SU1277903A3 - Способ получени пептидов в виде кислотно-аддитивных солей - Google Patents

Способ получени пептидов в виде кислотно-аддитивных солей Download PDF

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Publication number
SU1277903A3
SU1277903A3 SU823454444A SU3454444A SU1277903A3 SU 1277903 A3 SU1277903 A3 SU 1277903A3 SU 823454444 A SU823454444 A SU 823454444A SU 3454444 A SU3454444 A SU 3454444A SU 1277903 A3 SU1277903 A3 SU 1277903A3
Authority
SU
USSR - Soviet Union
Prior art keywords
asp
val
lys
mmol
solution
Prior art date
Application number
SU823454444A
Other languages
English (en)
Russian (ru)
Inventor
Кишфалуди Лайош
Ньеки Олга
Шен Иштван
Денеш Ласло
Эмбер Юлиа
Хайош Дьердь
Спорни Ласло
Сенде Бела
Original Assignee
Рихтер Гедеон Ведьесети Дьяр Рт (Инопредприятие)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Application filed by Рихтер Гедеон Ведьесети Дьяр Рт (Инопредприятие) filed Critical Рихтер Гедеон Ведьесети Дьяр Рт (Инопредприятие)
Application granted granted Critical
Publication of SU1277903A3 publication Critical patent/SU1277903A3/ru
Priority to LV930047A priority Critical patent/LV5275A3/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0815—Tripeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/66—Thymopoietins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/18—Thymus derived hormone or factor; related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SU823454444A 1981-06-12 1982-06-11 Способ получени пептидов в виде кислотно-аддитивных солей SU1277903A3 (ru)

Priority Applications (1)

Application Number Priority Date Filing Date Title
LV930047A LV5275A3 (lv) 1981-06-12 1993-01-18 Peptidu iegusanas panemiens skabju aditivo saju veida

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU811755A HU185263B (en) 1981-06-12 1981-06-12 Process for producing peptides effective on the immuncontroll analogous with the tp5

Publications (1)

Publication Number Publication Date
SU1277903A3 true SU1277903A3 (ru) 1986-12-15

Family

ID=10956026

Family Applications (1)

Application Number Title Priority Date Filing Date
SU823454444A SU1277903A3 (ru) 1981-06-12 1982-06-11 Способ получени пептидов в виде кислотно-аддитивных солей

Country Status (12)

Country Link
US (1) US4428938A (enExample)
EP (1) EP0067425B1 (enExample)
JP (1) JPS5849350A (enExample)
AT (1) AT382625B (enExample)
AU (1) AU551770B2 (enExample)
BG (1) BG60738B2 (enExample)
CA (1) CA1241643A (enExample)
DE (1) DE3266354D1 (enExample)
DK (1) DK157764C (enExample)
HU (1) HU185263B (enExample)
IL (1) IL66034A (enExample)
SU (1) SU1277903A3 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989006134A1 (fr) * 1987-12-30 1989-07-13 Vsesojuzny Kardiologichesky Nauchny Tsentr Akademi Preparation pharmaceutique pour traiter des etats immunodeficitaires
WO1996026955A1 (en) * 1995-03-02 1996-09-06 Vladislav Isakovich Deigin Peptide and a method of obtaining it
US6159940A (en) * 1996-02-28 2000-12-12 Immunotech Developments Inc. Method for modulating hemopoiesis

Families Citing this family (56)

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IT1164225B (it) * 1983-05-13 1987-04-08 Anic Spa Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione
US4686282A (en) * 1983-08-12 1987-08-11 Immunetech, Inc. Immunotherapeutic polypeptide agents which block immune complex binding to immunoglobulin Fc receptors
US4579840A (en) * 1983-08-12 1986-04-01 Immunetech Pharmaceuticals Method of blocking immune complex binding to immunoglobulin Fc receptors
DE3421614A1 (de) * 1984-06-09 1985-12-12 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von pentapeptiden mit wirkung auf das immunsystem und zwischenprodukte dieses verfahrens
US4585757A (en) * 1984-07-27 1986-04-29 Texas Tech University Health Sciences Center Hypotensive active peptides
JPS61148198A (ja) * 1984-12-22 1986-07-05 Ajinomoto Co Inc 新規トリペプチド化合物および甘味剤
JPS6221465A (ja) * 1985-07-18 1987-01-29 Toyota Motor Corp アルミニウム系母材への２層肉盛方法
FR2591227B1 (fr) * 1985-12-06 1988-11-10 Pasteur Institut Peptides capables d'inhiber les interactions entre les virus lav et les lymphocytes t4, produits qui en sont derives et leurs applications
IT1188645B (it) * 1986-04-09 1988-01-20 Ellem Ind Farmaceutica Tripeptide ad attivita' immunostimolante
HUT46044A (en) * 1986-11-21 1988-09-28 Richter Gedeon Vegyeszet Process for producing immunstimulant peptides inhibiting multiplication of leukaemic cells and pharmaceutics comprising same
HU199878B (en) * 1987-06-19 1990-03-28 Berlin Chemie Veb Process for producing acylated splenopentynes and pharmaceutical compositions comprising such compounds as active ingredient
US4904802A (en) * 1987-06-30 1990-02-27 Ajinomoto Co., Inc. Imides
IT1222437B (it) * 1987-08-04 1990-09-05 Ellem Ind Farmaceutica Tripeptidi utili come immunostimolanti e nella prevenzione delle metastasi e relativo procedimento di preparazione
FR2622587B1 (fr) * 1987-10-30 1990-12-21 Inst Vaisseaux Sang Peptide lysyl-arginyl-aspartyl-serine et ses applications en tant que medicament, notamment antithrombotique
US5807830A (en) * 1987-12-30 1998-09-15 Cytoven J.V. Method for treatment of purulent inflammatory diseases
US5728680A (en) * 1987-12-30 1998-03-17 Cytoven J.V. Methods for normalizing numbers of lymphocytes
US5814611A (en) * 1988-12-14 1998-09-29 Cytoven J.V. Pharmaceutical for the therapy of immune deficiency conditions
US6136788A (en) * 1987-12-30 2000-10-24 Cytran, Inc. Pharmaceutical preparation for the therapy of immune deficiency conditions
DK15888D0 (da) * 1988-01-14 1988-01-14 Carlsberg Biotechnology Ltd Enzymatisk fremgangsmaade til fremstilling af immunmodulerende pentapeptider samt mellemprodukter til brug ved fremgangsmaaden
NZ229004A (en) * 1988-05-19 1993-09-27 Immunobiology Res Inst Inc Tetrapeptides having t cell helper acitivity
HU201095B (en) * 1988-06-14 1990-09-28 Richter Gedeon Vegyeszet New peptides inhibiting the activity of the immune system and pharmaceutical compositions comprising same, as well as process for producing these peptides and compositions
US5602100A (en) * 1988-06-30 1997-02-11 Astra Ab Dermorphin analogs having pharmacological activity
EP0350221B1 (en) * 1988-06-30 1996-04-17 Astra Aktiebolag Dermorphin analogs, their methods of preparation, pharmaceutical compositions, and methods of therapeutic treatment using the same
US5225400A (en) * 1988-07-29 1993-07-06 Ellem Industria Farmaceutica S.R.L. Immunostimulating peptides, a process for their preparation and pharmaceutical compositions containing them
US5284664A (en) * 1988-08-04 1994-02-08 Kremers-Urban Company Method of treating the symptoms of Alzheimer's disease
US5316775A (en) * 1988-08-04 1994-05-31 Kremers-Urban Company Method of treating hepatitis B infection
US5334395A (en) * 1988-08-04 1994-08-02 Kremers-Urban Company Method of treating an epstein-barr viral infection
US5055296A (en) * 1988-08-04 1991-10-08 Wagle Sudhakar S Method of treating chronic fatigue syndrome
US5013546A (en) * 1988-08-23 1991-05-07 Imreg, Inc. Methods for modulating antibody production in treating patients with AIDS, ARC and other diseases
AU627781B2 (en) * 1988-09-30 1992-09-03 Immunobiology Research Institute, Inc. Peptides having t cell suppressor activity
US5811399A (en) * 1988-12-14 1998-09-22 Cytran, Inc. Pharmaceutical dipeptide compositions and methods of use thereof: immunodepressants
US5036050A (en) * 1989-01-12 1991-07-30 Immunobiology Research Institute, Inc. Compositions containing thymopentin for topical treatment of skin disorders
HU201964B (en) * 1989-01-13 1991-01-28 Richter Gedeon Vegyeszet Process for producing peptides inhibiting maturation of t-lymphocytes and activity of macrophages, as well as pharmaceutical compositions comprising same
DD296084A5 (de) * 1989-07-27 1991-11-21 Adw Verfahren zur herstellung von humanen spleninderivaten
US5770576A (en) * 1989-08-30 1998-06-23 Cytran, Inc. Pharmaceutical dipeptide compositions and methods of use thereof: systemic toxicity
IT1237474B (it) * 1989-10-05 1993-06-07 Polifarma Spa Composti tripeptidici e loro uso farmaceutico come immuno-modulatori
HU205952B (en) * 1990-08-23 1992-07-28 Richter Gedeon Vegyeszet Process for producing cristalline h-arg-lys-asp-oh and h-arg-lys-asp-val-oh and pharmaceutically active compositions containing them
IT1244548B (it) * 1991-02-06 1994-07-15 Poli Ind Chimica Spa Derivati della 5-oxo-l-prolina e loro applicazioni farmaceutiche
US6100380A (en) * 1991-10-28 2000-08-08 Cytran, Inc. Immunomodulating peptides and methods of use
US6066622A (en) 1991-10-28 2000-05-23 Cytran, Inc. Immunomodulating peptides and methods of use
US5585359A (en) * 1994-09-29 1996-12-17 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
DE59710628D1 (de) 1996-08-12 2003-09-25 Mgb Endoskopische Geraete Gmbh Starres endoskop mit beleuchtung
US7723303B2 (en) * 2000-08-24 2010-05-25 The Regents Of The University Of California Peptides and peptide mimetics to treat pathologies characterized by an inflammatory response
US8568766B2 (en) * 2000-08-24 2013-10-29 Gattadahalli M. Anantharamaiah Peptides and peptide mimetics to treat pathologies associated with eye disease
US7199102B2 (en) * 2000-08-24 2007-04-03 The Regents Of The University Of California Orally administered peptides synergize statin activity
FI20012082A0 (fi) 2001-10-26 2001-10-26 Paeivi Liesi Biologisesti aktiiviset peptidit hermovauroiden korjaamiseksi
RU2208442C1 (ru) * 2002-04-22 2003-07-20 Восточно-Сибирский государственный технологический университет Комплексное иммунокорригирующее средство
AU2003218176A1 (en) * 2002-06-11 2003-12-22 Bristol-Myers Squibb Company Asymetric synthesis of amino-pyrrolidinones
US20060205669A1 (en) * 2004-09-16 2006-09-14 The Regents Of The University Of California G-type peptides and other agents to ameliorate atherosclerosis and other pathologies
RU2414236C2 (ru) 2004-12-06 2011-03-20 Зе Риджентс Оф Зи Юнивесити Оф Кэлифонье Способ улучшения структуры и/или функций артериол
EA200900786A1 (ru) * 2005-04-29 2009-10-30 Зе Риджентс Оф Зи Юнивесити Оф Кэлифонье Пептид в качестве лекарственного средства и способ лечения патологий, связанных с воспалительными процессами, посредством пептида
US20080293639A1 (en) * 2005-04-29 2008-11-27 The Regents Of The University Of California Peptides and peptide mimetics to treat pathologies characterized by an inflammatory response
RU2301074C1 (ru) * 2006-05-30 2007-06-20 Общество С Ограниченной Ответственностью "Сиа Пептайдс" Пептид, обладающий иммуногеропротекторным действием, фармацевтическая композиция на его основе и способ ее применения
AU2008296478B9 (en) * 2007-08-28 2015-03-19 The Uab Research Foundation Synthetic apolipoprotein E mimicking polypeptides and methods of use
JP2010537638A (ja) 2007-08-28 2010-12-09 ユーエービー リサーチ ファウンデーション 合成アポリポ蛋白質ｅ模倣ポリペプチドおよび使用方法
CA2954475C (en) 2014-07-31 2023-05-16 Uab Research Foundation Apoe mimetic peptides and higher potency to clear plasma cholesterol

Family Cites Families (5)

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US4190646A (en) 1975-11-11 1980-02-26 Sloan-Kettering Institute For Cancer Research Polypeptide compositions and methods
GB1565032A (en) * 1978-01-27 1980-04-16 Sloan Kettering Inst Cancer Polypeptide compositions and methods for their manufacture
US4261886A (en) 1980-03-13 1981-04-14 Ortho Pharmaceutical Corporation Peptides having thymopoietin-like activity
CA1157466A (en) * 1979-04-12 1983-11-22 Gideon Goldstein Peptides having thymopoietin-like activity
DE2938420A1 (de) * 1979-09-22 1981-04-09 Hoechst Ag, 6000 Frankfurt Neue peptide und verfahren zu ihrer herstellung

Non-Patent Citations (1)

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Title
Патент US № 4190646, кл. С 07 С 103/52, опублик. 1980. . *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989006134A1 (fr) * 1987-12-30 1989-07-13 Vsesojuzny Kardiologichesky Nauchny Tsentr Akademi Preparation pharmaceutique pour traiter des etats immunodeficitaires
WO1996026955A1 (en) * 1995-03-02 1996-09-06 Vladislav Isakovich Deigin Peptide and a method of obtaining it
US6051683A (en) * 1995-03-02 2000-04-18 Immunotech Developments Inc. Immune regulating peptides and method of obtaining them
US6159940A (en) * 1996-02-28 2000-12-12 Immunotech Developments Inc. Method for modulating hemopoiesis

Also Published As

Publication number Publication date
ATA227082A (de) 1986-08-15
CA1241643A (en) 1988-09-06
JPS5849350A (ja) 1983-03-23
DK157764B (da) 1990-02-12
BG60738B2 (bg) 1996-01-31
DE3266354D1 (en) 1985-10-24
HU185263B (en) 1984-12-28
AU551770B2 (en) 1986-05-08
IL66034A0 (en) 1982-09-30
EP0067425B1 (de) 1985-09-18
DK264782A (da) 1982-12-13
US4428938A (en) 1984-01-31
AU8479982A (en) 1982-12-16
JPH0357920B2 (enExample) 1991-09-03
IL66034A (en) 1985-09-29
EP0067425A1 (de) 1982-12-22
AT382625B (de) 1987-03-25
DK157764C (da) 1990-07-09

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