TR199500952A2 - Anti-astimatik, anti-alerjik, anti-enflamatuar ve imünmodüle edici etkiye sahip yeni n-benzilindol ve benzopirazol türevleri. - Google Patents

Anti-astimatik, anti-alerjik, anti-enflamatuar ve imünmodüle edici etkiye sahip yeni n-benzilindol ve benzopirazol türevleri.

Info

Publication number
TR199500952A2
TR199500952A2 TR95/00952A TR9500952A TR199500952A2 TR 199500952 A2 TR199500952 A2 TR 199500952A2 TR 95/00952 A TR95/00952 A TR 95/00952A TR 9500952 A TR9500952 A TR 9500952A TR 199500952 A2 TR199500952 A2 TR 199500952A2
Authority
TR
Turkey
Prior art keywords
benzylindole
asthmatic
allergic
inflammatory
new
Prior art date
Application number
TR95/00952A
Other languages
English (en)
Inventor
Prof Guillaume Lebaut
Fabienne Fouchard
Dr Bernhard Kutscher
Dr Peter Emig
Dr Ilona Fleischhaur
Prof Dr Stefan Szelenyi
Dr Jurgen Schmidt
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19511916A external-priority patent/DE19511916A1/de
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of TR199500952A2 publication Critical patent/TR199500952A2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
TR95/00952A 1994-08-03 1995-08-03 Anti-astimatik, anti-alerjik, anti-enflamatuar ve imünmodüle edici etkiye sahip yeni n-benzilindol ve benzopirazol türevleri. TR199500952A2 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4427393 1994-08-03
DE19511916A DE19511916A1 (de) 1994-08-03 1995-03-31 Neue N-Benzylindol- und Benzopyrazol-Derivate mit antiasthmatischer, antiallergischer, entzündungshemmender und immunmodulierender Wirkung

Publications (1)

Publication Number Publication Date
TR199500952A2 true TR199500952A2 (tr) 1996-07-21

Family

ID=25938901

Family Applications (1)

Application Number Title Priority Date Filing Date
TR95/00952A TR199500952A2 (tr) 1994-08-03 1995-08-03 Anti-astimatik, anti-alerjik, anti-enflamatuar ve imünmodüle edici etkiye sahip yeni n-benzilindol ve benzopirazol türevleri.

Country Status (13)

Country Link
US (1) US5965582A (tr)
EP (1) EP0775131A2 (tr)
JP (1) JPH10503501A (tr)
AU (1) AU3162695A (tr)
CA (1) CA2195850A1 (tr)
EG (1) EG21559A (tr)
FI (1) FI971334A (tr)
HR (1) HRP950435A2 (tr)
IL (1) IL114795A (tr)
NO (1) NO970412L (tr)
TR (1) TR199500952A2 (tr)
TW (1) TW434227B (tr)
WO (1) WO1996004266A2 (tr)

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US6673827B1 (en) 1999-06-29 2004-01-06 The Uab Research Foundation Methods of treating fungal infections with inhibitors of NAD synthetase enzyme
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DE19821002A1 (de) * 1998-05-11 1999-11-18 Dresden Arzneimittel Neue 1,5- und 3-O-substituierte 1H-Indazole mit antiasthmatischer, antiallergischer, entzündungshemmender, immunmodulierender und neuroprotektiver Wirkung, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US6362213B1 (en) 1999-12-23 2002-03-26 Icos Corporation Cyclic AMP-specific phosphodiesterase inhibitors
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DE10037310A1 (de) * 2000-07-28 2002-02-07 Asta Medica Ag Neue Indolderivate und deren Verwendung als Arzneimittel
JP2005504790A (ja) * 2001-09-13 2005-02-17 シンタ ファーマスーティカルズ コーポレイション 癌を治療するための３−グリオキシリルアミドインドール
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US20040048866A1 (en) * 2002-03-08 2004-03-11 Teodozyj Kolasa Indazole derivatives that are activators of soluble guanylate cyclase
US20050089559A1 (en) * 2003-10-23 2005-04-28 Istvan Szelenyi Combinations of potassium channel openers and sodium channel inhibitors or sodium channel-influencing active compounds for treating pains
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CA2660704A1 (en) * 2006-08-07 2008-02-14 Ironwood Pharmaceuticals, Inc. Indole compounds
US8722929B2 (en) * 2006-10-10 2014-05-13 Valeant Pharmaceuticals International N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators
US8367684B2 (en) * 2007-06-13 2013-02-05 Valeant Pharmaceuticals International Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators
US8563566B2 (en) * 2007-08-01 2013-10-22 Valeant Pharmaceuticals International Naphthyridine derivatives as potassium channel modulators
US7786146B2 (en) * 2007-08-13 2010-08-31 Valeant Pharmaceuticals International Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators
KR101470933B1 (ko) * 2007-09-14 2014-12-09 얀센 파마슈티카 엔.브이. 히스타민 ｈ4 수용체의 티에노- 및 푸로-피리미딘 조절제
AR084433A1 (es) 2010-12-22 2013-05-15 Ironwood Pharmaceuticals Inc Inhibidores de la faah y composiciones farmaceuticas que los contienen
WO2013019690A1 (en) * 2011-07-29 2013-02-07 The Ohio State University Small molecule inhibitors of il-6 and uses thereof
US9862698B2 (en) 2014-12-16 2018-01-09 Adt Pharmaceuticals, Inc. Indenyl compounds, pharmaceutical compositions, and medical uses thereof
US20160168108A1 (en) 2014-12-16 2016-06-16 Adt Pharmaceuticals, Inc. Method of treating or preventing ras-mediated diseases
WO2019210223A1 (en) * 2018-04-26 2019-10-31 Adt Pharmaceuticals, Llc Anticancer indenes, indanes, azaindenes, azaindanes, pharmaceutical compositions and uses
WO2022211518A1 (ko) * 2021-04-02 2022-10-06 파렌키마바이오텍 주식회사 신규 화합물 및 이의 건선, 천식 또는 전신홍반루푸스의 치료 용도

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Also Published As

Publication number Publication date
FI971334A0 (fi) 1997-04-01
HRP950435A2 (en) 1997-12-31
FI971334A (fi) 1997-04-01
WO1996004266A3 (de) 1996-05-17
TW434227B (en) 2001-05-16
CA2195850A1 (en) 1996-02-15
NO970412D0 (no) 1997-01-30
EG21559A (en) 2001-12-31
US5965582A (en) 1999-10-12
NO970412L (no) 1997-02-27
IL114795A (en) 1999-11-30
IL114795A0 (en) 1995-12-08
EP0775131A2 (de) 1997-05-28
WO1996004266A2 (de) 1996-02-15
JPH10503501A (ja) 1998-03-31
AU3162695A (en) 1996-03-04

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