SMT201500230B - Separatzione de enantiomeri di derivati di triazina usando acido tartarico - Google Patents

Separatzione de enantiomeri di derivati di triazina usando acido tartarico

Info

Publication number
SMT201500230B
SMT201500230B SM201500230T SM201500230T SMT201500230B SM T201500230 B SMT201500230 B SM T201500230B SM 201500230 T SM201500230 T SM 201500230T SM 201500230 T SM201500230 T SM 201500230T SM T201500230 B SMT201500230 B SM T201500230B
Authority
SM
San Marino
Prior art keywords
enantiomers
separation
tartaric acid
triazine derivatives
triazine
Prior art date
Application number
SM201500230T
Other languages
English (en)
Inventor
Daniel Cravo
Matthias Helmreich
Original Assignee
Poxel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poxel filed Critical Poxel
Publication of SMT201500230B publication Critical patent/SMT201500230B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D251/00Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/10Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00Separation of optically-active compounds
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/582Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SM201500230T 2010-12-01 2015-09-25 Separatzione de enantiomeri di derivati di triazina usando acido tartarico SMT201500230B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10306327 2010-12-01
PCT/EP2011/071347 WO2012072663A1 (en) 2010-12-01 2011-11-30 Separation of triazine derivatives enantiomers using tartaric acid

Publications (1)

Publication Number Publication Date
SMT201500230B true SMT201500230B (it) 2015-10-30

Family

ID=45047827

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201500230T SMT201500230B (it) 2010-12-01 2015-09-25 Separatzione de enantiomeri di derivati di triazina usando acido tartarico

Country Status (24)

Country Link
US (1) US8742103B2 (it)
EP (1) EP2646422B1 (it)
JP (1) JP5758010B2 (it)
KR (1) KR101530924B1 (it)
CN (1) CN103228635B (it)
AU (1) AU2011334992B2 (it)
BR (1) BR112013010115B1 (it)
CA (1) CA2816357C (it)
CY (1) CY1117407T1 (it)
DK (1) DK2646422T3 (it)
EA (1) EA022300B1 (it)
ES (1) ES2548038T3 (it)
HR (1) HRP20151022T1 (it)
HU (1) HUE026090T2 (it)
IL (1) IL226053A (it)
ME (1) ME02208B (it)
MX (1) MX345822B (it)
PL (1) PL2646422T3 (it)
PT (1) PT2646422E (it)
RS (1) RS54397B1 (it)
SI (1) SI2646422T1 (it)
SM (1) SMT201500230B (it)
TW (1) TWI428311B (it)
WO (1) WO2012072663A1 (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2020003243A (es) 2017-10-02 2020-09-18 Poxel Métodos para tratar la insuficiencia cardíaca con fracción de eyección preservada.
WO2019236844A1 (en) 2018-06-06 2019-12-12 Metavant Sciences Gmbh Methods of treating subjects having diabetes with chronic kidney disease
CN112218623A (zh) 2018-06-14 2021-01-12 博希尔公司 用于治疗糖尿病的包含三嗪衍生物的薄膜包衣片剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2804113B1 (fr) * 2000-01-26 2004-06-18 Lipha Derives animes de dihydro-1,3,5-triazine et leurs applications en therapeutique
FR2853650B1 (fr) 2003-04-10 2006-07-07 Merck Sante Sas Procede de dedoublement d'amines utiles pour le traitement de desordres associes au syndrome d'insulino-resistance
US7458318B2 (en) 2006-02-01 2008-12-02 Speedline Technologies, Inc. Off-axis illumination assembly and method
DE102008007314A1 (de) 2008-02-02 2009-08-06 Merck Patent Gmbh Verfahren zur Herstellung von 3,6-Dihydro-1,3,5-triazinderivaten
RS54736B1 (sr) 2008-05-23 2016-10-31 Poxel Sas Postupak za sintezu derivata 3,6-dihidro-1,3,5-triazina

Also Published As

Publication number Publication date
KR20130093160A (ko) 2013-08-21
AU2011334992A1 (en) 2013-05-30
HRP20151022T1 (hr) 2015-12-18
TW201228999A (en) 2012-07-16
AU2011334992B2 (en) 2016-03-24
IL226053A0 (en) 2013-06-27
US20130261300A1 (en) 2013-10-03
PL2646422T3 (pl) 2015-12-31
IL226053A (en) 2015-03-31
US8742103B2 (en) 2014-06-03
WO2012072663A9 (en) 2012-08-30
TWI428311B (zh) 2014-03-01
RS54397B1 (en) 2016-04-28
CA2816357A1 (en) 2012-06-07
EA022300B1 (ru) 2015-12-30
EA201300650A1 (ru) 2013-11-29
CN103228635B (zh) 2016-03-30
DK2646422T3 (en) 2015-10-05
KR101530924B1 (ko) 2015-06-23
JP5758010B2 (ja) 2015-08-05
MX2013006017A (es) 2013-07-15
MX345822B (es) 2017-02-17
BR112013010115A2 (pt) 2016-07-05
EP2646422B1 (en) 2015-07-08
PT2646422E (pt) 2015-10-20
ES2548038T3 (es) 2015-10-13
EP2646422A1 (en) 2013-10-09
SI2646422T1 (sl) 2016-02-29
ME02208B (me) 2016-02-20
CA2816357C (en) 2015-04-28
BR112013010115B1 (pt) 2018-12-04
WO2012072663A1 (en) 2012-06-07
CY1117407T1 (el) 2017-04-26
HUE026090T2 (en) 2016-05-30
CN103228635A (zh) 2013-07-31
JP2014504281A (ja) 2014-02-20

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