SK287086B6 - 2H-1-Benzopyránové deriváty, farmaceutické prostriedky s ich obsahom a ich použitie - Google Patents

2H-1-Benzopyránové deriváty, farmaceutické prostriedky s ich obsahom a ich použitie Download PDF

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Publication number
SK287086B6
SK287086B6 SK939-2003A SK9392003A SK287086B6 SK 287086 B6 SK287086 B6 SK 287086B6 SK 9392003 A SK9392003 A SK 9392003A SK 287086 B6 SK287086 B6 SK 287086B6
Authority
SK
Slovakia
Prior art keywords
alkyl
phenyl
compound
benzopyran
solution
Prior art date
Application number
SK939-2003A
Other languages
English (en)
Slovak (sk)
Other versions
SK9392003A3 (en
Inventor
Maurizio Delcanale
Gabriele Amari
Elisabetta Armani
Maurizio Civelli
Elisabetta Galbiati
Original Assignee
Chiesi Farmaceutici S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP01101521A external-priority patent/EP1229036B1/en
Priority claimed from EP01118682A external-priority patent/EP1281710A1/en
Application filed by Chiesi Farmaceutici S.P.A. filed Critical Chiesi Farmaceutici S.P.A.
Publication of SK9392003A3 publication Critical patent/SK9392003A3/sk
Publication of SK287086B6 publication Critical patent/SK287086B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
SK939-2003A 2001-01-24 2002-01-21 2H-1-Benzopyránové deriváty, farmaceutické prostriedky s ich obsahom a ich použitie SK287086B6 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01101521A EP1229036B1 (en) 2001-01-24 2001-01-24 2H-1-benzopyran derivatives, processes for their preparation and pharmaceutical compositions thereof
EP01118682A EP1281710A1 (en) 2001-08-03 2001-08-03 2H-1-benzopyran derivatives, processes for their preparation and pharmaceutical compositions thereof
PCT/EP2002/000567 WO2002059113A1 (en) 2001-01-24 2002-01-21 2h-1-benzopyran derivatives, processes for their preparation and pharmaceutical compositions thereof

Publications (2)

Publication Number Publication Date
SK9392003A3 SK9392003A3 (en) 2003-12-02
SK287086B6 true SK287086B6 (sk) 2009-11-05

Family

ID=26076450

Family Applications (1)

Application Number Title Priority Date Filing Date
SK939-2003A SK287086B6 (sk) 2001-01-24 2002-01-21 2H-1-Benzopyránové deriváty, farmaceutické prostriedky s ich obsahom a ich použitie

Country Status (26)

Country Link
US (1) US6951883B2 (https=)
EP (1) EP1355906B1 (https=)
JP (1) JP4332349B2 (https=)
CN (1) CN1261431C (https=)
AT (1) ATE286894T1 (https=)
AU (1) AU2002237282B2 (https=)
BR (1) BR0207066A (https=)
CA (1) CA2435775A1 (https=)
CZ (1) CZ20032014A3 (https=)
DE (1) DE60202590T2 (https=)
DK (1) DK1355906T3 (https=)
DZ (1) DZ3459A1 (https=)
EA (1) EA006158B1 (https=)
ES (1) ES2236485T3 (https=)
HU (1) HUP0401018A3 (https=)
IL (2) IL157065A0 (https=)
MA (1) MA26982A1 (https=)
MX (1) MXPA03006505A (https=)
NO (1) NO327808B1 (https=)
NZ (1) NZ527144A (https=)
PL (1) PL365062A1 (https=)
PT (1) PT1355906E (https=)
SI (1) SI1355906T1 (https=)
SK (1) SK287086B6 (https=)
TN (1) TNSN03043A1 (https=)
WO (1) WO2002059113A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005201855B2 (en) * 2004-09-21 2012-03-29 Marshall Edwards, Inc. Chroman derived compounds and formulations thereof for use in therapy
JP4913056B2 (ja) * 2004-09-21 2012-04-11 マーシャル エドワーズ，インコーポレーテッド 置換クロマン誘導体、医薬品、および治療における使用
EP1794141B1 (en) 2004-09-21 2011-11-09 Marshall Edwards, Inc. Substituted chroman derivatives, medicaments and use in therapy
JP4976649B2 (ja) * 2004-09-21 2012-07-18 マーシャル エドワーズ，インク． 化合物
EP2436680B1 (en) * 2004-09-21 2016-05-18 Marshall Edwards, Inc. Chroman derivatives, medicaments and use in therapy
US8080675B2 (en) 2004-09-21 2011-12-20 Marshall Edwards, Inc. Chroman derivatives, medicaments and use in therapy
CN101444499B (zh) * 2007-11-26 2012-12-05 湘北威尔曼制药股份有限公司 一种化合物及其组合物的新用途
JP6013349B2 (ja) 2010-11-01 2016-10-25 メイ ファーマ, インク.Mei Pharma, Inc. 癌の処置のためのイソフラボノイド化合物および方法
EA031077B1 (ru) 2013-06-19 2018-11-30 Серагон Фармасьютикалз, Инк. Модулятор рецептора эстрогена и его применения
CN116139125A (zh) 2015-02-02 2023-05-23 梅制药公司 联合治疗
ES3039455T3 (en) * 2016-11-17 2025-10-21 Sanofi Sa Novel substituted n-(3-fluoropropyl)-pyrrolidine compounds, processes for their preparation and therapeutic uses thereof
US20200215025A1 (en) * 2017-09-15 2020-07-09 Norbio No. 1 Pty Ltd Treatment of excitotoxicity
CN112225716A (zh) * 2020-10-30 2021-01-15 陕西嘉禾生物科技股份有限公司 一种鹰嘴豆牙素a的合成方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3374245A (en) * 1964-04-01 1968-03-19 Ciba Geigy Corp Unsaturated oxacycles
DE1518002C3 (de) * 1965-01-02 1975-01-23 Merck Patent Gmbh, 6100 Darmstadt Isoflavane und Isoflavene und Verfahren zu Ihrer Herstellung sowie diese enthaltende Arzneimittel
US5280040A (en) * 1993-03-11 1994-01-18 Zymogenetics, Inc. Methods for reducing bone loss using centchroman derivatives
US5985306A (en) 1996-10-28 1999-11-16 Novo Nordisk A/S (+)-enantiomers of cis-3,4-chroman derivatives useful in prevention or treatment of estrogen diseases or syndromes
AU744403B2 (en) 1996-10-28 2002-02-21 Novo Nordisk A/S Novel trans-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
US6153768A (en) 1996-12-13 2000-11-28 C & C Research Laboratories Benzopyran derivatives
KR20000001793A (ko) 1998-06-13 2000-01-15 이경하 신규한 벤조피란 또는 티오벤조피란 유도체
EP1140889B1 (en) 1998-12-30 2003-08-27 Signal Pharmaceuticals, Inc. Compounds and methods for modulation of estrogen receptors

Also Published As

Publication number Publication date
NZ527144A (en) 2005-03-24
HUP0401018A3 (en) 2007-05-29
NO20033318D0 (no) 2003-07-23
JP2004517151A (ja) 2004-06-10
DZ3459A1 (fr) 2002-08-01
IL157065A0 (en) 2004-02-08
ATE286894T1 (de) 2005-01-15
CN1261431C (zh) 2006-06-28
DE60202590D1 (de) 2005-02-17
DK1355906T3 (da) 2005-05-30
US20040106595A1 (en) 2004-06-03
TNSN03043A1 (en) 2005-12-23
EP1355906A1 (en) 2003-10-29
EA200300727A1 (ru) 2004-02-26
IL157065A (en) 2010-05-17
BR0207066A (pt) 2004-03-30
AU2002237282B2 (en) 2007-02-15
PL365062A1 (en) 2004-12-27
NO20033318L (no) 2003-09-24
CA2435775A1 (en) 2002-08-01
CN1487934A (zh) 2004-04-07
EP1355906B1 (en) 2005-01-12
HK1060558A1 (en) 2004-08-13
NO327808B1 (no) 2009-09-28
EA006158B1 (ru) 2005-10-27
SI1355906T1 (en) 2005-06-30
WO2002059113A1 (en) 2002-08-01
MA26982A1 (fr) 2004-12-20
DE60202590T2 (de) 2005-12-29
HUP0401018A2 (hu) 2004-09-28
PT1355906E (pt) 2005-05-31
CZ20032014A3 (cs) 2003-12-17
US6951883B2 (en) 2005-10-04
ES2236485T3 (es) 2005-07-16
MXPA03006505A (es) 2004-04-21
SK9392003A3 (en) 2003-12-02
JP4332349B2 (ja) 2009-09-16

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20090918