SK682003A3 - Carbamate and thiocarbamate podophyllotoxin derivatives, preparation method and pharmaceutical compositions containing them - Google Patents

Carbamate and thiocarbamate podophyllotoxin derivatives, preparation method and pharmaceutical compositions containing them Download PDF

Info

Publication number
SK682003A3
SK682003A3 SK68-2003A SK682003A SK682003A3 SK 682003 A3 SK682003 A3 SK 682003A3 SK 682003 A SK682003 A SK 682003A SK 682003 A3 SK682003 A3 SK 682003A3
Authority
SK
Slovakia
Prior art keywords
linear
branched
formula
group
alkyl
Prior art date
Application number
SK68-2003A
Other languages
English (en)
Slovak (sk)
Inventor
Claude Monneret
Emmanuel Bertounesque
Philippe Meresse
Ghanem Atassi
Alain Pierre
John Hickman
Bruno Pfeiffer
Pierre Renard
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of SK682003A3 publication Critical patent/SK682003A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
SK68-2003A 2000-06-20 2001-06-19 Carbamate and thiocarbamate podophyllotoxin derivatives, preparation method and pharmaceutical compositions containing them SK682003A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0007823A FR2810321B1 (fr) 2000-06-20 2000-06-20 Nouveaux derives de podophyllotoxine carbamate et thiocarbamate, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR2001/001908 WO2001098307A1 (fr) 2000-06-20 2001-06-19 Derives de podophyllotoxine carbamate et thiocarbamate, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
SK682003A3 true SK682003A3 (en) 2003-05-02

Family

ID=8851423

Family Applications (1)

Application Number Title Priority Date Filing Date
SK68-2003A SK682003A3 (en) 2000-06-20 2001-06-19 Carbamate and thiocarbamate podophyllotoxin derivatives, preparation method and pharmaceutical compositions containing them

Country Status (26)

Country Link
US (1) US6878746B2 (no)
EP (1) EP1292597B1 (no)
JP (1) JP3909017B2 (no)
KR (1) KR100513575B1 (no)
CN (1) CN1191257C (no)
AR (1) AR028961A1 (no)
AT (1) ATE261975T1 (no)
AU (2) AU2001269190B2 (no)
BR (1) BR0111854A (no)
CA (1) CA2413515C (no)
CZ (1) CZ2003172A3 (no)
DE (1) DE60102378T2 (no)
DK (1) DK1292597T3 (no)
EA (1) EA005200B1 (no)
ES (1) ES2217159T3 (no)
FR (1) FR2810321B1 (no)
HK (1) HK1055424A1 (no)
HU (1) HUP0301612A3 (no)
MX (1) MXPA02012570A (no)
NO (1) NO20026004L (no)
PL (1) PL359460A1 (no)
PT (1) PT1292597E (no)
SK (1) SK682003A3 (no)
TR (1) TR200400592T4 (no)
WO (1) WO2001098307A1 (no)
ZA (1) ZA200209639B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003082876A1 (en) * 2002-03-28 2003-10-09 Council Of Scientific And Industrial Research 4-beta-1''-`(2''-(substituted benzoyl)anilino! podophyllotoxin analogues useful as anticancer agents
FR2869035B1 (fr) 2004-04-16 2006-07-14 Pierre Fabre Medicament Sa Derives (poly)aminoalkylaminoacetamide d'epipodophyllotoxine leur procede de preparation et leurs applications en therapeutique comme agent anticancereux
WO2009141738A2 (en) * 2008-05-23 2009-11-26 The University Of British Columbia Modified drugs for use in liposomal nanoparticles
FR2935143B1 (fr) 2008-08-19 2010-12-03 Pf Medicament Nouveaus derives (poly)aminoalkylaminoalkylamides, alkyl-urees, ou alkyl-sulfonamides d'epipodophyllotoxine, leur procede de preparation et leur application en therapeuthique comme agent cancereux
CN103080125A (zh) 2010-07-02 2013-05-01 安吉奥开米公司 用于治疗性结合物的短且含d氨基酸的多肽及其使用
CN107964014A (zh) * 2017-10-28 2018-04-27 兰州大学 一种邻硝基芳酰化衍生物类化合物、制备方法及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1455540A (fr) * 1964-11-18 1966-10-14 Sandoz Sa Nouveaux dérivés de la podophyllotoxine et leur préparation
JPH01117885A (ja) * 1987-10-30 1989-05-10 Dai Ichi Seiyaku Co Ltd 新規ボドフィロトキシン誘導体及びその製造法
US6566393B1 (en) * 2002-06-21 2003-05-20 The University Of North Carolina At Chapel Hill Etoposide analogs and methods of use thereof

Also Published As

Publication number Publication date
FR2810321B1 (fr) 2002-07-26
US6878746B2 (en) 2005-04-12
MXPA02012570A (es) 2003-04-10
ATE261975T1 (de) 2004-04-15
JP2004501158A (ja) 2004-01-15
HUP0301612A3 (en) 2005-08-29
NO20026004D0 (no) 2002-12-13
ES2217159T3 (es) 2004-11-01
HK1055424A1 (en) 2004-01-09
KR20030025246A (ko) 2003-03-28
CZ2003172A3 (cs) 2003-05-14
BR0111854A (pt) 2003-05-13
DE60102378T2 (de) 2005-02-24
CN1191257C (zh) 2005-03-02
AU2001269190B2 (en) 2005-03-17
JP3909017B2 (ja) 2007-04-25
NO20026004L (no) 2002-12-13
CA2413515A1 (fr) 2001-12-27
PL359460A1 (en) 2004-08-23
KR100513575B1 (ko) 2005-09-09
EP1292597B1 (fr) 2004-03-17
ZA200209639B (en) 2003-11-27
DE60102378D1 (de) 2004-04-22
EP1292597A1 (fr) 2003-03-19
CN1437604A (zh) 2003-08-20
AR028961A1 (es) 2003-05-28
AU6919001A (en) 2002-01-02
PT1292597E (pt) 2004-06-30
TR200400592T4 (tr) 2004-04-21
WO2001098307A1 (fr) 2001-12-27
DK1292597T3 (da) 2004-07-12
US20040101574A1 (en) 2004-05-27
FR2810321A1 (fr) 2001-12-21
HUP0301612A2 (hu) 2003-09-29
CA2413515C (fr) 2008-02-05
EA200300029A1 (ru) 2003-06-26
EA005200B1 (ru) 2004-12-30

Similar Documents

Publication Publication Date Title
US9403840B2 (en) (Poly) aminoacetamide derivatives of epipodophyllotoxin their process of preparation and their applications in therapeutics as anticancer agents
KR20080032007A (ko) 신규의 캄토테신 유도체 화합물, 그들의 제조 방법 및 상기화합물을 포함하는 약제학적 조성물
SK682003A3 (en) Carbamate and thiocarbamate podophyllotoxin derivatives, preparation method and pharmaceutical compositions containing them
US6281198B1 (en) 9-(3,5-dimethoxyphenyl)-5,8,8a,9-tetrahydrofuro-[3′,4′:6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one compounds
US20060247246A1 (en) 9-Amino-podophyllotoxin derivatives, method for the production thereof and pharmaceutical compositions containing said derivatives
NZ523172A (en) Carbamate and thiocarbamate podophyllotoxin derivatives, preparation method and pharmaceutical compositions containing them
KR100742060B1 (ko) 벤조[ｂ]피라노[3,2-ｈ]아크리딘-7-온 신나메이트 화합물,이들의 제조방법, 및 이들을 함유하는 약제학적 조성물
EA014754B1 (ru) Новые соединения - аналоги камптотецина, способ их получения и фармацевтические композиции, которые их содержат
MXPA97000644A (en) Derivatives of substitute campptotecine and process for its preparation