SU417936A3 - - Google Patents

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Publication number
SU417936A3
SU417936A3 SU1739938A SU1739938A SU417936A3 SU 417936 A3 SU417936 A3 SU 417936A3 SU 1739938 A SU1739938 A SU 1739938A SU 1739938 A SU1739938 A SU 1739938A SU 417936 A3 SU417936 A3 SU 417936A3
Authority
SU
USSR - Soviet Union
Prior art keywords
hydrogen
naphthylalkylamines
general formula
indicated
catalyst
Prior art date
Application number
SU1739938A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Application granted granted Critical
Publication of SU417936A3 publication Critical patent/SU417936A3/ru

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Classifications

    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B33/00Silicon; Compounds thereof
    • C01B33/113Silicon oxides; Hydrates thereof
    • C01B33/12Silica; Hydrates thereof, e.g. lepidoic silicic acid
    • C01B33/14Colloidal silica, e.g. dispersions, gels, sols
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Amplifiers (AREA)

Description

СПОСОБ ПОЛУЧЕНИЯ НАФТИЛАЛКИЛАМИНОВ
1
Изобретение относитс  к способу получени  новых, не описанных в литературе нафтилалкиламинов , которые обладают фармакологической активностью и могут найти применение в медицине.
Известен способ получени  вторичных ароматических аминов взаимодействием первичных ароматических аминов с фенолом в присутствии катализатора, заключающийс  в том, что в качестве катализатора используют органические сульфокислоты, преимущественно ароматические сульфокислоты.
Предлагают способ получени  нафтилалкиламинов общей формулы
R,К,
-CH-NH.-CH-снI он
к
где В - алкилен с 1-4 атомами углерода;
RI - водород, низщий алкильный или алкокси-радикал или группа :::ОКб;
R2 и R4 - водород или низщий алкил или алкокси-радикал;
Кз - водород, метил или этил;
Rs - водород, группа OR6 или алкилсульфонамидный радикал;
Re - водород или низщий ацил;
Rg - водород или метил, обладающих ценными свойствами.
Предлагаемый способ получени  нафтилалкиламинов указанной формулы или их производных заключаетс  в том, что кетон общей формулы
2 .Б2,СВ- 0
где RI, R2, Rg и В имеют указанные значеОЕа ни ,
подвергают реакции обменного разложени  с RS амином общей формулы
Кз
-сн- 0
сн
I
он р
25 где Ra, R4, Rs и Re имеют указанные значени ,
в услови х восстановительного аминировани .
SU1739938A 1969-12-12 1970-12-11 SU417936A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1962497A DE1962497C3 (de) 1969-12-12 1969-12-12 Naphthylalkyl- a -hydroxyphenäthyl-amine, ihre Herstellung und diese enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
SU417936A3 true SU417936A3 (ru) 1974-02-28

Family

ID=5753745

Family Applications (2)

Application Number Title Priority Date Filing Date
SU1739938A SU417936A3 (ru) 1969-12-12 1970-12-11
SU1739939A SU505349A3 (ru) 1969-12-12 1970-12-11 Способ получени нафтилалкиламинов

Family Applications After (1)

Application Number Title Priority Date Filing Date
SU1739939A SU505349A3 (ru) 1969-12-12 1970-12-11 Способ получени нафтилалкиламинов

Country Status (25)

Country Link
US (1) US3966814A (ru)
JP (3) JPS5116420B1 (ru)
KR (2) KR780000007B1 (ru)
AR (2) AR194205A1 (ru)
AT (3) AT302284B (ru)
BE (1) BE760252A (ru)
BG (1) BG17956A3 (ru)
CH (1) CH556322A (ru)
CS (3) CS151062B2 (ru)
DE (1) DE1962497C3 (ru)
DK (1) DK136526B (ru)
ES (3) ES386345A1 (ru)
FI (1) FI53301C (ru)
FR (1) FR2081347B1 (ru)
GB (1) GB1330188A (ru)
HU (1) HU162736B (ru)
IE (1) IE34807B1 (ru)
IL (1) IL35840A (ru)
NL (1) NL169583C (ru)
NO (1) NO131126C (ru)
PL (3) PL81424B1 (ru)
RO (3) RO61063A (ru)
SE (1) SE378101B (ru)
SU (2) SU417936A3 (ru)
YU (3) YU35753B (ru)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2187319B1 (ru) * 1972-06-09 1975-06-20 Bottu Exploit Labo
GB1535435A (en) * 1975-12-11 1978-12-13 Tanabe Seiyaku Co Benzyl alcohol derivatives
JPS53149940A (en) * 1977-06-02 1978-12-27 Tanabe Seiyaku Co Ltd Novel benzyl alcohol derivatives and their preparation
US4849453A (en) * 1983-01-31 1989-07-18 Eli Lilly And Company Growth promotion
US5250546A (en) * 1984-09-28 1993-10-05 Nippon Chemiphar Co., Ltd. Amino-alcohol derivatives and processes for their preparation
DE3880628T2 (de) * 1987-11-13 1993-08-05 Glaxo Group Ltd Phenethanolamin-derivate.
US5194450A (en) * 1988-04-20 1993-03-16 Burroughs Wellcome Co. Anti-hypertensive sulfonanilides
GB8809314D0 (en) * 1988-04-20 1988-05-25 Wellcome Found Anti-hypertensive sulfonanilides
ATE359993T1 (de) * 1997-08-05 2007-05-15 Pola Chem Ind Inc Aminderivate, verfahren zu ihrer herstellung und ihre verwendung als antimykotische mittel
CA2558020A1 (en) 2004-03-17 2005-09-29 Novartis Ag Use of renin inhibitors in therapy
AU2013202127B2 (en) * 2006-08-10 2014-06-12 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Preparation of (R,R-)-fenoterol and (R,R)- or (R,S)-fenoterol analogues and their use in treating congestive heart failure
JP5302194B2 (ja) * 2006-08-10 2013-10-02 アメリカ合衆国 (r,r)−フェノテロールおよび(r,r)−または(r,s)−フェノテロール類似体の調製物ならびにうっ血性心不全の治療におけるそれらの使用
CA2791702C (en) 2010-03-10 2018-05-29 Sri International The use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas
JP6208031B2 (ja) * 2014-01-30 2017-10-04 東芝ライフスタイル株式会社 ブラシレスモータおよびその製造方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE894396C (de) * 1944-05-21 1953-10-26 Troponwerke Dinklage & Co Verfahren zur Herstellung von 1-(o-, m- oder p-Oxyphenyl)-1-oxy-2-aralkylamino-aethanen
US3135797A (en) * 1958-04-15 1964-06-02 Colgate Palmolive Co Aromatic amino antispasmodic compounds
US3139441A (en) * 1960-02-16 1964-06-30 Colgate Palmolive Co Alpha (3, 4 dihidroxy phenyl)-beta-(nu-3, 14'-methylenedioxy-phenyl)-alkylamino ethanols
NL300751A (ru) * 1962-11-30 1900-01-01
GB1059968A (en) * 1964-01-20 1967-02-22 Ici Ltd Naphthalene derivatives
NL6401871A (ru) * 1964-02-27 1965-08-30
GB1095378A (ru) * 1965-06-22
DE1543372A1 (de) * 1966-10-18 1971-04-01 Boehringer Sohn Ingelheim Verfahren zur Herstellung von o-substituierten 3,4-Dioxyphenylalkanolaminen

Also Published As

Publication number Publication date
NL169583B (nl) 1982-03-01
AR194205A1 (es) 1973-06-29
FI53301B (ru) 1977-12-30
ES395481A1 (es) 1973-12-16
ES386345A1 (es) 1974-01-01
YU35868B (en) 1981-08-31
PL84354B1 (ru) 1976-03-31
BE760252A (fr) 1971-06-11
RO56808A (ru) 1975-03-15
YU35867B (en) 1981-08-31
AR198224A1 (es) 1974-06-07
SE378101B (ru) 1975-08-18
JPS5138716B1 (ru) 1976-10-23
DE1962497A1 (de) 1971-06-16
FI53301C (fi) 1978-04-10
BG17956A3 (bg) 1974-03-05
RO61063A (fr) 1978-07-15
AT317192B (de) 1974-08-12
AT302284B (de) 1972-10-10
YU137878A (en) 1981-02-28
YU137978A (en) 1981-02-28
FR2081347B1 (ru) 1974-08-30
SU505349A3 (ru) 1976-02-28
NL7018031A (ru) 1971-06-15
SU384229A3 (ru) 1973-05-23
DE1962497C3 (de) 1979-09-20
DE1962497B2 (de) 1979-01-25
PL81424B1 (ru) 1975-08-30
AT299924B (de) 1972-07-10
KR780000269B1 (en) 1978-07-24
IE34807B1 (en) 1975-08-20
NL169583C (nl) 1982-08-02
NO131126C (ru) 1975-04-09
CS151062B2 (ru) 1973-09-17
CH556322A (de) 1974-11-29
RO61132A (ru) 1976-12-15
ES395482A1 (es) 1973-12-16
HU162736B (ru) 1973-04-28
JPS5221505B1 (ru) 1977-06-10
PL84355B1 (ru) 1976-03-31
CS151064B2 (ru) 1973-09-17
FR2081347A1 (ru) 1971-12-03
US3966814A (en) 1976-06-29
IE34807L (en) 1971-06-12
YU301070A (en) 1980-12-31
IL35840A0 (en) 1971-02-25
DK136526C (ru) 1978-03-28
KR780000007B1 (en) 1978-03-04
YU35753B (en) 1981-06-30
DK136526B (da) 1977-10-24
CS151063B2 (ru) 1973-09-17
GB1330188A (en) 1973-09-12
IL35840A (en) 1974-06-30
NO131126B (ru) 1974-12-30
JPS5116420B1 (ru) 1976-05-24

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