SK284047B6 - Baktérie rodu Serratia obsahujúce dihydrodipikolinát syntázu desenzibilizovanú na spätnú inhibíciu L-lyzínom a ich použitie na produkciu L-lyzínu - Google Patents

Baktérie rodu Serratia obsahujúce dihydrodipikolinát syntázu desenzibilizovanú na spätnú inhibíciu L-lyzínom a ich použitie na produkciu L-lyzínu Download PDF

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Publication number
SK284047B6
SK284047B6 SK1705-97A SK170597A SK284047B6 SK 284047 B6 SK284047 B6 SK 284047B6 SK 170597 A SK170597 A SK 170597A SK 284047 B6 SK284047 B6 SK 284047B6
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Slovakia
Prior art keywords
residue
lysine
mutation
gene
replace
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Application number
SK1705-97A
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English (en)
Slovak (sk)
Other versions
SK170597A3 (en
Inventor
Hiroyuki Kojima
Yuri Ogawa
Kazue Kawamura
Konosuke Sano
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Ajinomoto Co., Inc.
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Application filed by Ajinomoto Co., Inc. filed Critical Ajinomoto Co., Inc.
Publication of SK170597A3 publication Critical patent/SK170597A3/sk
Publication of SK284047B6 publication Critical patent/SK284047B6/sk

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1217—Phosphotransferases with a carboxyl group as acceptor (2.7.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
SK1705-97A 1995-06-13 1996-03-14 Baktérie rodu Serratia obsahujúce dihydrodipikolinát syntázu desenzibilizovanú na spätnú inhibíciu L-lyzínom a ich použitie na produkciu L-lyzínu SK284047B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP14605495 1995-06-13
PCT/JP1996/000648 WO1996041871A1 (fr) 1995-06-13 1996-03-14 Procede de production de l-lysine par fermentation

Publications (2)

Publication Number Publication Date
SK170597A3 SK170597A3 (en) 1998-07-08
SK284047B6 true SK284047B6 (sk) 2004-08-03

Family

ID=15399054

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1705-97A SK284047B6 (sk) 1995-06-13 1996-03-14 Baktérie rodu Serratia obsahujúce dihydrodipikolinát syntázu desenzibilizovanú na spätnú inhibíciu L-lyzínom a ich použitie na produkciu L-lyzínu

Country Status (8)

Country Link
US (1) US5989875A (zh)
EP (1) EP0834559B1 (zh)
JP (1) JP4004065B2 (zh)
CN (1) CN1117860C (zh)
DE (1) DE69629299T2 (zh)
HU (1) HU224158B1 (zh)
SK (1) SK284047B6 (zh)
WO (1) WO1996041871A1 (zh)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4088982B2 (ja) * 1996-10-15 2008-05-21 味の素株式会社 発酵法によるｌ−アミノ酸の製造法
AU3674500A (en) 1999-04-09 2000-11-14 Ajinomoto Co., Inc. L-amino acid-producing bacteria and process for producing l-amino acid
JP2001120292A (ja) 1999-08-17 2001-05-08 Ajinomoto Co Inc 発酵法によるｌ−アミノ酸の製造法
JP2001120269A (ja) * 1999-10-22 2001-05-08 Ajinomoto Co Inc 発酵法によるｌ−リジンの製造法
US6927046B1 (en) * 1999-12-30 2005-08-09 Archer-Daniels-Midland Company Increased lysine production by gene amplification using coryneform bacteria
US7476531B2 (en) * 2001-02-13 2009-01-13 Ajinomoto Co., Inc. Method for producing L-amino acid using bacteria belonging to the genus Escherichia
BR0304860A (pt) * 2002-11-11 2004-08-31 Ajinomoto Kk Método para produzir uma substância alvo pela utilização de uma-bactéria pertencente ao gênero escherichia
ATE318926T1 (de) * 2003-05-26 2006-03-15 Ajinomoto Kk Verfahren zur herstellung von cadaverindicarboxylat und dessen verwendung zur herstellung von nylon
PL1813677T3 (pl) 2004-10-07 2019-05-31 Ajinomoto Kk Enzymatyczny sposób wytwarzania zasadowych aminokwasów
PL2262894T3 (pl) 2008-03-03 2015-02-27 Global Bio Chem Tech Group Company Limited Rekombinowany mikroorganizm i sposób wytwarzania l-lizyny
DE102009030342A1 (de) 2009-06-25 2010-12-30 Evonik Degussa Gmbh Verfahren zur fermentativen Herstellung von organisch chemischen Verbindungen
DE102011006716A1 (de) 2011-04-04 2012-10-04 Evonik Degussa Gmbh Mikroorganismus und Verfahren zur fermentativen Herstellung einer organisch-chemischen Verbindung
WO2014031724A1 (en) * 2012-08-23 2014-02-27 Bioamber Inc. Methods and microorganisms for the biological synthesis of (s)-2-amino-6-hydroxypimelate, hexamethylenediamine and 6-aminocaproate
CN103773745B (zh) * 2012-10-18 2018-03-23 中粮生物化学（安徽）股份有限公司 天冬氨酸激酶iii突变体及其宿主细胞和应用
EP2762571A1 (de) 2013-01-30 2014-08-06 Evonik Industries AG Mikroorganismus und Verfahren zur fermentativen Herstellung von Aminosäuren
WO2016179545A1 (en) * 2015-05-06 2016-11-10 Trelys, Inc. Compositions and methods for biological production of methionine
CN109295028B (zh) * 2018-11-05 2021-12-17 吉林农业大学 高酶活天冬氨酸激酶突变体、工程菌及该突变体的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0746994B2 (ja) * 1984-10-04 1995-05-24 味の素株式会社 発酵法によるｌ−アミノ酸の製造法
US5258300A (en) * 1988-06-09 1993-11-02 Molecular Genetics Research And Development Limited Partnership Method of inducing lysine overproduction in plants
DE69332974T2 (de) * 1992-03-19 2004-05-19 E.I. Du Pont De Nemours And Co., Wilmington Nukleinsäurefragmente und verfahren zur steigerung des lysin- und threoningehaltes der pflanzensamen
US5661012A (en) * 1992-11-10 1997-08-26 Ajinomoto Co., Inc. Method for the production of L-threonine by fermentation, using mutated DNA encoding aspartokinase III
US5545545A (en) * 1993-04-27 1996-08-13 Regents Of The University Of Minnesota Lysine-insensitive maize dihydrodipicolinic acid synthase
JP3029370B2 (ja) * 1993-12-03 2000-04-04 東洋製罐株式会社 飲料用消泡剤及びそれを配合してなる陽圧缶入り飲料
JPH07155184A (ja) * 1993-12-08 1995-06-20 Ajinomoto Co Inc 発酵法によるｌ−リジンの製造法

Also Published As

Publication number Publication date
EP0834559A1 (en) 1998-04-08
DE69629299T2 (de) 2004-07-01
DE69629299D1 (de) 2003-09-04
EP0834559A4 (en) 1999-09-08
US5989875A (en) 1999-11-23
HUP9900149A3 (en) 2001-08-28
WO1996041871A1 (fr) 1996-12-27
SK170597A3 (en) 1998-07-08
HU224158B1 (hu) 2005-06-28
CN1117860C (zh) 2003-08-13
CN1203629A (zh) 1998-12-30
HUP9900149A2 (hu) 1999-05-28
MX9710044A (es) 1998-10-31
EP0834559B1 (en) 2003-07-30
JP4004065B2 (ja) 2007-11-07

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SK284047B6 (sk) Baktérie rodu Serratia obsahujúce dihydrodipikolinát syntázu desenzibilizovanú na spätnú inhibíciu L-lyzínom a ich použitie na produkciu L-lyzínu
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MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20110314