SK283199B6 - Taxánové deriváty, prostriedok s ich obsahom a ich použitie - Google Patents

Taxánové deriváty, prostriedok s ich obsahom a ich použitie Download PDF

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Publication number
SK283199B6
SK283199B6 SK334-98A SK33498A SK283199B6 SK 283199 B6 SK283199 B6 SK 283199B6 SK 33498 A SK33498 A SK 33498A SK 283199 B6 SK283199 B6 SK 283199B6
Authority
SK
Slovakia
Prior art keywords
chx
taxane
hydrogen
paclitaxel
group
Prior art date
Application number
SK334-98A
Other languages
English (en)
Slovak (sk)
Other versions
SK33498A3 (en
Inventor
Eric Mayhew
Shaukat Ali
Andrew S. Janoff
Original Assignee
The Liposome Company, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Liposome Company, Inc. filed Critical The Liposome Company, Inc.
Publication of SK33498A3 publication Critical patent/SK33498A3/sk
Publication of SK283199B6 publication Critical patent/SK283199B6/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicinal Preparation (AREA)
SK334-98A 1995-09-12 1996-09-12 Taxánové deriváty, prostriedok s ich obsahom a ich použitie SK283199B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US357595P 1995-09-12 1995-09-12
PCT/US1996/014631 WO1997010234A1 (fr) 1995-09-12 1996-09-12 Derives hydrophobes de taxane favorisant l'hydrolyse

Publications (2)

Publication Number Publication Date
SK33498A3 SK33498A3 (en) 1998-08-05
SK283199B6 true SK283199B6 (sk) 2003-03-04

Family

ID=21706522

Family Applications (1)

Application Number Title Priority Date Filing Date
SK334-98A SK283199B6 (sk) 1995-09-12 1996-09-12 Taxánové deriváty, prostriedok s ich obsahom a ich použitie

Country Status (22)

Country Link
US (1) US5703117A (fr)
EP (1) EP0902783B1 (fr)
JP (1) JP4192208B2 (fr)
KR (1) KR100401220B1 (fr)
CN (1) CN1100770C (fr)
AT (2) ATE309235T1 (fr)
CA (1) CA2231750C (fr)
CZ (1) CZ288562B6 (fr)
DE (2) DE69620802T2 (fr)
DK (2) DK0902783T3 (fr)
ES (2) ES2179208T3 (fr)
HK (1) HK1016169A1 (fr)
HU (1) HU226325B1 (fr)
IL (1) IL123595A (fr)
MX (1) MX9801871A (fr)
NO (1) NO319521B1 (fr)
NZ (1) NZ318300A (fr)
PL (1) PL187738B1 (fr)
PT (1) PT902783E (fr)
SK (1) SK283199B6 (fr)
TR (1) TR199800443T1 (fr)
WO (1) WO1997010234A1 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6107332A (en) * 1995-09-12 2000-08-22 The Liposome Company, Inc. Hydrolysis-promoting hydrophobic taxane derivatives
US6667053B1 (en) * 1996-02-16 2003-12-23 Elan Pharmaceuticals, Inc. D and L etherlipid stereoisomers and liposomes
US5912264A (en) * 1997-03-03 1999-06-15 Bristol-Myers Squibb Company 6-halo-or nitrate-substituted paclitaxels
US8853260B2 (en) 1997-06-27 2014-10-07 Abraxis Bioscience, Llc Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
PT1964557E (pt) 1997-11-10 2013-02-20 Sloan Kettering Inst Cancer Processo para a produção de formulações de trióxido de arsénio
BR9911031A (pt) * 1998-05-20 2002-01-29 Liposome Co Inc Novas formulações em partìculas
US7314637B1 (en) 1999-06-29 2008-01-01 Neopharm, Inc. Method of administering liposomal encapsulated taxane
US6146659A (en) * 1998-07-01 2000-11-14 Neopharm, Inc. Method of administering liposomal encapsulated taxane
DE60004630T2 (de) * 1999-01-12 2004-06-17 Quanam Medical Corp., Santa Clara Arzneimittel und verfahren zur verabreichung von wasserunlöslichen paclitaxelderivaten
CA2385528C (fr) 1999-10-01 2013-12-10 Immunogen, Inc. Compositions et methodes de traitement du cancer utilisant des immunoconjugues et des agents chimiotherapeutiques
CA2410632A1 (fr) 2000-06-22 2001-12-27 David S. Garvey Taxanes nitroses et nitrosyles, compositions et procedes d'utilisation
US6607689B1 (en) * 2000-08-29 2003-08-19 Micron Technology, Inc. Layer thickness control for stereolithography utilizing variable liquid elevation and laser focal length
EP1304103B1 (fr) * 2001-10-22 2008-12-31 Viroblock SA Vesicles non-phospholipidiques (npLV) et leur utilisation en cosmetique, therapeutique et preventive
EP1461056A4 (fr) * 2001-11-26 2006-01-25 Supergen Inc Procede de preparation et d'utilisation d'huile de ricin polyoxyethylee dans des compositions pharmaceutiques
AU2003249882B2 (en) * 2002-06-26 2008-09-18 Medigene Ag Novel method of stabilizing diagnostic and therapeutic compounds in a cationic carrier system
WO2004069224A2 (fr) 2003-02-03 2004-08-19 Neopharm, Inc. Taxane liposomal encapsule, stable, sterile et filtrable et autres medicament antineoplasiques
JP5139814B2 (ja) * 2005-02-18 2013-02-06 アブラクシス バイオサイエンス リミテッド ライアビリティー カンパニー 医療装置に結合した改善された疎水性を有した薬剤
WO2006110862A2 (fr) * 2005-04-12 2006-10-19 Wisconsin Alumni Research Foundation Composition micellaire polymere et medicament contenu dans celle-ci
JP2011517683A (ja) * 2008-04-10 2011-06-16 アブラクシス バイオサイエンス， エルエルシー 疎水性タキサン誘導体の組成物およびその使用
AU2009234127B2 (en) * 2008-04-10 2015-04-30 Abraxis Bioscience, Llc Compositions of hydrophobic taxane derivatives and uses thereof
WO2011038278A2 (fr) 2009-09-25 2011-03-31 Wisconsin Alumni Research Foundation Encapsulation d'agents thérapeutiques dans des micelles
CN105503844A (zh) * 2015-12-11 2016-04-20 上海大学 C-13和c-7位结构改造的紫杉醇类化合物及其制备方法
CN111004195B (zh) * 2019-12-03 2022-01-28 沈阳药科大学 卡巴他赛弱碱性衍生物及其制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5278324A (en) * 1990-08-28 1994-01-11 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
EP0626953A4 (fr) * 1992-12-23 1995-05-03 Bristol Myers Squibb Co Nouveaux taxanes a chaines laterales et leurs intermediaires.
IL108316A (en) * 1993-01-15 2006-10-31 Univ Florida State History of C-10 Texan and pharmaceuticals containing them
US5580899A (en) * 1995-01-09 1996-12-03 The Liposome Company, Inc. Hydrophobic taxane derivatives

Also Published As

Publication number Publication date
MX9801871A (es) 1998-05-31
ATE309235T1 (de) 2005-11-15
ES2252347T3 (es) 2006-05-16
AU706290B2 (en) 1999-06-10
WO1997010234A1 (fr) 1997-03-20
ES2179208T3 (es) 2003-01-16
HK1016169A1 (en) 1999-10-29
DE69635428T2 (de) 2006-06-14
PT902783E (pt) 2002-09-30
DE69620802T2 (de) 2002-10-10
PL325477A1 (en) 1998-07-20
TR199800443T1 (xx) 1998-06-22
PL187738B1 (pl) 2004-09-30
DK0902783T3 (da) 2002-07-22
HU226325B1 (en) 2008-08-28
NO981071D0 (no) 1998-03-11
CZ288562B6 (cs) 2001-07-11
CZ71198A3 (cs) 1998-07-15
EP0902783A4 (fr) 1999-03-24
NO319521B1 (no) 2005-08-22
CN1100770C (zh) 2003-02-05
SK33498A3 (en) 1998-08-05
CA2231750A1 (fr) 1997-03-20
EP0902783B1 (fr) 2002-04-17
DE69620802D1 (de) 2002-05-23
US5703117A (en) 1997-12-30
CA2231750C (fr) 2006-07-11
IL123595A (en) 2000-10-31
HUP9901433A2 (hu) 2001-04-28
EP0902783A1 (fr) 1999-03-24
JP4192208B2 (ja) 2008-12-10
KR100401220B1 (ko) 2004-03-20
NZ318300A (en) 1999-08-30
HUP9901433A3 (en) 2001-05-28
KR19990044409A (ko) 1999-06-25
IL123595A0 (en) 1998-10-30
AU6975696A (en) 1997-04-01
ATE216377T1 (de) 2002-05-15
DK1229030T3 (da) 2006-02-13
JP2001519755A (ja) 2001-10-23
DE69635428D1 (de) 2005-12-15
NO981071L (no) 1998-05-12
CN1202166A (zh) 1998-12-16

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