HUE062134T2 - Mitokondriális betegségek kezelése - Google Patents
Mitokondriális betegségek kezeléseInfo
- Publication number
- HUE062134T2 HUE062134T2 HUE16728892A HUE16728892A HUE062134T2 HU E062134 T2 HUE062134 T2 HU E062134T2 HU E16728892 A HUE16728892 A HU E16728892A HU E16728892 A HUE16728892 A HU E16728892A HU E062134 T2 HUE062134 T2 HU E062134T2
- Authority
- HU
- Hungary
- Prior art keywords
- treatment
- mitochondrial diseases
- mitochondrial
- diseases
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
- A61K31/708—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid having oxo groups directly attached to the purine ring system, e.g. guanosine, guanylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15170825 | 2015-06-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE062134T2 true HUE062134T2 (hu) | 2023-09-28 |
Family
ID=53298228
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE16728892A HUE062134T2 (hu) | 2015-06-05 | 2016-06-03 | Mitokondriális betegségek kezelése |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US11337980B2 (hu) |
| EP (2) | EP4218938A1 (hu) |
| JP (3) | JP6885544B2 (hu) |
| CN (1) | CN107820430A (hu) |
| AU (2) | AU2016273340B2 (hu) |
| BR (1) | BR112017025839A2 (hu) |
| CA (1) | CA2991271C (hu) |
| CY (1) | CY1126058T1 (hu) |
| DK (1) | DK3302499T3 (hu) |
| ES (1) | ES2944551T3 (hu) |
| FI (1) | FI3302499T3 (hu) |
| HR (1) | HRP20230277T1 (hu) |
| HU (1) | HUE062134T2 (hu) |
| IL (2) | IL255988B (hu) |
| LT (1) | LT3302499T (hu) |
| MX (2) | MX2017015566A (hu) |
| PL (1) | PL3302499T3 (hu) |
| PT (1) | PT3302499T (hu) |
| RS (1) | RS64273B1 (hu) |
| RU (1) | RU2745611C2 (hu) |
| SI (1) | SI3302499T1 (hu) |
| WO (1) | WO2016193421A1 (hu) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2944551T3 (es) * | 2015-06-05 | 2023-06-22 | Fundacio Hospital Univ Vall Dhebron Institut De Recerca | Tratamiento de enfermedades mitocondriales |
| SI3310362T1 (sl) * | 2015-06-17 | 2020-02-28 | The Trustees Of Columbia University In The City Of New York, | Deoksinukleozidna terapija za bolezni, povzročene z neuravnoteženimi nabori nukleotidov, vključno s sindromom pomanjkanja mitohondrijske DNA |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5246708A (en) * | 1987-10-28 | 1993-09-21 | Pro-Neuron, Inc. | Methods for promoting wound healing with deoxyribonucleosides |
| ZA892928B (en) * | 1988-04-25 | 1991-01-30 | Pro Neuron Inc | Pharmaceutical compositions containing deoxyribonucleosides for wound healing |
| IT1247510B (it) | 1991-04-19 | 1994-12-17 | Univ Cagliari | Composizioni terapeutiche ad attivita' anti-hiv costituite da 2',3'-didesossiadenosina e sostanze inibitrici della adenosina-deaminasi |
| US20020006913A1 (en) * | 1997-11-04 | 2002-01-17 | Von Borstel Reid W. | Antimutagenic compositions for treatment and prevention of photodamage to skin |
| US6472378B2 (en) * | 1998-08-31 | 2002-10-29 | Pro-Neuron, Inc. | Compositions and methods for treatment of mitochondrial diseases |
| PT1171137E (pt) * | 1999-02-23 | 2008-03-17 | Univ California | Utilização de triacetiluridina para o tratamento de perturbações mitocondriais |
| EP2424495B1 (en) * | 2009-04-28 | 2018-01-17 | Bioelectron Technology Corporation | Treatment of leber's hereditary optic neuropathy and dominant optic atrophy with tocotrienol quinones |
| US20150065556A1 (en) * | 2013-08-05 | 2015-03-05 | Whitehead Institute For Biomedical Research | Therapeutic targets for mitochondrial disorders |
| CN104524546B (zh) * | 2014-12-18 | 2019-06-21 | 中国科学院广州生物医药与健康研究院 | 用于治疗Alpers-Huttenlocher综合征的药物组合物 |
| ES2944551T3 (es) * | 2015-06-05 | 2023-06-22 | Fundacio Hospital Univ Vall Dhebron Institut De Recerca | Tratamiento de enfermedades mitocondriales |
-
2016
- 2016-06-03 ES ES16728892T patent/ES2944551T3/es active Active
- 2016-06-03 FI FIEP16728892.7T patent/FI3302499T3/fi active
- 2016-06-03 MX MX2017015566A patent/MX2017015566A/es unknown
- 2016-06-03 PT PT167288927T patent/PT3302499T/pt unknown
- 2016-06-03 HU HUE16728892A patent/HUE062134T2/hu unknown
- 2016-06-03 AU AU2016273340A patent/AU2016273340B2/en active Active
- 2016-06-03 JP JP2017562304A patent/JP6885544B2/ja active Active
- 2016-06-03 EP EP23156608.4A patent/EP4218938A1/en active Pending
- 2016-06-03 HR HRP20230277TT patent/HRP20230277T1/hr unknown
- 2016-06-03 LT LTEPPCT/EP2016/062636T patent/LT3302499T/lt unknown
- 2016-06-03 SI SI201631688T patent/SI3302499T1/sl unknown
- 2016-06-03 RS RS20230259A patent/RS64273B1/sr unknown
- 2016-06-03 RU RU2018123532A patent/RU2745611C2/ru active
- 2016-06-03 PL PL16728892.7T patent/PL3302499T3/pl unknown
- 2016-06-03 US US15/578,621 patent/US11337980B2/en active Active
- 2016-06-03 CN CN201680039230.6A patent/CN107820430A/zh active Pending
- 2016-06-03 WO PCT/EP2016/062636 patent/WO2016193421A1/en active Application Filing
- 2016-06-03 CA CA2991271A patent/CA2991271C/en active Active
- 2016-06-03 DK DK16728892.7T patent/DK3302499T3/da active
- 2016-06-03 BR BR112017025839A patent/BR112017025839A2/pt not_active Application Discontinuation
- 2016-06-03 EP EP16728892.7A patent/EP3302499B1/en active Active
-
2017
- 2017-11-29 IL IL255988A patent/IL255988B/en unknown
- 2017-12-01 MX MX2022012719A patent/MX2022012719A/es unknown
-
2021
- 2021-04-28 JP JP2021075504A patent/JP2021121594A/ja active Pending
- 2021-12-08 AU AU2021282462A patent/AU2021282462B2/en active Active
-
2022
- 2022-01-10 IL IL289747A patent/IL289747A/en unknown
-
2023
- 2023-05-26 CY CY20231100251T patent/CY1126058T1/el unknown
- 2023-05-30 JP JP2023088479A patent/JP2023123444A/ja active Pending
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