SMT202000415T1 - Composto pirazolina-derivato e suo uso in un regime di dosaggio settimanale contro l'infiammazione e il dolore derivati dalla malattia degenerativa delle articolazioni nei mammiferi - Google Patents
Composto pirazolina-derivato e suo uso in un regime di dosaggio settimanale contro l'infiammazione e il dolore derivati dalla malattia degenerativa delle articolazioni nei mammiferiInfo
- Publication number
- SMT202000415T1 SMT202000415T1 SM20200415T SMT202000415T SMT202000415T1 SM T202000415 T1 SMT202000415 T1 SM T202000415T1 SM 20200415 T SM20200415 T SM 20200415T SM T202000415 T SMT202000415 T SM T202000415T SM T202000415 T1 SMT202000415 T1 SM T202000415T1
- Authority
- SM
- San Marino
- Prior art keywords
- derived
- pyrazoline
- mammals
- dosage regimen
- joint disease
- Prior art date
Links
- 206010061218 Inflammation Diseases 0.000 title 1
- 241000124008 Mammalia Species 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 230000004054 inflammatory process Effects 0.000 title 1
- 201000008482 osteoarthritis Diseases 0.000 title 1
- DNXIASIHZYFFRO-UHFFFAOYSA-N pyrazoline Chemical compound C1CN=NC1 DNXIASIHZYFFRO-UHFFFAOYSA-N 0.000 title 1
- 230000003442 weekly effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14382396.1A EP3009137A1 (en) | 2014-10-16 | 2014-10-16 | Pyrazoline-derived compound and its use in a weekly dosage regime against inflammation and pain derived from degenerative joint disease in mammals |
| EP15778958.7A EP3206684B1 (en) | 2014-10-16 | 2015-10-13 | Pyrazoline-derived compound and its use in a weekly dosage regimen against inflammation and pain derived from degenerative joint disease in mammals |
| PCT/EP2015/073635 WO2016059028A1 (en) | 2014-10-16 | 2015-10-13 | Pyrazoline-derived compound and its use in a weekly dosage regime against inflammation and pain derived from degenerative joint disease in mammals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SMT202000415T1 true SMT202000415T1 (it) | 2020-11-10 |
Family
ID=51844648
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SM20200415T SMT202000415T1 (it) | 2014-10-16 | 2015-10-13 | Composto pirazolina-derivato e suo uso in un regime di dosaggio settimanale contro l'infiammazione e il dolore derivati dalla malattia degenerativa delle articolazioni nei mammiferi |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US11154536B2 (enExample) |
| EP (2) | EP3009137A1 (enExample) |
| JP (1) | JP6655625B2 (enExample) |
| CN (2) | CN115154465A (enExample) |
| AR (1) | AR102295A1 (enExample) |
| CA (1) | CA2964428C (enExample) |
| CY (1) | CY1123243T1 (enExample) |
| DK (1) | DK3206684T3 (enExample) |
| ES (1) | ES2828435T3 (enExample) |
| HR (1) | HRP20201233T1 (enExample) |
| HU (1) | HUE050511T2 (enExample) |
| LT (1) | LT3206684T (enExample) |
| MX (1) | MX376725B (enExample) |
| PL (1) | PL3206684T3 (enExample) |
| PT (1) | PT3206684T (enExample) |
| RS (1) | RS60777B1 (enExample) |
| SI (1) | SI3206684T1 (enExample) |
| SM (1) | SMT202000415T1 (enExample) |
| TW (1) | TWI707678B (enExample) |
| WO (1) | WO2016059028A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109303784B (zh) * | 2018-09-30 | 2020-06-23 | 山东省文登整骨医院 | 痛风性关节炎动物模型的构建方法 |
| TWI875757B (zh) * | 2019-05-08 | 2025-03-11 | 瑞士商諾華公司 | T1dm和胰島炎治療中使用之抗cd40抗體 |
| EP4029502A1 (en) | 2021-01-15 | 2022-07-20 | Ecuphar N.V. | Pyrazoline-derived compound (enflicoxib) for use in the prevention and/or treatment of pain and inflammation associated to surgery in mammals |
| US12208085B2 (en) | 2022-05-31 | 2025-01-28 | Ecuphar Nv | Pyrazoline-derived compound for use in the prevention and/or treatment of pain and inflammation associated to surgery in mammals |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU773615B2 (en) * | 1997-05-05 | 2004-05-27 | Pfizer Inc. | COX-2 selective carprofen for treating pain and inflammation in dogs |
| ES2137138B1 (es) | 1998-05-29 | 2000-09-16 | Esteve Labor Dr | Derivados de pirazolinas, su preparacion y su aplicacion como medicamentos. |
| US20050131028A1 (en) * | 2003-09-11 | 2005-06-16 | Pharmacia Corporation | Methods and compositions for the extended duration treatment of pain, inflammation and inflammation-related disorders |
| CN101175769A (zh) * | 2005-03-10 | 2008-05-07 | 健泰科生物技术公司 | 用于调控血管完整性的方法和组合物 |
-
2014
- 2014-10-16 EP EP14382396.1A patent/EP3009137A1/en not_active Withdrawn
-
2015
- 2015-10-13 ES ES15778958T patent/ES2828435T3/es active Active
- 2015-10-13 CN CN202210698831.5A patent/CN115154465A/zh active Pending
- 2015-10-13 SM SM20200415T patent/SMT202000415T1/it unknown
- 2015-10-13 DK DK15778958.7T patent/DK3206684T3/da active
- 2015-10-13 CN CN201580068592.3A patent/CN107257684A/zh active Pending
- 2015-10-13 PT PT157789587T patent/PT3206684T/pt unknown
- 2015-10-13 RS RS20200943A patent/RS60777B1/sr unknown
- 2015-10-13 MX MX2017004899A patent/MX376725B/es active IP Right Grant
- 2015-10-13 US US15/518,871 patent/US11154536B2/en active Active
- 2015-10-13 PL PL15778958T patent/PL3206684T3/pl unknown
- 2015-10-13 SI SI201531302T patent/SI3206684T1/sl unknown
- 2015-10-13 HR HRP20201233TT patent/HRP20201233T1/hr unknown
- 2015-10-13 WO PCT/EP2015/073635 patent/WO2016059028A1/en not_active Ceased
- 2015-10-13 EP EP15778958.7A patent/EP3206684B1/en active Active
- 2015-10-13 CA CA2964428A patent/CA2964428C/en active Active
- 2015-10-13 HU HUE15778958A patent/HUE050511T2/hu unknown
- 2015-10-13 LT LTEP15778958.7T patent/LT3206684T/lt unknown
- 2015-10-13 JP JP2017539508A patent/JP6655625B2/ja active Active
- 2015-10-16 AR ARP150103353A patent/AR102295A1/es not_active Application Discontinuation
- 2015-10-16 TW TW104134072A patent/TWI707678B/zh active
-
2020
- 2020-08-03 CY CY20201100714T patent/CY1123243T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK3206684T3 (da) | 2020-08-10 |
| HRP20201233T1 (hr) | 2020-11-13 |
| CN115154465A (zh) | 2022-10-11 |
| MX376725B (es) | 2025-03-07 |
| TWI707678B (zh) | 2020-10-21 |
| PL3206684T3 (pl) | 2021-01-11 |
| WO2016059028A1 (en) | 2016-04-21 |
| EP3206684A1 (en) | 2017-08-23 |
| AR102295A1 (es) | 2017-02-15 |
| HUE050511T2 (hu) | 2020-12-28 |
| ES2828435T3 (es) | 2021-05-26 |
| CY1123243T1 (el) | 2021-10-29 |
| JP6655625B2 (ja) | 2020-02-26 |
| CN107257684A (zh) | 2017-10-17 |
| PT3206684T (pt) | 2020-08-24 |
| EP3009137A1 (en) | 2016-04-20 |
| TW201625239A (zh) | 2016-07-16 |
| CA2964428A1 (en) | 2016-04-21 |
| JP2017531042A (ja) | 2017-10-19 |
| LT3206684T (lt) | 2020-10-12 |
| CA2964428C (en) | 2022-01-04 |
| SI3206684T1 (sl) | 2020-11-30 |
| US20170231961A1 (en) | 2017-08-17 |
| US11154536B2 (en) | 2021-10-26 |
| EP3206684B1 (en) | 2020-06-17 |
| RS60777B1 (sr) | 2020-10-30 |
| MX2017004899A (es) | 2018-02-12 |
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