TR199800347T1 - �la� uygulamas� i�in insan derisinin mikro-g�zeneklendirilmesi ve uygulamalar�n g�zlemlenmesi. - Google Patents

�la� uygulamas� i�in insan derisinin mikro-g�zeneklendirilmesi ve uygulamalar�n g�zlemlenmesi.

Info

Publication number
TR199800347T1
TR199800347T1 TR1998/00347T TR9800347T TR199800347T1 TR 199800347 T1 TR199800347 T1 TR 199800347T1 TR 1998/00347 T TR1998/00347 T TR 1998/00347T TR 9800347 T TR9800347 T TR 9800347T TR 199800347 T1 TR199800347 T1 TR 199800347T1
Authority
TR
Turkey
Prior art keywords
corneum
startum
micro
poring
sonic energy
Prior art date
Application number
TR1998/00347T
Other languages
English (en)
Turkish (tr)
Inventor
A. Eppstein Jonathan
R. Hatch Michael
Yang Difei
Original Assignee
Spectrx, Inc.
Altea Technologies, Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spectrx, Inc., Altea Technologies, Inc filed Critical Spectrx, Inc.
Publication of TR199800347T1 publication Critical patent/TR199800347T1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14507Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045Devices for taking samples of body liquids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0047Sonopheresis, i.e. ultrasonically-enhanced transdermal delivery, electroporation of a pharmacologically active agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B17/3203Fluid jet cutting instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/203Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser applying laser energy to the outside of the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00017Electrical control of surgical instruments
    • A61B2017/00137Details of operation mode
    • A61B2017/00154Details of operation mode pulsed
    • A61B2017/00172Pulse trains, bursts, intermittent continuous operation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743Type of operation; Specification of treatment sites
    • A61B2017/00747Dermatology
    • A61B2017/00761Removing layer of skin tissue, e.g. wrinkles, scars or cancerous tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743Type of operation; Specification of treatment sites
    • A61B2017/00747Dermatology
    • A61B2017/00765Decreasing the barrier function of skin tissue by radiated energy, e.g. using ultrasound, using laser for skin perforation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00452Skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00452Skin
    • A61B2018/0047Upper parts of the skin, e.g. skin peeling or treatment of wrinkles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Surgical Instruments (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Laser Surgery Devices (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TR1998/00347T 1995-08-29 1996-08-29 �la� uygulamas� i�in insan derisinin mikro-g�zeneklendirilmesi ve uygulamalar�n g�zlemlenmesi. TR199800347T1 (xx)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52054795A 1995-08-29 1995-08-29
US804395P 1995-10-30 1995-10-30

Publications (1)

Publication Number Publication Date
TR199800347T1 true TR199800347T1 (xx) 1998-05-21

Family

ID=26677684

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1998/00347T TR199800347T1 (xx) 1995-08-29 1996-08-29 �la� uygulamas� i�in insan derisinin mikro-g�zeneklendirilmesi ve uygulamalar�n g�zlemlenmesi.

Country Status (14)

Country Link
EP (1) EP0858285A4 (fr)
JP (2) JP3899427B2 (fr)
CN (1) CN1174713C (fr)
AU (1) AU707065B2 (fr)
BR (1) BR9610012A (fr)
CA (1) CA2199002C (fr)
ES (1) ES2536459T3 (fr)
GB (1) GB2307414B (fr)
HK (1) HK1009321A1 (fr)
IL (1) IL123379A (fr)
NO (1) NO334437B1 (fr)
PT (1) PT1563788E (fr)
TR (1) TR199800347T1 (fr)
WO (1) WO1997007734A1 (fr)

Families Citing this family (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6315772B1 (en) * 1993-09-24 2001-11-13 Transmedica International, Inc. Laser assisted pharmaceutical delivery and fluid removal
DK0914178T3 (da) 1996-06-18 2003-04-22 Alza Corp Anordning til forøgelse af transdermal afgivelse eller prøveudtagning af et middel
ES2200187T3 (es) * 1996-07-03 2004-03-01 Altea Therapeutics Corporation Microporacion mecanica multiple de la piel o de la mucosa.
CA2265906C (fr) * 1996-09-17 2003-11-11 Deka Products Limited Partnership Systeme d'administration de medicaments par transport
US20060002949A1 (en) 1996-11-14 2006-01-05 Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. Transcutaneous immunization without heterologous adjuvant
EP0952850A2 (fr) * 1996-12-31 1999-11-03 Altea Technologies, Inc. Formation de micropores sur un tissu pour l'administration d'agents bioactifs
US6527716B1 (en) 1997-12-30 2003-03-04 Altea Technologies, Inc. Microporation of tissue for delivery of bioactive agents
US6027496A (en) 1997-03-25 2000-02-22 Abbott Laboratories Removal of stratum corneum by means of light
CA2306728A1 (fr) 1997-10-21 1999-04-29 Abbott Laboratories Appareil et procede pour la collecte de fluides interstitiels
US6155992A (en) * 1997-12-02 2000-12-05 Abbott Laboratories Method and apparatus for obtaining interstitial fluid for diagnostic tests
US6918901B1 (en) 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
PT1037686E (pt) * 1997-12-11 2005-10-31 Alza Corp Aparelho para potenciar o fluxo de agente transdermico
DE69806963T2 (de) * 1997-12-11 2002-11-21 Alza Corp Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses
KR100557261B1 (ko) 1997-12-11 2006-03-07 알자 코포레이션 경피성 작용제 유동률을 증진시키기 위한 장치
WO1999044508A1 (fr) * 1998-03-06 1999-09-10 Spectrx, Inc. Dispositif integre de formation de micropores, de prelevement et d'analyse et procede associe
US6173202B1 (en) * 1998-03-06 2001-01-09 Spectrx, Inc. Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue
US6530915B1 (en) 1998-03-06 2003-03-11 Spectrx, Inc. Photothermal structure for biomedical applications, and method therefor
US6091975A (en) * 1998-04-01 2000-07-18 Alza Corporation Minimally invasive detecting device
US6569157B1 (en) * 1998-05-18 2003-05-27 Abbott Laboratories Removal of stratum corneum by means of light
US6503231B1 (en) 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
US7344499B1 (en) 1998-06-10 2008-03-18 Georgia Tech Research Corporation Microneedle device for extraction and sensing of bodily fluids
US6077660A (en) * 1998-06-10 2000-06-20 Abbott Laboratories Diagnostic assay requiring a small sample of biological fluid
EP1987854A1 (fr) 1998-07-14 2008-11-05 Altea Therapeutics Corporation Elimination contrôlée d'une membrane biologique par une charge pyrotechnique en vue d'un transport transmembranaire
BR9912333A (pt) * 1998-07-21 2001-04-17 Spectrx Inc Sistema para monitorar continuamente uma caracterìstica de um fluido biológico extraìdo de um organismo e processo para extrair um fluido biológico de uma membrana biológica de um organismo e monitorar continuamente uma caracterìstica do mesmo.
US7384396B2 (en) 1998-07-21 2008-06-10 Spectrx Inc. System and method for continuous analyte monitoring
NZ510923A (en) * 1998-09-04 2003-09-26 Powderject Res Ltd Monitoring methods using particle delivery methods
US6468229B1 (en) 1998-10-20 2002-10-22 Abbott Laboratories Apparatus and method for the collection of interstitial fluids
US6708060B1 (en) 1998-11-09 2004-03-16 Transpharma Ltd. Handheld apparatus and method for transdermal drug delivery and analyte extraction
US6148232A (en) 1998-11-09 2000-11-14 Elecsys Ltd. Transdermal drug delivery and analyte extraction
US6611706B2 (en) 1998-11-09 2003-08-26 Transpharma Ltd. Monopolar and bipolar current application for transdermal drug delivery and analyte extraction
US6597946B2 (en) 1998-11-09 2003-07-22 Transpharma Ltd. Electronic card for transdermal drug delivery and analyte extraction
US6743211B1 (en) 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6611707B1 (en) 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
US6692456B1 (en) * 1999-06-08 2004-02-17 Altea Therapeutics Corporation Apparatus for microporation of biological membranes using thin film tissue interface devices, and method therefor
US20030078499A1 (en) 1999-08-12 2003-04-24 Eppstein Jonathan A. Microporation of tissue for delivery of bioactive agents
US6355054B1 (en) * 1999-11-05 2002-03-12 Ceramoptec Industries, Inc. Laser system for improved transbarrier therapeutic radiation delivery
DE19963034A1 (de) 1999-12-24 2001-06-28 Roche Diagnostics Gmbh System zur verbesserten Bestimmung des Glukosespiegels anhand von Messungen in interstitieller Flüssigkeit
IL136008A0 (en) 2000-05-07 2001-05-20 Elecsys Ltd Electrically-mediated transdermal drug injection
US7597692B2 (en) 2000-06-08 2009-10-06 Massachusetts Institute Of Technology Microscission processes and procedures
US6706032B2 (en) 2000-06-08 2004-03-16 Massachusetts Institute Of Technology Localized molecular and ionic transport to and from tissues
AUPR044000A0 (en) * 2000-09-28 2000-10-26 Norwood Abbey Ltd Diagnostic device
US6537243B1 (en) 2000-10-12 2003-03-25 Abbott Laboratories Device and method for obtaining interstitial fluid from a patient for diagnostic tests
US6882884B1 (en) 2000-10-13 2005-04-19 Soundskin, L.L.C. Process for the stimulation of production of extracellular dermal proteins in human tissue
US6733493B2 (en) * 2000-11-16 2004-05-11 Innotech Usa, Inc. Laser skin perforator
US9302903B2 (en) 2000-12-14 2016-04-05 Georgia Tech Research Corporation Microneedle devices and production thereof
US7027478B2 (en) 2000-12-21 2006-04-11 Biovalve Technologies, Inc. Microneedle array systems
JP4704583B2 (ja) * 2001-02-28 2011-06-15 有限会社開発顧問室 パッチテスト用シート
US6790179B2 (en) 2001-08-01 2004-09-14 Johnson & Johnson Consumer Companies, Inc. Method of examining and diagnosing skin health
US6840910B2 (en) 2001-08-01 2005-01-11 Johnson & Johnson Consumer Companies, Inc. Method of distributing skin care products
US6855117B2 (en) 2001-08-01 2005-02-15 Johnson & Johnson Consumer Companies, Inc. Method of treating the skin of a subject
AU2002327675A1 (en) 2001-09-19 2003-04-01 Biovalve Technologies, Inc. Microneedles, microneedle arrays, and systems and methods relating to same
EP1471953B1 (fr) 2001-09-21 2011-02-16 Valeritas, Inc. Amenagements de micro-aiguilles activees par pression de gaz, systemes et procedes correspondants
EP2319577B1 (fr) 2001-11-07 2017-03-15 Syneron Medical Ltd. Système intégré d'administration transdermale de médicaments
US7392080B2 (en) 2002-03-11 2008-06-24 Altea Therapeutics Corporation Transdermal drug delivery patch system, method of making same and method of using same
US9918665B2 (en) 2002-03-11 2018-03-20 Nitto Denko Corporation Transdermal porator and patch system and method for using same
AU2003226605A1 (en) 2002-04-19 2003-11-03 Transpharma Medical Ltd. Handheld transdermal drug delivery and analyte extraction
US8133505B2 (en) 2002-10-31 2012-03-13 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized medications
IL152573A (en) 2002-10-31 2009-11-18 Transpharma Medical Ltd A system for the transmission through the skin of a medical preparation against vomiting and nausea
US7383084B2 (en) 2002-10-31 2008-06-03 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized medications
IL152575A (en) 2002-10-31 2008-12-29 Transpharma Medical Ltd A skin-to-skin transmission system of water-insoluble drugs
US7662404B2 (en) 2002-10-31 2010-02-16 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized peptides and polypeptides
IL152574A (en) 2002-10-31 2009-09-22 Transpharma Medical Ltd A system for passing through the skin of dry items or dried medicines
US7258673B2 (en) 2003-06-06 2007-08-21 Lifescan, Inc Devices, systems and methods for extracting bodily fluid and monitoring an analyte therein
JP2007510445A (ja) * 2003-10-24 2007-04-26 アルザ・コーポレーシヨン 経皮薬剤送達促進用の前処置法及びシステム
US8016811B2 (en) 2003-10-24 2011-09-13 Altea Therapeutics Corporation Method for transdermal delivery of permeant substances
JP2007508914A (ja) * 2003-10-24 2007-04-12 アルザ・コーポレーシヨン 経皮薬剤送達を促進するための装置及び方法
JP2008517658A (ja) 2004-10-21 2008-05-29 バイエル・ヘルスケア・エルエルシー 体液内の分析物濃度を測定するための方法及び装置
JP2006326147A (ja) * 2005-05-30 2006-12-07 Shingo Wakamatsu レーザー治療装置
TWI419717B (zh) * 2005-06-17 2013-12-21 Altea Therapeutics Corp 滲透傳送系統及其使用方法
JP5011936B2 (ja) * 2006-10-11 2012-08-29 パナソニック株式会社 血液検査装置
JP5011935B2 (ja) * 2006-10-11 2012-08-29 パナソニック株式会社 血液検査装置
JP4706069B2 (ja) * 2006-11-14 2011-06-22 国立大学法人 鹿児島大学 薬物注入装置
NZ580997A (en) * 2007-04-27 2011-08-26 Echo Therapeutics Inc Dermal abrasion device with feedback electrode to deliver data on skin thickness and removable abrasion heads
WO2016141136A1 (fr) * 2015-03-03 2016-09-09 Guided Therapy Systems, Llc Procédés et systèmes pour l'administration assistée par ultrasons d'un médicament dans un tissu
CA2704740C (fr) 2007-10-09 2016-05-17 Transpharma Ltd. Fixation magnetique d'un timbre transdermique
CA2696227A1 (fr) 2007-10-17 2009-04-23 Transpharma Medical Ltd. Verification de la vitesse de dissolution
JP5407868B2 (ja) * 2007-11-06 2014-02-05 コニカミノルタ株式会社 微小開口形成装置およびそれを用いる体液収集システム
KR101304099B1 (ko) 2007-12-05 2013-09-05 시네론 메디컬 리미티드 일회용 전자기 에너지 애플리케이터 및 그 사용방법
GB0811856D0 (en) 2008-06-27 2008-07-30 Ucl Business Plc Magnetic microbubbles, methods of preparing them and their uses
US8606366B2 (en) 2009-02-18 2013-12-10 Syneron Medical Ltd. Skin treatment apparatus for personal use and method for using same
US20100256466A1 (en) * 2009-04-02 2010-10-07 Avraham Shekalim Metabolite Management System
EP2459092B1 (fr) * 2009-07-27 2019-09-18 Novoxel Ltd. Dispositif d'ablation de tissu
PT105635B (pt) 2011-04-19 2014-04-11 Univ De Coimbra Dispositivo para a administração eficiente de compostos na pele ou barreiras biológicas, ou através dessas, usando filmes finos absorventes de luz
JP2017503564A (ja) 2013-12-18 2017-02-02 ノヴォクセル リミテッド 組織気化装置および方法
US11083515B2 (en) 2013-12-18 2021-08-10 Novoxel Ltd. Methods and devices for thermal tissue vaporization and compression
JP2017536142A (ja) * 2014-09-15 2017-12-07 ノヴォクセル リミテッド 組織の熱外科的蒸散および切開のための方法および装置
CN108366751A (zh) * 2015-12-15 2018-08-03 皇家飞利浦有限公司 表面处理装置和方法
US20190029654A1 (en) * 2016-01-15 2019-01-31 University Of Cincinnati Advanced electroporation devices and methods for analyte access in biofluids
WO2017223003A1 (fr) * 2016-06-20 2017-12-28 University Of North Texas Usinage assisté par laser (lam) d'un matériau osseux composite non monolithique
FI127811B (en) * 2016-11-21 2019-03-15 Helsingin Yliopisto APPARATUS FOR SAMPLING ONE OR MORE ANALYTICAL SAMPLES
EP3361402A1 (fr) * 2017-02-14 2018-08-15 Roche Diabetes Care GmbH Méthode, produit de programme informatique et dispositif portable pour l'analyse des niveaux de glucose dans un liquide de corps au moyen de données de surveillance de glucose
US11441994B2 (en) * 2017-07-27 2022-09-13 Tata Consultancy Services Limited Method and system for in-silico design of skin electroporation
CA3071766A1 (fr) * 2017-08-03 2019-02-07 Fibrotx Ou Dosage d'ecoulement lateral et dispositif pour application de soins de la peau
CN109157280A (zh) * 2018-08-10 2019-01-08 重庆大学 不可逆电穿孔组织消融效果动态实时评估设备
JP2022540052A (ja) * 2019-06-28 2022-09-14 パスポート テクノロジーズ、インコーポレイテッド フィラメント装置への熱送達を制御するための方法およびシステム
CN112294298A (zh) * 2019-08-02 2021-02-02 华广生技股份有限公司 生物传感器的植入装置及其植入方法
CN110613893A (zh) * 2019-10-31 2019-12-27 南京工业职业技术学院 一种新型励磁线圈
CN111693434B (zh) * 2020-06-19 2024-01-19 中建路桥集团有限公司 一种测试混凝土抗渗性能的实验装置
CN114504373A (zh) * 2020-11-16 2022-05-17 澳美力科技(成都)有限公司 一种新型射频变频美容仪
CN112957124B (zh) * 2021-01-30 2023-08-22 南京理工大学 一种能量靶向调控的离体激光生物组织焊接缝合方法
CN115670642A (zh) * 2021-05-20 2023-02-03 黄虹凤 保证高精度和高速度的激光切线装置
CN114343839A (zh) * 2021-12-30 2022-04-15 德州环球之光医疗科技有限公司 一种基于可调的螺旋线型激光光斑的治疗图形转换方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4775361A (en) * 1986-04-10 1988-10-04 The General Hospital Corporation Controlled removal of human stratum corneum by pulsed laser to enhance percutaneous transport
US4863970A (en) * 1986-11-14 1989-09-05 Theratech, Inc. Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols
DE68925030T2 (de) * 1988-01-21 1996-07-25 Massachusetts Inst Technology Molekültransport durch gewebe mit der verwendung von elektroporation.
US5139023A (en) 1989-06-02 1992-08-18 Theratech Inc. Apparatus and method for noninvasive blood glucose monitoring
US5016615A (en) * 1990-02-20 1991-05-21 Riverside Research Institute Local application of medication with ultrasound
US5115805A (en) * 1990-02-23 1992-05-26 Cygnus Therapeutic Systems Ultrasound-enhanced delivery of materials into and through the skin
GB9014307D0 (en) 1990-06-27 1990-08-15 Scient Generics Ltd Method of treatment and compositions therefor
JP3189337B2 (ja) * 1991-11-08 2001-07-16 日本電気株式会社 皮膚角層の除去器具および除去方法
US5344418A (en) * 1991-12-12 1994-09-06 Shahriar Ghaffari Optical system for treatment of vascular lesions
US5165418B1 (en) 1992-03-02 1999-12-14 Nikola I Tankovich Blood sampling device and method using a laser
US5246437A (en) * 1992-04-10 1993-09-21 Abela George S Cell treatment apparatus and method
US5643252A (en) * 1992-10-28 1997-07-01 Venisect, Inc. Laser perforator
US5279552A (en) * 1993-01-11 1994-01-18 Anton Magnet Intradermal injection device
US5267985A (en) * 1993-02-11 1993-12-07 Trancell, Inc. Drug delivery by multiple frequency phonophoresis
US5582184A (en) * 1993-10-13 1996-12-10 Integ Incorporated Interstitial fluid collection and constituent measurement
US5445611A (en) * 1993-12-08 1995-08-29 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal delivery with ultrasound and chemical enhancers
US5458140A (en) 1993-11-15 1995-10-17 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers
EP0781150B1 (fr) * 1995-07-25 2002-11-06 Massachusetts Institute Of Technology Transport transdermique ameliore grace aux ultrasons

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HK1009321A1 (en) 1999-05-28
CN1174713C (zh) 2004-11-10
IL123379A (en) 2002-04-21
ES2536459T3 (es) 2015-05-25
BR9610012A (pt) 1999-12-21
AU6863196A (en) 1997-03-19
JPH11511360A (ja) 1999-10-05
GB2307414B (en) 1998-03-11
JP3899427B2 (ja) 2007-03-28
CA2199002A1 (fr) 1997-03-01
JP2006192285A (ja) 2006-07-27
AU707065B2 (en) 1999-07-01
NO980878L (no) 1998-04-27
EP0858285A4 (fr) 2000-05-17
CA2199002C (fr) 1999-02-23
GB2307414A (en) 1997-05-28
NO334437B1 (no) 2014-03-03
WO1997007734A1 (fr) 1997-03-06
PT1563788E (pt) 2015-06-02
EP0858285A1 (fr) 1998-08-19
GB9702766D0 (en) 1997-04-02
NO980878D0 (no) 1998-02-27
IL123379A0 (en) 1998-09-24
CN1195276A (zh) 1998-10-07

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