749A (en) | 2013-09-13 | 2022-05-27 | Genentech Inc | Methods and compositions comprising purified recombinant polypeptides |
RU2016107435A (ru) | 2013-09-13 | 2017-10-18 | Дженентек, Инк. | Композиции и способы обнаружения и количественного определения белка клеток-хозяев в клеточных линиях и рекомбинантные полипептидные продукты |
JP2017525370A (ja) | 2014-08-21 | 2017-09-07 | ザ ジェネラル ホスピタル コーポレイション | 腫瘍壊死因子スーパーファミリーおよびtnf様リガンドムテインならびに腫瘍壊死因子スーパーファミリーおよびtnf様リガンドムテインを調製および使用する方法 |
MA41459A (fr) | 2015-02-03 | 2017-12-12 | Als Therapy Development Inst | Anticorps anti-cd40l et méthodes pour traiter des maladies ou des troubles liés aux cd40l |
JP2018526443A (ja) * | 2015-08-31 | 2018-09-13 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung | 全身性エリテマトーデスを治療するためのlgals3bpの調節方法 |
AU2018271915A1 (en) | 2017-05-24 | 2019-11-28 | Als Therapy Development Institute | Therapeutic anti-CD40 ligand antibodies |
KR20210095781A (ko) | 2020-01-24 | 2021-08-03 | 주식회사 에이프릴바이오 | 항원결합 단편 및 생리활성 이펙터 모이어티로 구성된 융합 컨스트럭트를 포함하는 다중결합항체 및 이를 포함하는 약학조성물 |
EP4288455A1 (en) | 2021-02-03 | 2023-12-13 | Mozart Therapeutics, Inc. | Binding agents and methods of using the same |
WO2023076876A1 (en) | 2021-10-26 | 2023-05-04 | Mozart Therapeutics, Inc. | Modulation of immune responses to viral vectors |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5474771A (en) * | 1991-11-15 | 1995-12-12 | The Trustees Of Columbia University In The City Of New York | Murine monoclonal antibody (5c8) recognizes a human glycoprotein on the surface of T-lymphocytes, compositions containing same |
US5876950A (en) * | 1995-01-26 | 1999-03-02 | Bristol-Myers Squibb Company | Monoclonal antibodies specific for different epitopes of human GP39 and methods for their use in diagnosis and therapy |
US6440418B1 (en) * | 1995-11-07 | 2002-08-27 | Idec Pharmaceuticals Corporation | Methods of treating autoimmune diseases with gp39-specific antibodies |
AU1748897A (en) * | 1996-01-16 | 1997-08-11 | Biogen, Inc. | Therapeutic applications of T-BAM (CD40-L) technology to treat inflammatory kidney diseases |
WO1997034473A1 (en) * | 1996-03-21 | 1997-09-25 | The Trustees Of Columbia University In The City Of New York | Craf1 (traf-3) isoforms and uses thereof |
-
1997
- 1997-12-31 EA EA200501076A patent/EA200501076A1/ru unknown
- 1997-12-31 CN CN97181948A patent/CN1247472A/zh active Pending
- 1997-12-31 CZ CZ0244499A patent/CZ297680B6/cs not_active IP Right Cessation
- 1997-12-31 EE EEP199900273A patent/EE9900273A/xx unknown
- 1997-12-31 EP EP97953325A patent/EP0948355A1/en not_active Withdrawn
- 1997-12-31 CN CNA2004100353620A patent/CN1572325A/zh active Pending
- 1997-12-31 JP JP53090198A patent/JP2001508441A/ja not_active Ceased
- 1997-12-31 TR TR2000/01248T patent/TR200001248T2/tr unknown
- 1997-12-31 NZ NZ337072A patent/NZ337072A/xx unknown
- 1997-12-31 TR TR2000/01250T patent/TR200001250T2/tr unknown
- 1997-12-31 KR KR1020057013113A patent/KR100618081B1/ko not_active IP Right Cessation
- 1997-12-31 IL IL13078497A patent/IL130784A0/xx unknown
- 1997-12-31 TR TR1999/02191T patent/TR199902191T2/tr unknown
- 1997-12-31 CA CA002277222A patent/CA2277222A1/en not_active Abandoned
- 1997-12-31 TR TR2000/01246T patent/TR200001246T2/tr unknown
- 1997-12-31 EP EP03014404A patent/EP1357131A3/en not_active Withdrawn
- 1997-12-31 EA EA199900636A patent/EA006314B1/ru not_active IP Right Cessation
- 1997-12-31 HU HU0000833A patent/HUP0000833A3/hu unknown
- 1997-12-31 BR BR9714523-8A patent/BR9714523A/pt not_active Application Discontinuation
- 1997-12-31 TR TR2000/01247T patent/TR200001247T2/tr unknown
- 1997-12-31 PL PL97334495A patent/PL190663B1/pl not_active IP Right Cessation
- 1997-12-31 TR TR2000/01249T patent/TR200001249T2/tr unknown
- 1997-12-31 WO PCT/US1997/023482 patent/WO1998030240A1/en active IP Right Grant
- 1997-12-31 AU AU57097/98A patent/AU5709798A/en not_active Abandoned
- 1997-12-31 KR KR1019997006253A patent/KR20000070034A/ko not_active Application Discontinuation
- 1997-12-31 TR TR2000/01251T patent/TR200001251T2/tr unknown
-
1999
- 1999-06-30 IS IS5100A patent/IS5100A/is unknown
- 1999-07-01 NO NO993274A patent/NO993274L/no not_active Application Discontinuation
-
2002
- 2002-09-27 US US10/260,639 patent/US20030031668A1/en not_active Abandoned
-
2006
- 2006-09-25 US US11/527,700 patent/US20070190053A1/en not_active Abandoned
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