SK9932001A3 - Novel aralkyl amines of spirofuropyridines useful in therapy - Google Patents

Novel aralkyl amines of spirofuropyridines useful in therapy Download PDF

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Publication number
SK9932001A3
SK9932001A3 SK993-2001A SK9932001A SK9932001A3 SK 9932001 A3 SK9932001 A3 SK 9932001A3 SK 9932001 A SK9932001 A SK 9932001A SK 9932001 A3 SK9932001 A3 SK 9932001A3
Authority
SK
Slovakia
Prior art keywords
pyridine
furo
azabicyclo
disease
aminospiro
Prior art date
Application number
SK993-2001A
Other languages
English (en)
Slovak (sk)
Inventor
James Loch Iii
George Mullen
Eifion Phillips
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of SK9932001A3 publication Critical patent/SK9932001A3/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
SK993-2001A 1999-01-15 1999-12-23 Novel aralkyl amines of spirofuropyridines useful in therapy SK9932001A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9900100A SE9900100D0 (sv) 1999-01-15 1999-01-15 New compounds
PCT/SE1999/002478 WO2000042044A1 (en) 1999-01-15 1999-12-23 Novel aralkyl amines of spirofuropyridines useful in therapy

Publications (1)

Publication Number Publication Date
SK9932001A3 true SK9932001A3 (en) 2002-04-04

Family

ID=20414101

Family Applications (1)

Application Number Title Priority Date Filing Date
SK993-2001A SK9932001A3 (en) 1999-01-15 1999-12-23 Novel aralkyl amines of spirofuropyridines useful in therapy

Country Status (34)

Country Link
US (2) US6995167B2 (sv)
EP (1) EP1147114B1 (sv)
JP (1) JP2002534525A (sv)
KR (1) KR100660496B1 (sv)
CN (1) CN1132837C (sv)
AR (1) AR022283A1 (sv)
AT (1) ATE240960T1 (sv)
AU (1) AU775433B2 (sv)
BR (1) BR9916906A (sv)
CA (1) CA2359990A1 (sv)
CZ (1) CZ20012554A3 (sv)
DE (1) DE69908185T2 (sv)
DK (1) DK1147114T3 (sv)
EE (1) EE04528B1 (sv)
ES (1) ES2200590T3 (sv)
HK (1) HK1040517B (sv)
HU (1) HUP0200513A3 (sv)
ID (1) ID30034A (sv)
IL (1) IL144266A0 (sv)
IS (1) IS6000A (sv)
MY (1) MY118109A (sv)
NO (1) NO20013478L (sv)
NZ (1) NZ512733A (sv)
PT (1) PT1147114E (sv)
RU (1) RU2233282C2 (sv)
SA (1) SA00200987B1 (sv)
SE (1) SE9900100D0 (sv)
SI (1) SI1147114T1 (sv)
SK (1) SK9932001A3 (sv)
TR (1) TR200102042T2 (sv)
TW (2) TWI227237B (sv)
UA (1) UA71598C2 (sv)
WO (1) WO2000042044A1 (sv)
ZA (1) ZA200105527B (sv)

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UY31919A (es) 2008-06-20 2010-01-29 Astrazeneca Ab Derivados de dibenzotiazepinas y sus usos-424
CN102256983B (zh) 2008-10-17 2017-04-05 泽农医药公司 螺羟吲哚化合物及其作为治疗剂的用途
DK2355822T3 (da) 2008-11-19 2013-01-28 Envivo Pharmaceuticals Inc behandling af kognitive forstyrrelser med (R)-7-chlor-N-(quinuclidin-3-yl)benzoe[b]thiophen-2-carboxamid og farmaceutisk acceptable salte deraf
TW201031664A (en) 2009-01-26 2010-09-01 Targacept Inc Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide
JP5808319B2 (ja) * 2009-05-11 2015-11-10 フォルム ファーマシューティカルズ、インコーポレイテッド アセチルコリンエステラーゼ阻害剤と組み合わせた特定のα７ニコチン酸受容体を用いた認知障害の治療
AR077252A1 (es) 2009-06-29 2011-08-10 Xenon Pharmaceuticals Inc Enantiomeros de compuestos de espirooxindol y sus usos como agentes terapeuticos
AU2010306768B2 (en) 2009-10-14 2016-08-04 Xenon Pharmaceuticals Inc. Synthetic methods for spiro-oxindole compounds
EP2538919B1 (en) 2010-02-26 2017-07-12 Xenon Pharmaceuticals Inc. Pharmaceutical compositions of spiro-oxindole compound for topical administration and their use as therapeutic agents
RU2577334C2 (ru) 2010-05-17 2016-03-20 Энвиво Фармасьютикалз, Инк. КРИСТАЛЛИЧЕСКАЯ ФОРМА МОНОГИДРАТА ГИДРОХЛОРИДА (R)-7-ХЛОР-N-(ХИНУКЛИДИН-3-ИЛ)БЕНЗО[b]ТИОФЕН-2-КАРБОКСАМИДА
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Also Published As

Publication number Publication date
NO20013478L (no) 2001-09-14
PT1147114E (pt) 2003-10-31
CN1132837C (zh) 2003-12-31
US20050250802A1 (en) 2005-11-10
HK1040517A1 (en) 2002-06-14
JP2002534525A (ja) 2002-10-15
IS6000A (is) 2001-07-12
ZA200105527B (en) 2002-10-04
US20030149065A1 (en) 2003-08-07
EE200100370A (et) 2002-10-15
US6995167B2 (en) 2006-02-07
HUP0200513A3 (en) 2004-07-28
KR20010086167A (ko) 2001-09-08
KR100660496B1 (ko) 2006-12-22
NZ512733A (en) 2003-08-29
TR200102042T2 (tr) 2002-05-21
SI1147114T1 (en) 2003-12-31
SA00200987B1 (ar) 2006-11-07
SE9900100D0 (sv) 1999-01-15
ID30034A (id) 2001-11-01
US7196096B2 (en) 2007-03-27
ATE240960T1 (de) 2003-06-15
CN1337964A (zh) 2002-02-27
NO20013478D0 (no) 2001-07-13
WO2000042044A1 (en) 2000-07-20
AU775433B2 (en) 2004-07-29
DE69908185D1 (de) 2003-06-26
BR9916906A (pt) 2001-10-30
ES2200590T3 (es) 2004-03-01
TW200413387A (en) 2004-08-01
IL144266A0 (en) 2002-05-23
TWI227237B (en) 2005-02-01
DE69908185T2 (de) 2004-06-03
EP1147114B1 (en) 2003-05-21
AU2334300A (en) 2000-08-01
HK1040517B (zh) 2003-09-05
DK1147114T3 (da) 2003-09-15
EE04528B1 (et) 2005-08-15
AR022283A1 (es) 2002-09-04
UA71598C2 (en) 2004-12-15
CA2359990A1 (en) 2000-07-20
MY118109A (en) 2004-08-30
CZ20012554A3 (cs) 2002-01-16
HUP0200513A2 (en) 2002-06-29
EP1147114A1 (en) 2001-10-24
RU2233282C2 (ru) 2004-07-27

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