TNSN97125A1 - Composes furanne-nitrone - Google Patents

Composes furanne-nitrone

Info

Publication number
TNSN97125A1
TNSN97125A1 TNTNSN97125A TNSN97125A TNSN97125A1 TN SN97125 A1 TNSN97125 A1 TN SN97125A1 TN TNSN97125 A TNTNSN97125 A TN TNSN97125A TN SN97125 A TNSN97125 A TN SN97125A TN SN97125 A1 TNSN97125 A1 TN SN97125A1
Authority
TN
Tunisia
Prior art keywords
furanne
compounds
nitrone compounds
disclosed
nitrone
Prior art date
Application number
TNTNSN97125A
Other languages
English (en)
Inventor
Judith A Kelleher
Kirk R Maples
Lowel David Waterbury
Allan L Wilcox
Hong Xu
Yong-Kang Zhang
Original Assignee
Centaur Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centaur Pharmaceuticals Inc filed Critical Centaur Pharmaceuticals Inc
Publication of TNSN97125A1 publication Critical patent/TNSN97125A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/64—Sulfur atoms

Abstract

SONT DIVULGUES DES COMPOSES FURANNE-NITRONE ET DES COMPOSITIONS PHARMACEUTIQUE CONTENANT DE TELS COMPOSES. LES COMPOSES DIVULGUES SONT UTILES COMME REACTIFS ANALYTIQUES POUR LA DETECTION DE RADICAUX LIBRES ET COMME MOYEN THERAPEUTIQUE POUR LE TRAITEMENT D'UN LARGE EVENTAIL DE DYSONCTIONS MEDICALES ET DE MALADIES
TNTNSN97125A 1996-07-19 1997-07-18 Composes furanne-nitrone TNSN97125A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2216996P 1996-07-19 1996-07-19

Publications (1)

Publication Number Publication Date
TNSN97125A1 true TNSN97125A1 (fr) 2005-03-15

Family

ID=21808169

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN97125A TNSN97125A1 (fr) 1996-07-19 1997-07-18 Composes furanne-nitrone

Country Status (16)

Country Link
US (4) US6376540B1 (fr)
EP (1) EP1021430A1 (fr)
JP (1) JP2000514822A (fr)
KR (1) KR20000067915A (fr)
AR (1) AR008781A1 (fr)
AU (1) AU715226B2 (fr)
CA (1) CA2260825A1 (fr)
CO (1) CO4910142A1 (fr)
HR (1) HRP970381A2 (fr)
ID (1) ID19679A (fr)
IL (1) IL128070A0 (fr)
MA (1) MA26434A1 (fr)
NZ (1) NZ333705A (fr)
TN (1) TNSN97125A1 (fr)
WO (1) WO1998003496A1 (fr)
ZA (1) ZA976388B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW429241B (en) * 1996-09-26 2001-04-11 Sumitomo Pharma Nitrone derivatives
US5998469A (en) * 1998-01-16 1999-12-07 Centaur Pharmaceuticals, Inc. Thioether furan nitrone compounds
CN1136212C (zh) * 1998-01-16 2004-01-28 桑道药品有限公司 噻吩硝酮化合物
WO1999059579A1 (fr) * 1998-05-19 1999-11-25 Centaur Pharmaceuticals, Inc. Medicament a base de nitrone furanique, destine au traitement des affections inflammatoires de l'intestin
AU750599B2 (en) 1998-07-17 2002-07-25 Renovis, Inc. Alpha-(2-hydroxyphenyl) nitrone compounds, pharmaceutical compositions containing the same and their use for treating inflammation
US6730700B2 (en) * 1998-12-02 2004-05-04 Renovis, Inc. 3,4,5,-trisubstituted aryl nitrone compounds and pharmaceutical compositions containing the same
UA66401C2 (en) 1998-12-02 2004-05-17 Sentor Pharmaceuticals Inc 3,4,5-trisubstituted aryl nitrone compounds and pharmaceutical composition containing the same
EP1562975A2 (fr) * 2002-10-25 2005-08-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Composes steroides comprenant des groupes mimetiques de la superoxyde dismutase et des groupes donneurs d'oxyde nitrique, et leur utilisation dans la preparation de medicaments
US20060166894A1 (en) * 2002-11-29 2006-07-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ace-inhibitors having antioxidant and no-donor activity
US20050059638A1 (en) * 2003-08-04 2005-03-17 Kelly Michael G. Aryl, heteroaromatic and bicyclic aryl nitrone compounds, prodrugs and pharmaceutical compositions of the same to treat human disorders
US20050182060A1 (en) * 2004-02-13 2005-08-18 Kelly Michael G. 2-Substituted and 4-substituted aryl nitrone compounds
US9034926B2 (en) 2010-12-30 2015-05-19 Nicholas V. Perricone Topical nitrone spin trap compositions for psoriasis
US8986739B2 (en) 2011-02-28 2015-03-24 Nicholas V. Perricone Treatment of urinary incontinence using nitrone spin traps

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3666754A (en) 1965-11-06 1972-05-30 Dainippon Pharmaceutical Co 2-(5-nitrofuryl) nitrone derivatives
US3988159A (en) 1967-07-28 1976-10-26 American Can Company Light-sensitive material containing nitrone for forming heat-fixed images
US3849934A (en) 1971-05-03 1974-11-26 Scm Corp Alpha-aryl-n-lower alkyl nitrone-containing compositions useful as anti-fungal agents
US3834073A (en) 1971-05-03 1974-09-10 Scm Corp Phenyl nitrone derivatives useful as seed protectants
US3950327A (en) 1972-09-19 1976-04-13 Ciba-Geigy Corporation New nitrones, their manufacture and their use for the manufacture of n-substituted araliphatic aldehyde-nitrones
US3917700A (en) 1974-01-30 1975-11-04 Goodyear Tire & Rubber Nitrone compounds
US3903049A (en) 1974-01-30 1975-09-02 Goodyear Tire & Rubber Oxidation resistant sulfur curable rubbery polymers
GB1588417A (en) 1977-03-15 1981-04-23 Agfa Gevaert Photoresist materials
US4153722A (en) 1977-10-06 1979-05-08 William H. Rorer, Inc. Method of treatment
GB2137619A (en) 1983-03-30 1984-10-10 Gerald Scott Nitrone compounds and stabilised rubber compositions containing them
US5352442A (en) 1985-07-18 1994-10-04 Proctor Peter H Topical tempo
US5723502A (en) 1985-07-18 1998-03-03 Proctor; Peter H. Topical spin trap composition and method
US4871862A (en) 1986-08-27 1989-10-03 Fisons Corporation α-Substituted ketonitrone derivatives
US4803282A (en) 1986-08-27 1989-02-07 Pennwalt Corporation Alpha-substituted ketonitrone derivatives
EP0327263B1 (fr) 1988-01-29 1994-09-07 PROCTOR, Peter H. Stimulation de la croissance des cheveux avec nitroxide et autres radicaux
JP2620413B2 (ja) * 1989-10-17 1997-06-11 オクラホマ メディカル リサーチ ファウンデーション 酸化的損傷に伴う疾患の阻止方法および組成物
ATE209908T1 (de) * 1991-06-18 2001-12-15 Oklahoma Med Res Found RADIKALFÄNGER (ßSPIN TRAPSß) ZUR BEHANDLUNG VON MIT OXIDATION VON LIPIDEN UND PROTEINEN VERBUNDENEN ERKRANKUNGEN
US5292746A (en) 1991-09-12 1994-03-08 Merrell Dow Pharmaceuticals Inc. Cyclic nitrones, pharmaceutical compositions thereof and their use in treating shock
GB9300894D0 (en) 1992-02-07 1993-03-10 Zeneca Ltd Oxime derivatives
US5455272A (en) 1993-10-22 1995-10-03 Oklahoma Medical Research Foundation Spin trap nitronyl hindered phenols
US5488145A (en) 1993-12-23 1996-01-30 Oklahoma Medical Research Foundation 2,4-disulfonyl phenyl butyl nitrone, its salts, and their use as pharmaceutical free radical traps
WO1997019054A1 (fr) 1995-11-17 1997-05-29 Florida International University Agents de piegeage de spin a base d'azulenyl-nitrones, et leurs procedes de fabrication et d'utilisation
TW429241B (en) 1996-09-26 2001-04-11 Sumitomo Pharma Nitrone derivatives

Also Published As

Publication number Publication date
ID19679A (id) 1998-07-30
ZA976388B (en) 1998-02-19
HRP970381A2 (en) 1998-08-31
US6051571A (en) 2000-04-18
MA26434A1 (fr) 2004-12-20
US5942507A (en) 1999-08-24
AR008781A1 (es) 2000-02-23
NZ333705A (en) 2000-09-29
CO4910142A1 (es) 2000-04-24
WO1998003496A1 (fr) 1998-01-29
JP2000514822A (ja) 2000-11-07
US6376540B1 (en) 2002-04-23
AU715226B2 (en) 2000-01-20
US6040444A (en) 2000-03-21
EP1021430A1 (fr) 2000-07-26
CA2260825A1 (fr) 1998-01-29
AU3655597A (en) 1998-02-10
KR20000067915A (ko) 2000-11-25
IL128070A0 (en) 1999-11-30

Similar Documents

Publication Publication Date Title
TNSN97125A1 (fr) Composes furanne-nitrone
HUP9902105A2 (hu) Angiosztatikus dipeptideket tartalmazó gyógyászati készítmények és ezek alkalmazása
DZ2045A1 (fr) Amides thérapeutiques, procédé pour leur préparation et compositions les contenant.
TNSN94105A1 (fr) Composes sulfonamides tricycliques utiles pour l'inhibition de la fonction proteine g et pour le traitement des maladies proliferatives
MA28289A1 (fr) Immunoglobulines
DZ2186A1 (fr) Compositions pharmaceutiques mixtes pour le traitement de l'ostéoporose et procédé pour leur préparation.
MA26586A1 (fr) Association pharmaceutique pour le traitement d'un dysfonctionnement sexuel et compositions la contenant
TNSN96075A1 (fr) N-(indole-2-carbonyl) - beta- alaninamides substitues et leurs derives, servant d'agents antidiabetiques
FR10C0016I2 (fr) Procedes et compositions s'appliquant au traitement de la glomerulonephrite
DE69625691D1 (de) Verabreichung von peptidylheterocyclen zur behandlung von thrombin in zusammenhang stehenden krankheiten
TNSN97192A1 (fr) Derives de pyrimidine bicycliques condenses, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2393573A1 (fr) Preparations capillaires contenant un copolymere de vinylpyrrolidone
DZ2538A1 (fr) Tartrate d'un dipeptide substitué procédé pour sa préparation et compositions pharmaceutiques le contenant.
FR2745016B1 (fr) Composition pour une lotion adoucissante, utilisation de la lotion pour le traitement d'un produit papetier absorbant et produit papetier absorbant ainsi traite
MX9704030A (es) 1,1-dioxidos de 2-heterocicliloxi y tiometil-1,2,5-tiadiazolidin-3-ona y composiciones y metodo de uso de los mismos.
FR2787789B1 (fr) Benzopyranes et benzoxepines utilisables dans le traitement de dyslipidemies, de l'atherosclerose et du diabete, compositions pharmaceutiques les contenant et procedes de preparations
TNSN98024A1 (fr) 2-amino-6-(2-substitue-4-phenoxy)-substitue-pyridines, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2623508B1 (fr) Proteine basique denommee phospholipase a2 isolee de venin de serpent de la famille des elapides et sa sequence en amino-acides, derives et fragments de ladite proteine, leur procede d'obtention, compositions therapeutiques et agents de diagnostic contenant ladite proteine et/ou ses derives et/ou ses fragments
FR2742657B1 (fr) Compositions pour le traitement des matieres keratiniques contenant l'association d'un polymere polyampholyte et d'un polymere cationique
FR2649324B1 (fr) Article souple pour traitement chirurgical, ensemble le comprenant et son procede d'utilisation
MA26658A1 (fr) Derivés de valérohydrazine, procédé pour les préparer, médicament pour le traitement des maladies inflammatoires et auto-immunes les contenant, et leur utilisation pour préparer un tel médicament
TNSN98185A1 (fr) Derives d'isoquinoleine nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2739292B1 (fr) Composition pharmaceutique utile pour la transfection d'acides nucleiques et ses utilisations
BE900012A (fr) Nouveau peptide.
FR2746314B1 (fr) Produit contenant du milnacipran et de l'idazoxan comme preparation pharmaceutique combinee