DK3302499T3 - Behandling af mitokondrielle sygdomme - Google Patents
Behandling af mitokondrielle sygdomme Download PDFInfo
- Publication number
- DK3302499T3 DK3302499T3 DK16728892.7T DK16728892T DK3302499T3 DK 3302499 T3 DK3302499 T3 DK 3302499T3 DK 16728892 T DK16728892 T DK 16728892T DK 3302499 T3 DK3302499 T3 DK 3302499T3
- Authority
- DK
- Denmark
- Prior art keywords
- treatment
- mitochondrial diseases
- mitochondrial
- diseases
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
- A61K31/708—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid having oxo groups directly attached to the purine ring system, e.g. guanosine, guanylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP15170825 | 2015-06-05 | ||
PCT/EP2016/062636 WO2016193421A1 (en) | 2015-06-05 | 2016-06-03 | Treatment of mitochondrial diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3302499T3 true DK3302499T3 (da) | 2023-04-03 |
Family
ID=53298228
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK16728892.7T DK3302499T3 (da) | 2015-06-05 | 2016-06-03 | Behandling af mitokondrielle sygdomme |
Country Status (22)
Country | Link |
---|---|
US (2) | US11337980B2 (da) |
EP (2) | EP3302499B1 (da) |
JP (3) | JP6885544B2 (da) |
CN (1) | CN107820430A (da) |
AU (2) | AU2016273340B2 (da) |
BR (1) | BR112017025839A2 (da) |
CA (1) | CA2991271C (da) |
CY (1) | CY1126058T1 (da) |
DK (1) | DK3302499T3 (da) |
ES (1) | ES2944551T3 (da) |
FI (1) | FI3302499T3 (da) |
HR (1) | HRP20230277T1 (da) |
HU (1) | HUE062134T2 (da) |
IL (2) | IL255988B (da) |
LT (1) | LT3302499T (da) |
MX (2) | MX2017015566A (da) |
PL (1) | PL3302499T3 (da) |
PT (1) | PT3302499T (da) |
RS (1) | RS64273B1 (da) |
RU (1) | RU2745611C2 (da) |
SI (1) | SI3302499T1 (da) |
WO (1) | WO2016193421A1 (da) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3302499B1 (en) * | 2015-06-05 | 2023-03-15 | Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca | Treatment of mitochondrial diseases |
MX2017016425A (es) | 2015-06-17 | 2018-12-11 | Univ Columbia | Terapia con desoxinucleosidos para enfermedades generadas por grupos de nucleotidos desequilibrados, inclusive sindromes de agotamiento del adn mitocondrial. |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5246708A (en) | 1987-10-28 | 1993-09-21 | Pro-Neuron, Inc. | Methods for promoting wound healing with deoxyribonucleosides |
ZA892928B (en) * | 1988-04-25 | 1991-01-30 | Pro Neuron Inc | Pharmaceutical compositions containing deoxyribonucleosides for wound healing |
IT1247510B (it) * | 1991-04-19 | 1994-12-17 | Univ Cagliari | Composizioni terapeutiche ad attivita' anti-hiv costituite da 2',3'-didesossiadenosina e sostanze inibitrici della adenosina-deaminasi |
JPH0635389A (ja) | 1992-07-20 | 1994-02-10 | Fujitsu Ltd | ホログラム記録材料 |
US20020006913A1 (en) * | 1997-11-04 | 2002-01-17 | Von Borstel Reid W. | Antimutagenic compositions for treatment and prevention of photodamage to skin |
US6472378B2 (en) * | 1998-08-31 | 2002-10-29 | Pro-Neuron, Inc. | Compositions and methods for treatment of mitochondrial diseases |
IL144964A0 (en) * | 1999-02-23 | 2002-06-30 | Pro Neuron Inc | Methods of treatment of mitochondrial disorders |
BRPI1013376A8 (pt) * | 2009-04-28 | 2017-07-11 | Edison Pharmaceuticals Inc | Uso de quinonas de tocotrienol,preparação farmacêutica compreendendo as ditas quinonas e uso desta |
US20150065556A1 (en) * | 2013-08-05 | 2015-03-05 | Whitehead Institute For Biomedical Research | Therapeutic targets for mitochondrial disorders |
CN104524546B (zh) * | 2014-12-18 | 2019-06-21 | 中国科学院广州生物医药与健康研究院 | 用于治疗Alpers-Huttenlocher综合征的药物组合物 |
EP3302499B1 (en) * | 2015-06-05 | 2023-03-15 | Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca | Treatment of mitochondrial diseases |
-
2016
- 2016-06-03 EP EP16728892.7A patent/EP3302499B1/en active Active
- 2016-06-03 ES ES16728892T patent/ES2944551T3/es active Active
- 2016-06-03 CN CN201680039230.6A patent/CN107820430A/zh active Pending
- 2016-06-03 WO PCT/EP2016/062636 patent/WO2016193421A1/en active Application Filing
- 2016-06-03 RS RS20230259A patent/RS64273B1/sr unknown
- 2016-06-03 MX MX2017015566A patent/MX2017015566A/es unknown
- 2016-06-03 LT LTEPPCT/EP2016/062636T patent/LT3302499T/lt unknown
- 2016-06-03 JP JP2017562304A patent/JP6885544B2/ja active Active
- 2016-06-03 PL PL16728892.7T patent/PL3302499T3/pl unknown
- 2016-06-03 FI FIEP16728892.7T patent/FI3302499T3/fi active
- 2016-06-03 HU HUE16728892A patent/HUE062134T2/hu unknown
- 2016-06-03 AU AU2016273340A patent/AU2016273340B2/en active Active
- 2016-06-03 DK DK16728892.7T patent/DK3302499T3/da active
- 2016-06-03 EP EP23156608.4A patent/EP4218938A1/en active Pending
- 2016-06-03 HR HRP20230277TT patent/HRP20230277T1/hr unknown
- 2016-06-03 BR BR112017025839A patent/BR112017025839A2/pt not_active Application Discontinuation
- 2016-06-03 RU RU2018123532A patent/RU2745611C2/ru active
- 2016-06-03 US US15/578,621 patent/US11337980B2/en active Active
- 2016-06-03 CA CA2991271A patent/CA2991271C/en active Active
- 2016-06-03 PT PT167288927T patent/PT3302499T/pt unknown
- 2016-06-03 SI SI201631688T patent/SI3302499T1/sl unknown
-
2017
- 2017-11-29 IL IL255988A patent/IL255988B/en unknown
- 2017-12-01 MX MX2022012719A patent/MX2022012719A/es unknown
-
2021
- 2021-04-28 JP JP2021075504A patent/JP2021121594A/ja active Pending
- 2021-12-08 AU AU2021282462A patent/AU2021282462B2/en active Active
-
2022
- 2022-01-10 IL IL289747A patent/IL289747A/en unknown
- 2022-04-25 US US17/728,698 patent/US11998551B2/en active Active
-
2023
- 2023-05-26 CY CY20231100251T patent/CY1126058T1/el unknown
- 2023-05-30 JP JP2023088479A patent/JP2023123444A/ja active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK3134530T3 (da) | Behandling af hyperbilirubinæmi | |
DK3302565T3 (da) | Faste doseringsformer af palbociclib | |
DK3212233T3 (da) | Kombinationsterapi til behandling af sygdom | |
DK3777855T3 (da) | Fremgangsmåder til behandling af fibrotiske sygdomme | |
DK3137169T3 (da) | Hæmmere af lysin-specifik demethylase-1 | |
DK3125875T3 (da) | Inhalerbar rapamycinformulering til behandling af aldersrelaterede tilstande | |
DK3244948T3 (da) | Bestemmelse af medikamentdosis | |
DK3240612T3 (da) | Fremgangsmåder til behandling af nethindesygdomme | |
DK3390390T3 (da) | Bipyrazolylderivater egnede til behandling af autoimmunsygdomme | |
DK3169328T3 (da) | Quinolinderivater til behandling af inflammationssygdomme | |
DK3458052T3 (da) | Kombinationsbehandling af cancer | |
DK3626270T3 (da) | Behandling af kardiovaskulære sygdomme | |
DK3307267T3 (da) | Behandling af multipel sklerose | |
DK3283210T3 (da) | Fremgangsmåde | |
DK3237621T3 (da) | Varianter af human alpha-galactosidase | |
DK3548061T3 (da) | Behandling af neurologiske sygdomme | |
DK3368044T3 (da) | Behandling af hepatisk steatose-relateret oligo-ovulation | |
DK3164394T3 (da) | Gls1-inhibitorer til behandling af sygdomme | |
DK3097085T3 (da) | Benzoxazinonderivater til behandling af hudsygdomme | |
DK3297619T3 (da) | Terapeutiske anvendelser af L-4-chlorkynurenin | |
DK2897382T3 (da) | Forbedring af binaural kilde | |
DK3124621T3 (da) | Mitokondriemarkører af neurodegenerative sygdomme | |
DK3173071T3 (da) | Formularing af maropitant | |
DK3182980T3 (da) | Behandling af glykosyleringsmangelsygdomme | |
DK3200783T3 (da) | Behandling af erytromelalgi |