SK6222003A3 - Naphthalene derivatives, process for their preparation and their use in pharmaceutical compositions - Google Patents

Naphthalene derivatives, process for their preparation and their use in pharmaceutical compositions Download PDF

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Publication number
SK6222003A3
SK6222003A3 SK622-2003A SK6222003A SK6222003A3 SK 6222003 A3 SK6222003 A3 SK 6222003A3 SK 6222003 A SK6222003 A SK 6222003A SK 6222003 A3 SK6222003 A3 SK 6222003A3
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Slovakia
Prior art keywords
carbon atoms
hydrogen
naphthyl
alkyl
mmol
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SK622-2003A
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English (en)
Slovak (sk)
Inventor
Christopher Thomas Brain
Andrew James Culshaw
Edward Karol Dziadulewicz
Ulrich Schopfer
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Novartis Ag
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Publication of SK6222003A3 publication Critical patent/SK6222003A3/sk

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    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/14—Thiadiazoles; Hydrogenated thiadiazoles condensed with carbocyclic rings or ring systems
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    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
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    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
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    • C07F9/32—Esters thereof
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    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

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ZA200302916B (en) 2004-04-23
JP4836396B2 (ja) 2011-12-14
CZ20031424A3 (cs) 2003-08-13
CA2427844A1 (en) 2002-05-30
HUP0302125A2 (hu) 2003-10-28
NO330005B1 (no) 2011-02-07
EP2338886A2 (de) 2011-06-29
CA2427844C (en) 2012-04-17
JP2008050361A (ja) 2008-03-06
ATE540013T1 (de) 2012-01-15
US7045533B2 (en) 2006-05-16
WO2002042248A2 (en) 2002-05-30
BR0115605A (pt) 2003-09-16
AR035505A1 (es) 2004-06-02
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KR20030043994A (ko) 2003-06-02
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KR100810948B1 (ko) 2008-03-10
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