SU1272982A3 - Способ получени производных пролина или их фармацевтически приемлемых солей - Google Patents

Способ получени производных пролина или их фармацевтически приемлемых солей Download PDF

Info

Publication number
SU1272982A3
SU1272982A3 SU823514502A SU3514502A SU1272982A3 SU 1272982 A3 SU1272982 A3 SU 1272982A3 SU 823514502 A SU823514502 A SU 823514502A SU 3514502 A SU3514502 A SU 3514502A SU 1272982 A3 SU1272982 A3 SU 1272982A3
Authority
SU
USSR - Soviet Union
Prior art keywords
proline
compound
mixture
residue
amino acid
Prior art date
Application number
SU823514502A
Other languages
English (en)
Russian (ru)
Inventor
Танака Садао
Куромару Киенори
Фудзимура Ясуо
Мацунага Исао
Иваока Томояси
Обатаке Норико
Аоно Дзунитиро
Хинохара Есиказу
Накано Хидеки
Фукусима Масафуми
Набата Хироюки
Сакаи Казусиге
Хата Сун-Ити
Original Assignee
Чугаи Сейяку Кабусики Кайся (Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Чугаи Сейяку Кабусики Кайся (Фирма) filed Critical Чугаи Сейяку Кабусики Кайся (Фирма)
Application granted granted Critical
Publication of SU1272982A3 publication Critical patent/SU1272982A3/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01D—MEASURING NOT SPECIALLY ADAPTED FOR A SPECIFIC VARIABLE; ARRANGEMENTS FOR MEASURING TWO OR MORE VARIABLES NOT COVERED IN A SINGLE OTHER SUBCLASS; TARIFF METERING APPARATUS; MEASURING OR TESTING NOT OTHERWISE PROVIDED FOR
    • G01D2205/00—Indexing scheme relating to details of means for transferring or converting the output of a sensing member
    • G01D2205/70—Position sensors comprising a moving target with particular shapes, e.g. of soft magnetic targets
    • G01D2205/77—Specific profiles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SU823514502A 1981-06-19 1982-11-25 Способ получени производных пролина или их фармацевтически приемлемых солей SU1272982A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56094002A JPS57209270A (en) 1981-06-19 1981-06-19 Proline derivative

Publications (1)

Publication Number Publication Date
SU1272982A3 true SU1272982A3 (ru) 1986-11-23

Family

ID=14098203

Family Applications (1)

Application Number Title Priority Date Filing Date
SU823514502A SU1272982A3 (ru) 1981-06-19 1982-11-25 Способ получени производных пролина или их фармацевтически приемлемых солей

Country Status (5)

Country Link
JP (1) JPS57209270A (fr)
AT (1) AT390619B (fr)
BE (1) BE893553A (fr)
SU (1) SU1272982A3 (fr)
ZA (1) ZA823779B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2362998T3 (es) 2002-08-19 2011-07-18 Pfizer Inc. Terapia de combinación para enfermedades hiperproliferativas.
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US8404896B2 (en) 2006-12-01 2013-03-26 Bristol-Myers Squibb Company N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as CETP inhibitors for the treatment of atherosclerosis and cardiovascular diseases
AU2014255381A1 (en) 2013-04-17 2015-10-08 Pfizer Inc. N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
WO2016055901A1 (fr) 2014-10-08 2016-04-14 Pfizer Inc. Composés d'amide substitué
MX2021008533A (es) 2019-01-18 2021-08-19 Astrazeneca Ab Inhibidores de la pcsk9 y metodos de uso de los mismos.
CN115819270A (zh) * 2021-09-17 2023-03-21 洛阳中科生物芯片技术有限公司 金刚烷胺半抗原、金刚烷胺抗原、制备方法以及金刚烷胺单克隆抗体及金刚烷胺检测试剂盒

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR73585B (fr) * 1978-09-11 1984-03-26 Univ Miami
ZA802420B (en) * 1979-05-18 1981-04-29 Squibb & Sons Inc Aminoacyl derivatives of mercaptoacyl amino acids
PT70158A1 (en) * 1980-03-03 1982-03-01 Univ Miami Process for preparing anti-hypertensive agents

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Патент GB ff 2050359/ кл. С 07 D 207/16, 1981. Европейский патент № 0009898, кл..С 07 С 103/52, 1980. *

Also Published As

Publication number Publication date
JPS57209270A (en) 1982-12-22
AT390619B (de) 1990-06-11
BE893553A (fr) 1982-12-17
ZA823779B (en) 1984-01-25
JPS6313433B2 (fr) 1988-03-25
ATA238582A (de) 1989-11-15

Similar Documents

Publication Publication Date Title
US4513009A (en) Aminoacid derivatives and their therapeutic applications
EP0611375A1 (fr) Peptides inhibant la liberation d'il-1 beta
PL126126B1 (en) Process for preparing novel derivatives of dipeptides
EP0331921A1 (fr) Inhibiteurs de la rénine, contenant des alpha-hétéroatome-acides aminés
PT86366B (pt) Processo para a preparacao de derivados do acido fosfinico e de composicoes farmaceuticas que os contem
PT90659B (pt) Processo para a preparacao de inibidores de renina contendo diois
JPS6059226B2 (ja) プロリン誘導体および関連化合物
SU1272982A3 (ru) Способ получени производных пролина или их фармацевтически приемлемых солей
US3821188A (en) Proline and pyroglutamic acid containing tripeptides
US4346105A (en) Novel substituted phenylacetic acid amide compounds
US4420490A (en) Substituted phenylacetic acid amide compounds
US4250192A (en) Novel substituted phenylacetic acid amide compounds
US6403561B1 (en) Tripeptidylpeptidase inhibitors
WO1999003878A2 (fr) Nouveaux inhibiteurs des metalloproteinases, leurs emplois therapeutiques et procede de production de leur compose de depart
PL167915B1 (pl) Sposób otrzymywania nowych N-( a-podstawionych-pirydynylo)karbonylo-dipeptydów PL PL PL
US4678800A (en) Gamma-r-glutamoyl derivatives
US4665087A (en) 1-(carbamyl, thiocarbamyl, and iminocarbamyl)-indoline derivatives
FI64349C (fi) Foerfarande foer framstaellning av ett terapeutiskt anvaendbart l-pyroglutamyl-l-histidyl-glysin och dess salter
SU1316556A3 (ru) Способ получени производных пролина или их фармацевтически приемлемых солей
US4474795A (en) Enkephalinase inhibitors
RU2168493C2 (ru) Производные l-аргинина, способ их получения, фармацевтическая композиция, обладающая ингибирующей no-синтазу активностью
US4923888A (en) Butenoic acid amides, their salts, and pharmaceutical compositions containing them
SU1241988A3 (ru) Способ получени хлоргидрата (2 @ ,3 @ ,7 @ )1- @ 2- @ (1-карбэтокси-3-фенилпропил)амино/-1-оксопропил @ -октагидро-1 @ -индол-2-карбоновой кислоты в виде @ , @ , @ -или @ , @ , @ -изомеров
HAYASHI et al. Studies on angiotensin-converting enzyme inhibitors. I. Syntheses and angiotensin-converting enzyme inhibitory activity of 2-(3-mercaptopropionyl)-1, 2, 3, 4-tetrahydroisoquinoline-3-carboxylic acid derivatives
US4418205A (en) 16-Amino-18,19,20-trinor-prostaglandin derivatives, and acid addition salts