ES2163538T3 - Derivados de 3-oxo y 3-tioxo-4-aza-androstano diastereomericamente puros y su uso como antiandrogenos. - Google Patents

Derivados de 3-oxo y 3-tioxo-4-aza-androstano diastereomericamente puros y su uso como antiandrogenos.

Info

Publication number
ES2163538T3
ES2163538T3 ES95942689T ES95942689T ES2163538T3 ES 2163538 T3 ES2163538 T3 ES 2163538T3 ES 95942689 T ES95942689 T ES 95942689T ES 95942689 T ES95942689 T ES 95942689T ES 2163538 T3 ES2163538 T3 ES 2163538T3
Authority
ES
Spain
Prior art keywords
tioxo
androstan
antiandrogens
aza
oxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95942689T
Other languages
English (en)
Inventor
Stefano Poli
Roberto Girardello
Paride Grisenti
Ambrogio Magni
Vincenzo Olgiati
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Polichem SA
Original Assignee
Polichem SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Polichem SA filed Critical Polichem SA
Application granted granted Critical
Publication of ES2163538T3 publication Critical patent/ES2163538T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

COMPUESTOS DE FORMULA (A) DONDE LOS GRUPOS X, R 1 E Y SON LOS DEFINIDOS, QUE TIENEN ACTIVIDAD FARMACOLOGICA, Y USO DE LOS MISMOS COMO AGENTES ANTIANDROGENOS.
ES95942689T 1994-12-23 1995-12-18 Derivados de 3-oxo y 3-tioxo-4-aza-androstano diastereomericamente puros y su uso como antiandrogenos. Expired - Lifetime ES2163538T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI942626A IT1271325B (it) 1994-12-23 1994-12-23 Composti diastereomericamente puri derivati da 3-oxo e 3-tioxo-4-azaandrostani e loro uso come antiandrogeni

Publications (1)

Publication Number Publication Date
ES2163538T3 true ES2163538T3 (es) 2002-02-01

Family

ID=11370067

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95942689T Expired - Lifetime ES2163538T3 (es) 1994-12-23 1995-12-18 Derivados de 3-oxo y 3-tioxo-4-aza-androstano diastereomericamente puros y su uso como antiandrogenos.

Country Status (10)

Country Link
US (1) US6147213A (es)
EP (1) EP0799239B1 (es)
AT (1) ATE207929T1 (es)
AU (1) AU4387296A (es)
DE (1) DE69523622T2 (es)
DK (1) DK0799239T3 (es)
ES (1) ES2163538T3 (es)
IT (1) IT1271325B (es)
PT (1) PT799239E (es)
WO (1) WO1996020210A2 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6645974B2 (en) 2001-07-31 2003-11-11 Merck & Co., Inc. Androgen receptor modulators and methods for use thereof
KR101496934B1 (ko) 2006-11-15 2015-03-03 유니버시티 오브 워싱톤 스루 이츠 센터 포 커머셜리제이션 전기 이중층 캐패시턴스 장치
JP5456669B2 (ja) * 2007-05-03 2014-04-02 エール ユニヴァーシティ 局所活性「ソフト」抗アンドロゲン剤
FI2448748T3 (fi) 2009-07-01 2024-10-09 Basf Mobile Emissions Catalysts Llc Ultrapuhtaita synteettisiä hiilimateriaaleja
CN102823037A (zh) * 2009-12-11 2012-12-12 艾纳G2技术公司 含电化学改性剂的碳材料
US8916296B2 (en) 2010-03-12 2014-12-23 Energ2 Technologies, Inc. Mesoporous carbon materials comprising bifunctional catalysts
CN103261090A (zh) 2010-09-30 2013-08-21 艾纳G2技术公司 储能颗粒的增强式装填
CN108538625B (zh) 2010-12-28 2020-12-08 巴斯福股份公司 包含增强的电化学特性的碳材料
US20120262127A1 (en) 2011-04-15 2012-10-18 Energ2 Technologies, Inc. Flow ultracapacitor
CN103947017B (zh) 2011-06-03 2017-11-17 巴斯福股份公司 用于混合能量存储装置中的碳‑铅共混物
US9409777B2 (en) 2012-02-09 2016-08-09 Basf Se Preparation of polymeric resins and carbon materials
CN105190948B (zh) 2013-03-14 2019-04-26 14族科技公司 包含锂合金化的电化学改性剂的复合碳材料
US10195583B2 (en) 2013-11-05 2019-02-05 Group 14 Technologies, Inc. Carbon-based compositions with highly efficient volumetric gas sorption
WO2015137980A1 (en) 2014-03-14 2015-09-17 Energ2 Technologies, Inc. Novel methods for sol-gel polymerization in absence of solvent and creation of tunable carbon structure from same
WO2017031006A1 (en) 2015-08-14 2017-02-23 Energ2 Technologies, Inc. Composites of porous nano-featured silicon materials and carbon materials
KR102637617B1 (ko) 2015-08-28 2024-02-19 그룹14 테크놀로지스, 인코포레이티드 극도로 내구성이 우수한 리튬 인터칼레이션을 나타내는 신규 물질 및 그의 제조 방법
CN110582823A (zh) 2017-03-09 2019-12-17 14集团技术公司 含硅前体在多孔支架材料上的分解
US11639292B2 (en) 2020-08-18 2023-05-02 Group14 Technologies, Inc. Particulate composite materials
US11174167B1 (en) 2020-08-18 2021-11-16 Group14 Technologies, Inc. Silicon carbon composites comprising ultra low Z
US11335903B2 (en) 2020-08-18 2022-05-17 Group14 Technologies, Inc. Highly efficient manufacturing of silicon-carbon composites materials comprising ultra low z
KR20230082028A (ko) 2020-09-30 2023-06-08 그룹14 테크놀로지스, 인코포레이티드 규소-탄소 복합재의 산소 함량 및 반응성을 제어하기 위한 부동태화의 방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4845104A (en) * 1986-11-20 1989-07-04 Merck & Co., Inc. Oxidized analogs of 17β-N-monosubstituted-carbamoyl-4-aza-5-α-androstan-3-ones
IE76452B1 (en) * 1990-10-29 1997-10-22 Sankyo Co Azasteroid compounds for the treatment of prostatic hypertrophy their preparation and use
GB9216329D0 (en) * 1992-07-31 1992-09-16 Erba Carlo Spa 17beta-substituted 4-aza-5alpha-androstan-3-one derivatives

Also Published As

Publication number Publication date
WO1996020210A2 (en) 1996-07-04
US6147213A (en) 2000-11-14
ITMI942626A1 (it) 1996-06-23
EP0799239A2 (en) 1997-10-08
PT799239E (pt) 2002-02-28
DE69523622D1 (de) 2001-12-06
EP0799239B1 (en) 2001-10-31
ITMI942626A0 (it) 1994-12-23
IT1271325B (it) 1997-05-27
AU4387296A (en) 1996-07-19
ATE207929T1 (de) 2001-11-15
DK0799239T3 (da) 2001-12-10
WO1996020210A3 (en) 1996-09-06
DE69523622T2 (de) 2002-05-29

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