SK484188A3 - DERIVATIVES OF BENZOPYRANE, INTERMEDIATE PRODUCTS FOR PRODUCINGì THEM AND PHARMACEUTICAL COMPOSITIONS ON THEIR BASE - Google Patents
DERIVATIVES OF BENZOPYRANE, INTERMEDIATE PRODUCTS FOR PRODUCINGì THEM AND PHARMACEUTICAL COMPOSITIONS ON THEIR BASE Download PDFInfo
- Publication number
- SK484188A3 SK484188A3 SK4841-88A SK484188A SK484188A3 SK 484188 A3 SK484188 A3 SK 484188A3 SK 484188 A SK484188 A SK 484188A SK 484188 A3 SK484188 A3 SK 484188A3
- Authority
- SK
- Slovakia
- Prior art keywords
- benzopyran
- dimethyl
- oxide
- dihydro
- pyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB878715839A GB8715839D0 (en) | 1987-07-06 | 1987-07-06 | Benzopyran derivatives |
GB888810212A GB8810212D0 (en) | 1987-07-06 | 1988-04-29 | Benzopyran derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
SK484188A3 true SK484188A3 (en) | 1998-05-06 |
SK279037B6 SK279037B6 (sk) | 1998-05-06 |
Family
ID=26292440
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SK4841-88A SK279037B6 (sk) | 1987-07-06 | 1988-07-04 | Deriváty benzopyránu, medziprodukty pre ich výrobu |
Country Status (27)
Country | Link |
---|---|
US (2) | US4971982A (no) |
EP (1) | EP0298452B1 (no) |
JP (1) | JP2683581B2 (no) |
CN (1) | CN1023404C (no) |
AR (1) | AR245710A1 (no) |
AT (1) | ATE91127T1 (no) |
AU (1) | AU613646B2 (no) |
CA (1) | CA1334094C (no) |
CZ (1) | CZ285970B6 (no) |
DE (1) | DE3882095D1 (no) |
DK (1) | DK370988A (no) |
DZ (1) | DZ1227A1 (no) |
ES (1) | ES2056859T3 (no) |
FI (1) | FI90079C (no) |
HU (2) | HU202513B (no) |
IE (1) | IE62258B1 (no) |
IL (1) | IL86923A (no) |
IS (1) | IS1596B (no) |
MC (1) | MC1953A1 (no) |
MX (1) | MX174083B (no) |
NO (1) | NO170727C (no) |
NZ (1) | NZ225163A (no) |
PH (1) | PH27153A (no) |
PT (1) | PT87913B (no) |
SK (1) | SK279037B6 (no) |
SU (1) | SU1757466A3 (no) |
YU (1) | YU46918B (no) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5387587A (en) * | 1986-12-23 | 1995-02-07 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Chroman derivatives |
US5284838A (en) * | 1987-06-23 | 1994-02-08 | Elf Sanofi | Use of 2,2-dimethylchroman-3-ol derivatives in the treatment of asthma |
US4971982A (en) * | 1987-07-06 | 1990-11-20 | Hoffmann-La Roche Inc. | Benzopyran derivatives |
AU628331B2 (en) * | 1988-05-06 | 1992-09-17 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Chroman derivatives |
DE3918041A1 (de) * | 1989-06-02 | 1990-12-06 | Merck Patent Gmbh | Chromanderivate |
DE3922392A1 (de) * | 1989-07-07 | 1991-01-17 | Merck Patent Gmbh | Chromanderivate |
DE3924417A1 (de) * | 1989-07-24 | 1991-01-31 | Merck Patent Gmbh | Chromanderivate |
DE3926001A1 (de) * | 1989-08-05 | 1991-02-07 | Merck Patent Gmbh | Chromanderivate |
US5616610A (en) * | 1989-12-22 | 1997-04-01 | Astra Aktiebolag | (R)-5-carbamoyl-8-fluoro-3-N,N-disubstituted-amino-3,4-dihydro-2H-1-benzopyrans |
US5420151A (en) * | 1989-12-22 | 1995-05-30 | Aktiebolaget Astra | Chroman derivatives |
CN1060467A (zh) * | 1990-09-25 | 1992-04-22 | 武田药品工业株式会社 | 1,3-苯并嗪衍生物、其生产方法和用途 |
CA2061179A1 (en) * | 1991-02-18 | 1992-08-19 | Ryuji Tsuzuki | Oxzazinobenzazole compounds |
DE4115465A1 (de) * | 1991-05-11 | 1992-11-12 | Beiersdorf Ag | Neue in 4-stellung durch aryl oder n-heteroaryl substituierte 2h-benzo(b)pyran-derivate, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen |
KR950009863B1 (ko) * | 1991-05-22 | 1995-08-29 | 재단법인한국화학연구소 | 벤조피란 유도체와 그의 제조방법 |
FR2698873B1 (fr) * | 1992-12-07 | 1995-02-24 | Lipha | Benzocycloheptènes, benzoxépines et benzothiépines activateurs des canaux potassiques, procédé de préparation, composition pharmaceutique les contenant. |
TW258735B (no) * | 1992-08-17 | 1995-10-01 | Chugai Pharmaceutical Co Ltd | |
ES2064228B1 (es) * | 1992-10-19 | 1995-09-01 | Uriach & Cia Sa J | Nuevas tetralonas con actividad farmacologica, composiciones que las contienen y procedimiento para su preparacion. |
US5416097A (en) * | 1993-05-19 | 1995-05-16 | Berlex Laboratories, Inc. | Potassium channel activators/openers |
US5837702A (en) * | 1993-10-07 | 1998-11-17 | Bristol-Myers Squibb Co. | 4-arylamino-benzopyran and related compounds |
KR0170534B1 (ko) * | 1993-11-10 | 1999-02-18 | 미즈노 시게루 | 크로만 유도체 및 그의 제약학적 용도 |
CN1065529C (zh) * | 1994-06-09 | 2001-05-09 | 爱斯制药株式会社 | 4-喹啉酮衍生物及其盐 |
US5470861A (en) * | 1994-08-04 | 1995-11-28 | Hoffmann-La Roche Inc. | Method of promoting hair growth |
US5629429A (en) * | 1995-06-07 | 1997-05-13 | Bristol-Myers Squibb Company | Process for preparing 4-arylamino-benzopyran and related compounds |
US5612323A (en) * | 1995-06-07 | 1997-03-18 | Bristol-Myers Squibb Company | Phosphinic ester substituted benzopyran derivatives |
US5869478A (en) * | 1995-06-07 | 1999-02-09 | Bristol-Myers Squibb Company | Sulfonamido substituted benzopyran derivatives |
US5612370A (en) * | 1995-06-07 | 1997-03-18 | Bristol-Myers Squibb Company | Phenylglycine and phenylalaninen amido benzopyran derivatives |
KR100691511B1 (ko) * | 1995-11-09 | 2007-04-19 | 다우 아그로사이언시즈 엘엘씨 | 크로만카복실레이트의제조방법 |
JP3885900B2 (ja) * | 1996-03-22 | 2007-02-28 | 大日本インキ化学工業株式会社 | ベンゾピラン誘導体及びそれを有効成分とする心臓疾患治療剤 |
WO1999001453A1 (en) * | 1997-07-02 | 1999-01-14 | F. Hoffmann-La Roche Ag | A process for the manufacture of optically active chromanylpyridine derivatives |
US7045519B2 (en) * | 1998-06-19 | 2006-05-16 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
JP4533534B2 (ja) | 1998-06-19 | 2010-09-01 | ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド | グリコーゲンシンターゼキナーゼ3のインヒビター |
US6455554B1 (en) | 1999-06-07 | 2002-09-24 | Targacept, Inc. | Oxopyridinyl pharmaceutical compositions and methods for use |
FI20010233A0 (fi) * | 2001-02-08 | 2001-02-08 | Orion Corp | Menetelmä sydämen vajaatoiminnan hoitoon |
AR035087A1 (es) * | 2001-08-09 | 2004-04-14 | Syngenta Participations Ag | Piridil-alquinos y piridil-n-oxido-alquinos herbicidas activos, procedimiento para su preparacion, composicion herbicida y para inhibir el crecimiento de plantas, metodo para el control del crecimiento de plantas indeseables , y metodo para la inhibicion del crecimiento de plantas |
AR040413A1 (es) * | 2002-05-31 | 2005-04-06 | Syngenta Participations Ag | Heterociclilalquinos activos como herbicidas |
WO2007027959A1 (en) * | 2005-09-01 | 2007-03-08 | Janssen Pharmaceutica N.V. | Novel benzopyran derivatives as potassium channel openers |
CA2620846A1 (en) * | 2005-09-01 | 2007-03-08 | Janssen Pharmaceutica N.V. | Benzopyran and pyranopyridine derivatives as potassium channel openers |
WO2008072801A1 (en) * | 2006-12-13 | 2008-06-19 | Seoul National University Industry Foundation | Compounds with embedded benzopyran motif for core structures and preparation method thereof |
CN103819395B (zh) * | 2014-02-24 | 2016-05-25 | 蚌埠中实化学技术有限公司 | 一种制备2-碘-5-苯基吡啶的方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1583811A (en) * | 1977-05-09 | 1981-02-04 | Laroche Navarron Sa | Chromene derivatives |
US4563468A (en) * | 1979-09-13 | 1986-01-07 | Burroughs Wellcome Co. | Chemotherapeutic agents |
HU184359B (en) * | 1980-12-16 | 1984-08-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing substituted acyl-carbamides |
US4443459A (en) * | 1981-05-26 | 1984-04-17 | Banyu Pharmaceutical Co., Ltd. | α-Tocopheryl ester of 5-substituted picolinic acid and hypotensive composition containing it |
GB2107706A (en) * | 1981-09-25 | 1983-05-05 | Beecham Group Plc | Benzopyrans |
EP0107423B1 (en) * | 1982-10-19 | 1986-07-23 | Beecham Group Plc | Novel chromans and chromenes |
ATE56007T1 (de) * | 1984-06-22 | 1990-09-15 | Beecham Group Plc | Wirksame benzopyranverbindungen. |
EP0218373B1 (en) * | 1985-09-11 | 1990-03-07 | Beecham Group Plc | Chroman derivatives and analogues having antihypertensive activity |
PT84806B (pt) * | 1986-05-03 | 1989-12-29 | Beecham Group Plc | Processo para a preparacao de benzopiranos |
IL86798A (en) * | 1987-06-23 | 1992-12-01 | Sanofi Sa | 2,2-dimethylchroman-3-ol derivatives, their preparation and pharmaceutical compositions containing them |
US4971982A (en) * | 1987-07-06 | 1990-11-20 | Hoffmann-La Roche Inc. | Benzopyran derivatives |
-
1988
- 1988-06-23 US US07/210,692 patent/US4971982A/en not_active Expired - Fee Related
- 1988-06-24 NZ NZ225163A patent/NZ225163A/en unknown
- 1988-06-30 AU AU18556/88A patent/AU613646B2/en not_active Ceased
- 1988-06-30 IL IL8692388A patent/IL86923A/en not_active IP Right Cessation
- 1988-07-03 DZ DZ880098A patent/DZ1227A1/fr active
- 1988-07-04 HU HU883471A patent/HU202513B/hu not_active IP Right Cessation
- 1988-07-04 AR AR88311317A patent/AR245710A1/es active
- 1988-07-04 DK DK370988A patent/DK370988A/da not_active Application Discontinuation
- 1988-07-04 SK SK4841-88A patent/SK279037B6/sk unknown
- 1988-07-04 MC MC881987A patent/MC1953A1/xx unknown
- 1988-07-04 CZ CS884841A patent/CZ285970B6/cs not_active IP Right Cessation
- 1988-07-05 YU YU130288A patent/YU46918B/sh unknown
- 1988-07-05 MX MX1216888A patent/MX174083B/es unknown
- 1988-07-05 NO NO883007A patent/NO170727C/no not_active IP Right Cessation
- 1988-07-05 PT PT87913A patent/PT87913B/pt not_active IP Right Cessation
- 1988-07-05 CA CA000571115A patent/CA1334094C/en not_active Expired - Fee Related
- 1988-07-05 IS IS3369A patent/IS1596B/is unknown
- 1988-07-05 CN CN88104200A patent/CN1023404C/zh not_active Expired - Fee Related
- 1988-07-05 JP JP63166068A patent/JP2683581B2/ja not_active Expired - Lifetime
- 1988-07-05 IE IE204388A patent/IE62258B1/en not_active IP Right Cessation
- 1988-07-05 SU SU884356220A patent/SU1757466A3/ru active
- 1988-07-06 ES ES88110789T patent/ES2056859T3/es not_active Expired - Lifetime
- 1988-07-06 PH PH37176A patent/PH27153A/en unknown
- 1988-07-06 EP EP88110789A patent/EP0298452B1/de not_active Expired - Lifetime
- 1988-07-06 DE DE8888110789T patent/DE3882095D1/de not_active Expired - Fee Related
- 1988-07-06 AT AT88110789T patent/ATE91127T1/de not_active IP Right Cessation
- 1988-07-06 FI FI883232A patent/FI90079C/fi not_active IP Right Cessation
-
1990
- 1990-09-11 US US07/580,881 patent/US5118694A/en not_active Expired - Fee Related
-
1995
- 1995-06-19 HU HU95P/P00257P patent/HU211870A9/hu unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SK484188A3 (en) | DERIVATIVES OF BENZOPYRANE, INTERMEDIATE PRODUCTS FOR PRODUCINGì THEM AND PHARMACEUTICAL COMPOSITIONS ON THEIR BASE | |
EP0420511B1 (en) | Heterocyclic derivatives | |
AU641953B2 (en) | Benzoxazine derivatives, pharmaceutical compositions containing them and processes for their production | |
Gericke et al. | 3-Methyl-2H-1-benzopyran potassium channel activators | |
PL140462B1 (en) | Method of obtaining novel derivatives of 1-hydroxyphenyl-1,3-dioxancis-5-ylalkenocarboxylic acids | |
US5387587A (en) | Chroman derivatives | |
JPH0561273B2 (no) | ||
CS203970B2 (en) | Method of producing novel heterocyclyl-oxy-hydroxy-amino-propanes | |
US5217977A (en) | Heterocyclic cycloalkanes | |
DE69020008T2 (de) | Heterozyklische Ether als 5-Lipoxygenase-hemmer. | |
HUT56096A (en) | Process for producing chromane derivatives and pharmaceutical compositions containing them | |
JP2874912B2 (ja) | クロマン誘導体 | |
JPS6046115B2 (ja) | テトラヒドロピリジン及びピペリジン誘導体の製法 | |
US5045550A (en) | Substituted tetrahydropyridines as central nervous system agents | |
US5118691A (en) | Substituted tetrahydropyridines as central nervous system agents | |
JPS63225356A (ja) | ジヒドロピリジン誘導体 | |
EP0586405B1 (de) | NEUE IN 4-STELLUNG DURCH ARYL ODER N-HETEROARYL SUBSTITUIERTE 2H-BENZO[b]PYRAN-DERIVATE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG SOWIE DIE VERBINDUNGEN ENTHALTENDE ZUBEREITUNGEN | |
KR960012213B1 (ko) | 벤조피란 유도체, 이의 제조방법 및 이를 함유하는 약제 | |
JPH04290883A (ja) | キノリニウム塩およびその製造方法 | |
KR20050112948A (ko) | 1h-피리딘-2-온 유도체 |