SMT201600083B - Nuove forme e sali di un inibitore di diidropirrolo[1,2-c]imidazolil aldosterone sintasi o aromatasi - Google Patents

Nuove forme e sali di un inibitore di diidropirrolo[1,2-c]imidazolil aldosterone sintasi o aromatasi

Info

Publication number
SMT201600083B
SMT201600083B SM201600083T SM201600083T SMT201600083B SM T201600083 B SMT201600083 B SM T201600083B SM 201600083 T SM201600083 T SM 201600083T SM 201600083 T SM201600083 T SM 201600083T SM T201600083 B SMT201600083 B SM T201600083B
Authority
SM
San Marino
Prior art keywords
synthasis
diidropirrol
aromatasis
aldosterone
imidazolyl
Prior art date
Application number
SM201600083T
Other languages
English (en)
Italian (it)
Inventor
Paul Sutton
Eric Loeser
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47604250&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SMT201600083(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SMT201600083B publication Critical patent/SMT201600083B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/46—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of glucocorticosteroids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SM201600083T 2012-01-17 2016-03-23 Nuove forme e sali di un inibitore di diidropirrolo[1,2-c]imidazolil aldosterone sintasi o aromatasi SMT201600083B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261587280P 2012-01-17 2012-01-17
PCT/US2013/021521 WO2013109514A1 (en) 2012-01-17 2013-01-15 New forms and salts of a dihydropyrrolo[1,2-c]imidazolyl aldosterone synthase or aromatase inhibitor

Publications (1)

Publication Number Publication Date
SMT201600083B true SMT201600083B (it) 2016-04-29

Family

ID=47604250

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201600083T SMT201600083B (it) 2012-01-17 2016-03-23 Nuove forme e sali di un inibitore di diidropirrolo[1,2-c]imidazolil aldosterone sintasi o aromatasi

Country Status (41)

Country Link
US (2) US9334276B2 (zh)
EP (1) EP2804863B1 (zh)
JP (1) JP5749410B2 (zh)
KR (2) KR20140141687A (zh)
CN (1) CN104039793B (zh)
AP (1) AP2014007762A0 (zh)
AR (1) AR089728A1 (zh)
AU (1) AU2013209952B2 (zh)
BR (1) BR112014017260A8 (zh)
CA (1) CA2863339C (zh)
CL (1) CL2014001863A1 (zh)
CO (1) CO7000775A2 (zh)
CR (1) CR20140345A (zh)
CU (1) CU20140086A7 (zh)
CY (1) CY1117914T1 (zh)
DK (1) DK2804863T3 (zh)
EA (1) EA026232B1 (zh)
ES (1) ES2564143T3 (zh)
GT (1) GT201400155A (zh)
HK (1) HK1198536A1 (zh)
HR (1) HRP20160178T1 (zh)
HU (1) HUE026984T2 (zh)
IL (1) IL233541B (zh)
IN (1) IN2014DN06781A (zh)
JO (1) JO3137B1 (zh)
MA (1) MA35858B1 (zh)
MX (1) MX2014008686A (zh)
NZ (1) NZ626277A (zh)
PE (1) PE20142358A1 (zh)
PH (1) PH12014501638A1 (zh)
PL (1) PL2804863T3 (zh)
RS (1) RS54589B1 (zh)
SG (1) SG11201404061YA (zh)
SI (1) SI2804863T1 (zh)
SM (1) SMT201600083B (zh)
TN (1) TN2014000256A1 (zh)
TW (1) TWI609869B (zh)
UA (1) UA114803C2 (zh)
UY (1) UY34576A (zh)
WO (1) WO2013109514A1 (zh)
ZA (1) ZA201404314B (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2598708C2 (ru) * 2010-01-14 2016-09-27 Новартис Аг Применение агента, обладающего модифицирующими свойствами в отношении гормонов надпочечников
EP2815749A1 (en) 2013-06-20 2014-12-24 IP Gesellschaft für Management mbH Solid form of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione having specified X-ray diffraction pattern
PT3166596T (pt) 2014-07-07 2018-10-19 Novartis Ag Formas farmacêuticas
BR112017014706A2 (pt) * 2015-01-29 2018-02-06 Novartis Ag processo para a produção de derivados de imidazol condensado
WO2016164476A2 (en) * 2015-04-06 2016-10-13 Millendo Therapeutics, Inc. Combination therapy for treating disorders associated with excess cortisol production
CN114853755A (zh) * 2016-10-27 2022-08-05 达米安制药股份公司 醛固酮合酶抑制剂
WO2018078049A1 (en) * 2016-10-27 2018-05-03 Damian Pharma Ag Aldosterone synthase inhibitor
WO2019211394A1 (en) 2018-05-03 2019-11-07 Damian Pharma Ag R-fadrozole for use in the treatment of aldostonerism

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1315449A (en) * 1918-11-15 1919-09-09 Frank B Yingling Shaper-feed.
US4617307A (en) * 1984-06-20 1986-10-14 Ciba-Geigy Corporation Substituted imidazo[1,5-A]pyridine derivatives as aromatase inhibitors
US5066656A (en) 1989-11-01 1991-11-19 Janssen Pharmaceutica N.V. Pharmacologically active (6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl)- and (5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl) substituted 1H-benzotriazole derivatives
MTP1076B (en) * 1990-01-12 1991-09-30 Ciba Geigy Ag Hemihydrate
CA2127689A1 (en) 1992-01-27 1993-08-05 Marcel A. C. Janssen Pyrroloimidazolyl and imidazopyridinyl substituted 1h-benzimidazole derivatives as aromatase inhibitors
ATE398124T1 (de) 2002-11-18 2008-07-15 Novartis Pharma Gmbh Imidazoä1,5üa pyridin-derivate und methoden zur behandlung von krankheiten in verbindung mit aldosteron
GT200600381A (es) * 2005-08-25 2007-03-28 Compuestos organicos
US20100041722A1 (en) 2006-12-18 2010-02-18 Qi-Ying Hu Organic compounds
WO2011064376A1 (en) 2009-11-30 2011-06-03 Novartis Ag Imidazole derivatives as aldosterone synthase inhibitors
RU2598708C2 (ru) * 2010-01-14 2016-09-27 Новартис Аг Применение агента, обладающего модифицирующими свойствами в отношении гормонов надпочечников

Also Published As

Publication number Publication date
CA2863339A1 (en) 2013-07-25
DK2804863T3 (en) 2016-03-07
JO3137B1 (ar) 2017-09-20
PH12014501638B1 (en) 2014-10-13
UA114803C2 (uk) 2017-08-10
SI2804863T1 (sl) 2016-05-31
CN104039793A (zh) 2014-09-10
EA026232B1 (ru) 2017-03-31
MA35858B1 (fr) 2014-12-01
RS54589B1 (en) 2016-08-31
US20140364470A1 (en) 2014-12-11
TN2014000256A1 (en) 2015-09-30
BR112014017260A8 (pt) 2017-07-04
EA201491374A1 (ru) 2014-12-30
WO2013109514A1 (en) 2013-07-25
CR20140345A (es) 2014-09-09
PH12014501638A1 (en) 2014-10-13
PE20142358A1 (es) 2015-01-30
AU2013209952B2 (en) 2016-09-01
CA2863339C (en) 2021-03-23
KR20140093726A (ko) 2014-07-28
TWI609869B (zh) 2018-01-01
CU20140086A7 (es) 2014-12-26
CL2014001863A1 (es) 2014-11-07
UY34576A (es) 2013-09-02
NZ626277A (en) 2015-10-30
CO7000775A2 (es) 2014-07-21
PL2804863T3 (pl) 2016-06-30
AR089728A1 (es) 2014-09-10
SG11201404061YA (en) 2014-08-28
IL233541A0 (en) 2014-08-31
IN2014DN06781A (zh) 2015-05-22
JP2015503627A (ja) 2015-02-02
ES2564143T3 (es) 2016-03-18
IL233541B (en) 2018-12-31
HUE026984T2 (en) 2016-08-29
US20160176883A1 (en) 2016-06-23
CY1117914T1 (el) 2017-05-17
TW201335161A (zh) 2013-09-01
GT201400155A (es) 2017-09-28
AP2014007762A0 (en) 2014-07-31
JP5749410B2 (ja) 2015-07-15
KR20140141687A (ko) 2014-12-10
US9334276B2 (en) 2016-05-10
HRP20160178T1 (hr) 2016-03-25
EP2804863B1 (en) 2015-12-02
EP2804863A1 (en) 2014-11-26
CN104039793B (zh) 2017-05-10
MX2014008686A (es) 2014-08-27
HK1198536A1 (zh) 2015-05-15
AU2013209952A1 (en) 2014-07-24
BR112014017260A2 (pt) 2017-06-13
ZA201404314B (en) 2015-08-26
ES2564143T8 (es) 2020-11-18

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