AR008781A1 - Compuestos de furano nitrona - Google Patents
Compuestos de furano nitronaInfo
- Publication number
- AR008781A1 AR008781A1 ARP970103231A ARP970103231A AR008781A1 AR 008781 A1 AR008781 A1 AR 008781A1 AR P970103231 A ARP970103231 A AR P970103231A AR P970103231 A ARP970103231 A AR P970103231A AR 008781 A1 AR008781 A1 AR 008781A1
- Authority
- AR
- Argentina
- Prior art keywords
- compounds
- nitrona
- furano
- discovered
- therapeutics
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/64—Sulfur atoms
Abstract
Se descubren compuestos de furano nitrona y composiciones farmacéuticas que contienen dichos compuestos. Los compuestos descubiertos son utiles comoreactivos analíticos para la deteccion de radicales libres y como terapéuticos para el trata miento de una amplia variedad de enfermedades y disfuncionesmédicas.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2216996P | 1996-07-19 | 1996-07-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR008781A1 true AR008781A1 (es) | 2000-02-23 |
Family
ID=21808169
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP970103231A AR008781A1 (es) | 1996-07-19 | 1997-07-18 | Compuestos de furano nitrona |
Country Status (16)
Country | Link |
---|---|
US (4) | US6376540B1 (es) |
EP (1) | EP1021430A1 (es) |
JP (1) | JP2000514822A (es) |
KR (1) | KR20000067915A (es) |
AR (1) | AR008781A1 (es) |
AU (1) | AU715226B2 (es) |
CA (1) | CA2260825A1 (es) |
CO (1) | CO4910142A1 (es) |
HR (1) | HRP970381A2 (es) |
ID (1) | ID19679A (es) |
IL (1) | IL128070A0 (es) |
MA (1) | MA26434A1 (es) |
NZ (1) | NZ333705A (es) |
TN (1) | TNSN97125A1 (es) |
WO (1) | WO1998003496A1 (es) |
ZA (1) | ZA976388B (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW429241B (en) * | 1996-09-26 | 2001-04-11 | Sumitomo Pharma | Nitrone derivatives |
US5998469A (en) * | 1998-01-16 | 1999-12-07 | Centaur Pharmaceuticals, Inc. | Thioether furan nitrone compounds |
CN1136212C (zh) * | 1998-01-16 | 2004-01-28 | 桑道药品有限公司 | 噻吩硝酮化合物 |
WO1999059579A1 (en) * | 1998-05-19 | 1999-11-25 | Centaur Pharmaceuticals, Inc. | Furan nitrone therapeutics for the treatment of inflammatory bowel disease |
AU750599B2 (en) | 1998-07-17 | 2002-07-25 | Renovis, Inc. | Alpha-(2-hydroxyphenyl) nitrone compounds, pharmaceutical compositions containing the same and their use for treating inflammation |
US6730700B2 (en) * | 1998-12-02 | 2004-05-04 | Renovis, Inc. | 3,4,5,-trisubstituted aryl nitrone compounds and pharmaceutical compositions containing the same |
UA66401C2 (en) | 1998-12-02 | 2004-05-17 | Sentor Pharmaceuticals Inc | 3,4,5-trisubstituted aryl nitrone compounds and pharmaceutical composition containing the same |
EP1562975A2 (en) * | 2002-10-25 | 2005-08-17 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Steroid compounds comprising superoxide dismutase mimic groups and nitric oxide donor groups, and their use in the preparation of medicaments |
US20060166894A1 (en) * | 2002-11-29 | 2006-07-27 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Ace-inhibitors having antioxidant and no-donor activity |
US20050059638A1 (en) * | 2003-08-04 | 2005-03-17 | Kelly Michael G. | Aryl, heteroaromatic and bicyclic aryl nitrone compounds, prodrugs and pharmaceutical compositions of the same to treat human disorders |
US20050182060A1 (en) * | 2004-02-13 | 2005-08-18 | Kelly Michael G. | 2-Substituted and 4-substituted aryl nitrone compounds |
US9034926B2 (en) | 2010-12-30 | 2015-05-19 | Nicholas V. Perricone | Topical nitrone spin trap compositions for psoriasis |
US8986739B2 (en) | 2011-02-28 | 2015-03-24 | Nicholas V. Perricone | Treatment of urinary incontinence using nitrone spin traps |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3666754A (en) | 1965-11-06 | 1972-05-30 | Dainippon Pharmaceutical Co | 2-(5-nitrofuryl) nitrone derivatives |
US3988159A (en) | 1967-07-28 | 1976-10-26 | American Can Company | Light-sensitive material containing nitrone for forming heat-fixed images |
US3849934A (en) | 1971-05-03 | 1974-11-26 | Scm Corp | Alpha-aryl-n-lower alkyl nitrone-containing compositions useful as anti-fungal agents |
US3834073A (en) | 1971-05-03 | 1974-09-10 | Scm Corp | Phenyl nitrone derivatives useful as seed protectants |
US3950327A (en) | 1972-09-19 | 1976-04-13 | Ciba-Geigy Corporation | New nitrones, their manufacture and their use for the manufacture of n-substituted araliphatic aldehyde-nitrones |
US3917700A (en) | 1974-01-30 | 1975-11-04 | Goodyear Tire & Rubber | Nitrone compounds |
US3903049A (en) | 1974-01-30 | 1975-09-02 | Goodyear Tire & Rubber | Oxidation resistant sulfur curable rubbery polymers |
GB1588417A (en) | 1977-03-15 | 1981-04-23 | Agfa Gevaert | Photoresist materials |
US4153722A (en) | 1977-10-06 | 1979-05-08 | William H. Rorer, Inc. | Method of treatment |
GB2137619A (en) | 1983-03-30 | 1984-10-10 | Gerald Scott | Nitrone compounds and stabilised rubber compositions containing them |
US5352442A (en) | 1985-07-18 | 1994-10-04 | Proctor Peter H | Topical tempo |
US5723502A (en) | 1985-07-18 | 1998-03-03 | Proctor; Peter H. | Topical spin trap composition and method |
US4871862A (en) | 1986-08-27 | 1989-10-03 | Fisons Corporation | α-Substituted ketonitrone derivatives |
US4803282A (en) | 1986-08-27 | 1989-02-07 | Pennwalt Corporation | Alpha-substituted ketonitrone derivatives |
EP0327263B1 (en) | 1988-01-29 | 1994-09-07 | PROCTOR, Peter H. | Hair growth stimulation with nitroxide and other radicals |
JP2620413B2 (ja) * | 1989-10-17 | 1997-06-11 | オクラホマ メディカル リサーチ ファウンデーション | 酸化的損傷に伴う疾患の阻止方法および組成物 |
ATE209908T1 (de) * | 1991-06-18 | 2001-12-15 | Oklahoma Med Res Found | RADIKALFÄNGER (ßSPIN TRAPSß) ZUR BEHANDLUNG VON MIT OXIDATION VON LIPIDEN UND PROTEINEN VERBUNDENEN ERKRANKUNGEN |
US5292746A (en) | 1991-09-12 | 1994-03-08 | Merrell Dow Pharmaceuticals Inc. | Cyclic nitrones, pharmaceutical compositions thereof and their use in treating shock |
GB9300894D0 (en) | 1992-02-07 | 1993-03-10 | Zeneca Ltd | Oxime derivatives |
US5455272A (en) | 1993-10-22 | 1995-10-03 | Oklahoma Medical Research Foundation | Spin trap nitronyl hindered phenols |
US5488145A (en) | 1993-12-23 | 1996-01-30 | Oklahoma Medical Research Foundation | 2,4-disulfonyl phenyl butyl nitrone, its salts, and their use as pharmaceutical free radical traps |
WO1997019054A1 (en) | 1995-11-17 | 1997-05-29 | Florida International University | Azulenyl nitrone spin trapping agents, methods of making and using same |
TW429241B (en) | 1996-09-26 | 2001-04-11 | Sumitomo Pharma | Nitrone derivatives |
-
1997
- 1997-07-14 EP EP97933350A patent/EP1021430A1/en not_active Withdrawn
- 1997-07-14 WO PCT/US1997/011960 patent/WO1998003496A1/en not_active Application Discontinuation
- 1997-07-14 JP JP10506980A patent/JP2000514822A/ja active Pending
- 1997-07-14 IL IL12807097A patent/IL128070A0/xx unknown
- 1997-07-14 KR KR1019997000372A patent/KR20000067915A/ko not_active Application Discontinuation
- 1997-07-14 NZ NZ333705A patent/NZ333705A/xx unknown
- 1997-07-14 CA CA002260825A patent/CA2260825A1/en not_active Abandoned
- 1997-07-14 US US09/230,065 patent/US6376540B1/en not_active Expired - Fee Related
- 1997-07-14 AU AU36555/97A patent/AU715226B2/en not_active Ceased
- 1997-07-15 HR HR60/022,169A patent/HRP970381A2/hr not_active Application Discontinuation
- 1997-07-16 MA MA24719A patent/MA26434A1/fr unknown
- 1997-07-17 US US08/895,968 patent/US5942507A/en not_active Expired - Fee Related
- 1997-07-18 AR ARP970103231A patent/AR008781A1/es unknown
- 1997-07-18 ID IDP972489A patent/ID19679A/id unknown
- 1997-07-18 TN TNTNSN97125A patent/TNSN97125A1/fr unknown
- 1997-07-18 CO CO97040897A patent/CO4910142A1/es unknown
- 1997-07-18 ZA ZA9706388A patent/ZA976388B/xx unknown
-
1999
- 1999-05-24 US US09/317,267 patent/US6040444A/en not_active Expired - Fee Related
- 1999-05-24 US US09/317,266 patent/US6051571A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ID19679A (id) | 1998-07-30 |
ZA976388B (en) | 1998-02-19 |
HRP970381A2 (en) | 1998-08-31 |
US6051571A (en) | 2000-04-18 |
MA26434A1 (fr) | 2004-12-20 |
US5942507A (en) | 1999-08-24 |
NZ333705A (en) | 2000-09-29 |
CO4910142A1 (es) | 2000-04-24 |
WO1998003496A1 (en) | 1998-01-29 |
JP2000514822A (ja) | 2000-11-07 |
US6376540B1 (en) | 2002-04-23 |
AU715226B2 (en) | 2000-01-20 |
US6040444A (en) | 2000-03-21 |
EP1021430A1 (en) | 2000-07-26 |
CA2260825A1 (en) | 1998-01-29 |
AU3655597A (en) | 1998-02-10 |
TNSN97125A1 (fr) | 2005-03-15 |
KR20000067915A (ko) | 2000-11-25 |
IL128070A0 (en) | 1999-11-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2144192T3 (es) | Nuevos derivados de 1-fenil-2-dimetil-amino-metil-ciclohexan-1-ol, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. | |
AR001413A1 (es) | Compuestos triciclicos de carbamato, utiles para la inhibición de la función de la proteina g y paratratamiento de enfermedades proliferativas. | |
GT199700079A (es) | Derivados triciclos sustituidos con fenilamino | |
ECSP055609A (es) | "Uso de inhibidores de la IkB-quinasa para el tratamiento del dolor" | |
AR025960A1 (es) | Biblioteca de sustancias que contiene imidazo-5-il-aminas biciclicas y/o imidazo 3-il-aminas biciclicas, procedimiento para la preparacion de estabiblioteca de sustancias, y uso de sustancias de esta biblioteca para la preparacion de medicamentos para el tratamiento del dolor | |
CR6392A (es) | Moduladores de ccr5 | |
ES2145774T3 (es) | Derivados de adenosina que tienen actividad agonista en a2. | |
AR008781A1 (es) | Compuestos de furano nitrona | |
GT199700089A (es) | Derivados 6.6 o 6.7 -biciclicos sustituidos que contienen pirido o pirimido. | |
PA8468401A1 (es) | Compuestos para el tratamiento de la isquemia | |
ES2058185T3 (es) | Derivados de camptotecina y procedimiento para su preparacion. | |
ES2186783T3 (es) | Derivados de la dolastatina, su preparacion y uso. | |
SV1999000016A (es) | Derivados de 2-(purin-9-il-tetrahidrofuran-3,4-diol ref. pg3443/sv | |
SV1996000114A (es) | Nuevos plaguicidas | |
ES2157027T3 (es) | Oxazolidinonas sustituidas y su uso como farmacos antibacterianos. | |
ES2075050T3 (es) | Peptidos que tienen actividad cooperadora de celulas t. | |
ES2037013T3 (es) | Procedimiento para preparar tieno-1,4-diazepinas. | |
ES2158327T3 (es) | Derivados de benzo(g)quinolina. | |
ECSP034442A (es) | Mezclas de polisacaridos derivados de la heparina, su preparacion y las composiciones farmaceuticas que las contienen | |
ES2163538T3 (es) | Derivados de 3-oxo y 3-tioxo-4-aza-androstano diastereomericamente puros y su uso como antiandrogenos. | |
AR018162A1 (es) | Pirroles substituidos, composicion farmaceutica y el uso de los mismos para la preparacion de dicha composicion farmaceutica | |
ES2183923T3 (es) | Derivados de cromona. | |
AR020563A1 (es) | Compuestos (poli)tia-alquinoicos y sus derivados, composiciones que los incluyen y su utilizacion | |
AR028947A1 (es) | Compuestos novedosos | |
ES2140672T3 (es) | Compuestos biciclicos sustituidos, fusionados y puentes utilizados como agentes terapeuticos. |