DE3785393D1 - 4-(aroylamino)piperidinbutanamide derivate. - Google Patents

4-(aroylamino)piperidinbutanamide derivate.

Info

Publication number
DE3785393D1
DE3785393D1 DE8787201255T DE3785393T DE3785393D1 DE 3785393 D1 DE3785393 D1 DE 3785393D1 DE 8787201255 T DE8787201255 T DE 8787201255T DE 3785393 T DE3785393 T DE 3785393T DE 3785393 D1 DE3785393 D1 DE 3785393D1
Authority
DE
Germany
Prior art keywords
formula
compounds
aroylamino
chem
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787201255T
Other languages
English (en)
Other versions
DE3785393T2 (de
Inventor
Daele Georges Henri Paul Van
Freddy Francois Vlaeminck
Francois Maria Sommen
Cleyn Michael Anna Jozef De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Publication of DE3785393D1 publication Critical patent/DE3785393D1/de
Application granted granted Critical
Publication of DE3785393T2 publication Critical patent/DE3785393T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE8787201255T 1986-07-03 1987-07-01 4-(aroylamino)piperidinbutanamide derivate. Expired - Fee Related DE3785393T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US88206786A 1986-07-03 1986-07-03

Publications (2)

Publication Number Publication Date
DE3785393D1 true DE3785393D1 (de) 1993-05-19
DE3785393T2 DE3785393T2 (de) 1993-07-29

Family

ID=25379820

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787201255T Expired - Fee Related DE3785393T2 (de) 1986-07-03 1987-07-01 4-(aroylamino)piperidinbutanamide derivate.

Country Status (24)

Country Link
EP (1) EP0251417B1 (de)
JP (1) JP2512755B2 (de)
KR (1) KR960009422B1 (de)
CN (1) CN87104641A (de)
AT (1) ATE88181T1 (de)
AU (1) AU593660B2 (de)
CA (1) CA1311755C (de)
DE (1) DE3785393T2 (de)
DK (1) DK336387A (de)
ES (1) ES2054653T3 (de)
FI (1) FI90863C (de)
HU (1) HU204254B (de)
IE (1) IE60342B1 (de)
IL (1) IL83045A (de)
MA (1) MA21026A1 (de)
NO (1) NO171908C (de)
NZ (1) NZ220779A (de)
PH (1) PH26678A (de)
PT (1) PT85232B (de)
SU (1) SU1620049A3 (de)
TN (1) TNSN87085A1 (de)
ZA (1) ZA874810B (de)
ZM (1) ZM5487A1 (de)
ZW (1) ZW12187A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5130312A (en) * 1987-07-17 1992-07-14 Janssen Pharmaceutica N.V. Substituted N-(3-hydroxy-4-piperidinyl)benzamides
NZ225152A (en) * 1987-07-17 1990-04-26 Janssen Pharmaceutica Nv Heterocyclically substituted piperidinyl benzamides as pharmaceuticals
CA1317940C (en) * 1987-09-25 1993-05-18 Georges H. P. Van Daele Substituted n-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides
US4975439A (en) * 1987-09-25 1990-12-04 Janssen Pharmaceutical N.V. Novel substituted N-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides
US5041454A (en) * 1987-09-25 1991-08-20 Janssen Pharmaceutica N.V. Novel substituted N-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides
TW294595B (de) * 1992-11-20 1997-01-01 Janssen Pharmaceutica Nv
JP3235913B2 (ja) * 1993-07-30 2001-12-04 エーザイ株式会社 アミノ安息香酸誘導体
US5585387A (en) * 1994-10-07 1996-12-17 Torcan Chemical Ltd. Prepration of cisapride
BRPI0708615A2 (pt) 2006-03-07 2011-06-07 Array Biopharma Inc compostos de pirazol heterobicìclicos e métodos de uso

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1183847A (en) * 1981-10-01 1985-03-12 Georges Van Daele N-(3-hydroxy-4-piperidinyl)benzamide derivatives

Also Published As

Publication number Publication date
NO872781D0 (no) 1987-07-02
HUT48588A (en) 1989-06-28
FI90863B (fi) 1993-12-31
DK336387A (da) 1988-01-04
AU593660B2 (en) 1990-02-15
EP0251417A3 (en) 1989-04-26
CN87104641A (zh) 1988-02-03
ZW12187A1 (en) 1989-02-01
FI90863C (fi) 1994-04-11
IE60342B1 (en) 1994-06-29
HU204254B (en) 1991-12-30
NO171908B (no) 1993-02-08
FI872930A (fi) 1988-01-04
MA21026A1 (fr) 1988-04-01
CA1311755C (en) 1992-12-22
EP0251417A2 (de) 1988-01-07
JPS6322575A (ja) 1988-01-30
DE3785393T2 (de) 1993-07-29
AU7506787A (en) 1988-01-07
SU1620049A3 (ru) 1991-01-07
ZM5487A1 (en) 1988-06-27
KR960009422B1 (en) 1996-07-19
NO872781L (no) 1988-01-04
IL83045A (en) 1991-07-18
PT85232B (pt) 1990-03-30
KR880001593A (ko) 1988-04-25
JP2512755B2 (ja) 1996-07-03
IE871766L (en) 1988-01-03
ZA874810B (en) 1989-02-22
FI872930A0 (fi) 1987-07-02
PH26678A (en) 1992-09-15
DK336387D0 (da) 1987-06-30
IL83045A0 (en) 1987-12-31
TNSN87085A1 (fr) 1990-01-01
NO171908C (no) 1993-05-19
ATE88181T1 (de) 1993-04-15
NZ220779A (en) 1989-09-27
PT85232A (pt) 1987-08-01
EP0251417B1 (de) 1993-04-14
ES2054653T3 (es) 1994-08-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee