SMT202000557T1 - Derivati di benzoassazinone per il trattamento di malattie della pelle - Google Patents
Derivati di benzoassazinone per il trattamento di malattie della pelleInfo
- Publication number
- SMT202000557T1 SMT202000557T1 SM20200557T SMT202000557T SMT202000557T1 SM T202000557 T1 SMT202000557 T1 SM T202000557T1 SM 20200557 T SM20200557 T SM 20200557T SM T202000557 T SMT202000557 T SM T202000557T SM T202000557 T1 SMT202000557 T1 SM T202000557T1
- Authority
- SM
- San Marino
- Prior art keywords
- treatment
- skin diseases
- benzoxazinone derivatives
- benzoxazinone
- derivatives
- Prior art date
Links
- HQQTZCPKNZVLFF-UHFFFAOYSA-N 4h-1,2-benzoxazin-3-one Chemical class C1=CC=C2ONC(=O)CC2=C1 HQQTZCPKNZVLFF-UHFFFAOYSA-N 0.000 title 1
- 208000017520 skin disease Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/539—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines having two or more oxygen atoms in the same ring, e.g. dioxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/20—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
- C07D265/22—Oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1430003 | 2014-01-23 | ||
| PCT/SE2015/050062 WO2015112081A1 (en) | 2014-01-23 | 2015-01-22 | Benzoxazinone derivatives for treatment of skin diseases |
| EP15740572.1A EP3097085B1 (en) | 2014-01-23 | 2015-01-22 | Benzoxazinone derivatives for treatment of skin diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SMT202000557T1 true SMT202000557T1 (it) | 2020-11-10 |
Family
ID=53681747
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SM20200557T SMT202000557T1 (it) | 2014-01-23 | 2015-01-22 | Derivati di benzoassazinone per il trattamento di malattie della pelle |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US9695194B2 (enExample) |
| EP (1) | EP3097085B1 (enExample) |
| JP (1) | JP6448651B2 (enExample) |
| CN (1) | CN106132941B (enExample) |
| AU (1) | AU2015209761B2 (enExample) |
| CA (1) | CA2934025C (enExample) |
| CY (1) | CY1123477T1 (enExample) |
| DK (1) | DK3097085T3 (enExample) |
| ES (1) | ES2820868T3 (enExample) |
| HR (1) | HRP20201500T1 (enExample) |
| HU (1) | HUE051296T2 (enExample) |
| LT (1) | LT3097085T (enExample) |
| PL (1) | PL3097085T3 (enExample) |
| PT (1) | PT3097085T (enExample) |
| RS (1) | RS60830B1 (enExample) |
| SI (1) | SI3097085T1 (enExample) |
| SM (1) | SMT202000557T1 (enExample) |
| WO (1) | WO2015112081A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015112081A1 (en) * | 2014-01-23 | 2015-07-30 | Sixera Pharma Ab | Benzoxazinone derivatives for treatment of skin diseases |
| US10306885B2 (en) | 2015-05-13 | 2019-06-04 | Nihon Nohyaku Co., Ltd. | Anthranilic acid ester compound or salt thereof, agricultural and horticultural microbicide comprising the compound, and method for using the microbicide |
| EP3402572B1 (en) * | 2016-01-13 | 2022-03-16 | Children's Hospital Medical Center | Compositions and methods for treating allergic inflammatory conditions |
| KR20200021991A (ko) * | 2017-06-16 | 2020-03-02 | 아지트라 인코포레이티드 | Lekti 발현 재조합 미생물을 사용하는 네테르톤 증후군의 치료를 위한 조성물 및 방법 |
| US20200040103A1 (en) | 2018-03-14 | 2020-02-06 | Genentech, Inc. | Anti-klk5 antibodies and methods of use |
| US12360103B2 (en) | 2018-04-20 | 2025-07-15 | Children's Hospital Medical Center | Blood biomarker for eosinophilic gastrointestinal disorders |
| GB201809378D0 (en) | 2018-06-07 | 2018-07-25 | Glaxosmithkline Ip Dev Ltd | Novel compounds |
| US12297501B2 (en) | 2019-02-25 | 2025-05-13 | Children's Hospital Medical Center | Methods for diagnosing and treating eosinophilic gastritis |
| BR112022004972A2 (pt) | 2019-09-18 | 2022-06-28 | Genentech Inc | Anticorpos, ácidos nucleicos isolados, células hospedeiras isoladas, métodos de produção de um anticorpo, de produção de um anticorpo biespecífico e de tratamento de um indivíduo, anticorpos biespecíficos, composição farmacêutica, anticorpo, anticorpo biespecífico ou composição farmacêutica, combinação de um anticorpo, uso do anticorpo, uso de uma combinação do anticorpo e métodos para reduzir a inflamação e para melhorar a descamação e/ou de erupção cutânea e combinação para uso |
| JP2022551583A (ja) * | 2019-10-01 | 2022-12-12 | モレキュラー スキン セラピューティクス，インコーポレイティド | Ｋｌｋ５／７デュアル阻害剤としてのベンゾキサジノン化合物 |
| GB202001447D0 (en) * | 2020-02-03 | 2020-03-18 | Ucb Biopharma Sprl | Antibodies |
| BR102020009679A2 (pt) | 2020-05-14 | 2021-11-23 | Fundação Universidade Federal Do Abc - Ufabc | Anticorpos recombinantes humanos para inibição da calicreína tecidual humana 7 (klk7) e uso em doenças relacionadas ao processo de descamação da pele |
| TW202304890A (zh) * | 2021-04-14 | 2023-02-01 | 美商百歐克斯製藥公司 | Klk5雙環雜芳香族抑制劑 |
| EP4346761A1 (en) | 2021-06-01 | 2024-04-10 | Sixera Pharma AB | Oil-in-water emulsion of 6-ethoxy-7-methoxy-2-(2-methylsulfanylphenyl)-3,l-benzoxazin-4-one |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB115399A (en) * | 1917-03-28 | 1918-04-29 | Reginald Guley Lewis | Improved Delivery mechanism for Coin-freed Apparatus and the like. |
| GB1153994A (en) * | 1965-07-21 | 1969-06-04 | Aspro Nicholas Ltd | Hydroxyphenyl Anthranilic Acid Derivatives Capable of Absorbing 'Ultra-Violet Light and Compositions containing them |
| AU2826099A (en) | 1998-03-24 | 1999-10-18 | Novo Nordisk A/S | Heterocyclic compounds regulating clotting |
| WO2004108139A2 (en) | 2003-06-06 | 2004-12-16 | Arexis Ab | Use of fused heterocyclic compounds as scce inhibitors for the treatment of skin conditions or cancer |
| TWI419884B (zh) | 2010-06-24 | 2013-12-21 | Univ Chang Gung | 苯并雜氧嗪酮衍生物，其製備方法以及包含有此等衍生物的藥學組成物 |
| WO2015112081A1 (en) * | 2014-01-23 | 2015-07-30 | Sixera Pharma Ab | Benzoxazinone derivatives for treatment of skin diseases |
-
2015
- 2015-01-22 WO PCT/SE2015/050062 patent/WO2015112081A1/en not_active Ceased
- 2015-01-22 AU AU2015209761A patent/AU2015209761B2/en active Active
- 2015-01-22 RS RS20201128A patent/RS60830B1/sr unknown
- 2015-01-22 SM SM20200557T patent/SMT202000557T1/it unknown
- 2015-01-22 ES ES15740572T patent/ES2820868T3/es active Active
- 2015-01-22 HU HUE15740572A patent/HUE051296T2/hu unknown
- 2015-01-22 DK DK15740572.1T patent/DK3097085T3/da active
- 2015-01-22 LT LTEP15740572.1T patent/LT3097085T/lt unknown
- 2015-01-22 SI SI201531393T patent/SI3097085T1/sl unknown
- 2015-01-22 HR HRP20201500TT patent/HRP20201500T1/hr unknown
- 2015-01-22 JP JP2016544672A patent/JP6448651B2/ja active Active
- 2015-01-22 US US15/113,750 patent/US9695194B2/en active Active
- 2015-01-22 PT PT157405721T patent/PT3097085T/pt unknown
- 2015-01-22 EP EP15740572.1A patent/EP3097085B1/en active Active
- 2015-01-22 PL PL15740572T patent/PL3097085T3/pl unknown
- 2015-01-22 CN CN201580005383.4A patent/CN106132941B/zh active Active
- 2015-01-22 CA CA2934025A patent/CA2934025C/en active Active
-
2017
- 2017-06-05 US US15/614,462 patent/US10072024B2/en active Active
-
2020
- 2020-10-20 CY CY20201100988T patent/CY1123477T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HRP20201500T1 (hr) | 2020-12-25 |
| US9695194B2 (en) | 2017-07-04 |
| PL3097085T3 (pl) | 2021-01-11 |
| CA2934025A1 (en) | 2015-07-30 |
| CA2934025C (en) | 2022-06-07 |
| EP3097085A1 (en) | 2016-11-30 |
| US20170002021A1 (en) | 2017-01-05 |
| AU2015209761A1 (en) | 2016-07-07 |
| CN106132941B (zh) | 2018-04-06 |
| EP3097085A4 (en) | 2017-08-09 |
| JP2017503798A (ja) | 2017-02-02 |
| ES2820868T3 (es) | 2021-04-22 |
| EP3097085B1 (en) | 2020-07-29 |
| RS60830B1 (sr) | 2020-10-30 |
| CY1123477T1 (el) | 2022-03-24 |
| HUE051296T2 (hu) | 2021-03-01 |
| JP6448651B2 (ja) | 2019-01-09 |
| DK3097085T3 (da) | 2020-10-26 |
| US20170267692A1 (en) | 2017-09-21 |
| SI3097085T1 (sl) | 2020-11-30 |
| WO2015112081A1 (en) | 2015-07-30 |
| AU2015209761B2 (en) | 2018-11-29 |
| US10072024B2 (en) | 2018-09-11 |
| CN106132941A (zh) | 2016-11-16 |
| LT3097085T (lt) | 2020-10-12 |
| PT3097085T (pt) | 2020-10-08 |
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