IL128070A0 - Furan nitrone compounds - Google Patents
Furan nitrone compoundsInfo
- Publication number
- IL128070A0 IL128070A0 IL12807097A IL12807097A IL128070A0 IL 128070 A0 IL128070 A0 IL 128070A0 IL 12807097 A IL12807097 A IL 12807097A IL 12807097 A IL12807097 A IL 12807097A IL 128070 A0 IL128070 A0 IL 128070A0
- Authority
- IL
- Israel
- Prior art keywords
- nitrone compounds
- furan nitrone
- furan
- compounds
- nitrone
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/64—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2216996P | 1996-07-19 | 1996-07-19 | |
| PCT/US1997/011960 WO1998003496A1 (en) | 1996-07-19 | 1997-07-14 | Furan nitrone compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL128070A0 true IL128070A0 (en) | 1999-11-30 |
Family
ID=21808169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12807097A IL128070A0 (en) | 1996-07-19 | 1997-07-14 | Furan nitrone compounds |
Country Status (16)
| Country | Link |
|---|---|
| US (4) | US6376540B1 (es) |
| EP (1) | EP1021430A1 (es) |
| JP (1) | JP2000514822A (es) |
| KR (1) | KR20000067915A (es) |
| AR (1) | AR008781A1 (es) |
| AU (1) | AU715226B2 (es) |
| CA (1) | CA2260825A1 (es) |
| CO (1) | CO4910142A1 (es) |
| HR (1) | HRP970381A2 (es) |
| ID (1) | ID19679A (es) |
| IL (1) | IL128070A0 (es) |
| MA (1) | MA26434A1 (es) |
| NZ (1) | NZ333705A (es) |
| TN (1) | TNSN97125A1 (es) |
| WO (1) | WO1998003496A1 (es) |
| ZA (1) | ZA976388B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW429241B (en) * | 1996-09-26 | 2001-04-11 | Sumitomo Pharma | Nitrone derivatives |
| WO1999036415A1 (en) * | 1998-01-16 | 1999-07-22 | Centaur Pharmaceuticals, Inc. | Thioether furan nitrone compounds |
| AU2226999A (en) * | 1998-01-16 | 1999-08-02 | Renovis, Inc. | Thiophene nitrone compounds |
| WO1999059579A1 (en) * | 1998-05-19 | 1999-11-25 | Centaur Pharmaceuticals, Inc. | Furan nitrone therapeutics for the treatment of inflammatory bowel disease |
| EP1098873B1 (en) | 1998-07-17 | 2004-05-26 | Renovis, Inc. | Alpha-(2-hydroxyphenyl)nitrone compounds, pharmaceutical compositons containing the same and their use for treating inflammation |
| US6730700B2 (en) * | 1998-12-02 | 2004-05-04 | Renovis, Inc. | 3,4,5,-trisubstituted aryl nitrone compounds and pharmaceutical compositions containing the same |
| UA66401C2 (en) | 1998-12-02 | 2004-05-17 | Sentor Pharmaceuticals Inc | 3,4,5-trisubstituted aryl nitrone compounds and pharmaceutical composition containing the same |
| AU2003278565A1 (en) * | 2002-10-25 | 2004-05-13 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Steroid compounds comprising superoxide dismutase mimic groups and nitric oxide donor groups, and their use in the preparation of medicaments |
| US20060166894A1 (en) * | 2002-11-29 | 2006-07-27 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Ace-inhibitors having antioxidant and no-donor activity |
| US20050059638A1 (en) * | 2003-08-04 | 2005-03-17 | Kelly Michael G. | Aryl, heteroaromatic and bicyclic aryl nitrone compounds, prodrugs and pharmaceutical compositions of the same to treat human disorders |
| US20050182060A1 (en) * | 2004-02-13 | 2005-08-18 | Kelly Michael G. | 2-Substituted and 4-substituted aryl nitrone compounds |
| US9034926B2 (en) | 2010-12-30 | 2015-05-19 | Nicholas V. Perricone | Topical nitrone spin trap compositions for psoriasis |
| US8986739B2 (en) | 2011-02-28 | 2015-03-24 | Nicholas V. Perricone | Treatment of urinary incontinence using nitrone spin traps |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3666754A (en) | 1965-11-06 | 1972-05-30 | Dainippon Pharmaceutical Co | 2-(5-nitrofuryl) nitrone derivatives |
| US3988159A (en) | 1967-07-28 | 1976-10-26 | American Can Company | Light-sensitive material containing nitrone for forming heat-fixed images |
| US3834073A (en) | 1971-05-03 | 1974-09-10 | Scm Corp | Phenyl nitrone derivatives useful as seed protectants |
| US3849934A (en) | 1971-05-03 | 1974-11-26 | Scm Corp | Alpha-aryl-n-lower alkyl nitrone-containing compositions useful as anti-fungal agents |
| US3950327A (en) | 1972-09-19 | 1976-04-13 | Ciba-Geigy Corporation | New nitrones, their manufacture and their use for the manufacture of n-substituted araliphatic aldehyde-nitrones |
| US3917700A (en) | 1974-01-30 | 1975-11-04 | Goodyear Tire & Rubber | Nitrone compounds |
| US3903049A (en) | 1974-01-30 | 1975-09-02 | Goodyear Tire & Rubber | Oxidation resistant sulfur curable rubbery polymers |
| GB1588417A (en) | 1977-03-15 | 1981-04-23 | Agfa Gevaert | Photoresist materials |
| US4153722A (en) | 1977-10-06 | 1979-05-08 | William H. Rorer, Inc. | Method of treatment |
| GB2137619A (en) | 1983-03-30 | 1984-10-10 | Gerald Scott | Nitrone compounds and stabilised rubber compositions containing them |
| US5723502A (en) | 1985-07-18 | 1998-03-03 | Proctor; Peter H. | Topical spin trap composition and method |
| US5352442A (en) | 1985-07-18 | 1994-10-04 | Proctor Peter H | Topical tempo |
| US4871862A (en) | 1986-08-27 | 1989-10-03 | Fisons Corporation | α-Substituted ketonitrone derivatives |
| US4803282A (en) | 1986-08-27 | 1989-02-07 | Pennwalt Corporation | Alpha-substituted ketonitrone derivatives |
| ATE110954T1 (de) | 1988-01-29 | 1994-09-15 | Peter H Proctor | Haarwachstumanregung mit nitroxyd und anderen radikalen. |
| EP0496796B1 (en) * | 1989-10-17 | 1994-08-31 | Oklahoma Medical Research Foundation | Method and compositions for inhibition of disorders associated with oxidative damage |
| EP0590072B1 (en) * | 1991-06-18 | 2001-12-05 | Oklahoma Medical Research Foundation | Use of spin trapping for the treatment of diseases associated with oxidation of lipids and proteins |
| US5292746A (en) | 1991-09-12 | 1994-03-08 | Merrell Dow Pharmaceuticals Inc. | Cyclic nitrones, pharmaceutical compositions thereof and their use in treating shock |
| GB9300894D0 (en) | 1992-02-07 | 1993-03-10 | Zeneca Ltd | Oxime derivatives |
| US5455272A (en) | 1993-10-22 | 1995-10-03 | Oklahoma Medical Research Foundation | Spin trap nitronyl hindered phenols |
| US5488145A (en) | 1993-12-23 | 1996-01-30 | Oklahoma Medical Research Foundation | 2,4-disulfonyl phenyl butyl nitrone, its salts, and their use as pharmaceutical free radical traps |
| JP3887020B2 (ja) | 1995-11-17 | 2007-02-28 | フロリダ インターナショナル ユニバーシティー | アズレニルニトロンスピントラッピング剤、ならびにその製造方法および使用方法 |
| TW429241B (en) | 1996-09-26 | 2001-04-11 | Sumitomo Pharma | Nitrone derivatives |
-
1997
- 1997-07-14 KR KR1019997000372A patent/KR20000067915A/ko not_active Application Discontinuation
- 1997-07-14 US US09/230,065 patent/US6376540B1/en not_active Expired - Fee Related
- 1997-07-14 EP EP97933350A patent/EP1021430A1/en not_active Withdrawn
- 1997-07-14 JP JP10506980A patent/JP2000514822A/ja active Pending
- 1997-07-14 NZ NZ333705A patent/NZ333705A/xx unknown
- 1997-07-14 AU AU36555/97A patent/AU715226B2/en not_active Ceased
- 1997-07-14 IL IL12807097A patent/IL128070A0/xx unknown
- 1997-07-14 CA CA002260825A patent/CA2260825A1/en not_active Abandoned
- 1997-07-14 WO PCT/US1997/011960 patent/WO1998003496A1/en not_active Application Discontinuation
- 1997-07-15 HR HR60/022,169A patent/HRP970381A2/hr not_active Application Discontinuation
- 1997-07-16 MA MA24719A patent/MA26434A1/fr unknown
- 1997-07-17 US US08/895,968 patent/US5942507A/en not_active Expired - Fee Related
- 1997-07-18 ID IDP972489A patent/ID19679A/id unknown
- 1997-07-18 CO CO97040897A patent/CO4910142A1/es unknown
- 1997-07-18 AR ARP970103231A patent/AR008781A1/es unknown
- 1997-07-18 ZA ZA9706388A patent/ZA976388B/xx unknown
- 1997-07-18 TN TNTNSN97125A patent/TNSN97125A1/fr unknown
-
1999
- 1999-05-24 US US09/317,266 patent/US6051571A/en not_active Expired - Fee Related
- 1999-05-24 US US09/317,267 patent/US6040444A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5942507A (en) | 1999-08-24 |
| NZ333705A (en) | 2000-09-29 |
| AR008781A1 (es) | 2000-02-23 |
| ID19679A (id) | 1998-07-30 |
| JP2000514822A (ja) | 2000-11-07 |
| EP1021430A1 (en) | 2000-07-26 |
| MA26434A1 (fr) | 2004-12-20 |
| AU3655597A (en) | 1998-02-10 |
| WO1998003496A1 (en) | 1998-01-29 |
| CO4910142A1 (es) | 2000-04-24 |
| KR20000067915A (ko) | 2000-11-25 |
| TNSN97125A1 (fr) | 2005-03-15 |
| US6040444A (en) | 2000-03-21 |
| HRP970381A2 (en) | 1998-08-31 |
| ZA976388B (en) | 1998-02-19 |
| AU715226B2 (en) | 2000-01-20 |
| US6051571A (en) | 2000-04-18 |
| US6376540B1 (en) | 2002-04-23 |
| CA2260825A1 (en) | 1998-01-29 |
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