TNSN90066A1 - Nouveaux procedes d'obtention de 6-methyl 19-nor steroides et leur conversion en 19-nor pregnadienes 17 substitues - Google Patents

Nouveaux procedes d'obtention de 6-methyl 19-nor steroides et leur conversion en 19-nor pregnadienes 17 substitues

Info

Publication number
TNSN90066A1
TNSN90066A1 TNTNSN90066A TNSN90066A TNSN90066A1 TN SN90066 A1 TNSN90066 A1 TN SN90066A1 TN TNSN90066 A TNTNSN90066 A TN TNSN90066A TN SN90066 A TNSN90066 A TN SN90066A TN SN90066 A1 TNSN90066 A1 TN SN90066A1
Authority
TN
Tunisia
Prior art keywords
methyl
steroids
obtaining
pregnadian
substituted
Prior art date
Application number
TNTNSN90066A
Other languages
English (en)
Inventor
Claude Tchernatinsky
Nejib Mohamed Nasraoui
Alain Piasco
Original Assignee
Theramex
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theramex filed Critical Theramex
Publication of TNSN90066A1 publication Critical patent/TNSN90066A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0055—Estrane derivatives not substituted in position 17

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)

Abstract

L'INVENTION SE RAPPORTE AU DOMAINE DE LA CHIMIE ORGANIQUE ET PLUS PARTICULIEREMENT A LA CHIMIE DES STEROIDES. ELLE A PLUS PARTICULIEREMENT POUR OBJET DE NOUVEAUX 6-METHYL ESTRA 4,6-DIENES DE FORMULE GENERALE I, DANS LAQUELLE A REPRESENTE DE L'HYDROGENE OU UN RADICAL OXOALCOYLE INFERIEUR. ET B REPRESENTE DE L'HYDROGENE. OU BIEN A EST UN HYDROXYLE LIBRE OU ESTERIFIE, ET B EST UN RADICAL ALCOYLE INFERIEUR OU UN RADICAL ALCYNYLE INFERIEUR OU BIEN A ET B FORMENT ENSEMBLE L'OXYGENE D'UNE CETONE. CETTE INVENTION A EGALEMENT POUR OBJET UN PROCEDE D'OBTENTION DES COMPOSES DE FORMULE GENERALE I CES COMPOSES SONT DES INTERMEDIAIRES DE SYNTHESE PRECIEUX QUI PERMETTENT L'ACCES A DES 6-METHYL 19-NOR PREGNA 4,6-DIENES PHARMACOLOGIQUEMENT-ACTIFS
TNTNSN90066A 1989-05-24 1990-05-23 Nouveaux procedes d'obtention de 6-methyl 19-nor steroides et leur conversion en 19-nor pregnadienes 17 substitues TNSN90066A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8906790A FR2647452A1 (fr) 1989-05-24 1989-05-24 Nouveaux 19-nor steroides 6-methyles leurs procedes d'obtention, les compositions pharmaceutiques en renfermant et leur conversion en 19-nor pregnadienes 17-substitues

Publications (1)

Publication Number Publication Date
TNSN90066A1 true TNSN90066A1 (fr) 1991-03-05

Family

ID=9381962

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN90066A TNSN90066A1 (fr) 1989-05-24 1990-05-23 Nouveaux procedes d'obtention de 6-methyl 19-nor steroides et leur conversion en 19-nor pregnadienes 17 substitues

Country Status (12)

Country Link
EP (1) EP0431107A1 (fr)
JP (1) JPH04503362A (fr)
KR (1) KR920701231A (fr)
AU (1) AU643218B2 (fr)
FI (1) FI910351A0 (fr)
FR (1) FR2647452A1 (fr)
GR (1) GR900100394A (fr)
HU (1) HU209590B (fr)
MA (1) MA21851A1 (fr)
PT (1) PT94134A (fr)
TN (1) TNSN90066A1 (fr)
WO (1) WO1990015067A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2679236B1 (fr) * 1991-07-18 1997-01-24 Theramex Nouveaux sterouides substitues en position 6, leurs procedes d'obtention et des compositions pharmaceutiques en renfermant.
US20050009797A1 (en) * 2001-12-19 2005-01-13 Mitsuaki Nakamura Androstane derivative having substituent in 7- abd 17--positions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE641817A (fr) * 1963-02-28
JPS504657B1 (fr) * 1968-07-30 1975-02-22
DE3204281C1 (de) * 1982-02-05 1983-07-21 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 6-Methyl-delta?-3-ketosteroiden
DE3346204A1 (de) * 1983-12-21 1985-07-11 Council Of Scientific And Industrial Research, New Delhi Verfahren zur herstellung von 17ss-((l-oxoheptyl)oxy)19-norpregn-4-en-20-in-3on norethisteronoenanthat) und estern davon und diese enthaltende arzneimittel
FR2576025B1 (fr) * 1985-01-14 1987-01-23 Roussel Uclaf Nouveaux steroides substitues en position 10, leur procede et les intermediaires de preparation, leur application comme medicaments, les compositions pharmaceutiques les contenant
CN1008820B (zh) * 1985-05-10 1990-07-18 施林工业产权保护股份公司 17α-乙炔基-17β-羟基-18-甲基-4，15-雌甾二烯-3-酮的制备方法

Also Published As

Publication number Publication date
FI910351A0 (fi) 1991-01-23
PT94134A (pt) 1991-01-08
EP0431107A1 (fr) 1991-06-12
HU209590B (en) 1994-08-29
JPH04503362A (ja) 1992-06-18
HU905221D0 (en) 1991-07-29
AU5742690A (en) 1991-01-07
FR2647452A1 (fr) 1990-11-30
WO1990015067A2 (fr) 1990-12-13
WO1990015067A3 (fr) 1991-01-24
AU643218B2 (en) 1993-11-11
MA21851A1 (fr) 1990-12-31
GR900100394A (el) 1991-10-10
HUT59154A (en) 1992-04-28
KR920701231A (ko) 1992-08-11

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