TNSN87085A1 - Derives de 4-(aroylamino) piperidinebutanamide, leur procede de preparation et leur application en tant qu'antidiarrheique - Google Patents

Derives de 4-(aroylamino) piperidinebutanamide, leur procede de preparation et leur application en tant qu'antidiarrheique

Info

Publication number
TNSN87085A1
TNSN87085A1 TNTNSN87085A TNSN87085A TNSN87085A1 TN SN87085 A1 TNSN87085 A1 TN SN87085A1 TN TNSN87085 A TNTNSN87085 A TN TNSN87085A TN SN87085 A TNSN87085 A TN SN87085A TN SN87085 A1 TNSN87085 A1 TN SN87085A1
Authority
TN
Tunisia
Prior art keywords
antidiarrhoic
piperidinebutanamide
aroylamino
derivatives
preparation
Prior art date
Application number
TNTNSN87085A
Other languages
English (en)
Inventor
Francois Vlaeminck Freddy
Maria Sommen Francois
Anna Josef De Cleyn Michel
Henri Paul Van Daele Georges
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of TNSN87085A1 publication Critical patent/TNSN87085A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'INVENTION VISE PLUS PARTICULIEREMENT LES COMPOSES DE FORMULE GENERALE I . SES FORMES N-OXYDE, SES SELS D'ADDITION D'ACIDES PHARMACEUTIQUEMENT ACCEPTABLES ET SES FORMES STEREOISOMERIQUES POSSIBLES.
TNTNSN87085A 1986-07-03 1987-07-02 Derives de 4-(aroylamino) piperidinebutanamide, leur procede de preparation et leur application en tant qu'antidiarrheique TNSN87085A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US88206786A 1986-07-03 1986-07-03

Publications (1)

Publication Number Publication Date
TNSN87085A1 true TNSN87085A1 (fr) 1990-01-01

Family

ID=25379820

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN87085A TNSN87085A1 (fr) 1986-07-03 1987-07-02 Derives de 4-(aroylamino) piperidinebutanamide, leur procede de preparation et leur application en tant qu'antidiarrheique

Country Status (25)

Country Link
EP (1) EP0251417B1 (fr)
JP (1) JP2512755B2 (fr)
KR (1) KR960009422B1 (fr)
CN (1) CN87104641A (fr)
AT (1) ATE88181T1 (fr)
AU (1) AU593660B2 (fr)
BG (1) BG80406A (fr)
CA (1) CA1311755C (fr)
DE (1) DE3785393T2 (fr)
DK (1) DK336387A (fr)
ES (1) ES2054653T3 (fr)
FI (1) FI90863C (fr)
HU (1) HU204254B (fr)
IE (1) IE60342B1 (fr)
IL (1) IL83045A (fr)
MA (1) MA21026A1 (fr)
NO (1) NO171908C (fr)
NZ (1) NZ220779A (fr)
PH (1) PH26678A (fr)
PT (1) PT85232B (fr)
SU (1) SU1620049A3 (fr)
TN (1) TNSN87085A1 (fr)
ZA (1) ZA874810B (fr)
ZM (1) ZM5487A1 (fr)
ZW (1) ZW12187A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ225152A (en) * 1987-07-17 1990-04-26 Janssen Pharmaceutica Nv Heterocyclically substituted piperidinyl benzamides as pharmaceuticals
US5130312A (en) * 1987-07-17 1992-07-14 Janssen Pharmaceutica N.V. Substituted N-(3-hydroxy-4-piperidinyl)benzamides
CA1317940C (fr) * 1987-09-25 1993-05-18 Georges H. P. Van Daele N-(1-alkyl-3-hydroxy-4-piperidinyl) benzamides a substituant
US4975439A (en) * 1987-09-25 1990-12-04 Janssen Pharmaceutical N.V. Novel substituted N-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides
US5041454A (en) * 1987-09-25 1991-08-20 Janssen Pharmaceutica N.V. Novel substituted N-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides
TW294595B (fr) * 1992-11-20 1997-01-01 Janssen Pharmaceutica Nv
JP3235913B2 (ja) * 1993-07-30 2001-12-04 エーザイ株式会社 アミノ安息香酸誘導体
US5585387A (en) * 1994-10-07 1996-12-17 Torcan Chemical Ltd. Prepration of cisapride
RU2008139599A (ru) 2006-03-07 2010-04-20 Эррэй Биофарма Инк. (Us) Гетеробициклические производные пиразола и способы их применения

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1183847A (fr) * 1981-10-01 1985-03-12 Georges Van Daele N-(3-hydroxy-4-piperidinyl)benzamide; derives

Also Published As

Publication number Publication date
HU204254B (en) 1991-12-30
IE60342B1 (en) 1994-06-29
KR880001593A (ko) 1988-04-25
MA21026A1 (fr) 1988-04-01
IE871766L (en) 1988-01-03
DK336387A (da) 1988-01-04
EP0251417A3 (en) 1989-04-26
JP2512755B2 (ja) 1996-07-03
ATE88181T1 (de) 1993-04-15
DE3785393D1 (de) 1993-05-19
FI872930A (fi) 1988-01-04
ES2054653T3 (es) 1994-08-16
CA1311755C (fr) 1992-12-22
NZ220779A (en) 1989-09-27
IL83045A0 (en) 1987-12-31
FI90863B (fi) 1993-12-31
ZW12187A1 (en) 1989-02-01
PT85232B (pt) 1990-03-30
NO872781D0 (no) 1987-07-02
PT85232A (pt) 1987-08-01
PH26678A (en) 1992-09-15
AU593660B2 (en) 1990-02-15
BG80406A (bg) 1993-12-24
EP0251417A2 (fr) 1988-01-07
NO872781L (no) 1988-01-04
KR960009422B1 (en) 1996-07-19
CN87104641A (zh) 1988-02-03
ZA874810B (en) 1989-02-22
AU7506787A (en) 1988-01-07
FI872930A0 (fi) 1987-07-02
IL83045A (en) 1991-07-18
DK336387D0 (da) 1987-06-30
EP0251417B1 (fr) 1993-04-14
DE3785393T2 (de) 1993-07-29
NO171908B (no) 1993-02-08
JPS6322575A (ja) 1988-01-30
NO171908C (no) 1993-05-19
HUT48588A (en) 1989-06-28
SU1620049A3 (ru) 1991-01-07
ZM5487A1 (en) 1988-06-27
FI90863C (fi) 1994-04-11

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