BR112013010115A2 - separação de enantiômeros derivados de triazina utilizando ácido tartárico - Google Patents
separação de enantiômeros derivados de triazina utilizando ácido tartáricoInfo
- Publication number
- BR112013010115A2 BR112013010115A2 BR112013010115A BR112013010115A BR112013010115A2 BR 112013010115 A2 BR112013010115 A2 BR 112013010115A2 BR 112013010115 A BR112013010115 A BR 112013010115A BR 112013010115 A BR112013010115 A BR 112013010115A BR 112013010115 A2 BR112013010115 A2 BR 112013010115A2
- Authority
- BR
- Brazil
- Prior art keywords
- enantiomers
- triazine
- derived
- separation
- tartaric acid
- Prior art date
Links
- JYEUMXHLPRZUAT-UHFFFAOYSA-N 1,2,3-triazine Chemical compound C1=CN=NN=C1 JYEUMXHLPRZUAT-UHFFFAOYSA-N 0.000 title 1
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 title 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 title 1
- 238000000926 separation method Methods 0.000 title 1
- 235000002906 tartaric acid Nutrition 0.000 title 1
- 239000011975 tartaric acid Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/10—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10306327 | 2010-12-01 | ||
| EP10306327.7 | 2010-12-01 | ||
| PCT/EP2011/071347 WO2012072663A1 (en) | 2010-12-01 | 2011-11-30 | Separation of triazine derivatives enantiomers using tartaric acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112013010115A2 true BR112013010115A2 (pt) | 2016-07-05 |
| BR112013010115B1 BR112013010115B1 (pt) | 2018-12-04 |
Family
ID=45047827
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013010115-6A BR112013010115B1 (pt) | 2010-12-01 | 2011-11-30 | processo de separação de enantiômeros derivados de triazina utilizando ácido tartárico |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US8742103B2 (pt) |
| EP (1) | EP2646422B1 (pt) |
| JP (1) | JP5758010B2 (pt) |
| KR (1) | KR101530924B1 (pt) |
| CN (1) | CN103228635B (pt) |
| AU (1) | AU2011334992B2 (pt) |
| BR (1) | BR112013010115B1 (pt) |
| CA (1) | CA2816357C (pt) |
| CY (1) | CY1117407T1 (pt) |
| DK (1) | DK2646422T3 (pt) |
| EA (1) | EA022300B1 (pt) |
| ES (1) | ES2548038T3 (pt) |
| HR (1) | HRP20151022T1 (pt) |
| HU (1) | HUE026090T2 (pt) |
| IL (1) | IL226053A (pt) |
| ME (1) | ME02208B (pt) |
| MX (1) | MX345822B (pt) |
| PL (1) | PL2646422T3 (pt) |
| PT (1) | PT2646422E (pt) |
| RS (1) | RS54397B1 (pt) |
| SI (1) | SI2646422T1 (pt) |
| SM (1) | SMT201500230B (pt) |
| TW (1) | TWI428311B (pt) |
| WO (1) | WO2012072663A1 (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2020003243A (es) | 2017-10-02 | 2020-09-18 | Poxel | Métodos para tratar la insuficiencia cardíaca con fracción de eyección preservada. |
| WO2019236844A1 (en) | 2018-06-06 | 2019-12-12 | Metavant Sciences Gmbh | Methods of treating subjects having diabetes with chronic kidney disease |
| CN112218623A (zh) | 2018-06-14 | 2021-01-12 | 博希尔公司 | 用于治疗糖尿病的包含三嗪衍生物的薄膜包衣片剂 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2804113B1 (fr) * | 2000-01-26 | 2004-06-18 | Lipha | Derives animes de dihydro-1,3,5-triazine et leurs applications en therapeutique |
| FR2853650B1 (fr) | 2003-04-10 | 2006-07-07 | Merck Sante Sas | Procede de dedoublement d'amines utiles pour le traitement de desordres associes au syndrome d'insulino-resistance |
| US7458318B2 (en) | 2006-02-01 | 2008-12-02 | Speedline Technologies, Inc. | Off-axis illumination assembly and method |
| DE102008007314A1 (de) | 2008-02-02 | 2009-08-06 | Merck Patent Gmbh | Verfahren zur Herstellung von 3,6-Dihydro-1,3,5-triazinderivaten |
| RS54736B1 (sr) | 2008-05-23 | 2016-10-31 | Poxel Sas | Postupak za sintezu derivata 3,6-dihidro-1,3,5-triazina |
-
2011
- 2011-11-30 WO PCT/EP2011/071347 patent/WO2012072663A1/en active Application Filing
- 2011-11-30 TW TW100144035A patent/TWI428311B/zh active
- 2011-11-30 MX MX2013006017A patent/MX345822B/es active IP Right Grant
- 2011-11-30 AU AU2011334992A patent/AU2011334992B2/en not_active Ceased
- 2011-11-30 CN CN201180056898.9A patent/CN103228635B/zh active Active
- 2011-11-30 JP JP2013541326A patent/JP5758010B2/ja active Active
- 2011-11-30 DK DK11788512.9T patent/DK2646422T3/en active
- 2011-11-30 ES ES11788512.9T patent/ES2548038T3/es active Active
- 2011-11-30 US US13/990,924 patent/US8742103B2/en active Active
- 2011-11-30 SI SI201130606T patent/SI2646422T1/sl unknown
- 2011-11-30 KR KR1020137017212A patent/KR101530924B1/ko active IP Right Grant
- 2011-11-30 BR BR112013010115-6A patent/BR112013010115B1/pt not_active IP Right Cessation
- 2011-11-30 CA CA 2816357 patent/CA2816357C/en active Active
- 2011-11-30 EP EP11788512.9A patent/EP2646422B1/en active Active
- 2011-11-30 PL PL11788512T patent/PL2646422T3/pl unknown
- 2011-11-30 EA EA201300650A patent/EA022300B1/ru not_active IP Right Cessation
- 2011-11-30 PT PT117885129T patent/PT2646422E/pt unknown
- 2011-11-30 RS RS20150615A patent/RS54397B1/en unknown
- 2011-11-30 HU HUE11788512A patent/HUE026090T2/en unknown
- 2011-11-30 ME MEP-2015-154A patent/ME02208B/me unknown
-
2013
- 2013-04-29 IL IL226053A patent/IL226053A/en active IP Right Grant
-
2015
- 2015-09-18 CY CY20151100823T patent/CY1117407T1/el unknown
- 2015-09-25 SM SM201500230T patent/SMT201500230B/xx unknown
- 2015-09-28 HR HRP20151022TT patent/HRP20151022T1/hr unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ZA201308086B (en) | Derivatives of 1-anino-2-cyclopropylboronic acid | |
| DK2553113T3 (da) | FREMGANGSMÅDE TIL FREMSTILLING AF L-ORNITHIN UNDER ANVENDELSE AF LysE-OVEREKSPRIMERENDE BAKTERIER | |
| PT2539136T (pt) | Poste de barreira e método de fabrico do mesmo | |
| CO6960555A2 (es) | Procedimiento de preparación de 5-fluoro-1h-pirazolopiridinas sustituidas | |
| DK2552562T3 (da) | Separationsproces | |
| DK2568821T3 (da) | Æggeskal-membran-separationsfremgangsmåde | |
| DK3299356T3 (da) | Fremgangsmåde til fremstilling af pleuromutiliner | |
| HK1207397A1 (en) | Purification of succinic acid | |
| EP2935300A4 (en) | NEW POLYMORPHS FROM LNNT | |
| AP3754A (en) | Method of culturing algae | |
| DK2558472T3 (da) | Fremgangsmåde til fremstilling af dithiin-tetracarboxy-diimider | |
| EP2588428A4 (en) | KINOME ANALYSIS METHODS | |
| BR112013010115A2 (pt) | separação de enantiômeros derivados de triazina utilizando ácido tartárico | |
| GB2501101B (en) | Method of culturing algae | |
| FR2956419B1 (fr) | Elements de construction calorifuges | |
| FR2999175B1 (fr) | Procede d'isolement de diamandoides | |
| EP2782902A4 (en) | DERIVATIVES FROM PHENOXYISOBUTTERIC ACID | |
| EP2791349A4 (en) | SYNTHESIS OF N-ACETYL-D-NEURAMIC ACID | |
| FI20100388A0 (fi) | Viljelymenetelmä | |
| UA21042S (uk) | Комплект бланків | |
| UA22018S (uk) | Комплект етикеток для горілки | |
| UA21913S (uk) | Комплект етикеток для торту | |
| UA21912S (uk) | Комплект етикеток для торту | |
| PL395780A1 (pl) | Uklad samopluczacego zestawu hydroforowo-filtrujacego | |
| UA24546S (uk) | Комплект етикеток для горілки |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 30/11/2011, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B16D | Grant of patent or certificate of addition of invention cancelled |
Free format text: ANULADA A PUBLICACAO CODIGO 16.1 NA RPI NO 2500 DE 04/12/2018 POR TER SIDO INDEVIDA. |
|
| B09X | Republication of the decision to grant [chapter 9.1.3 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 30/11/2011, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 13A ANUIDADE. |