SK285562B6 - Kryštálová modifikácia C kyseliny 8-kyano-1-cyklopropyl-7-(1S,6S- 2,8-diazabicyklo[4.3.0]nonan-8-yl)-6-fluór-1,4-dihydro-4-oxo-3- chinolínkarboxylovej, spôsob jej výroby a jej použitie - Google Patents

Kryštálová modifikácia C kyseliny 8-kyano-1-cyklopropyl-7-(1S,6S- 2,8-diazabicyklo[4.3.0]nonan-8-yl)-6-fluór-1,4-dihydro-4-oxo-3- chinolínkarboxylovej, spôsob jej výroby a jej použitie Download PDF

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Publication number
SK285562B6
SK285562B6 SK1195-2001A SK11952001A SK285562B6 SK 285562 B6 SK285562 B6 SK 285562B6 SK 11952001 A SK11952001 A SK 11952001A SK 285562 B6 SK285562 B6 SK 285562B6
Authority
SK
Slovakia
Prior art keywords
diazabicyclo
cyclopropyl
dihydro
oxo
fluoro
Prior art date
Application number
SK1195-2001A
Other languages
English (en)
Slovak (sk)
Other versions
SK11952001A3 (sk
Inventor
Hubert Rast
Thomas Himmler
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of SK11952001A3 publication Critical patent/SK11952001A3/sk
Publication of SK285562B6 publication Critical patent/SK285562B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SK1195-2001A 1999-02-26 2000-02-14 Kryštálová modifikácia C kyseliny 8-kyano-1-cyklopropyl-7-(1S,6S- 2,8-diazabicyklo[4.3.0]nonan-8-yl)-6-fluór-1,4-dihydro-4-oxo-3- chinolínkarboxylovej, spôsob jej výroby a jej použitie SK285562B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19908449A DE19908449A1 (de) 1999-02-26 1999-02-26 Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
PCT/EP2000/001202 WO2000052009A1 (fr) 1999-02-26 2000-02-14 Modification cristalline c de l'acide 8-cyano -1- cyclopropyl -7-(1s, 6s-2,8- diazabicyclo -[4.3.0] nonan -8-yl) -6-fluoro -1,4- dihydro -4-oxo -3-quinoleine -carboxylique

Publications (2)

Publication Number Publication Date
SK11952001A3 SK11952001A3 (sk) 2001-12-03
SK285562B6 true SK285562B6 (sk) 2007-03-01

Family

ID=7899027

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1195-2001A SK285562B6 (sk) 1999-02-26 2000-02-14 Kryštálová modifikácia C kyseliny 8-kyano-1-cyklopropyl-7-(1S,6S- 2,8-diazabicyklo[4.3.0]nonan-8-yl)-6-fluór-1,4-dihydro-4-oxo-3- chinolínkarboxylovej, spôsob jej výroby a jej použitie

Country Status (26)

Country Link
US (1) US6649762B1 (fr)
EP (1) EP1155018B1 (fr)
JP (1) JP2002538158A (fr)
KR (1) KR100756471B1 (fr)
CN (1) CN1191253C (fr)
AT (1) ATE226952T1 (fr)
AU (1) AU763003B2 (fr)
BR (1) BR0008493A (fr)
CA (1) CA2362801A1 (fr)
CZ (1) CZ299700B6 (fr)
DE (2) DE19908449A1 (fr)
DK (1) DK1155018T3 (fr)
ES (1) ES2181644T3 (fr)
HK (1) HK1044948B (fr)
HU (1) HUP0200006A3 (fr)
IL (2) IL144702A0 (fr)
NO (1) NO320191B1 (fr)
NZ (1) NZ513750A (fr)
PL (1) PL349368A1 (fr)
PT (1) PT1155018E (fr)
RU (1) RU2248356C2 (fr)
SK (1) SK285562B6 (fr)
TR (1) TR200102434T2 (fr)
UA (1) UA70356C2 (fr)
WO (1) WO2000052009A1 (fr)
ZA (1) ZA200106289B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19854356A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854355A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908448A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation D von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo[4.3.0)nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino incarbonsäure
DE19908449A1 (de) * 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
DE102004015981A1 (de) * 2004-04-01 2005-10-20 Bayer Healthcare Ag Neue kirstalline Form von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE102006049520A1 (de) * 2006-10-20 2008-04-24 Bayer Healthcare Ag Verfahren zur Herstellung von Pradofloxacin

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2676521B2 (ja) 1988-03-22 1997-11-17 北陸製薬株式会社 キノロンカルボン酸化合物ｉ型結晶の製造法
AU709057B2 (en) 1994-11-18 1999-08-19 Pharmacia & Upjohn Company A new physically stable solid form of a fluoroquinolone
DE19546249A1 (de) * 1995-12-12 1997-06-19 Bayer Ag Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE19633805A1 (de) * 1996-02-23 1997-08-28 Bayer Ag Gegenenenfalls substituierte 8-Cyan-l-cyclopropyl-7-(2,8-diazabicyclo-[4.3.0]-nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäuren und ihre Derivate
CN1073112C (zh) * 1996-02-23 2001-10-17 拜尔公司 任选取代的8－氰基－1－环丙基－7－(2,8－二氮杂双环[4.3.0]壬－8－基)－6－氟－1,4－二氢－4－氧代－3－喹啉羧酸及其衍生物
DE19854356A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854355A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908448A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation D von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo[4.3.0)nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino incarbonsäure
DE19908449A1 (de) * 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure

Also Published As

Publication number Publication date
ES2181644T3 (es) 2003-03-01
US6649762B1 (en) 2003-11-18
CN1342160A (zh) 2002-03-27
DE50000700D1 (de) 2002-12-05
CZ20013064A3 (cs) 2002-01-16
IL144702A (en) 2006-07-05
RU2248356C2 (ru) 2005-03-20
NO320191B1 (no) 2005-11-07
EP1155018A1 (fr) 2001-11-21
CZ299700B6 (cs) 2008-10-22
NO20014061L (no) 2001-08-21
IL144702A0 (en) 2002-06-30
JP2002538158A (ja) 2002-11-12
BR0008493A (pt) 2002-02-05
HUP0200006A2 (en) 2002-06-29
DE19908449A1 (de) 2000-08-31
PT1155018E (pt) 2003-02-28
TR200102434T2 (tr) 2002-03-21
KR20010089630A (ko) 2001-10-06
HK1044948B (zh) 2005-10-14
HK1044948A1 (en) 2002-11-08
ATE226952T1 (de) 2002-11-15
NZ513750A (en) 2001-09-28
SK11952001A3 (sk) 2001-12-03
WO2000052009A1 (fr) 2000-09-08
EP1155018B1 (fr) 2002-10-30
ZA200106289B (en) 2002-07-31
KR100756471B1 (ko) 2007-09-07
PL349368A1 (en) 2002-07-15
HUP0200006A3 (en) 2002-08-28
NO20014061D0 (no) 2001-08-21
AU763003B2 (en) 2003-07-10
AU3154300A (en) 2000-09-21
UA70356C2 (uk) 2004-10-15
DK1155018T3 (da) 2003-02-17
CA2362801A1 (fr) 2000-09-08
CN1191253C (zh) 2005-03-02

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