HUE051296T2 - Benzoxazinon-származékok bõrbetegségek kezelésére - Google Patents

Benzoxazinon-származékok bõrbetegségek kezelésére

Info

Publication number
HUE051296T2
HUE051296T2 HUE15740572A HUE15740572A HUE051296T2 HU E051296 T2 HUE051296 T2 HU E051296T2 HU E15740572 A HUE15740572 A HU E15740572A HU E15740572 A HUE15740572 A HU E15740572A HU E051296 T2 HUE051296 T2 HU E051296T2
Authority
HU
Hungary
Prior art keywords
treatment
skin diseases
benzoxazinone derivatives
benzoxazinone
derivatives
Prior art date
Application number
HUE15740572A
Other languages
English (en)
Hungarian (hu)
Inventor
Fredrik Wagberg
Goeran Leonardsson
Original Assignee
Sixera Pharma Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sixera Pharma Ab filed Critical Sixera Pharma Ab
Publication of HUE051296T2 publication Critical patent/HUE051296T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/536Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/539Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines having two or more oxygen atoms in the same ring, e.g. dioxazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/041,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/121,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/141,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/201,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
    • C07D265/22Oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HUE15740572A 2014-01-23 2015-01-22 Benzoxazinon-származékok bõrbetegségek kezelésére HUE051296T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE1430003 2014-01-23

Publications (1)

Publication Number Publication Date
HUE051296T2 true HUE051296T2 (hu) 2021-03-01

Family

ID=53681747

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE15740572A HUE051296T2 (hu) 2014-01-23 2015-01-22 Benzoxazinon-származékok bõrbetegségek kezelésére

Country Status (18)

Country Link
US (2) US9695194B2 (enExample)
EP (1) EP3097085B1 (enExample)
JP (1) JP6448651B2 (enExample)
CN (1) CN106132941B (enExample)
AU (1) AU2015209761B2 (enExample)
CA (1) CA2934025C (enExample)
CY (1) CY1123477T1 (enExample)
DK (1) DK3097085T3 (enExample)
ES (1) ES2820868T3 (enExample)
HR (1) HRP20201500T1 (enExample)
HU (1) HUE051296T2 (enExample)
LT (1) LT3097085T (enExample)
PL (1) PL3097085T3 (enExample)
PT (1) PT3097085T (enExample)
RS (1) RS60830B1 (enExample)
SI (1) SI3097085T1 (enExample)
SM (1) SMT202000557T1 (enExample)
WO (1) WO2015112081A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2934025C (en) * 2014-01-23 2022-06-07 Fredrik Wagberg Benzoxazinone derivatives for treatment of skin diseases
RU2720996C2 (ru) * 2015-05-13 2020-05-15 Нихон Нохияку Ко., Лтд. Соединение антранилата кислоты, его соль, фунгицид, включающий это соединение, и способ его применения
WO2017123401A1 (en) * 2016-01-13 2017-07-20 Children's Hospital Medical Center Compositions and methods for treating allergic inflammatory conditions
JP2020527357A (ja) 2017-06-16 2020-09-10 アジトラ インコーポレーテッド Lekti発現組換え微生物を用いたネザートン症候群の処置のための組成物および方法
US20200040103A1 (en) 2018-03-14 2020-02-06 Genentech, Inc. Anti-klk5 antibodies and methods of use
EP3781588B1 (en) 2018-04-20 2024-10-30 Children's Hospital Medical Center Blood biomarker for eosinophilic gastrointestinal disorders
GB201809378D0 (en) 2018-06-07 2018-07-25 Glaxosmithkline Ip Dev Ltd Novel compounds
US12297501B2 (en) 2019-02-25 2025-05-13 Children's Hospital Medical Center Methods for diagnosing and treating eosinophilic gastritis
US12312414B2 (en) 2019-09-18 2025-05-27 Genentech, Inc. Anti-KLK7 antibodies, anti-KLK5 antibodies, multispecific anti-KLK5/KLK7 antibodies, and methods of use
WO2021067335A1 (en) 2019-10-01 2021-04-08 Molecular Skin Therapeutics, Inc. Benzoxazinone compounds as klk5/7 dual inhibitors
GB202001447D0 (en) * 2020-02-03 2020-03-18 Ucb Biopharma Sprl Antibodies
BR102020009679A2 (pt) 2020-05-14 2021-11-23 Fundação Universidade Federal Do Abc - Ufabc Anticorpos recombinantes humanos para inibição da calicreína tecidual humana 7 (klk7) e uso em doenças relacionadas ao processo de descamação da pele
TW202304890A (zh) * 2021-04-14 2023-02-01 美商百歐克斯製藥公司 Klk5雙環雜芳香族抑制劑
US20240180915A1 (en) 2021-06-01 2024-06-06 Sixera Pharma Ab Oil-in-water emulsion of 6-ethoxy-7-methoxy-2-(2-methylsulfanylphenyl)-3,l-benzoxazin-4-one

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB115399A (en) * 1917-03-28 1918-04-29 Reginald Guley Lewis Improved Delivery mechanism for Coin-freed Apparatus and the like.
GB1153994A (en) 1965-07-21 1969-06-04 Aspro Nicholas Ltd Hydroxyphenyl Anthranilic Acid Derivatives Capable of Absorbing 'Ultra-Violet Light and Compositions containing them
WO1999048878A1 (en) * 1998-03-24 1999-09-30 Novo Nordisk A/S Heterocyclic compounds regulating clotting
PT1631295E (pt) 2003-06-06 2010-05-24 Arexis Ab Uso de compostos heterocíclicos condensados como inibidores de scce para o tratamento de doenças da pele
TWI419884B (zh) * 2010-06-24 2013-12-21 Univ Chang Gung 苯并雜氧嗪酮衍生物,其製備方法以及包含有此等衍生物的藥學組成物
CA2934025C (en) * 2014-01-23 2022-06-07 Fredrik Wagberg Benzoxazinone derivatives for treatment of skin diseases

Also Published As

Publication number Publication date
AU2015209761A1 (en) 2016-07-07
DK3097085T3 (da) 2020-10-26
US20170267692A1 (en) 2017-09-21
HRP20201500T1 (hr) 2020-12-25
RS60830B1 (sr) 2020-10-30
EP3097085B1 (en) 2020-07-29
EP3097085A4 (en) 2017-08-09
PT3097085T (pt) 2020-10-08
AU2015209761B2 (en) 2018-11-29
CA2934025C (en) 2022-06-07
ES2820868T3 (es) 2021-04-22
CN106132941B (zh) 2018-04-06
US10072024B2 (en) 2018-09-11
PL3097085T3 (pl) 2021-01-11
SMT202000557T1 (it) 2020-11-10
LT3097085T (lt) 2020-10-12
WO2015112081A1 (en) 2015-07-30
CY1123477T1 (el) 2022-03-24
JP2017503798A (ja) 2017-02-02
US9695194B2 (en) 2017-07-04
EP3097085A1 (en) 2016-11-30
CA2934025A1 (en) 2015-07-30
CN106132941A (zh) 2016-11-16
JP6448651B2 (ja) 2019-01-09
SI3097085T1 (sl) 2020-11-30
US20170002021A1 (en) 2017-01-05

Similar Documents

Publication Publication Date Title
HUE060711T2 (hu) Makrociklusos vegyületek betegségek kezelésére
HUE051296T2 (hu) Benzoxazinon-származékok bõrbetegségek kezelésére
DK3212233T3 (da) Kombinationsterapi til behandling af sygdom
IL249065A0 (en) Combination therapies for the treatment of cancer
PL3169328T3 (pl) Pochodne chinoliny do leczenia chorób zapalnych
LT3556775T (lt) Anti-lag-3 antikūnai, skirti hematologinių piktybinių susirgimų gydymui
LT3206715T (lt) Kanabidiolio naudojimas tuberozinės sklerozės komplekso gydymui
DK3240612T3 (da) Fremgangsmåder til behandling af nethindesygdomme
PL3265053T3 (pl) Sposoby leczenia skóry
HUE059694T2 (hu) Készítmény rák kezelésére
LT3390390T (lt) Bipirazolilo dariniai, tinkami naudoti autoimuninių ligų gydymui
SI3157534T1 (sl) Inhibitorji acetilholinesteraze za zdravljenje dermatoloških obolenj
EP3215219C0 (en) SKIN TREATMENT SYSTEM
IL249502B (en) New therapeutic uses of benzylideneguanidine derivatives for the treatment of diseases caused by structurally abnormal proteins
HUE060517T2 (hu) Immunhiányos betegség kezelésére szolgáló eljárások
HUE053443T2 (hu) Heteroaril vegyületek szembetegségek kezelésére
LT3119384T (lt) Intrahepatinių cholestazinių ligų gydymas
HUE053648T2 (hu) Gyógyászati kombinációk rák kezelésére
KR20180084983A (ko) 암의 치료를 위한 피리미도-피리미다지논의 용도
HUE070257T2 (hu) Vegyületek a lipofuscinhoz kapcsolódó betegségek kezelésére
IL259381B (en) Mirabegron for the treatment of retinal diseases
PL3302499T3 (pl) Leczenie chorób mitochondrialnych
HUE063820T2 (hu) Módszerek kardiovaszkuláris betegségek kezelésére
DK3182980T3 (da) Behandling af glykosyleringsmangelsygdomme
IL263076B (en) Treatment of skin lesions