TH86246A - - Google Patents
Info
- Publication number
- TH86246A TH86246A TH601003563A TH0601003563A TH86246A TH 86246 A TH86246 A TH 86246A TH 601003563 A TH601003563 A TH 601003563A TH 0601003563 A TH0601003563 A TH 0601003563A TH 86246 A TH86246 A TH 86246A
- Authority
- TH
- Thailand
- Prior art keywords
- alkyl
- replaced
- het
- choose
- cycloalkyl
- Prior art date
Links
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims abstract 26
- 125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 claims abstract 11
- 239000001257 hydrogen Substances 0.000 claims abstract 8
- 229910052739 hydrogen Inorganic materials 0.000 claims abstract 8
- 125000004435 hydrogen atoms Chemical group [H]* 0.000 claims abstract 8
- 239000000126 substance Substances 0.000 claims abstract 6
- 150000001875 compounds Chemical class 0.000 claims abstract 4
- 150000001204 N-oxides Chemical class 0.000 claims abstract 3
- 150000003839 salts Chemical class 0.000 claims abstract 3
- 239000011780 sodium chloride Substances 0.000 claims abstract 3
- 241000219289 Silene Species 0.000 claims abstract 2
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drugs Drugs 0.000 claims 1
- 125000004890 (C1-C6) alkylamino group Chemical group 0.000 abstract 4
- 125000003118 aryl group Chemical group 0.000 abstract 4
- 239000003112 inhibitor Substances 0.000 abstract 4
- 230000002401 inhibitory effect Effects 0.000 abstract 4
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 4
- 238000006467 substitution reaction Methods 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 3
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- MYMOFIZGZYHOMD-UHFFFAOYSA-N oxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- 239000011593 sulfur Substances 0.000 abstract 2
- 101710034456 MT-CO1 Proteins 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000036231 pharmacokinetics Effects 0.000 abstract 1
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH86246B TH86246B (th) | 2007-08-30 |
| TH86246A true TH86246A (fr) | 2007-08-30 |
Family
ID=
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| TH86246A (fr) | ||
| TH86246B (th) | ตัวยับยั้งที่เป็นแมโครไซคลิคของไวรัสตับอักเสบ c | |
| TH86247A (fr) | ||
| TH86641A (fr) | ||
| TH86431A (fr) | ||
| TH86247B (th) | ตัวยับยั้งที่เป็นแมโครไซคลิคของไวรัสตับอักเสบ c | |
| EA200801910A1 (ru) | Новые гетероциклические циклоалкильные соединения, способ их получения и фармацевтические композиции, которые их содержат | |
| TH86431B (th) | ตัวยับยั้งที่เป็นแมโครไซคลิคของไวรัสตับอักเสบ c | |
| TH86641B (th) | ตัวยับยั้งที่เป็นแมโครไซคลิคของไวรัสตับอักเสบ c |