TR199600421A2 - Florfenil ikameli alkenil karbon asit-guanidid, bunlarin imalatina mahsus usul, bunlarin ilac ya da diagnoz maddesi olarak kullanilmalari ve bunlari ihtiva eden ilaclar. - Google Patents

Florfenil ikameli alkenil karbon asit-guanidid, bunlarin imalatina mahsus usul, bunlarin ilac ya da diagnoz maddesi olarak kullanilmalari ve bunlari ihtiva eden ilaclar.

Info

Publication number
TR199600421A2
TR199600421A2 TR96/00421A TR9600421A TR199600421A2 TR 199600421 A2 TR199600421 A2 TR 199600421A2 TR 96/00421 A TR96/00421 A TR 96/00421A TR 9600421 A TR9600421 A TR 9600421A TR 199600421 A2 TR199600421 A2 TR 199600421A2
Authority
TR
Turkey
Prior art keywords
florphenyl
guanidide
drug
manufacture
substituted alkenyl
Prior art date
Application number
TR96/00421A
Other languages
English (en)
Inventor
Dr Jan-Robert Schwark
Dr Hans-Jochen Lang
Dr Heinz-Werner Kleemann
Dr Andreas Weichert
Dr Wolfgang Scholz
Dr Udo Albus
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of TR199600421A2 publication Critical patent/TR199600421A2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/10—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by doubly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Surgery (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TR96/00421A 1995-05-22 1996-05-20 Florfenil ikameli alkenil karbon asit-guanidid, bunlarin imalatina mahsus usul, bunlarin ilac ya da diagnoz maddesi olarak kullanilmalari ve bunlari ihtiva eden ilaclar. TR199600421A2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19518796A DE19518796A1 (de) 1995-05-22 1995-05-22 Fluorphenylsubstituierte Alkenylcarbonsäure-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (1)

Publication Number Publication Date
TR199600421A2 true TR199600421A2 (tr) 1997-03-21

Family

ID=7762597

Family Applications (1)

Application Number Title Priority Date Filing Date
TR96/00421A TR199600421A2 (tr) 1995-05-22 1996-05-20 Florfenil ikameli alkenil karbon asit-guanidid, bunlarin imalatina mahsus usul, bunlarin ilac ya da diagnoz maddesi olarak kullanilmalari ve bunlari ihtiva eden ilaclar.

Country Status (29)

Country Link
US (2) US20010020042A1 (tr)
EP (1) EP0744397B1 (tr)
JP (1) JP3924018B2 (tr)
KR (1) KR960041152A (tr)
CN (1) CN1063437C (tr)
AR (1) AR002744A1 (tr)
AT (1) ATE192431T1 (tr)
AU (1) AU701493B2 (tr)
BR (1) BR9602394A (tr)
CA (1) CA2177007C (tr)
CZ (1) CZ291622B6 (tr)
DE (2) DE19518796A1 (tr)
DK (1) DK0744397T3 (tr)
ES (1) ES2147629T3 (tr)
GR (1) GR3033416T3 (tr)
HR (1) HRP960230B1 (tr)
HU (1) HUP9601358A3 (tr)
IL (1) IL118327A (tr)
MY (1) MY113803A (tr)
NO (1) NO305552B1 (tr)
NZ (1) NZ286622A (tr)
PL (1) PL183431B1 (tr)
PT (1) PT744397E (tr)
RU (1) RU2164913C2 (tr)
SI (1) SI0744397T1 (tr)
SK (1) SK281527B6 (tr)
TR (1) TR199600421A2 (tr)
TW (1) TW415936B (tr)
ZA (1) ZA964035B (tr)

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CA2370607A1 (en) 1999-04-23 2000-11-02 Bristol-Myers Squibb Company Bicyclic acyl guanidine sodium/proton exchange inhibitors and method
DE10046993A1 (de) 2000-09-22 2002-04-11 Aventis Pharma Gmbh Substituierte Zimtsäureguanidide, Verfahren zur ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltendes Medikament
EP2617709B8 (en) * 2003-06-26 2022-12-21 Biotron Limited Guanidine derivatives as antiviral agents
BRPI0612309B8 (pt) 2005-06-24 2021-05-25 Biotron Ltd compostos e composições farmacêuticas antivirais
AU2013205388B2 (en) * 2005-06-24 2016-05-05 Biotron Limited Antiviral compounds and methods
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WO2018129556A1 (en) 2017-01-09 2018-07-12 Ardelyx, Inc. Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
MX366293B (es) 2012-08-21 2019-07-04 Ardelyx Inc Compuestos y metodos para inhibir al antipuerto mediado por nhe en el tratamiento de trastornos asociados con la retencion de fluidos o la sobrecarga de sal y trastornos del tracto gastrointestinal.
US10376481B2 (en) 2012-08-21 2019-08-13 Ardelyx, Inc. Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
JP6377132B2 (ja) 2013-04-12 2018-08-22 アーデリクス，インコーポレーテッド Ｎｈｅ３結合化合物およびリン酸輸送の阻害方法
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Also Published As

Publication number Publication date
ES2147629T3 (es) 2000-09-16
HUP9601358A3 (en) 1997-10-28
DE59605101D1 (de) 2000-06-08
US20020123529A1 (en) 2002-09-05
NZ286622A (en) 1997-08-22
MY113803A (en) 2002-05-31
NO962063D0 (no) 1996-05-21
JP3924018B2 (ja) 2007-06-06
EP0744397B1 (de) 2000-05-03
US6504057B2 (en) 2003-01-07
IL118327A0 (en) 1996-09-12
SK281527B6 (sk) 2001-04-09
US20010020042A1 (en) 2001-09-06
IL118327A (en) 2002-12-01
EP0744397A3 (de) 1997-03-26
JPH08319266A (ja) 1996-12-03
CA2177007A1 (en) 1996-11-23
RU2164913C2 (ru) 2001-04-10
AU701493B2 (en) 1999-01-28
SI0744397T1 (en) 2000-08-31
AR002744A1 (es) 1998-04-29
HUP9601358A2 (en) 1997-05-28
PT744397E (pt) 2000-09-29
ZA964035B (en) 1997-11-21
CZ145096A3 (en) 1996-12-11
GR3033416T3 (en) 2000-09-29
KR960041152A (ko) 1996-12-19
BR9602394A (pt) 1998-10-06
NO305552B1 (no) 1999-06-21
CN1138029A (zh) 1996-12-18
HRP960230A2 (en) 1997-12-31
ATE192431T1 (de) 2000-05-15
DE19518796A1 (de) 1996-11-28
PL314252A1 (en) 1996-11-25
CZ291622B6 (cs) 2003-04-16
AU5237396A (en) 1996-12-05
NO962063L (no) 1996-11-25
DK0744397T3 (da) 2000-08-28
HRP960230B1 (en) 2000-12-31
TW415936B (en) 2000-12-21
HU9601358D0 (en) 1996-07-29
SK65196A3 (en) 1996-12-04
PL183431B1 (pl) 2002-06-28
CA2177007C (en) 2009-01-06
EP0744397A2 (de) 1996-11-27
CN1063437C (zh) 2001-03-21

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