BR112013010115A2 - separação de enantiômeros derivados de triazina utilizando ácido tartárico - Google Patents

separação de enantiômeros derivados de triazina utilizando ácido tartárico

Info

Publication number
BR112013010115A2
BR112013010115A2 BR112013010115A BR112013010115A BR112013010115A2 BR 112013010115 A2 BR112013010115 A2 BR 112013010115A2 BR 112013010115 A BR112013010115 A BR 112013010115A BR 112013010115 A BR112013010115 A BR 112013010115A BR 112013010115 A2 BR112013010115 A2 BR 112013010115A2
Authority
BR
Brazil
Prior art keywords
enantiomers
triazine
derived
separation
tartaric acid
Prior art date
Application number
BR112013010115A
Other languages
English (en)
Other versions
BR112013010115B1 (pt
Inventor
Daniel Cravo
Matthias Helmreich
Original Assignee
Poxel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poxel filed Critical Poxel
Publication of BR112013010115A2 publication Critical patent/BR112013010115A2/pt
Publication of BR112013010115B1 publication Critical patent/BR112013010115B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D251/00Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/10Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00Separation of optically-active compounds
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/582Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BR112013010115-6A 2010-12-01 2011-11-30 processo de separação de enantiômeros derivados de triazina utilizando ácido tartárico BR112013010115B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10306327.7 2010-12-01
EP10306327 2010-12-01
PCT/EP2011/071347 WO2012072663A1 (en) 2010-12-01 2011-11-30 Separation of triazine derivatives enantiomers using tartaric acid

Publications (2)

Publication Number Publication Date
BR112013010115A2 true BR112013010115A2 (pt) 2016-07-05
BR112013010115B1 BR112013010115B1 (pt) 2018-12-04

Family

ID=45047827

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013010115-6A BR112013010115B1 (pt) 2010-12-01 2011-11-30 processo de separação de enantiômeros derivados de triazina utilizando ácido tartárico

Country Status (24)

Country Link
US (1) US8742103B2 (pt)
EP (1) EP2646422B1 (pt)
JP (1) JP5758010B2 (pt)
KR (1) KR101530924B1 (pt)
CN (1) CN103228635B (pt)
AU (1) AU2011334992B2 (pt)
BR (1) BR112013010115B1 (pt)
CA (1) CA2816357C (pt)
CY (1) CY1117407T1 (pt)
DK (1) DK2646422T3 (pt)
EA (1) EA022300B1 (pt)
ES (1) ES2548038T3 (pt)
HR (1) HRP20151022T1 (pt)
HU (1) HUE026090T2 (pt)
IL (1) IL226053A (pt)
ME (1) ME02208B (pt)
MX (1) MX345822B (pt)
PL (1) PL2646422T3 (pt)
PT (1) PT2646422E (pt)
RS (1) RS54397B1 (pt)
SI (1) SI2646422T1 (pt)
SM (1) SMT201500230B (pt)
TW (1) TWI428311B (pt)
WO (1) WO2012072663A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200102982A (ko) 2017-10-02 2020-09-01 폭셀 보존된 박출률을 갖는 심부전의 치료 방법
TW202015696A (zh) 2018-06-06 2020-05-01 瑞士商梅萬特科學公司 治療患有慢性腎臟病之糖尿病患者之方法
JP7266616B2 (ja) 2018-06-14 2023-04-28 ポクセル 糖尿病の治療において使用するためのトリアジン誘導体を含むフィルムコーティング錠剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2804113B1 (fr) * 2000-01-26 2004-06-18 Lipha Derives animes de dihydro-1,3,5-triazine et leurs applications en therapeutique
FR2853650B1 (fr) * 2003-04-10 2006-07-07 Merck Sante Sas Procede de dedoublement d'amines utiles pour le traitement de desordres associes au syndrome d'insulino-resistance
US7458318B2 (en) 2006-02-01 2008-12-02 Speedline Technologies, Inc. Off-axis illumination assembly and method
DE102008007314A1 (de) 2008-02-02 2009-08-06 Merck Patent Gmbh Verfahren zur Herstellung von 3,6-Dihydro-1,3,5-triazinderivaten
PL2300444T3 (pl) 2008-05-23 2016-08-31 Poxel Sas Sposób syntezy pochodnych 3,6-dihydro-1,3,5-triazyny

Also Published As

Publication number Publication date
CN103228635A (zh) 2013-07-31
WO2012072663A1 (en) 2012-06-07
PL2646422T3 (pl) 2015-12-31
EA201300650A1 (ru) 2013-11-29
KR101530924B1 (ko) 2015-06-23
ES2548038T3 (es) 2015-10-13
WO2012072663A9 (en) 2012-08-30
SI2646422T1 (sl) 2016-02-29
EP2646422A1 (en) 2013-10-09
CA2816357A1 (en) 2012-06-07
JP5758010B2 (ja) 2015-08-05
JP2014504281A (ja) 2014-02-20
IL226053A0 (en) 2013-06-27
DK2646422T3 (en) 2015-10-05
SMT201500230B (it) 2015-10-30
PT2646422E (pt) 2015-10-20
AU2011334992A1 (en) 2013-05-30
AU2011334992B2 (en) 2016-03-24
EA022300B1 (ru) 2015-12-30
TW201228999A (en) 2012-07-16
RS54397B1 (en) 2016-04-28
IL226053A (en) 2015-03-31
HUE026090T2 (en) 2016-05-30
CN103228635B (zh) 2016-03-30
KR20130093160A (ko) 2013-08-21
MX2013006017A (es) 2013-07-15
CY1117407T1 (el) 2017-04-26
CA2816357C (en) 2015-04-28
ME02208B (me) 2016-02-20
EP2646422B1 (en) 2015-07-08
US20130261300A1 (en) 2013-10-03
TWI428311B (zh) 2014-03-01
HRP20151022T1 (hr) 2015-12-18
BR112013010115B1 (pt) 2018-12-04
MX345822B (es) 2017-02-17
US8742103B2 (en) 2014-06-03

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 30/11/2011, OBSERVADAS AS CONDICOES LEGAIS.

B16D Grant of patent or certificate of addition of invention cancelled

Free format text: ANULADA A PUBLICACAO CODIGO 16.1 NA RPI NO 2500 DE 04/12/2018 POR TER SIDO INDEVIDA.

B09X Republication of the decision to grant [chapter 9.1.3 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 30/11/2011, OBSERVADAS AS CONDICOES LEGAIS.