SMT201900375T1 - Intermedi sintetici per la preparazione di coniugati di oligosaccaride-proteina - Google Patents

Intermedi sintetici per la preparazione di coniugati di oligosaccaride-proteina

Info

Publication number
SMT201900375T1
SMT201900375T1 SM20190375T SMT201900375T SMT201900375T1 SM T201900375 T1 SMT201900375 T1 SM T201900375T1 SM 20190375 T SM20190375 T SM 20190375T SM T201900375 T SMT201900375 T SM T201900375T SM T201900375 T1 SMT201900375 T1 SM T201900375T1
Authority
SM
San Marino
Prior art keywords
protein conjugates
synthetic intermediates
preparing oligosaccharide
oligosaccharide
preparing
Prior art date
Application number
SM20190375T
Other languages
English (en)
Italian (it)
Inventor
Clark Q Pan
Xiaoyang Zheng
Robert J Miller
Joseph P Kutzko
Yunxiang Zhu
Duncan E Patterson
Andreas Peer
Paul A Konowick
Luis Z Avila
James E Stefano
Michael R Reardon
John Harrahy
Qun Zhou
Lauren Young
Patrick Finn
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of SMT201900375T1 publication Critical patent/SMT201900375T1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
SM20190375T 2008-12-16 2009-12-11 Intermedi sintetici per la preparazione di coniugati di oligosaccaride-proteina SMT201900375T1 (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12285108P 2008-12-16 2008-12-16
EP14194176.5A EP2889043B1 (en) 2008-12-16 2009-12-11 Synthetic intermediates for preparing oligosaccharide-protein conjugates

Publications (1)

Publication Number Publication Date
SMT201900375T1 true SMT201900375T1 (it) 2019-09-09

Family

ID=42138937

Family Applications (2)

Application Number Title Priority Date Filing Date
SM20190375T SMT201900375T1 (it) 2008-12-16 2009-12-11 Intermedi sintetici per la preparazione di coniugati di oligosaccaride-proteina
SM201500082T SMT201500082B (it) 2008-12-16 2015-03-30 Coniugati di oligosaccaride-proteina

Family Applications After (1)

Application Number Title Priority Date Filing Date
SM201500082T SMT201500082B (it) 2008-12-16 2015-03-30 Coniugati di oligosaccaride-proteina

Country Status (20)

Country Link
US (5) US8835614B2 (OSRAM)
EP (5) EP4212541A1 (OSRAM)
JP (6) JP5658167B2 (OSRAM)
CN (5) CN112220930A (OSRAM)
BR (2) BRPI0923047B8 (OSRAM)
CA (2) CA3040973A1 (OSRAM)
CY (1) CY1121860T1 (OSRAM)
DK (3) DK3608330T3 (OSRAM)
ES (3) ES2534056T3 (OSRAM)
HR (2) HRP20150340T1 (OSRAM)
HU (2) HUE060974T2 (OSRAM)
IL (5) IL213595B (OSRAM)
LT (1) LT2889043T (OSRAM)
MX (3) MX364498B (OSRAM)
PL (2) PL2889043T3 (OSRAM)
PT (2) PT2465542E (OSRAM)
SI (2) SI2889043T1 (OSRAM)
SM (2) SMT201900375T1 (OSRAM)
TR (1) TR201909909T4 (OSRAM)
WO (1) WO2010075010A2 (OSRAM)

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